Allan Spradling - Publications

Carnegie Institution of Washington, Washington, DC, United States 
Developmental Biology, Genetics

170 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Deluca SZ, Ghildiyal M, Pang LY, Spradling AC. Differentiating female germ cells initiate Polycomb silencing by regulating PRC2-interacting proteins. Elife. 9. PMID 32773039 DOI: 10.7554/eLife.56922  1
2020 Niu W, Spradling AC. Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovary. Proceedings of the National Academy of Sciences of the United States of America. 117: 20015-20026. PMID 32759216 DOI: 10.1073/pnas.2005570117  0.56
2020 Wang C, Spradling AC. An abundant quiescent stem cell population in Malpighian tubules protects principal cells from kidney stones. Elife. 9. PMID 32175841 DOI: 10.7554/eLife.54096  1
2019 Greenblatt EJ, Obniski R, Mical C, Spradling AC. Prolonged ovarian storage of mature oocytes dramatically increases meiotic spindle instability. Elife. 8. PMID 31755866 DOI: 10.7554/eLife.49455  1
2019 Kanca O, Zirin J, Garcia-Marques J, Knight SM, Yang-Zhou D, Amador G, Chung H, Zuo Z, Ma L, He Y, Lin WW, Fang Y, Ge M, Yamamoto S, Schulze KL, ... ... Spradling AC, et al. An efficient CRISPR-based strategy to insert small and large fragments of DNA using short homology arms. Elife. 8. PMID 31674908 DOI: 10.7554/eLife.51539  1
2018 Obniski R, Sieber M, Spradling AC. Dietary Lipids Modulate Notch Signaling and Influence Adult Intestinal Development and Metabolism in Drosophila. Developmental Cell. PMID 30220569 DOI: 10.1016/j.devcel.2018.08.013  0.88
2018 Greenblatt EJ, Spradling AC. Fragile X mental retardation 1 gene enhances the translation of large autism-related proteins. Science (New York, N.Y.). 361: 709-712. PMID 30115809 DOI: 10.1126/science.aas9963  1
2018 DeLuca SZ, Spradling AC. Efficient Expression of Genes in the Drosophila Germline Using a UAS-Promoter Free of Interference by Hsp70 piRNAs. Genetics. PMID 29669732 DOI: 10.1534/genetics.118.300874  1
2018 Lee PT, Zirin J, Kanca O, Lin WW, Schulze KL, Li-Kroeger D, Tao R, Devereaux C, Hu Y, Chung V, Fang Y, He Y, Pan H, Ge M, Zuo Z, ... ... Spradling AC, et al. A gene-specificlibrary for. Elife. 7. PMID 29565247 DOI: 10.7554/eLife.35574  1
2017 Greider C, Hopkins N, Steitz J, Amon A, Asai D, Barres B, Bass B, Bassler B, Birgeneau R, Bjorkman P, Botchan M, Brugge J, Cech T, Colwell R, Craig N, ... ... Spradling A, et al. Not just Salk. Science (New York, N.Y.). 357: 1105-1106. PMID 28912235 DOI: 10.1126/science.aao6221  0.68
2017 Sieber MH, Spradling AC. The role of metabolic states in development and disease. Current Opinion in Genetics & Development. 45: 58-68. PMID 28347941 DOI: 10.1016/j.gde.2017.03.002  1
2017 Lei L, Spradling AC. Single-Cell Lineage Analysis of Oogenesis in Mice. Methods in Molecular Biology (Clifton, N.J.). 1463: 125-138. PMID 27734353 DOI: 10.1007/978-1-4939-4017-2_10  0.72
2016 Lee MC, Skora AD, Spradling AC. Identification of Genes Mediating Drosophila Follicle Cell Progenitor Differentiation by Screening for Modifiers of GAL4::UAS Variegation. G3 (Bethesda, Md.). PMID 27866148 DOI: 10.1534/g3.116.036038  0.88
2016 Losick VP, Jun AS, Spradling AC. Wound-Induced Polyploidization: Regulation by Hippo and JNK Signaling and Conservation in Mammals. Plos One. 11: e0151251. PMID 26958853 DOI: 10.1371/journal.pone.0151251  1
2016 Lei L, Spradling AC. Mouse oocytes differentiate through organelle enrichment from sister cyst germ cells. Science (New York, N.Y.). PMID 26917595 DOI: 10.1126/science.aad2156  1
2016 Sieber MH, Thomsen MB, Spradling AC. Electron Transport Chain Remodeling by GSK3 during Oogenesis Connects Nutrient State to Reproduction. Cell. 164: 420-32. PMID 26824655 DOI: 10.1016/j.cell.2015.12.020  1
2016 Spradling AC. The Carnegie Department of Embryology at 100: Looking Forward Current Topics in Developmental Biology. DOI: 10.1016/bs.ctdb.2015.11.038  1
2015 Nagarkar-Jaiswal S, DeLuca SZ, Lee PT, Lin WW, Pan H, Zuo Z, Lv J, Spradling AC, Bellen HJ. A genetic toolkit for tagging intronic MiMIC containing genes. Elife. 4. PMID 26102525 DOI: 10.7554/eLife.08469  1
2015 Nagarkar-Jaiswal S, Lee PT, Campbell ME, Chen K, Anguiano-Zarate S, Gutierrez MC, Busby T, Lin WW, He Y, Schulze KL, Booth BW, Evans-Holm M, Venken KJ, Levis RW, Spradling AC, et al. A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila. Elife. 4. PMID 25824290 DOI: 10.7554/eLife.05338  1
