Christopher M. Rath, Ph.D. - Publications

Affiliations: 
2011 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
cryptophycin anticancer drugs

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Rateb ME, Zhai Y, Ehrner E, Rath CM, Wang X, Tabudravu J, Ebel R, Bibb M, Kyeremeh K, Dorrestein PC, Hong K, Jaspars M, Deng H. Legonaridin, a new member of linaridin RiPP from a Ghanaian Streptomyces isolate. Organic & Biomolecular Chemistry. 13: 9585-92. PMID 26256511 DOI: 10.1039/C5Ob01269D  0.8
2015 Bouslimani A, Porto C, Rath CM, Wang M, Guo Y, Gonzalez A, Berg-Lyon D, Ackermann G, Moeller Christensen GJ, Nakatsuji T, Zhang L, Borkowski AW, Meehan MJ, Dorrestein K, Gallo RL, et al. Molecular cartography of the human skin surface in 3D. Proceedings of the National Academy of Sciences of the United States of America. 112: E2120-9. PMID 25825778 DOI: 10.1073/Pnas.1424409112  0.8
2013 Yang JY, Sanchez LM, Rath CM, Liu X, Boudreau PD, Bruns N, Glukhov E, Wodtke A, de Felicio R, Fenner A, Wong WR, Linington RG, Zhang L, Debonsi HM, Gerwick WH, et al. Molecular networking as a dereplication strategy. Journal of Natural Products. 76: 1686-99. PMID 24025162 DOI: 10.1021/Np400413S  0.8
2013 Hansen DA, Rath CM, Eisman EB, Narayan AR, Kittendorf JD, Mortison JD, Yoon YJ, Sherman DH. Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin. Journal of the American Chemical Society. 135: 11232-8. PMID 23866020 DOI: 10.1021/Ja404134F  0.8
2013 Rath CM, Yang JY, Alexandrov T, Dorrestein PC. Data-independent microbial metabolomics with ambient ionization mass spectrometry. Journal of the American Society For Mass Spectrometry. 24: 1167-76. PMID 23568029 DOI: 10.1007/S13361-013-0608-Y  0.8
2012 Rath CM, Alexandrov T, Higginbottom SK, Song J, Milla ME, Fischbach MA, Sonnenburg JL, Dorrestein PC. Molecular analysis of model gut microbiotas by imaging mass spectrometry and nanodesorption electrospray ionization reveals dietary metabolite transformations. Analytical Chemistry. 84: 9259-67. PMID 23009651 DOI: 10.1021/Ac302039U  0.8
2012 Chemler JA, Buchholz TJ, Geders TW, Akey DL, Rath CM, Chlipala GE, Smith JL, Sherman DH. Biochemical and structural characterization of germicidin synthase: analysis of a type III polyketide synthase that employs acyl-ACP as a starter unit donor. Journal of the American Chemical Society. 134: 7359-66. PMID 22480290 DOI: 10.1021/Ja2112228  0.8
2012 Rath CM, Dorrestein PC. The bacterial chemical repertoire mediates metabolic exchange within gut microbiomes. Current Opinion in Microbiology. 15: 147-54. PMID 22209085 DOI: 10.1016/J.Mib.2011.12.009  0.8
2011 Bonnett SA, Rath CM, Shareef AR, Joels JR, Chemler JA, Håkansson K, Reynolds K, Sherman DH. Acyl-CoA subunit selectivity in the pikromycin polyketide synthase PikAIV: steady-state kinetics and active-site occupancy analysis by FTICR-MS. Chemistry & Biology. 18: 1075-81. PMID 21944746 DOI: 10.1016/J.Chembiol.2011.07.016  0.8
2011 Rath CM, Janto B, Earl J, Ahmed A, Hu FZ, Hiller L, Dahlgren M, Kreft R, Yu F, Wolff JJ, Kweon HK, Christiansen MA, Håkansson K, Williams RM, Ehrlich GD, et al. Meta-omic characterization of the marine invertebrate microbial consortium that produces the chemotherapeutic natural product ET-743. Acs Chemical Biology. 6: 1244-56. PMID 21875091 DOI: 10.1021/Cb200244T  0.8
2011 Ding Y, Rath CM, Bolduc KL, Håkansson K, Sherman DH. Chemoenzymatic synthesis of cryptophycin anticancer agents by an ester bond-forming non-ribosomal peptide synthetase module. Journal of the American Chemical Society. 133: 14492-5. PMID 21823639 DOI: 10.1021/Ja204716F  0.8
2010 Buchholz TJ, Rath CM, Lopanik NB, Gardner NP, Håkansson K, Sherman DH. Polyketide β-branching in bryostatin biosynthesis: identification of surrogate acetyl-ACP donors for BryR, an HMG-ACP synthase. Chemistry & Biology. 17: 1092-100. PMID 21035732 DOI: 10.1016/J.Chembiol.2010.08.008  0.8
2010 Scaglione JB, Akey DL, Sullivan R, Kittendorf JD, Rath CM, Kim ES, Smith JL, Sherman DH. Biochemical and structural characterization of the tautomycetin thioesterase: analysis of a stereoselective polyketide hydrolase. Angewandte Chemie (International Ed. in English). 49: 5726-30. PMID 20623733 DOI: 10.1002/Anie.201000032  0.8
2010 Rath CM, Scaglione JB, Kittendorf JD, Sherman DH. NRPS/PKS hybrid enzymes and their natural products Comprehensive Natural Products Ii: Chemistry and Biology. 1: 453-492.  0.8
2008 Lopanik NB, Shields JA, Buchholz TJ, Rath CM, Hothersall J, Haygood MG, Håkansson K, Thomas CM, Sherman DH. In vivo and in vitro trans-acylation by BryP, the putative bryostatin pathway acyltransferase derived from an uncultured marine symbiont. Chemistry & Biology. 15: 1175-86. PMID 19022178 DOI: 10.1016/J.Chembiol.2008.09.013  0.8
2008 Pfleger BF, Kim Y, Nusca TD, Maltseva N, Lee JY, Rath CM, Scaglione JB, Janes BK, Anderson EC, Bergman NH, Hanna PC, Joachimiak A, Sherman DH. Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 105: 17133-8. PMID 18955706 DOI: 10.1073/Pnas.0808118105  0.8
2003 Amagata T, Rath C, Rigot JF, Tarlov N, Tenney K, Valeriote FA, Crews P. Structures and cytotoxic properties of trichoverroids and their macrolide analogues produced by saltwater culture of Myrothecium verrucaria Journal of Medicinal Chemistry. 46: 4342-4350. PMID 13678412 DOI: 10.1021/Jm030090T  0.8
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