Daniel M. Rosenbaum, Ph.D. - Publications

Affiliations: 
2005 Harvard University, Cambridge, MA, United States 
Area:
The Chemistry of Molecular Evolution

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Uchański T, Zögg T, Yin J, Yuan D, Wohlkönig A, Fischer B, Rosenbaum DM, Kobilka BK, Pardon E, Steyaert J. An improved yeast surface display platform for the screening of nanobody immune libraries. Scientific Reports. 9: 382. PMID 30674983 DOI: 10.1038/s41598-018-37212-3  0.72
2019 Dikiy I, Clark LD, Gardner KH, Rosenbaum DM. Isotopic Labeling of Eukaryotic Membrane Proteins for NMR Studies of Interactions and Dynamics. Methods in Enzymology. 614: 37-65. PMID 30611431 DOI: 10.1016/bs.mie.2018.08.030  0.72
2018 Yin J, Chapman K, Clark LD, Shao Z, Borek D, Xu Q, Wang J, Rosenbaum DM. Crystal structure of the human NK tachykinin receptor. Proceedings of the National Academy of Sciences of the United States of America. PMID 30538204 DOI: 10.1073/pnas.1812717115  0.72
2018 Clark L, Dikiy I, Rosenbaum DM, Gardner KH. On the use of Pichia pastoris for isotopic labeling of human GPCRs for NMR studies. Journal of Biomolecular Nmr. PMID 30121871 DOI: 10.1007/s10858-018-0204-3  0.72
2017 Suno R, Kimura KT, Nakane T, Yamashita K, Wang J, Fujiwara T, Yamanaka Y, Im D, Horita S, Tsujimoto H, Tawaramoto MS, Hirokawa T, Nango E, Tono K, Kameshima T, ... ... Rosenbaum DM, et al. Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA. Structure (London, England : 1993). PMID 29225076 DOI: 10.1016/j.str.2017.11.005  0.36
2017 Clark LD, Dikiy I, Chapman K, Rödström KEJ, Aramini J, LeVine MV, Khelashvili G, Rasmussen SGF, Gardner KH, Rosenbaum DM. Ligand modulation of sidechain dynamics in a wild-type human GPCR. Elife. 6. PMID 28984574 DOI: 10.7554/eLife.28505  0.72
2017 Zhou J, Li J, Rosenbaum DM, Zhuang J, Poon C, Qin P, Rivera K, Lepore J, Willette RN, Hu E, Barone FC. The prolyl 4-hydroxylase inhibitor GSK360A decreases post-stroke brain injury and sensory, motor, and cognitive behavioral deficits. Plos One. 12: e0184049. PMID 28880966 DOI: 10.1371/journal.pone.0184049  0.56
2017 Lee JY, Rosenbaum DM. Transporters Revealed. Cell. 168: 951-953. PMID 28283067 DOI: 10.1016/j.cell.2017.02.033  0.96
2016 Yin J, Rosenbaum DM. The Human Orexin/Hypocretin Receptor Crystal Structures. Current Topics in Behavioral Neurosciences. PMID 28025809 DOI: 10.1007/7854_2016_52  0.32
2016 Shao Z, Yin J, Chapman K, Grzemska M, Clark L, Wang J, Rosenbaum DM. High-resolution crystal structure of the human CB1 cannabinoid receptor. Nature. PMID 27851727 DOI: 10.1038/nature20613  0.52
2016 Lee JY, Kinch LN, Borek DM, Wang J, Wang J, Urbatsch IL, Xie XS, Grishin NV, Cohen JC, Otwinowski Z, Hobbs HH, Rosenbaum DM. Crystal structure of the human sterol transporter ABCG5/ABCG8. Nature. PMID 27144356 DOI: 10.1038/nature17666  0.96
2016 Zhang Y, Lee KM, Kinch LN, Clark L, Grishin NV, Rosenbaum DM, Brown MS, Goldstein JL, Radhakrishnan A. Direct Demonstration that Loop1 of Scap Binds to Loop7, a crucial event in cholesterol homeostasis. The Journal of Biological Chemistry. PMID 27068746 DOI: 10.1074/jbc.M116.729798  0.96