2015 Sieber MH, Spradling AC. Steroid Signaling Establishes a Female Metabolic State and Regulates SREBP to Control Oocyte Lipid Accumulation. Current Biology : Cb. 25: 993-1004. PMID 25802149 DOI: 10.1016/j.cub.2015.02.019  1
2015 Deady LD, Shen W, Mosure SA, Spradling AC, Sun J. Matrix metalloproteinase 2 is required for ovulation and corpus luteum formation in Drosophila. Plos Genetics. 11: e1004989. PMID 25695427 DOI: 10.1371/journal.pgen.1004989  1
2014 Lee MC, Spradling AC. The progenitor state is maintained by lysine-specific demethylase 1-mediated epigenetic plasticity during Drosophila follicle cell development. Genes & Development. 28: 2739-49. PMID 25512561 DOI: 10.1101/gad.252692.114  1
2014 Yarosh W, Spradling AC. Incomplete replication generates somatic DNA alterations within Drosophila polytene salivary gland cells. Genes & Development. 28: 1840-55. PMID 25128500 DOI: 10.1101/gad.245811.114  1
2013 Losick VP, Fox DT, Spradling AC. Polyploidization and cell fusion contribute to wound healing in the adult Drosophila epithelium. Current Biology : Cb. 23: 2224-32. PMID 24184101 DOI: 10.1016/j.cub.2013.09.029  1
2013 Marianes A, Spradling AC. Physiological and stem cell compartmentalization within the Drosophila midgut. Elife. 2: e00886. PMID 23991285 DOI: 10.7554/eLife.00886  1
2013 Lei L, Spradling AC. Female mice lack adult germ-line stem cells but sustain oogenesis using stable primordial follicles. Proceedings of the National Academy of Sciences of the United States of America. 110: 8585-90. PMID 23630252 DOI: 10.1073/pnas.1306189110  1
2013 Sun J, Spradling AC. Ovulation in Drosophila is controlled by secretory cells of the female reproductive tract. Elife. 2: e00415. PMID 23599892 DOI: 10.7554/eLife.00415  1
2013 Lei L, Spradling AC. Mouse primordial germ cells produce cysts that partially fragment prior to meiosis. Development (Cambridge, England). 140: 2075-81. PMID 23578925 DOI: 10.1242/dev.093864  1
2012 Morris LX, Spradling AC. Steroid signaling within Drosophila ovarian epithelial cells sex-specifically modulates early germ cell development and meiotic entry. Plos One. 7: e46109. PMID 23056242 DOI: 10.1371/journal.pone.0046109  1
2012 Sun J, Spradling AC. NR5A nuclear receptor Hr39 controls three-cell secretory unit formation in Drosophila female reproductive glands. Current Biology : Cb. 22: 862-71. PMID 22560612 DOI: 10.1016/j.cub.2012.03.059  1
2011 Venken KJ, Schulze KL, Haelterman NA, Pan H, He Y, Evans-Holm M, Carlson JW, Levis RW, Spradling AC, Hoskins RA, Bellen HJ. MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes. Nature Methods. 8: 737-43. PMID 21985007 DOI: 10.1038/nmeth.1662  1
2011 Spradling AC, Bellen HJ, Hoskins RA. Drosophila P elements preferentially transpose to replication origins. Proceedings of the National Academy of Sciences of the United States of America. 108: 15948-53. PMID 21896744 DOI: 10.1073/pnas.1112960108  1
2011 Spradling AC. The living-tissue microscope: the importance of studying stem cells in their natural, undisturbed microenvironment. The Journal of Pathology. 225: 161-2. PMID 21792940 DOI: 10.1002/path.2943  1
2011 Spradling A, Fuller MT, Braun RE, Yoshida S. Germline stem cells. Cold Spring Harbor Perspectives in Biology. 3: a002642. PMID 21791699 DOI: 10.1101/cshperspect.a002642  1
2011 Losick VP, Morris LX, Fox DT, Spradling A. Drosophila stem cell niches: a decade of discovery suggests a unified view of stem cell regulation. Developmental Cell. 21: 159-71. PMID 21763616 DOI: 10.1016/j.devcel.2011.06.018  1
2011 Tootle TL, Williams D, Hubb A, Frederick R, Spradling A. Drosophila eggshell production: identification of new genes and coordination by Pxt. Plos One. 6: e19943. PMID 21637834 DOI: 10.1371/journal.pone.0019943  1
2011 Morris LX, Spradling AC. Long-term live imaging provides new insight into stem cell regulation and germline-soma coordination in the Drosophila ovary. Development (Cambridge, England). 138: 2207-15. PMID 21558370 DOI: 10.1242/dev.065508  1
2011 Bellen HJ, Levis RW, He Y, Carlson JW, Evans-Holm M, Bae E, Kim J, Metaxakis A, Savakis C, Schulze KL, Hoskins RA, Spradling AC. The Drosophila gene disruption project: progress using transposons with distinctive site specificities. Genetics. 188: 731-43. PMID 21515576 DOI: 10.1534/genetics.111.126995  1
