Mookda Pattarawarapan, Ph.D. - Related publications

2002 Texas A & M University, College Station, TX, United States 
medicinal chemistry, combinatorial chemistry, organic syntheses, asymmetric catalysis, and fluorescent dyes
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Shi JJ, Jia KH, Sun H, Gunosewoyo H, Yang F, Tang J, Luo J, Yu L. Synthesis and pharmacological evaluation of σ2 receptor ligands based on a 3-alkoxyisoxazole scaffold: potential antitumor effects against osteosarcoma. Chemmedchem. PMID 32964625 DOI: 10.1002/cmdc.202000461   
2020 Czopek A, Partyka A, Bucki A, Pawłowski M, Kołaczkowski M, Siwek A, Głuch-Lutwin M, Koczurkiewicz P, Pękala E, Jaromin A, Tyliszczak B, Wesołowska A, Zagórska A. Impact of N-Alkylamino Substituents on Serotonin Receptor (5-HTR) Affinity and Phosphodiesterase 10A (PDE10A) Inhibition of Isoindole-1,3-dione Derivatives. Molecules (Basel, Switzerland). 25. PMID 32854402 DOI: 10.3390/molecules25173868   
2020 Greenfield DA, Schmidt HR, Skiba MA, Mandler MD, Anderson JR, Sliz P, Kruse AC. Virtual Screening for Ligand Discovery at the σ Receptor. Acs Medicinal Chemistry Letters. 11: 1555-1561. PMID 32832023 DOI: 10.1021/acsmedchemlett.9b00314   
2020 Etkind SI, Vander Griend DA, Swager TM. Electroactive Anion Receptor with High Affinity for Arsenate. The Journal of Organic Chemistry. 85: 10050-10061. PMID 32790360 DOI: 10.1021/acs.joc.0c01206   
2020 Tsai SE, Li SM, Tseng CC, Chung CY, Zeng YH, Chieh Lin C, Fuh MT, Yang LC, Yang YC, Wong FF. Chlorotrimethylsilane promoted one-flask heterocyclic synthesis of 1,2,4-triazoles from nitrilimines: Modeling studies and bioactivity evaluation of LH-21 and Rimonabant analogues. Bioorganic Chemistry. 104: 104299. PMID 33002729 DOI: 10.1016/j.bioorg.2020.104299   
2020 Cerda-Cavieres C, Quiroz G, Iturriaga-Vásquez P, Rodríguez-Lavado J, Alarcón-Espósito J, Saitz C, Pessoa-Mahana CD, Chung H, Araya-Maturana R, Mella-Raipán J, Cabezas D, Ojeda-Gómez C, Reyes-Parada M, Pessoa-Mahana H. Synthesis, Docking, 3-D-Qsar, and Biological Assays of Novel Indole Derivatives Targeting Serotonin Transporter, Dopamine D2 Receptor, and Mao-A Enzyme: In the Pursuit for Potential Multitarget Directed Ligands. Molecules (Basel, Switzerland). 25. PMID 33050524 DOI: 10.3390/molecules25204614   
2020 Turky A, Sherbiny FF, Bayoumi AH, Ahmed HEA, Abulkhair HS. Novel 1,2,4-triazole derivatives: Design, synthesis, anticancer evaluation, molecular docking, and pharmacokinetic profiling studies. Archiv Der Pharmazie. e2000170. PMID 32893368 DOI: 10.1002/ardp.202000170   
2020 Cifani C, Micioni Di Bonaventura E, Botticelli L, Del Bello F, Giorgioni G, Pavletić P, Piergentili A, Quaglia W, Bonifazi A, Schepmann D, Wünsch B, Vistoli G, Micioni Di Bonaventura MV. Novel Highly Potent and Selective Sigma1 Receptor Antagonists Effectively Blocking the Binge Eating Episode in Female Rats. Acs Chemical Neuroscience. PMID 32886484 DOI: 10.1021/acschemneuro.0c00456   
2020 Vazquez-Rodriguez S, Vilar S, Kachler S, Klotz KN, Uriarte E, Borges F, Matos MJ. Adenosine Receptor Ligands: Coumarin-Chalcone Hybrids as Modulating Agents on the Activity of ARs. Molecules (Basel, Switzerland). 25. PMID 32961824 DOI: 10.3390/molecules25184306   