2016 Yin J, Babaoglu K, Brautigam CA, Clark L, Shao Z, Scheuermann TH, Harrell CM, Gotter AL, Roecker AJ, Winrow CJ, Renger JJ, Coleman PJ, Rosenbaum DM. Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors. Nature Structural & Molecular Biology. PMID 26950369 DOI: 10.1038/nsmb.3183  0.96
2016 Clark L, Zahm JA, Ali R, Kukula M, Bian L, Patrie SM, Gardner KH, Rosen MK, Rosenbaum DM. Erratum to: Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris. Journal of Biomolecular Nmr. PMID 26894386 DOI: 10.1007/s10858-016-0016-2  0.72
2015 Clark L, Zahm JA, Ali R, Kukula M, Bian L, Patrie SM, Gardner KH, Rosen MK, Rosenbaum DM. Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris. Journal of Biomolecular Nmr. 62: 239-45. PMID 26025061 DOI: 10.1007/s10858-015-9939-2  0.96
2015 Yin J, Mobarec JC, Kolb P, Rosenbaum DM. Crystal structure of the human OX2 orexin receptor bound to the insomnia drug suvorexant. Nature. 519: 247-50. PMID 25533960 DOI: 10.1038/nature14035  0.32
2013 Zhou J, Zhuang J, Li J, Ooi E, Bloom J, Poon C, Lax D, Rosenbaum DM, Barone FC. Long-term post-stroke changes include myelin loss, specific deficits in sensory and motor behaviors and complex cognitive impairment detected using active place avoidance. Plos One. 8: e57503. PMID 23505432 DOI: 10.1371/journal.pone.0057503  0.56
2012 Kruse AC, Hu J, Pan AC, Arlow DH, Rosenbaum DM, Rosemond E, Green HF, Liu T, Chae PS, Dror RO, Shaw DE, Weis WI, Wess J, Kobilka BK. Structure and dynamics of the M3 muscarinic acetylcholine receptor. Nature. 482: 552-6. PMID 22358844 DOI: 10.1038/nature10867  0.96
2012 Barone FC, Rosenbaum DM, Li J, Zhou J, Wang X. Animal models of ischemic stroke: Issues in translational congruency Translational Animal Models in Drug Discovery and Development. 42-66. DOI: 10.2174/978160805469511201010042  0.56
2011 David J, Melamud A, Kesner L, Roth S, Rosenbaum PS, Barone FC, Popp S, Hassen GW, Stracher A, Rosenbaum DM. A novel calpain inhibitor for treatment of transient retinal ischemia in the rat. Neuroreport. 22: 633-6. PMID 21841454 DOI: 10.1097/WNR.0b013e32834959c5  0.56
2011 Rosenbaum DM, Zhang C, Lyons JA, Holl R, Aragao D, Arlow DH, Rasmussen SG, Choi HJ, Devree BT, Sunahara RK, Chae PS, Gellman SH, Dror RO, Shaw DE, Weis WI, et al. Structure and function of an irreversible agonist-β(2) adrenoceptor complex. Nature. 469: 236-40. PMID 21228876 DOI: 10.1038/nature09665  0.96
2011 Rasmussen SG, Choi HJ, Fung JJ, Pardon E, Casarosa P, Chae PS, Devree BT, Rosenbaum DM, Thian FS, Kobilka TS, Schnapp A, Konetzki I, Sunahara RK, Gellman SH, Pautsch A, et al. Structure of a nanobody-stabilized active state of the β(2) adrenoceptor. Nature. 469: 175-80. PMID 21228869 DOI: 10.1038/nature09648  0.96
2011 Zhou J, Li J, Rosenbaum DM, Barone FC. Thrombopoietin protects the brain and improves sensorimotor functions: reduction of stroke-induced MMP-9 upregulation and blood-brain barrier injury. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 924-33. PMID 20877384 DOI: 10.1038/jcbfm.2010.171  0.56
2010 Bokoch MP, Zou Y, Rasmussen SG, Liu CW, Nygaard R, Rosenbaum DM, Fung JJ, Choi HJ, Thian FS, Kobilka TS, Puglisi JD, Weis WI, Pardo L, Prosser RS, Mueller L, et al. Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor. Nature. 463: 108-12. PMID 20054398 DOI: 10.1038/nature08650  0.96