2010 Fox DT, Gall JG, Spradling AC. Error-prone polyploid mitosis during normal Drosophila development. Genes & Development. 24: 2294-302. PMID 20952538 DOI: 10.1101/gad.1952710  1
2010 Spradling A, Fan CM. Counterfeiting the family jewels. Cell Stem Cell. 6: 405-6. PMID 20452312 DOI: 10.1016/j.stem.2010.04.012  1
2010 Skora AD, Spradling AC. Epigenetic stability increases extensively during Drosophila follicle stem cell differentiation. Proceedings of the National Academy of Sciences of the United States of America. 107: 7389-94. PMID 20368445 DOI: 10.1073/pnas.1003180107  1
2010 Nystul T, Spradling A. Regulation of epithelial stem cell replacement and follicle formation in the Drosophila ovary. Genetics. 184: 503-15. PMID 19948890 DOI: 10.1534/genetics.109.109538  1
2010 Nystul T, Spradling A. Regulation of epithelial stem cell replacement and follicle formation in the drosophila ovary (Genetics 184 (503-515)) Genetics. 186: 1504. DOI: 10.1534/genetics.110.124404  1
2009 Fox DT, Spradling AC. The Drosophila hindgut lacks constitutively active adult stem cells but proliferates in response to tissue damage. Cell Stem Cell. 5: 290-7. PMID 19699165 DOI: 10.1016/j.stem.2009.06.003  1
2009 Cox RT, Spradling AC. Clueless, a conserved Drosophila gene required for mitochondrial subcellular localization, interacts genetically with parkin. Disease Models & Mechanisms. 2: 490-9. PMID 19638420 DOI: 10.1242/dmm.002378  1
2009 Goll MG, Anderson R, Stainier DY, Spradling AC, Halpern ME. Transcriptional silencing and reactivation in transgenic zebrafish. Genetics. 182: 747-55. PMID 19433629 DOI: 10.1534/genetics.109.102079  1
2009 Buszczak M, Paterno S, Spradling AC. Drosophila stem cells share a common requirement for the histone H2B ubiquitin protease scrawny. Science (New York, N.Y.). 323: 248-51. PMID 19039105 DOI: 10.1126/science.1165678  1
2008 Spradling AC. Stem cells: Makeshift sperm production. Nature. 456: 583-5. PMID 19052613 DOI: 10.1038/456583a  1
2008 Spradling AC, Nystul T, Lighthouse D, Morris L, Fox D, Cox R, Tootle T, Frederick R, Skora A. Stem cells and their niches: integrated units that maintain Drosophila tissues. Cold Spring Harbor Symposia On Quantitative Biology. 73: 49-57. PMID 19022764 DOI: 10.1101/sqb.2008.73.023  1
2008 Spradling A. The 2008 Thomas Hunt Morgan Medal. Michael Ashburner. Genetics. 178: 1123-4. PMID 18385103 DOI: 10.1534/genetics.104.017832  1
2008 Lighthouse DV, Buszczak M, Spradling AC. New components of the Drosophila fusome suggest it plays novel roles in signaling and transport. Developmental Biology. 317: 59-71. PMID 18355804 DOI: 10.1016/j.ydbio.2008.02.009  1
2008 Morrison SJ, Spradling AC. Stem cells and niches: mechanisms that promote stem cell maintenance throughout life. Cell. 132: 598-611. PMID 18295578 DOI: 10.1016/j.cell.2008.01.038  1
2008 Tootle TL, Spradling AC. Drosophila Pxt: a cyclooxygenase-like facilitator of follicle maturation. Development (Cambridge, England). 135: 839-47. PMID 18216169 DOI: 10.1242/dev.017590  1
2008 Allen AK, Spradling AC. The Sf1-related nuclear hormone receptor Hr39 regulates Drosophila female reproductive tract development and function. Development (Cambridge, England). 135: 311-21. PMID 18077584 DOI: 10.1242/dev.015156  1
2007 Nystul T, Spradling A. An epithelial niche in the Drosophila ovary undergoes long-range stem cell replacement. Cell Stem Cell. 1: 277-85. PMID 18371362 DOI: 10.1016/j.stem.2007.07.009  1
2007 Fuller MT, Spradling AC. Male and female Drosophila germline stem cells: two versions of immortality. Science (New York, N.Y.). 316: 402-4. PMID 17446390 DOI: 10.1126/science.1140861  1
2007 Ohlstein B, Spradling A. Multipotent Drosophila intestinal stem cells specify daughter cell fates by differential notch signaling. Science (New York, N.Y.). 315: 988-92. PMID 17303754 DOI: 10.1126/science.1136606  1
2007 Spradling AC, Zheng Y. Developmental biology. The mother of all stem cells? Science (New York, N.Y.). 315: 469-70. PMID 17255500 DOI: 10.1126/science.1138237  1
2007 Buszczak M, Paterno S, Lighthouse D, Bachman J, Planck J, Owen S, Skora AD, Nystul TG, Ohlstein B, Allen A, Wilhelm JE, Murphy TD, Levis RW, Matunis E, Srivali N, ... ... Spradling AC, et al. The carnegie protein trap library: a versatile tool for Drosophila developmental studies. Genetics. 175: 1505-31. PMID 17194782 DOI: 10.1534/genetics.106.065961  1
