Bryant M. Wood, Ph.D. - Publications

Affiliations: 
2010 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
structure/function relationships for enzyme-catalyzed reactions

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Cho K, Evans BS, Wood BM, Kumar R, Erb TJ, Warlick BP, Gerlt JA, Sweedler JV. Integration of untargeted metabolomics with transcriptomics reveals active metabolic pathways. Metabolomics : Official Journal of the Metabolomic Society. 2014. PMID 25705145 DOI: 10.1007/S11306-014-0713-3  0.56
2014 Kumar R, Zhao S, Vetting MW, Wood BM, Sakai A, Cho K, Solbiati J, Almo SC, Sweedler JV, Jacobson MP, Gerlt JA, Cronan JE. Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine. Mbio. 5: e00933-13. PMID 24520058 DOI: 10.1128/Mbio.00933-13  0.56
2013 Zhao S, Kumar R, Sakai A, Vetting MW, Wood BM, Brown S, Bonanno JB, Hillerich BS, Seidel RD, Babbitt PC, Almo SC, Sweedler JV, Gerlt JA, Cronan JE, Jacobson MP. Discovery of new enzymes and metabolic pathways by using structure and genome context. Nature. 502: 698-702. PMID 24056934 DOI: 10.1038/Nature12576  0.56
2012 Erb TJ, Evans BS, Cho K, Warlick BP, Sriram J, Wood BM, Imker HJ, Sweedler JV, Tabita FR, Gerlt JA. A RubisCO-like protein links SAM metabolism with isoprenoid biosynthesis. Nature Chemical Biology. 8: 926-32. PMID 23042035 DOI: 10.1038/Nchembio.1087  0.56
2012 Desai BJ, Wood BM, Fedorov AA, Fedorov EV, Goryanova B, Amyes TL, Richard JP, Almo SC, Gerlt JA. Conformational changes in orotidine 5′-monophosphate decarboxylase: A structure-based explanation for how the 5′-phosphate group activates the enzyme Biochemistry. 51: 8665-8678. PMID 23030629 DOI: 10.1021/Bi301188K  0.56
2012 Tsang WY, Wood BM, Wong FM, Wu W, Gerlt JA, Amyes TL, Richard JP. Proton transfer from C-6 of uridine 5′-monophosphate catalyzed by orotidine 5′-monophosphate decarboxylase: Formation and stability of a vinyl carbanion intermediate and the effect of a 5-fluoro substituent Journal of the American Chemical Society. 134: 14580-14594. PMID 22812629 DOI: 10.1021/Ja3058474  0.56
2012 Amyes TL, Ming SA, Goldman LM, Wood BM, Desai BJ, Gerlt JA, Richard JP. Orotidine 5′-monophosphate decarboxylase: Transition state stabilization from remote protein-phosphodianion interactions Biochemistry. 51: 4630-4632. PMID 22620855 DOI: 10.1021/Bi300585E  0.56
2010 Toth K, Amyes TL, Wood BM, Chan K, Gerlt JA, Richard JP. Product deuterium isotope effects for orotidine 5'-monophosphate decarboxylase: effect of changing substrate and enzyme structure on the partitioning of the vinyl carbanion reaction intermediate. Journal of the American Chemical Society. 132: 7018-24. PMID 20441167 DOI: 10.1021/Ja102408K  0.56
2010 Wood BM, Amyes TL, Fedorov AA, Fedorov EV, Shabila A, Almo SC, Richard JP, Gerlt JA. Conformational changes in orotidine 5′-monophosphate decarboxylase: "remote" residues that stabilize the active conformation Biochemistry. 49: 3514-3516. PMID 20369850 DOI: 10.1021/Bi100443A  0.56
2010 Barnett SA, Amyes TL, Wood BM, Gerlt JA, Richard JP. Activation of R235A mutant orotidine 5′-monophosphate decarboxylase by the guanidinium cation: Effective molarity of the cationic side chain of Arg-235 Biochemistry. 49: 824-826. PMID 20050635 DOI: 10.1021/Bi902174Q  0.56
2009 Toth K, Amyes TL, Wood BM, Chan KK, Gerlt JA, Richard JP. An examination of the relationship between active site loop size and thermodynamic activation parameters for orotidine 5'-monophosphate decarboxylase from mesophilic and thermophilic organisms. Biochemistry. 48: 8006-13. PMID 19618917 DOI: 10.1021/Bi901064K  0.56
2009 Chan KK, Wood BM, Fedorov AA, Fedorov EV, Imker HJ, Amyes TL, Richard JP, Almo SC, Gerlt JA. Mechanism of the orotidine 5′-monophosphate decarboxylase-catalyzed reaction: Evidence for substrate destabilization Biochemistry. 48: 5518-5531. PMID 19435314 DOI: 10.1021/Bi900623R  0.56
2009 Wood BM, Chan KK, Amyes TL, Richard JP, Gerlt JA. Mechanism of the orotidine 5′-monophosphate decarboxylase-catalyzed reaction: Effect of solvent viscosity on kinetic constants Biochemistry. 48: 5510-5517. PMID 19435313 DOI: 10.1021/Bi9006226  0.56
2008 Barnett SA, Amyes TL, Wood BM, Gerlt JA, Richard JP. Dissecting the total transition state stabilization provided by amino acid side chains at orotidine 5′-monophosphate decarboxylase: A two-part substrate approach Biochemistry. 47: 7785-7787. PMID 18598058 DOI: 10.1021/Bi800939K  0.56
2008 Amyes TL, Wood BM, Chan K, Gerlt JA, Richard JP. Formation and stability of a vinyl carbanion at the active site of orotidine 5′-monophosphate decarboxylase: pKa of the C-6 proton of enzyme-bound UMP Journal of the American Chemical Society. 130: 1574-1575. PMID 18186641 DOI: 10.1021/Ja710384T  0.56
2007 Toth K, Amyes TL, Wood BM, Chan K, Gerlt JA, Richard JP. Product deuterium isotope effect for orotidine 5'-monophosphate decarboxylase: evidence for the existence of a short-lived carbanion intermediate. Journal of the American Chemical Society. 129: 12946-7. PMID 17918849 DOI: 10.1021/Ja076222F  0.56
2006 Yew WS, Fedorov AA, Fedorov EV, Wood BM, Almo SC, Gerlt JA. Evolution of enzymatic activities in the enolase superfamily: D-tartrate dehydratase from Bradyrhizobium japonicum Biochemistry. 45: 14598-14608. PMID 17144653 DOI: 10.1021/Bi061688G  0.56
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