2020 Penthala NR, Shoeib A, Dachavaram SS, Cabanlong CV, Yang J, Zhan CG, Prather PL, Crooks PA. 7-Azaindolequinuclidinones (7-AIQD): A novel class of cannabinoid 1 (CB1) and cannabinoid 2 (CB2) receptor ligands. Bioorganic & Medicinal Chemistry Letters. 30: 127501. PMID 32882418 DOI: 10.1016/j.bmcl.2020.127501   
2020 Gunera J, Baker JG, van Hilten N, Rosenbaum DM, Kolb P. Structure-Based Discovery of Novel Ligands for the Orexin 2 Receptor. Journal of Medicinal Chemistry. PMID 32977721 DOI: 10.1021/acs.jmedchem.0c00964   
2020 Grosicki M, Adami M, Micheloni C, Głuch-Lutwin M, Siwek A, Latacz G, Łażewska D, Więcek M, Reiner D, Stark H, Chlopicki S, Kieć-Kononowicz K. Eosinophils adhesion assay as a tool for phenotypic drug screening - The pharmacology of 1,3,5 - Triazine and 1h-indole like derivatives against the human histamine H receptor. European Journal of Pharmacology. 173611. PMID 33017589 DOI: 10.1016/j.ejphar.2020.173611   
2020 Shan L, Cook KM, Haskins N, Omar B, Jiang Y, Garcia A, Koksal A, Oganesyan V, Rosenthal K, Wu H, Dall'Acqua WF, Damschroder MM. Long-acting antibody ligand mimetics for HER4-selective agonism. Scientific Reports. 10: 17257. PMID 33057063 DOI: 10.1038/s41598-020-74176-9   
2020 Hinnah K, Willems S, Morstein J, Heering J, Hartrampf F, Broichhagen J, Leippe P, Merk D, Trauner D. Photohormones Enable Optical Control of the Peroxisome Proliferator-Activated Receptor Gamma (PPAR). Journal of Medicinal Chemistry. PMID 32886507 DOI: 10.1021/acs.jmedchem.0c00654   
2020 Han X, Nieman MT. The domino effect triggered by the tethered ligand of the protease activated receptors. Thrombosis Research. 196: 87-98. PMID 32853981 DOI: 10.1016/j.thromres.2020.08.004   
2020 de Luna Martins D, Borges AA, E Silva NADA, Faria JV, Hoelz LVB, de Souza HVCM, Bello ML, Boechat N, Ferreira VF, Faria RX. P2X7 receptor inhibition by 2-amino-3-aryl-1,4-naphthoquinones. Bioorganic Chemistry. 104: 104278. PMID 33010623 DOI: 10.1016/j.bioorg.2020.104278   
2020 Elisi GM, Bedini A, Scalvini L, Carmi C, Bartolucci S, Lucini V, Scaglione F, Mor M, Rivara S, Spadoni G. Chiral Recognition of Flexible Melatonin Receptor Ligands Induced by Conformational Equilibria. Molecules (Basel, Switzerland). 25. PMID 32899888 DOI: 10.3390/molecules25184057   
2020 Banerjee S, Norman DD, Deng S, Fakayode SO, Lee SC, Parrill AL, Li W, Miller DD, Tigyi GJ. Molecular modelling guided design, synthesis and QSAR analysis of new small molecule non-lipid autotaxin inhibitors. Bioorganic Chemistry. 103: 104188. PMID 32890995 DOI: 10.1016/j.bioorg.2020.104188   
2020 Hodolic M, Wu WY, Zhao Z, Yu F, Virgolini I, Wang F. Safety and tolerability of Ga-NT-20.3, a radiopharmaceutical for targeting neurotensin receptors, in patients with pancreatic ductal adenocarcinoma: the first in-human use. European Journal of Nuclear Medicine and Molecular Imaging. PMID 33006657 DOI: 10.1007/s00259-020-05045-w   
