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Karl E. Griswold, Ph.D. - Publications

Affiliations: 
2005 University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Antibody and Enzyme Engineering
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Zhao H, Brooks SA, Eszterhas S, Heim S, Li L, Xiong YQ, Fang Y, Kirsch JR, Verma D, Bailey-Kellogg C, Griswold KE. Globally deimmunized lysostaphin evades human immune surveillance and enables highly efficacious repeat dosing. Science Advances. 6. PMID 32917596 DOI: 10.1126/Sciadv.Abb9011  0.366
2018 Bricio-Moreno L, Sheridan VH, Goodhead I, Armstrong S, Wong JKL, Waters EM, Sarsby J, Panagiotou S, Dunn J, Chakraborty A, Fang Y, Griswold KE, Winstanley C, Fothergill JL, Kadioglu A, et al. Evolutionary trade-offs associated with loss of PmrB function in host-adapted Pseudomonas aeruginosa. Nature Communications. 9: 2635. PMID 29980663 DOI: 10.1038/S41467-018-04996-X  0.3
2017 Fang Y, Chu TH, Ackerman ME, Griswold KE. Going Native: direct high throughput screening of secreted full-length IgG antibodies against cell membrane proteins. Mabs. 0. PMID 28933630 DOI: 10.1080/19420862.2017.1381812  0.35
2017 Salvat RS, Verma D, Parker AS, Kirsch JR, Brooks SA, Bailey-Kellogg C, Griswold KE. Computationally optimized deimmunization libraries yield highly mutated enzymes with low immunogenicity and enhanced activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 28607051 DOI: 10.1073/Pnas.1621233114  0.416
2017 Choi Y, Verma D, Griswold KE, Bailey-Kellogg C. EpiSweep: Computationally Driven Reengineering of Therapeutic Proteins to Reduce Immunogenicity While Maintaining Function. Methods in Molecular Biology (Clifton, N.J.). 1529: 375-398. PMID 27914063 DOI: 10.1007/978-1-4939-6637-0_20  0.391
2016 Choi Y, Ndong C, Griswold KE, Bailey-Kellogg C. Computationally driven antibody engineering enables simultaneous humanization and thermostabilization. Protein Engineering, Design & Selection : Peds. PMID 27334453 DOI: 10.1093/Protein/Gzw024  0.303
2016 Griswold KE, Bailey-Kellogg C. Design and engineering of deimmunized biotherapeutics. Current Opinion in Structural Biology. 39: 79-88. PMID 27322891 DOI: 10.1016/J.Sbi.2016.06.003  0.345
2015 Blazanovic K, Zhao H, Choi Y, Li W, Salvat RS, Osipovitch DC, Fields J, Moise L, Berwin BL, Fiering SN, Bailey-Kellogg C, Griswold KE. Structure-based redesign of lysostaphin yields potent antistaphylococcal enzymes that evade immune cell surveillance. Molecular Therapy. Methods & Clinical Development. 2: 15021. PMID 26151066 DOI: 10.1038/Mtm.2015.21  0.421
2015 Zhao H, Verma D, Li W, Choi Y, Ndong C, Fiering SN, Bailey-Kellogg C, Griswold KE. Depletion of T cell epitopes in lysostaphin mitigates anti-drug antibody response and enhances antibacterial efficacy in vivo. Chemistry & Biology. 22: 629-39. PMID 26000749 DOI: 10.1016/J.Chembiol.2015.04.017  0.344
2015 Nemani KV, Ennis RC, Griswold KE, Gimi B. Magnetic nanoparticle hyperthermia induced cytosine deaminase expression in microencapsulated E. coli for enzyme-prodrug therapy. Journal of Biotechnology. 203: 32-40. PMID 25820125 DOI: 10.1016/J.Jbiotec.2015.03.008  0.399
2015 Osipovitch DC, Therrien S, Griswold KE. Discovery of novel S. aureus autolysins and molecular engineering to enhance bacteriolytic activity. Applied Microbiology and Biotechnology. 99: 6315-26. PMID 25690309 DOI: 10.1007/S00253-015-6443-2  0.385
2015 Osipovitch DC, Griswold KE. Fusion with a cell wall binding domain renders autolysin LytM a potent anti-Staphylococcus aureus agent. Fems Microbiology Letters. 362: 1-7. PMID 25670705 DOI: 10.1093/Femsle/Fnu035  0.383