2010 Rosenbaum DM, Rasmussen SGF, Kobilka BK. The γ2 adrenergic receptor as a model for g-protein-coupled receptor structure and activation by diffusible hormones Handbook of Cell Signaling, 2/E. 1: 163-169. DOI: 10.1016/B978-0-12-374145-5.00025-5  0.96
2009 Barone FC, Rosenbaum DM, Zhou J, Crystal H. Vascular cognitive impairment: dementia biology and translational animal models. Current Opinion in Investigational Drugs (London, England : 2000). 10: 624-37. PMID 19579168  0.56
2009 Rosenbaum DM, Rasmussen SG, Kobilka BK. The structure and function of G-protein-coupled receptors. Nature. 459: 356-63. PMID 19458711 DOI: 10.1038/nature08144  0.96
2009 Kolb P, Rosenbaum DM, Irwin JJ, Fung JJ, Kobilka BK, Shoichet BK. Structure-based discovery of beta2-adrenergic receptor ligands. Proceedings of the National Academy of Sciences of the United States of America. 106: 6843-8. PMID 19342484 DOI: 10.1073/pnas.0812657106  0.96
2009 Weis WI, Rosenbaum DM, Rasmussen SGF, Choi HJ, Thian FS, Kobilka TS, Yao XJ, Day PW, Parnot C, Fung JJ, Ratnala VRP, Kobilka BK, Cherezov V, Hanson MA, Kuhn P, et al. Crystal structures of the β2-adrenergic receptor Nato Science For Peace and Security Series a: Chemistry and Biology. 217-230. DOI: 10.1007/978-90-481-2339-1-14  0.96
2009 Weis WI, Rosenbaum DM, Rasmussen SGF, Choi HJ, Thian FS, Kobilka TS, Yao XJ, Day PW, Parnot C, Fung JJ, Ratnala VRP, Kobilka BK, Cherezov V, Hanson MA, Kuhn P, et al. Crystal structures of the β2-adrenergic receptor Nato Science For Peace and Security Series a: Chemistry and Biology. 217-230.  0.96
2007 Cherezov V, Rosenbaum DM, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Kuhn P, Weis WI, Kobilka BK, Stevens RC. High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor. Science (New York, N.Y.). 318: 1258-65. PMID 17962520 DOI: 10.1126/science.1150577  0.96
2007 Rosenbaum DM, Cherezov V, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Yao XJ, Weis WI, Stevens RC, Kobilka BK. GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function. Science (New York, N.Y.). 318: 1266-73. PMID 17962519 DOI: 10.1126/science.1150609  0.96
2007 Rasmussen SG, Choi HJ, Rosenbaum DM, Kobilka TS, Thian FS, Edwards PC, Burghammer M, Ratnala VR, Sanishvili R, Fischetti RF, Schertler GF, Weis WI, Kobilka BK. Crystal structure of the human beta2 adrenergic G-protein-coupled receptor. Nature. 450: 383-7. PMID 17952055 DOI: 10.1038/nature06325  0.96
2006 Phillips KJ, Rosenbaum DM, Liu DR. Binding and stability determinants of the PPARgamma nuclear receptor-coactivator interface as revealed by shotgun alanine scanning and in vivo selection. Journal of the American Chemical Society. 128: 11298-306. PMID 16925449 DOI: 10.1021/ja0635985  0.96
2003 Rosenbaum DM, Liu DR. Efficient and sequence-specific DNA-templated polymerization of peptide nucleic acid aldehydes. Journal of the American Chemical Society. 125: 13924-5. PMID 14611205 DOI: 10.1021/ja038058b  1
2000 Savitz SI, Erhardt JA, Anthony JV, Gupta G, Li X, Barone FC, Rosenbaum DM. The novel beta-blocker, carvedilol, provides neuroprotection in transient focal stroke. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 1197-204. PMID 10950380 DOI: 10.1097/00004647-200008000-00005  0.56
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