2020 Xie XY, Li YY, Ma WH, Chen AF, Sun YT, Lee JY, Riad A, Xu DH, Mach RH, Huang YS. Synthesis, binding, and functional properties of tetrahydroisoquinolino-2-alkyl phenones as selective σR/TMEM97 ligands. European Journal of Medicinal Chemistry. 209: 112906. PMID 33049607 DOI: 10.1016/j.ejmech.2020.112906   
2020 Velcicky J, Wilcken R, Cotesta S, Janser P, Schlapbach A, Wagner T, Piechon P, Villard F, Bouhelal R, Piller F, Harlfinger S, Stringer R, Fehlmann D, Kaupmann K, Littlewood-Evans A, et al. Discovery and Optimization of Novel SUCNR1 Inhibitors: Design of Zwitterionic Derivatives with a Salt Bridge for the Improvement of Oral Exposure. Journal of Medicinal Chemistry. PMID 32856916 DOI: 10.1021/acs.jmedchem.0c01020   
2020 Lokhande KB, Ballav S, Yadav RS, Swamy KV, Basu S. Probing intermolecular interactions and binding stability of kaempferol, quercetin and resveratrol derivatives with PPAR-γ: docking, molecular dynamics and MM/GBSA approach to reveal potent PPAR- γ agonist against cancer. Journal of Biomolecular Structure & Dynamics. 1-11. PMID 32954977 DOI: 10.1080/07391102.2020.1820380   
2020 Boutin JA, Witt-Enderby PA, Sotriffer C, Zlotos DP. Melatonin receptor ligands: A pharmaco-chemical perspective. Journal of Pineal Research. 69: e12672. PMID 32531076 DOI: 10.1111/jpi.12672   
2020 Che J, Feng R, Gao J, Yu H, Weng Q, He Q, Dong X, Wu J, Yang B. Evaluation of Artificial Intelligence in Participating Structure-Based Virtual Screening for Identifying Novel Interleukin-1 Receptor Associated Kinase-1 Inhibitors. Frontiers in Oncology. 10: 1769. PMID 33014870 DOI: 10.3389/fonc.2020.01769   
2020 Peri SSS, Sabnani MK, Raza MU, Urquhart EL, Ghaffari S, Lee J, Kim M, Weidanz JA, Alexandrakis G. Quantification of Low Affinity Binding Interactions between Natural Killer Cell Inhibitory Receptors and Targeting Ligands with a Self-Induced Back-Action Actuated Nanopore Electrophoresis (SANE) Sensor. Nanotechnology. PMID 33027774 DOI: 10.1088/1361-6528/abbf26   
2020 Ott J, Spilhaug MM, Maschauer S, Rafique W, Jakobsson JE, Hartvig K, Hübner H, Gmeiner P, Prante O, Riss PJ. Pharmacological Characterization of Low-to-Moderate Affinity Opioid Receptor Agonists and Brain Imaging with F-Labeled Derivatives in Rats. Journal of Medicinal Chemistry. 63: 9484-9499. PMID 32787100 DOI: 10.1021/acs.jmedchem.0c00683   
2020 Pieterse L, van der Walt MM, Terre'Blanche G. C2-substituted quinazolinone derivatives exhibit A and/or A adenosine receptor affinities in the low micromolar range. Bioorganic & Medicinal Chemistry Letters. 30: 127274. PMID 32631506 DOI: 10.1016/j.bmcl.2020.127274   
2020 Borthwick AD, Goncalves MB, Corcoran JPT. Recent advances in the design of RAR α and RAR β agonists as orally bioavailable drugs. A review. Bioorganic & Medicinal Chemistry. 28: 115664. PMID 33069074 DOI: 10.1016/j.bmc.2020.115664   
2020 Fernandes RA, Su L, Nishiga Y, Ren J, Bhuiyan AM, Cheng N, Kuo CJ, Picton LK, Ohtsuki S, Majzner RG, Rietberg SP, Mackall CL, Yin Q, Ali LR, Yang X, et al. Immune receptor inhibition through enforced phosphatase recruitment. Nature. PMID 33087934 DOI: 10.1038/s41586-020-2851-2   