2015 Salvat RS, Choi Y, Bishop A, Bailey-Kellogg C, Griswold KE. Protein deimmunization via structure-based design enables efficient epitope deletion at high mutational loads. Biotechnology and Bioengineering. 112: 1306-18. PMID 25655032 DOI: 10.1002/Bit.25554  0.385
2015 Dostal SM, Fang Y, Guerrette JC, Scanlon TC, Griswold KE. Genetically enhanced lysozyme evades a pathogen derived inhibitory protein. Acs Chemical Biology. 10: 1110-7. PMID 25607237 DOI: 10.1021/Cb500976Y  0.419
2015 Salvat RS, Parker AS, Choi Y, Bailey-Kellogg C, Griswold KE. Mapping the Pareto optimal design space for a functionally deimmunized biotherapeutic candidate. Plos Computational Biology. 11: e1003988. PMID 25568954 DOI: 10.1371/Journal.Pcbi.1003988  0.336
2014 Salvat RS, Parker AS, Guilliams A, Choi Y, Bailey-Kellogg C, Griswold KE. Computationally driven deletion of broadly distributed T cell epitopes in a biotherapeutic candidate. Cellular and Molecular Life Sciences : Cmls. 71: 4869-80. PMID 24880662 DOI: 10.1007/S00018-014-1652-X  0.384
2014 Griswold KE, Bement JL, Teneback CC, Scanlon TC, Wargo MJ, Leclair LW. Bioengineered lysozyme in combination therapies for Pseudomonas aeruginosa lung infections. Bioengineered. 5: 143-7. PMID 24637705 DOI: 10.4161/Bioe.28335  0.353
2014 Zhao H, Blazanovic K, Choi Y, Bailey-Kellogg C, Griswold KE. Gene and protein sequence optimization for high-level production of fully active and aglycosylated lysostaphin in Pichia pastoris. Applied and Environmental Microbiology. 80: 2746-53. PMID 24561590 DOI: 10.1128/Aem.03914-13  0.396
2014 Scanlon TC, Dostal SM, Griswold KE. A high-throughput screen for antibiotic drug discovery. Biotechnology and Bioengineering. 111: 232-43. PMID 23955804 DOI: 10.1002/Bit.25019  0.344
2013 Teneback CC, Scanlon TC, Wargo MJ, Bement JL, Griswold KE, Leclair LW. Bioengineered lysozyme reduces bacterial burden and inflammation in a murine model of mucoid Pseudomonas aeruginosa lung infection. Antimicrobial Agents and Chemotherapy. 57: 5559-64. PMID 23979752 DOI: 10.1128/Aac.00500-13  0.344
2013 Parker AS, Choi Y, Griswold KE, Bailey-Kellogg C. Structure-guided deimmunization of therapeutic proteins. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 20: 152-65. PMID 23384000 DOI: 10.1089/Cmb.2012.0251  0.381
2013 Choi Y, Griswold KE, Bailey-Kellogg C. Structure-based redesign of proteins for minimal T-cell epitope content. Journal of Computational Chemistry. 34: 879-91. PMID 23299435 DOI: 10.1002/Jcc.23213  0.366
2013 Lamppa JW, Tanyos SA, Griswold KE. Engineering Escherichia coli for soluble expression and single step purification of active human lysozyme. Journal of Biotechnology. 164: 1-8. PMID 23220215 DOI: 10.1016/J.Jbiotec.2012.11.007  0.404
2013 Lamppa JW, Griswold KE. Alginate lyase exhibits catalysis-independent biofilm dispersion and antibiotic synergy. Antimicrobial Agents and Chemotherapy. 57: 137-45. PMID 23070175 DOI: 10.1128/Aac.01789-12  0.344
2012 Osipovitch DC, Parker AS, Makokha CD, Desrosiers J, Kett WC, Moise L, Bailey-Kellogg C, Griswold KE. Design and analysis of immune-evading enzymes for ADEPT therapy. Protein Engineering, Design & Selection : Peds. 25: 613-23. PMID 22898588 DOI: 10.1093/Protein/Gzs044  0.419
2012 Funaro M, Nemani VK, Chen Z, Bhujwalla ZM, Griswold K, Gimi B. Abstract 5632: Immunoprotected, microencapsulated bacterial cytosine deaminase mediated conversion of 5-fluorocytosine to 5-fluorouracil Cancer Research. 72: 5632-5632. DOI: 10.1158/1538-7445.Am2012-5632  0.396