2007 Pepling ME, Wilhelm JE, O'Hara AL, Gephardt GW, Spradling AC. Mouse oocytes within germ cell cysts and primordial follicles contain a Balbiani body. Proceedings of the National Academy of Sciences of the United States of America. 104: 187-92. PMID 17189423 DOI: 10.1073/pnas.0609923104  1
2006 Spradling AC. Learning the common language of genetics. Genetics. 174: 1-3. PMID 16988105  1
2006 Nystul TG, Spradling AC. Breaking out of the mold: diversity within adult stem cells and their niches. Current Opinion in Genetics & Development. 16: 463-8. PMID 16919446 DOI: 10.1016/j.gde.2006.08.003  1
2006 Cox RT, Spradling AC. Milton controls the early acquisition of mitochondria by Drosophila oocytes. Development (Cambridge, England). 133: 3371-7. PMID 16887820 DOI: 10.1242/dev.02514  1
2006 Spradling A, Ganetsky B, Hieter P, Johnston M, Olson M, Orr-Weaver T, Rossant J, Sanchez A, Waterston R. New roles for model genetic organisms in understanding and treating human disease: report from the 2006 Genetics Society of America meeting. Genetics. 172: 2025-32. PMID 16636111  1
2006 Buszczak M, Spradling AC. Searching chromatin for stem cell identity. Cell. 125: 233-6. PMID 16630812 DOI: 10.1016/j.cell.2006.04.004  1
2006 Buszczak M, Spradling AC. The Drosophila P68 RNA helicase regulates transcriptional deactivation by promoting RNA release from chromatin. Genes & Development. 20: 977-89. PMID 16598038 DOI: 10.1101/gad.1396306  1
2006 Ohlstein B, Spradling A. The adult Drosophila posterior midgut is maintained by pluripotent stem cells. Nature. 439: 470-4. PMID 16340960 DOI: 10.1038/nature04333  1
2006 Tulin A, Naumova NM, Menon AK, Spradling AC. Drosophila poly(ADP-ribose) glycohydrolase mediates chromatin structure and SIR2-dependent silencing. Genetics. 172: 363-71. PMID 16219773 DOI: 10.1534/genetics.105.049239  1
2005 Decotto E, Spradling AC. The Drosophila ovarian and testis stem cell niches: similar somatic stem cells and signals. Developmental Cell. 9: 501-10. PMID 16198292 DOI: 10.1016/j.devcel.2005.08.012  1
2005 Kai T, Williams D, Spradling AC. The expression profile of purified Drosophila germline stem cells. Developmental Biology. 283: 486-502. PMID 15927177 DOI: 10.1016/j.ydbio.2005.04.018  1
2004 Ohlstein B, Kai T, Decotto E, Spradling A. The stem cell niche: theme and variations. Current Opinion in Cell Biology. 16: 693-9. PMID 15530783 DOI: 10.1016/  1
2004 Bellen HJ, Levis RW, Liao G, He Y, Carlson JW, Tsang G, Evans-Holm M, Hiesinger PR, Schulze KL, Rubin GM, Hoskins RA, Spradling AC. The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. Genetics. 167: 761-81. PMID 15238527 DOI: 10.1534/genetics.104.026427  1
2004 Kai T, Spradling A. Differentiating germ cells can revert into functional stem cells in Drosophila melanogaster ovaries. Nature. 428: 564-9. PMID 15024390 DOI: 10.1038/nature02436  1
2004 Spradling AC. Stem cells: more like a man. Nature. 428: 133-4. PMID 15014482 DOI: 10.1038/428133b  1
2004 Drummond-Barbosa D, Spradling AC. Alpha-endosulfine, a potential regulator of insulin secretion, is required for adult tissue growth control in Drosophila. Developmental Biology. 266: 310-21. PMID 14738879 DOI: 10.1016/j.ydbio.2003.10.028  1
2003 Tulin A, Chinenov Y, Spradling A. Regulation of chromatin structure and gene activity by poly(ADP-ribose) polymerases. Current Topics in Developmental Biology. 56: 55-83. PMID 14584726 DOI: 10.1016/S0070-2153(03)01007-X  1
2003 Kai T, Spradling A. An empty Drosophila stem cell niche reactivates the proliferation of ectopic cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 4633-8. PMID 12676994 DOI: 10.1073/pnas.0830856100  1
2003 Cox RT, Spradling AC. A Balbiani body and the fusome mediate mitochondrial inheritance during Drosophila oogenesis. Development (Cambridge, England). 130: 1579-90. PMID 12620983 DOI: 10.1242/dev.00365  1
2003 Tulin A, Spradling A. Chromatin loosening by poly(ADP)-ribose polymerase (PARP) at Drosophila puff loci. Science (New York, N.Y.). 299: 560-2. PMID 12543974 DOI: 10.1126/science.1078764  1
2002 Tulin A, Stewart D, Spradling AC. The Drosophila heterochromatic gene encoding poly(ADP-ribose) polymerase (PARP) is required to modulate chromatin structure during development. Genes & Development. 16: 2108-19. PMID 12183365 DOI: 10.1101/gad.1003902  1