2020 Pismataro MC, Horenstein NA, Stokes C, Quadri M, De Amici M, Papke RL, Dallanoce C. Design, synthesis, and electrophysiological evaluation of NS6740 derivatives: Exploration of the structure-activity relationship for alpha7 nicotinic acetylcholine receptor silent activation. European Journal of Medicinal Chemistry. 205: 112669. PMID 32810771 DOI: 10.1016/j.ejmech.2020.112669   
2020 Zhao Y, Gao L, Li H, Sun P, Meng F, Zhang Y, Xie Y, Sun B, Zhou S, Ma Y, Xiong L, Yang N, Li Y, Li ZM. Synthesis, Insecticidal Activities and Structure-Activity Relationship of Phenylpyrazole Derivatives Containing Fluoro-substituted Benzene Moiety. Journal of Agricultural and Food Chemistry. PMID 32926621 DOI: 10.1021/acs.jafc.9b08090   
2020 Maurya AK, Mishra N. validation of coumarin derivatives as potential inhibitors against Main Protease, NSP10/NSP16-Methyltransferase, Phosphatase and Endoribonuclease of SARS CoV-2. Journal of Biomolecular Structure & Dynamics. 1-16. PMID 32835632 DOI: 10.1080/07391102.2020.1808075   
2020 Ricart-Ortega M, Berizzi AE, Pereira V, Malhaire F, Catena J, Font J, Gómez-Santacana X, Muñoz L, Zussy C, Serra C, Rovira X, Goudet C, Llebaria A. Mechanistic Insights into Light-Driven Allosteric Control of GPCR Biological Activity. Acs Pharmacology & Translational Science. 3: 883-895. PMID 33073188 DOI: 10.1021/acsptsci.0c00054   
2020 Xin M, Sun J, Huang W, Tang F, Liu Z, Jin Q, Wang J. Design and synthesis of novel phthalazinone derivatives as potent poly(ADP-ribose)polymerase 1 inhibitors. Future Medicinal Chemistry. PMID 33012191 DOI: 10.4155/fmc-2020-0009   
2020 Sen D, Debnath P, Debnath B, Bhaumik S, Debnath S. Identification of potential inhibitors of SARS-CoV-2 main protease and spike receptor from 10 important spices through structure-based virtual screening and molecular dynamic study. Journal of Biomolecular Structure & Dynamics. 1-22. PMID 32948116 DOI: 10.1080/07391102.2020.1819883   
2020 da Rocha-Azevedo B, Lee S, Dasgupta A, Vega AR, de Oliveira LR, Kim T, Kittisopikul M, Malik ZA, Jaqaman K. Heterogeneity in VEGF Receptor-2 Mobility and Organization on the Endothelial Cell Surface Leads to Diverse Models of Activation by VEGF. Cell Reports. 32: 108187. PMID 32997988 DOI: 10.1016/j.celrep.2020.108187   
2020 Basuli F, Zhang X, Phelps TE, Jagoda EM, Choyke PL, Swenson RE. Automated Synthesis of Fluorine-18 Labeled CXCR4 Ligand via the Conjugation with Nicotinic Acid -Hydroxysuccinimide Ester (6-[F]SFPy). Molecules (Basel, Switzerland). 25. PMID 32867358 DOI: 10.3390/molecules25173924   
2020 Sun J, Shen D, Gao Y, Zheng Y, Zhao L, Maa M, Liu H, Chen X. Down-Regulation of USP8 Suppresses HER-3 Positive Gastric Cancer Cells Proliferation. Oncotargets and Therapy. 13: 7973-7984. PMID 32848421 DOI: 10.2147/OTT.S264108   
2020 Szczepańska K, Kincses A, Vincze K, Szymańska E, Latacz G, Kuder KJ, Stark H, Spengler G, Handzlik J, Kieć-Kononowicz K. N-Substituted piperazine derivatives as potential multitarget agents acting on histamine H receptor and cancer resistance proteins. Bioorganic & Medicinal Chemistry Letters. 30: 127522. PMID 32871268 DOI: 10.1016/j.bmcl.2020.127522   
2020 Emerich BL, Ferreira RCM, Machado-de-Avila RA, Resende JM, Duarte IDG, de Lima ME. PnAn13, an antinociceptive synthetic peptide inspired in the toxin PnTx4(6-1) (δ-Ctenitoxin-Pn1a). Toxicon: X. 7: 100045. PMID 32875290 DOI: 10.1016/j.toxcx.2020.100045   
