Andrew S. Rosenthal, Ph.D. - Publications

Affiliations: 
2010 Johns Hopkins University, Baltimore, MD 
Area:
Medicinal, Organic and Organometallic Chemistry

14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Song LN, Silva J, Koller A, Rosenthal A, Chen EI, Gelmann EP. The Tumor Suppressor NKX3.1 Is Targeted for Degradation by DYRK1B Kinase. Molecular Cancer Research : McR. 13: 913-22. PMID 25777618 DOI: 10.1158/1541-7786.MCR-14-0680  0.56
2014 Dexheimer TS, Rosenthal AS, Luci DK, Liang Q, Villamil MA, Chen J, Sun H, Kerns EH, Simeonov A, Jadhav A, Zhuang Z, Maloney DJ. Synthesis and structure-activity relationship studies of N-benzyl-2-phenylpyrimidin-4-amine derivatives as potent USP1/UAF1 deubiquitinase inhibitors with anticancer activity against nonsmall cell lung cancer. Journal of Medicinal Chemistry. 57: 8099-110. PMID 25229643 DOI: 10.1021/jm5010495  0.56
2014 Marchand C, Huang SY, Dexheimer TS, Lea WA, Mott BT, Chergui A, Naumova A, Stephen AG, Rosenthal AS, Rai G, Murai J, Gao R, Maloney DJ, Jadhav A, Jorgensen WL, et al. Biochemical assays for the discovery of TDP1 inhibitors. Molecular Cancer Therapeutics. 13: 2116-26. PMID 25024006 DOI: 10.1158/1535-7163.MCT-13-0952  0.56
2014 Liang Q, Dexheimer TS, Zhang P, Rosenthal AS, Villamil MA, You C, Zhang Q, Chen J, Ott CA, Sun H, Luci DK, Yuan B, Simeonov A, Jadhav A, Xiao H, et al. A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses. Nature Chemical Biology. 10: 298-304. PMID 24531842 DOI: 10.1038/nchembio.1455  0.56
2013 Rosenthal AS, Dexheimer TS, Gileadi O, Nguyen GH, Chu WK, Hickson ID, Jadhav A, Simeonov A, Maloney DJ. Synthesis and SAR studies of 5-(pyridin-4-yl)-1,3,4-thiadiazol-2-amine derivatives as potent inhibitors of Bloom helicase. Bioorganic & Medicinal Chemistry Letters. 23: 5660-6. PMID 24012121 DOI: 10.1016/j.bmcl.2013.08.025  0.56
2013 Nguyen GH, Dexheimer TS, Rosenthal AS, Chu WK, Singh DK, Mosedale G, Bachrati CZ, Schultz L, Sakurai M, Savitsky P, Abu M, McHugh PJ, Bohr VA, Harris CC, Jadhav A, et al. A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells. Chemistry & Biology. 20: 55-62. PMID 23352139 DOI: 10.1016/j.chembiol.2012.10.016  0.56
2011 He R, Mott BT, Rosenthal AS, Genna DT, Posner GH, Arav-Boger R. An artemisinin-derived dimer has highly potent anti-cytomegalovirus (CMV) and anti-cancer activities Plos One. 6. PMID 21904628 DOI: 10.1371/journal.pone.0024334  0.56
2011 Rosenthal AS, Tanega C, Shen M, Mott BT, Bougie JM, Nguyen DT, Misteli T, Auld DS, Maloney DJ, Thomas CJ. Potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk). Bioorganic & Medicinal Chemistry Letters. 21: 3152-8. PMID 21450467 DOI: 10.1016/j.bmcl.2011.02.114  0.56
2010 Arav-Boger R, He R, Chiou CJ, Liu J, Woodard L, Rosenthal A, Jones-Brando L, Forman M, Posner G. Artemisinin-derived dimers have greatly improved anti-cytomegalovirus activity compared to artemisinin monomers Plos One. 5. PMID 20442781 DOI: 10.1371/journal.pone.0010370  0.56
2009 Rosenthal AS, Chen X, Liu JO, West DC, Hergenrother PJ, Shapiro TA, Posner GH. Malaria-infected mice are cured by a single oral dose of new dimeric trioxane sulfones which are also selectively and powerfully cytotoxic to cancer cells. Journal of Medicinal Chemistry. 52: 1198-203. PMID 19186946 DOI: 10.1021/jm801484v  0.56
2009 Hartwig CL, Rosenthal AS, D'Angelo J, Griffin CE, Posner GH, Cooper RA. Accumulation of artemisinin trioxane derivatives within neutral lipids of Plasmodium falciparum malaria parasites is endoperoxide-dependent Biochemical Pharmacology. 77: 322-336. PMID 19022224 DOI: 10.1016/j.bcp.2008.10.015  0.56
2008 Posner GH, Chang W, Hess L, Woodard L, Sinishtaj S, Usera AR, Maio W, Rosenthal AS, Kalinda AS, D'Angelo JG, Petersen KS, Stohler R, Chollet J, Santo-Tomas J, Snyder C, et al. Malaria-infected mice are cured by oral administration of new artemisinin derivatives. Journal of Medicinal Chemistry. 51: 1035-42. PMID 18232653 DOI: 10.1021/jm701168h  0.56
2007 Posner GH, Paik IH, Chang W, Borstnik K, Sinishtaj S, Rosenthal AS, Shapiro TA. Malaria-infected mice are cured by a single dose of novel artemisinin derivatives Journal of Medicinal Chemistry. 50: 2516-2519. PMID 17439113 DOI: 10.1021/jm070149m  0.56
2006 Kim J, Li HB, Rosenthal AS, Sang D, Shapiro TA, Bachi MD, Posner GH. Ground state oxygen in synthesis of cyclic peroxides. Part 1: Benzo fused ketals Tetrahedron. 62: 4120-4127. DOI: 10.1016/j.tet.2006.02.008  0.56
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