2001 Spradling A, Drummond-Barbosa D, Kai T. Stem cells find their niche. Nature. 414: 98-104. PMID 11689954 DOI: 10.1038/35102160  1
2001 Frydman HM, Spradling AC. The receptor-like tyrosine phosphatase lar is required for epithelial planar polarity and for axis determination within drosophila ovarian follicles. Development (Cambridge, England). 128: 3209-20. PMID 11688569  1
2001 Calvi BR, Spradling AC. The nuclear location and chromatin organization of active chorion amplification origins. Chromosoma. 110: 159-72. PMID 11513291  1
2001 Pepling ME, Spradling AC. Mouse ovarian germ cell cysts undergo programmed breakdown to form primordial follicles. Developmental Biology. 234: 339-51. PMID 11397004 DOI: 10.1006/dbio.2001.0269  1
2001 Drummond-Barbosa D, Spradling AC. Stem cells and their progeny respond to nutritional changes during Drosophila oogenesis. Developmental Biology. 231: 265-78. PMID 11180967 DOI: 10.1006/dbio.2000.0135  1
2001 Spradling AC. Reflections on the Drosophila genome Functional and Integrative Genomics. 1: 221-222. DOI: 10.1007/s101420100034  1
2000 Xie T, Spradling AC. A niche maintaining germ line stem cells in the Drosophila ovary. Science (New York, N.Y.). 290: 328-30. PMID 11030649 DOI: 10.1126/science.290.5490.328  1
2000 Grieder NC, de Cuevas M, Spradling AC. The fusome organizes the microtubule network during oocyte differentiation in Drosophila. Development (Cambridge, England). 127: 4253-64. PMID 10976056  1
2000 Lilly MA, de Cuevas M, Spradling AC. Cyclin A associates with the fusome during germline cyst formation in the Drosophila ovary. Developmental Biology. 218: 53-63. PMID 10644410 DOI: 10.1006/dbio.1999.9570  1
1999 Spradling AC. ORC binding, gene amplification, and the nature of metazoan replication origins. Genes & Development. 13: 2619-23. PMID 10541547 DOI: 10.1101/gad.13.20.2619  1
1999 Ashburner M, Misra S, Roote J, Lewis SE, Blazej R, Davis T, Doyle C, Galle R, George R, Harris N, Hartzell G, Harvey D, Hong L, Houston K, Hoskins R, ... ... Spradling A, et al. An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster: the Adh region. Genetics. 153: 179-219. PMID 10471707  1
1999 Spradling AC, Stern D, Beaton A, Rhem EJ, Laverty T, Mozden N, Misra S, Rubin GM. The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes. Genetics. 153: 135-77. PMID 10471706  1
1999 Calvi BR, Spradling AC. Chorion gene amplification in Drosophila: A model for metazoan origins of DNA replication and S-phase control. Methods (San Diego, Calif.). 18: 407-17. PMID 10455001 DOI: 10.1006/meth.1999.0799  1
1999 Pepling ME, de Cuevas M, Spradling AC. Germline cysts: a conserved phase of germ cell development? Trends in Cell Biology. 9: 257-62. PMID 10370240 DOI: 10.1016/S0962-8924(99)01594-9  0.6
1999 Dej KJ, Spradling AC. The endocycle controls nurse cell polytene chromosome structure during Drosophila oogenesis. Development (Cambridge, England). 126: 293-303. PMID 9847243  1
1998 Xie T, Spradling AC. decapentaplegic is essential for the maintenance and division of germline stem cells in the Drosophila ovary. Cell. 94: 251-60. PMID 9695953 DOI: 10.1016/S0092-8674(00)81424-5  1
1998 Pepling ME, Spradling AC. Female mouse germ cells form synchronously dividing cysts. Development (Cambridge, England). 125: 3323-8. PMID 9693136  1
1998 de Cuevas M, Spradling AC. Morphogenesis of the Drosophila fusome and its implications for oocyte specification. Development (Cambridge, England). 125: 2781-9. PMID 9655801  1
1998 Calvi BR, Lilly MA, Spradling AC. Cell cycle control of chorion gene amplification. Genes & Development. 12: 734-44. PMID 9499407  1
1997 Spradling AC, de Cuevas M, Drummond-Barbosa D, Keyes L, Lilly M, Pepling M, Xie T. The Drosophila germarium: stem cells, germ line cysts, and oocytes. Cold Spring Harbor Symposia On Quantitative Biology. 62: 25-34. PMID 9598333  1
1997 de Cuevas M, Lilly MA, Spradling AC. Germline cyst formation in Drosophila. Annual Review of Genetics. 31: 405-28. PMID 9442902 DOI: 10.1146/annurev.genet.31.1.405  1
1997 Spradling AC. The Carnegie Institution of Washington, Department of Embryology. Molecular Medicine (Cambridge, Mass.). 3: 417-9. PMID 9260153  1
1997 Schneider LE, Spradling AC. The Drosophila G-protein-coupled receptor kinase homologue Gprk2 is required for egg morphogenesis. Development (Cambridge, England). 124: 2591-602. PMID 9217001  1