2020 Szőke É, Bálint M, Hetényi C, Markovics A, Elekes K, Pozsgai G, Szűts T, Kéri G, Őrfi L, Sándor Z, Szolcsányi J, Pintér E, Helyes Z. Small molecule somatostatin receptor subtype 4 (sst) agonists are novel anti-inflammatory and analgesic drug candidates. Neuropharmacology. 178: 108198. PMID 32739276 DOI: 10.1016/j.neuropharm.2020.108198   
2020 Vunnam N, Szymonski S, Hirsova P, Gores G, Sachs JN, Hackel BJ. Noncompetitive allosteric antagonism of death receptor 5 by a synthetic affibody ligand. Biochemistry. PMID 32941010 DOI: 10.1021/acs.biochem.0c00529   
2020 Hayatshahi HS, Liu J. Filtering out Low-Affinity Bitropic Ligands for Dopamine Receptors Based on Ligand Conformation. Acs Chemical Neuroscience. 11: 2523-2527. PMID 32786308 DOI: 10.1021/acschemneuro.0c00263   
2020 Hayatshahi HS, Liu J. Filtering out Low-Affinity Bitropic Ligands for Dopamine Receptors Based on Ligand Conformation. Acs Chemical Neuroscience. 11: 2523-2527. PMID 32786308 DOI: 10.1021/acschemneuro.0c00263   
2020 Scammells PJ, Jörg M, Khajehali E, van der Westhuizen ET, Choy KHC, Shackleford D, Tobin AB, Sexton PM, Valant C, Capuano B, Christopoulos A. Development of Novel 4-Arylpyridin-2-one and 6-Arylpyrimidin-4-one Positive Allosteric Modulators of the M1 Muscarinic Acetylcholine Receptor. Chemmedchem. PMID 32851779 DOI: 10.1002/cmdc.202000540   
2020 He Y, Hwang DJ, Ponnusamy S, Thiyagarajan T, Mohler ML, Narayanan R, Miller DD. Pyrazol-1-yl-propanamides as SARD and Pan-Antagonists for the Treatment of Enzalutamide-Resistant Prostate Cancer. Journal of Medicinal Chemistry. PMID 33095584 DOI: 10.1021/acs.jmedchem.0c00943   
2020 Abdelrheem DA, Ahmed SA, Abd El-Mageed HR, Mohamed HS, Rahman AA, Elsayed KNM, Ahmed SA. The inhibitory effect of some natural bioactive compounds against SARS-CoV-2 main protease: insights from molecular docking analysis and molecular dynamic simulation. Journal of Environmental Science and Health. Part a, Toxic/Hazardous Substances & Environmental Engineering. 1-14. PMID 32998618 DOI: 10.1080/10934529.2020.1826192   
2020 Makhaeva GF, Kovaleva NV, Boltneva NP, Lushchekina SV, Astakhova TY, Rudakova EV, Proshin AN, Serkov IV, Radchenko EV, Palyulin VA, Bachurin SO, Richardson RJ. New Hybrids of 4-Amino-2,3-polymethylene-quinoline and -Tolylsulfonamide as Dual Inhibitors of Acetyl- and Butyrylcholinesterase and Potential Multifunctional Agents for Alzheimer's Disease Treatment. Molecules (Basel, Switzerland). 25. PMID 32867324 DOI: 10.3390/molecules25173915   
2020 Sarkar A, Adamska-Bartlomiejczyk A, Piekielna-Ciesielska J, Wtorek K, Kluczyk A, Borics A, Janecka A. Design, Synthesis and Functional Analysis of Cyclic Opioid Peptides with Dmt-Tic Pharmacophore. Molecules (Basel, Switzerland). 25. PMID 32957550 DOI: 10.3390/molecules25184260   
2020 Yang JF, Williams AH, Penthala NR, Prather PL, Crooks PA, Zhan CG. Binding Modes and Selectivity of Cannabinoid 1 (CB1) and Cannabinoid 2 (CB2) Receptor Ligands. Acs Chemical Neuroscience. PMID 32997485 DOI: 10.1021/acschemneuro.0c00551