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Ralph E. Kleiner, Ph.D. - Publications

Affiliations: 
2011 Harvard University, Cambridge, MA, United States 
Area:
The Chemistry of Molecular Evolution
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13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Wang D, Zhang Y, Kleiner RE. Cell- and Polymerase-Selective Metabolic Labeling of Cellular RNA with 2'-Azidocytidine. Journal of the American Chemical Society. 142: 14417-14421. PMID 32786764 DOI: 10.1021/Jacs.0C04566  0.31
2019 Seo KW, Kleiner RE. YTHDF2 recognition of N1-methyladenosine (m1A)-modified RNA is associated with transcript destabilization. Acs Chemical Biology. PMID 31815430 DOI: 10.1021/Acschembio.9B00655  0.333
2019 Arguello AE, Leach RW, Kleiner RE. Selection with a Site-Specifically Modified RNA Library Reveals the Binding Preferences of N-Methyladenosine Reader Proteins. Biochemistry. PMID 31287290 DOI: 10.1021/Acs.Biochem.9B00485  0.34
2019 Zhang Y, Kleiner RE. A Metabolic Engineering Approach to Incorporate Modified Pyrimidine Nucleosides into Cellular RNA. Journal of the American Chemical Society. PMID 30735369 DOI: 10.1021/Jacs.8B11449  0.303
2016 Aleem SU, Georghiou G, Kleiner RE, Guja KE, Craddock BP, Lyczek A, Chan AI, Garcia-Diaz M, Miller WT, Liu DR, Seeliger MA. Structural and Biochemical Basis for Intracellular Kinase Inhibition by Src-specific Peptidic Macrocycles. Cell Chemical Biology. PMID 27593110 DOI: 10.1016/J.Chembiol.2016.07.017  0.475
2015 Kleiner RE, Verma P, Molloy KR, Chait BT, Kapoor TM. Chemical proteomics reveals a γH2AX-53BP1 interaction in the DNA damage response. Nature Chemical Biology. 11: 807-14. PMID 26344695 DOI: 10.1038/Nchembio.1908  0.329
2014 Maianti JP, McFedries A, Foda ZH, Kleiner RE, Du XQ, Leissring MA, Tang WJ, Charron MJ, Seeliger MA, Saghatelian A, Liu DR. Anti-diabetic activity of insulin-degrading enzyme inhibitors mediated by multiple hormones. Nature. 511: 94-8. PMID 24847884 DOI: 10.1038/Nature13297  0.454
2013 Kleiner RE, Ti SC, Kapoor TM. Site-specific chemistry on the microtubule polymer. Journal of the American Chemical Society. 135: 12520-3. PMID 23930594 DOI: 10.1021/Ja405199H  0.338
2012 Georghiou G, Kleiner RE, Pulkoski-Gross M, Liu DR, Seeliger MA. Highly specific, bisubstrate-competitive Src inhibitors from DNA-templated macrocycles. Nature Chemical Biology. 8: 366-74. PMID 22344177 DOI: 10.1038/Nchembio.792  0.504
2011 Kleiner RE, Dumelin CE, Liu DR. Small-molecule discovery from DNA-encoded chemical libraries. Chemical Society Reviews. 40: 5707-17. PMID 21674077 DOI: 10.1039/C1Cs15076F  0.487
2010 Kleiner RE, Dumelin CE, Tiu GC, Sakurai K, Liu DR. In vitro selection of a DNA-templated small-molecule library reveals a class of macrocyclic kinase inhibitors. Journal of the American Chemical Society. 132: 11779-91. PMID 20681606 DOI: 10.1021/Ja104903X  0.523
2010 Brudno Y, Birnbaum ME, Kleiner RE, Liu DR. An in vitro translation, selection and amplification system for peptide nucleic acids. Nature Chemical Biology. 6: 148-55. PMID 20081830 DOI: 10.1038/Nchembio.280  0.665
2008 Kleiner RE, Brudno Y, Birnbaum ME, Liu DR. DNA-templated polymerization of side-chain-functionalized peptide nucleic acid aldehydes. Journal of the American Chemical Society. 130: 4646-59. PMID 18341334 DOI: 10.1021/Ja0753997  0.662
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