1997 Lin H, Spradling AC. A novel group of pumilio mutations affects the asymmetric division of germline stem cells in the Drosophila ovary. Development (Cambridge, England). 124: 2463-76. PMID 9199372  1
1997 Keyes LN, Spradling AC. The Drosophila gene fs(2)cup interacts with otu to define a cytoplasmic pathway required for the structure and function of germ-line chromosomes. Development (Cambridge, England). 124: 1419-31. PMID 9118812  1
1997 Landis G, Kelley R, Spradling AC, Tower J. The k43 gene, required for chorion gene amplification and diploid cell chromosome replication, encodes the Drosophila homolog of yeast origin recognition complex subunit 2. Proceedings of the National Academy of Sciences of the United States of America. 94: 3888-92. PMID 9108074 DOI: 10.1073/pnas.94.8.3888  1
1996 de Cuevas M, Lee JK, Spradling AC. alpha-spectrin is required for germline cell division and differentiation in the Drosophila ovary. Development (Cambridge, England). 122: 3959-68. PMID 9012516  1
1996 Forbes AJ, Spradling AC, Ingham PW, Lin H. The role of segment polarity genes during early oogenesis in Drosophila. Development (Cambridge, England). 122: 3283-94. PMID 8898240  1
1996 Lilly MA, Spradling AC. The Drosophila endocycle is controlled by Cyclin E and lacks a checkpoint ensuring S-phase completion. Genes & Development. 10: 2514-26. PMID 8843202  0.92
1996 Forbes AJ, Lin H, Ingham PW, Spradling AC. hedgehog is required for the proliferation and specification of ovarian somatic cells prior to egg chamber formation in Drosophila. Development (Cambridge, England). 122: 1125-35. PMID 8620839  1
1995 Margolis J, Spradling A. Identification and behavior of epithelial stem cells in the Drosophila ovary. Development (Cambridge, England). 121: 3797-807. PMID 8582289  1
1995 Lin H, Spradling AC. Fusome asymmetry and oocyte determination in Drosophila. Developmental Genetics. 16: 6-12. PMID 7758245 DOI: 10.1002/dvg.1020160104  1
1995 Zhang P, Spradling AC. The Drosophila salivary gland chromocenter contains highly polytenized subdomains of mitotic heterochromatin. Genetics. 139: 659-70. PMID 7713423  1
1995 Spradling AC, Stern DM, Kiss I, Roote J, Laverty T, Rubin GM. Gene disruptions using P transposable elements: an integral component of the Drosophila genome project. Proceedings of the National Academy of Sciences of the United States of America. 92: 10824-30. PMID 7479892 DOI: 10.1073/pnas.92.24.10824  1
1994 Zhang P, Spradling AC. Insertional mutagenesis of Drosophila heterochromatin with single P elements. Proceedings of the National Academy of Sciences of the United States of America. 91: 3539-43. PMID 8170943  1
1994 Thompson-Stewart D, Karpen GH, Spradling AC. A transposable element can drive the concerted evolution of tandemly repetitious DNA. Proceedings of the National Academy of Sciences of the United States of America. 91: 9042-6. PMID 8090766 DOI: 10.1073/pnas.91.19.9042  1
1994 Spradling AC. Transposable elements and the evolution of heterochromatin. Society of General Physiologists Series. 49: 69-83. PMID 7939905  1
1994 Glaser RL, Spradling AC. Unusual properties of genomic DNA molecules spanning the euchromatic-heterochromatic junction of a Drosophila minichromosome. Nucleic Acids Research. 22: 5068-75. PMID 7800501  1
1994 Lin H, Yue L, Spradling AC. The Drosophila fusome, a germline-specific organelle, contains membrane skeletal proteins and functions in cyst formation. Development (Cambridge, England). 120: 947-56. PMID 7600970  1
1993 Spradling AC. Germline cysts: communes that work. Cell. 72: 649-51. PMID 8453660 DOI: 10.1016/0092-8674(93)90393-5  1
1993 Zhang P, Spradling AC. Efficient and dispersed local P element transposition from Drosophila females. Genetics. 133: 361-73. PMID 8382178  1
1993 Tower J, Karpen GH, Craig N, Spradling AC. Preferential transposition of Drosophila P elements to nearby chromosomal sites. Genetics. 133: 347-59. PMID 8382177  1
1993 Lin H, Spradling AC. Germline stem cell division and egg chamber development in transplanted Drosophila germaria. Developmental Biology. 159: 140-52. PMID 8365558 DOI: 10.1006/dbio.1993.1228  1
1993 Heck MM, Pereira A, Pesavento P, Yannoni Y, Spradling AC, Goldstein LS. The kinesin-like protein KLP61F is essential for mitosis in Drosophila. The Journal of Cell Biology. 123: 665-79. PMID 8227131  1
1993 Spradling AC. Position effect variegation and genomic instability. Cold Spring Harbor Symposia On Quantitative Biology. 58: 585-96. PMID 7956073  1
