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John P. Guilinger, Ph.D. - Publications

Affiliations: 
2014 Biology, Molecular and Cellular Harvard University, Cambridge, MA, United States 
Area:
The Chemistry of Molecular Evolution
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8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Hubbard BP, Badran AH, Zuris JA, Guilinger JP, Davis KM, Chen L, Tsai SQ, Sander JD, Joung JK, Liu DR. Continuous directed evolution of DNA-binding proteins to improve TALEN specificity. Nature Methods. 12: 939-42. PMID 26258293 DOI: 10.1038/Nmeth.3515  0.607
2015 Zuris JA, Thompson DB, Shu Y, Guilinger JP, Bessen JL, Hu JH, Maeder ML, Joung JK, Chen ZY, Liu DR. Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo. Nature Biotechnology. 33: 73-80. PMID 25357182 DOI: 10.1038/Nbt.3081  0.541
2014 Pattanayak V, Guilinger JP, Liu DR. Determining the specificities of TALENs, Cas9, and other genome-editing enzymes. Methods in Enzymology. 546: 47-78. PMID 25398335 DOI: 10.1016/B978-0-12-801185-0.00003-9  0.692
2014 McDonald RI, Guilinger JP, Mukherji S, Curtis EA, Lee WI, Liu DR. Electrophilic activity-based RNA probes reveal a self-alkylating RNA for RNA labeling. Nature Chemical Biology. 10: 1049-54. PMID 25306441 DOI: 10.1038/Nchembio.1655  0.519
2014 Guilinger JP, Thompson DB, Liu DR. Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification Nature Biotechnology. 32: 577-582. PMID 24770324 DOI: 10.1038/Nbt.2909  0.717
2014 Guilinger JP, Pattanayak V, Reyon D, Tsai SQ, Sander JD, Joung JK, Liu DR. Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity Nature Methods. 11: 429-435. PMID 24531420 DOI: 10.1038/Nmeth.2845  0.68
2014 Pattanayak V, Guilinger JP, Liu DR. Determining the specificities of TALENs, cas9, and other genome-editing enzymes Methods in Enzymology. 546: 47-78. DOI: 10.1016/B978-0-12-801185-0.00003-9  0.656
2013 Pattanayak V, Lin S, Guilinger JP, Ma E, Doudna JA, Liu DR. High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity. Nature Biotechnology. 31: 839-43. PMID 23934178 DOI: 10.1038/Nbt.2673  0.677
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