2011 Parker AS, Griswold KE, Bailey-Kellogg C. Optimization of combinatorial mutagenesis. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 18: 1743-56. PMID 21923411 DOI: 10.1089/Cmb.2011.0152  0.37
2011 Parker AS, Griswold KE, Bailey-Kellogg C. Optimization of therapeutic proteins to delete T-cell epitopes while maintaining beneficial residue interactions. Journal of Bioinformatics and Computational Biology. 9: 207-29. PMID 21523929 DOI: 10.1142/S0219720011005471  0.377
2011 Gill A, Scanlon TC, Osipovitch DC, Madden DR, Griswold KE. Crystal structure of a charge engineered human lysozyme having enhanced bactericidal activity. Plos One. 6: e16788. PMID 21408218 DOI: 10.1371/Journal.Pone.0016788  0.402
2011 Lamppa JW, Ackerman ME, Lai JI, Scanlon TC, Griswold KE. Genetically engineered alginate lyase-PEG conjugates exhibit enhanced catalytic function and reduced immunoreactivity. Plos One. 6: e17042. PMID 21340021 DOI: 10.1371/Journal.Pone.0017042  0.423
2010 Scanlon TC, Jewell HL, Gray EC, Griswold KE. The monoclonal myth. Bioengineered Bugs. 1: 225-8. PMID 21326931 DOI: 10.4161/Bbug.1.3.11724  0.353
2010 Scanlon TC, Teneback CC, Gill A, Bement JL, Weiner JA, Lamppa JW, Leclair LW, Griswold KE. Enhanced antimicrobial activity of engineered human lysozyme. Acs Chemical Biology. 5: 809-18. PMID 20604527 DOI: 10.1021/Cb1001119  0.384
2010 Parker AS, Zheng W, Griswold KE, Bailey-Kellogg C. Optimization algorithms for functional deimmunization of therapeutic proteins. Bmc Bioinformatics. 11: 180. PMID 20380721 DOI: 10.1186/1471-2105-11-180  0.397
2010 Zheng W, Griswold KE, Bailey-Kellogg C. Protein fragment swapping: a method for asymmetric, selective site-directed recombination. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 17: 459-75. PMID 20377457 DOI: 10.1089/Cmb.2009.0189  0.36
2009 Scanlon TC, Gray EC, Griswold KE. Quantifying and resolving multiple vector transformants in S. cerevisiae plasmid libraries. Bmc Biotechnology. 9: 95. PMID 19930565 DOI: 10.1186/1472-6750-9-95  0.364
2007 Zhu Y, Kekalo K, Ndong C, Huang YY, Shubitidze F, Griswold KE, Baker I, Zhang JXJ. Magnetic-Nanoparticle-Based Immunoassays-on-Chip: Materials Synthesis, Surface Functionalization, and Cancer Cell Screening Advanced Functional Materials. DOI: 10.1002/Adfm.201504176  0.305
2006 Griswold KE, Aiyappan NS, Iverson BL, Georgiou G. The evolution of catalytic efficiency and substrate promiscuity in human theta class 1-1 glutathione transferase. Journal of Molecular Biology. 364: 400-10. PMID 17011574 DOI: 10.1016/J.Jmb.2006.09.012  0.585
2005 Griswold KE, Kawarasaki Y, Ghoneim N, Benkovic SJ, Iverson BL, Georgiou G. Evolution of highly active enzymes by homology-independent recombination. Proceedings of the National Academy of Sciences of the United States of America. 102: 10082-7. PMID 16009931 DOI: 10.1073/Pnas.0504556102  0.587
2003 Kawarasaki Y, Griswold KE, Stevenson JD, Selzer T, Benkovic SJ, Iverson BL, Georgiou G. Enhanced crossover SCRATCHY: construction and high-throughput screening of a combinatorial library containing multiple non-homologous crossovers. Nucleic Acids Research. 31: e126. PMID 14576326 DOI: 10.1093/Nar/Gng126  0.548
2003 Griswold KE, Mahmood NA, Iverson BL, Georgiou G. Effects of codon usage versus putative 5'-mRNA structure on the expression of Fusarium solani cutinase in the Escherichia coli cytoplasm. Protein Expression and Purification. 27: 134-42. PMID 12509995 DOI: 10.1016/S1046-5928(02)00578-8  0.537
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