1992 Montell DJ, Rorth P, Spradling AC. slow border cells, a locus required for a developmentally regulated cell migration during oogenesis, encodes Drosophila C/EBP. Cell. 71: 51-62. PMID 1394432 DOI: 10.1016/0092-8674(92)90265-E  1
1992 Yue L, Spradling AC. hu-li tai shao, a gene required for ring canal formation during Drosophila oogenesis, encodes a homolog of adducin. Genes & Development. 6: 2443-54. PMID 1340461  1
1992 Karpen GH, Spradling AC. Analysis of subtelomeric heterochromatin in the Drosophila minichromosome Dp1187 by single P element insertional mutagenesis. Genetics. 132: 737-53. PMID 1334894  1
1992 Glaser RL, Karpen GH, Spradling AC. Replication forks are not found in a Drosophila minichromosome demonstrating a gradient of polytenization. Chromosoma. 102: 15-9. PMID 1291225 DOI: 10.1007/BF00352285  1
1991 Montell DJ, Keshishian H, Spradling AC. Laser ablation studies of the role of the Drosophila oocyte nucleus in pattern formation. Science (New York, N.Y.). 254: 290-3. PMID 1925585  1
1991 Berg CA, Spradling AC. Studies on the rate and site-specificity of P element transposition. Genetics. 127: 515-24. PMID 1849859  1
1990 Cooley L, Thompson D, Spradling AC. Constructing deletions with defined endpoints in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 87: 3170-3. PMID 2326275  1
1990 McKearin DM, Spradling AC. bag-of-marbles: a Drosophila gene required to initiate both male and female gametogenesis. Genes & Development. 4: 2242-51. PMID 2279698  1
1990 Karpen GH, Spradling AC. Reduced DNA polytenization of a minichromosome region undergoing position-effect variegation in Drosophila. Cell. 63: 97-107. PMID 2208283 DOI: 10.1016/0092-8674(90)90291-L  1
1990 Heck MM, Spradling AC. Multiple replication origins are used during Drosophila chorion gene amplification. The Journal of Cell Biology. 110: 903-14. PMID 2157721  1
1990 Spradling AC, Karpen GH. Sixty years of mystery. Genetics. 126: 779-84. PMID 2127578  1
1990 Finkelstein R, Smouse D, Capaci TM, Spradling AC, Perrimon N. The orthodenticle gene encodes a novel homeo domain protein involved in the development of the Drosophila nervous system and ocellar visual structures. Genes & Development. 4: 1516-27. PMID 1979296  1
1989 Orr-Weaver TL, Johnston CG, Spradling AC. The role of ACE3 in Drosophila chorion gene amplification. The Embo Journal. 8: 4153-62. PMID 2556262  1
1989 Cooley L, Berg C, Kelley R, McKearin D, Spradling A. Identifying and cloning Drosophila genes by single P element insertional mutagenesis. Progress in Nucleic Acid Research and Molecular Biology. 36: 99-109. PMID 2544018  1
1988 Cooley L, Berg C, Spradling A. Controlling P element insertional mutagenesis. Trends in Genetics : Tig. 4: 254-8. PMID 2853469 DOI: 10.1016/0168-9525(88)90032-7  1
1988 Cooley L, Kelley R, Spradling A. Insertional mutagenesis of the Drosophila genome with single P elements. Science (New York, N.Y.). 239: 1121-8. PMID 2830671  1
1987 Spradling A, Orr-Weaver T. Regulation of DNA replication during Drosophila development. Annual Review of Genetics. 21: 373-403. PMID 3327470 DOI: 10.1146/  1
1987 Spradling A. Gene amplification in dipteran chromosomes. Results and Problems in Cell Differentiation. 14: 199-212. PMID 3303211  1
1987 Spradling AC, de Cicco DV, Wakimoto BT, Levine JF, Kalfayan LJ, Cooley L. Amplification of the X-linked Drosophila chorion gene cluster requires a region upstream from the s38 chorion gene. The Embo Journal. 6: 1045-53. PMID 3036489  1
1986 Orr-Weaver TL, Spradling AC. Drosophila chorion gene amplification requires an upstream region regulating s18 transcription. Molecular and Cellular Biology. 6: 4624-33. PMID 3099171  1
1986 Parks S, Wakimoto B, Spradling A. Replication and expression of an X-linked cluster of Drosophila chorion genes. Developmental Biology. 117: 294-305. PMID 3091430 DOI: 10.1016/0012-1606(86)90372-6  1
1986 Wakimoto BT, Kalfayan LJ, Spradling AC. Developmentally regulated expression of Drosophila chorion genes introduced at diverse chromosomal positions. Journal of Molecular Biology. 187: 33-45. PMID 2420996 DOI: 10.1016/0022-2836(86)90404-3  1
1985 Levine J, Spradling A. DNA sequence of a 3.8 kilobase pair region controlling Drosophila chorion gene amplification. Chromosoma. 92: 136-42. PMID 3924529 DOI: 10.1007/BF00328465  1
1985 Kalfayan L, Levine J, Orr-Weaver T, Parks S, Wakimoto B, de Cicco D, Spradling A. Localization of sequences regulating Drosophila chorion gene amplification and expression. Cold Spring Harbor Symposia On Quantitative Biology. 50: 527-35. PMID 3868491 DOI: 10.1101/SQB.1985.050.01.065  1
1984 Kalfayan L, Wakimoto B, Spradling A. Analysis of transcriptional regulation of the s38 chorion gene of Drosophila by P element-mediated transformation. Journal of Embryology and Experimental Morphology. 83: 137-46. PMID 6099848  1
1984 de Cicco DV, Spradling AC. Localization of a cis-acting element responsible for the developmentally regulated amplification of Drosophila chorion genes. Cell. 38: 45-54. PMID 6088075 DOI: 10.1016/0092-8674(84)90525-7  1
1983 Rubin GM, Spradling AC. Vectors for P element-mediated gene transfer in Drosophila. Nucleic Acids Research. 11: 6341-51. PMID 6312420 DOI: 10.1093/nar/11.18.6341  1
1983 Spradling AC, Rubin GM. The effect of chromosomal position on the expression of the Drosophila xanthine dehydrogenase gene. Cell. 34: 47-57. PMID 6309411 DOI: 10.1016/0092-8674(83)90135-6  1
1982 Rubin GM, Spradling AC. Genetic transformation of Drosophila with transposable element vectors. Science (New York, N.Y.). 218: 348-53. PMID 6289436  1
1982 Spradling AC, Rubin GM. Transposition of cloned P elements into Drosophila germ line chromosomes. Science (New York, N.Y.). 218: 341-7. PMID 6289435  1
1981 Spradling AC, Rubin GM. Drosophila genome organization: conserved and dynamic aspects. Annual Review of Genetics. 15: 219-64. PMID 6802066 DOI: 10.1146/  1
1981 Spradling AC, Mahowald AP. A chromosome inversion alters the pattern of specific DNA replication in Drosophila follicle cells. Cell. 27: 203-9. PMID 6799211 DOI: 10.1016/0092-8674(81)90374-3  1
1981 Spradling AC. The organization and amplification of two chromosomal domains containing Drosophila chorion genes. Cell. 27: 193-201. PMID 6799210 DOI: 10.1016/0092-8674(81)90373-1  1
1980 Spradling AC, Digan ME, Mahowald AP, Scott M, Craig EA. Two clusters of genes for major chorion proteins of Drosophila melanogaster. Cell. 19: 905-14. PMID 6769591 DOI: 10.1016/0092-8674(80)90082-3  1
1980 Spradling AC, Mahowald AP. Amplification of genes for chorion proteins during oogenesis in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 77: 1096-100. PMID 6767241  1
1979 Spradling AC, Waring GL, Mahowald AP. Drosophila bearing the ocelliless mutation underproduce two major chorion proteins both of which map near this gene. Cell. 16: 609-16. PMID 110455 DOI: 10.1016/0092-8674(79)90034-5  1
1979 Spradling AC, Mahowald AP. Identification and genetic localization of mRNAs from ovarian follicle cells of Drosophila melanogaster. Cell. 16: 589-98. PMID 110453 DOI: 10.1016/0092-8674(79)90032-1  1
1977 Spradling A, Pardue ML, Penman S. Messenger RNA in heat-shocked Drosophila cells. Journal of Molecular Biology. 109: 559-87. PMID 403287 DOI: 10.1016/S0022-2836(77)80091-0  1
1975 Spradling A, Singer RH, Lengyel J, Penman S. Methods with insect cells in suspension culture. I. Aedes albopictus. Methods in Cell Biology. 10: 185-94. PMID 1191393  1
1975 Spradling A. Calculation of mRNA lifetimes using ribosomal RNA labeling as a metabolic probe. Cell. 4: 139-40. PMID 1125976 DOI: 10.1016/0092-8674(75)90120-8  1
1975 Spradling A, Penman S, Pardue ML. Analysis of drosophila mRNA by in situ hybridization: sequences transcribed in normal and heat shocked cultured cells. Cell. 4: 395-404. PMID 1122559 DOI: 10.1016/0092-8674(75)90160-9  1
1975 Lengyel J, Spradling A, Penman S. Methods with insect cells in suspension culture. II. Drosophila melanogaster. Methods in Cell Biology. 10: 195-208. PMID 810640  1
1975 Spradling A, Hui H, Penman S. Two very different components of messenger RNA in an insect cell line. Cell. 4: 131-7. PMID 804997 DOI: 10.1016/0092-8674(75)90119-1  1
1974 Spradling A, Penman S, Campo MS, Bishop JO. Repetitious and unique sequences in the heterogeneous nuclear and cytoplasmic messenger RNA of mammalian and insect cells. Cell. 3: 23-30. PMID 4472286 DOI: 10.1016/0092-8674(74)90033-6  1
1974 Hirsch M, Spradling A, Penman S. The messenger-like poly(A)-containing RNA species from the mitochondria of mammals and insects Cell. 1: 31-35. DOI: 10.1016/0092-8674(74)90152-4  1
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