Jay Kalin, Ph.D. - Publications

2012 Medicinal Chemistry University of Illinois at Chicago, Chicago, IL, United States 
medicinal chemistry

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Anastas JN, Zee BM, Kalin JH, Kim M, Guo R, Alexandrescu S, Blanco MA, Giera S, Gillespie SM, Das J, Wu M, Nocco S, Bonal DM, Nguyen QD, Suva ML, et al. Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG. Cancer Cell. PMID 31631026 DOI: 10.1016/j.ccell.2019.09.005  0.48
2018 Wu M, Hayward D, Kalin JH, Song Y, Schwabe JW, Cole PA. Lysine-14 acetylation of histone H3 in chromatin confers resistance to the deacetylase and demethylase activities of an epigenetic silencing complex. Elife. 7. PMID 29869982 DOI: 10.7554/eLife.37231  0.48
2018 Kalin JH, Wu M, Gomez AV, Song Y, Das J, Hayward D, Adejola N, Wu M, Panova I, Chung HJ, Kim E, Roberts HJ, Roberts JM, Prusevich P, Jeliazkov JR, et al. Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors. Nature Communications. 9: 53. PMID 29302039 DOI: 10.1038/s41467-017-02242-4  0.48
2016 Hsiao PY, Kalin J, Sun IH, Amin M, Lo YC, Chiang MJ, Giddens J, Sysa-Shah P, Gabrielson K, Wang LX, Powell J, Cole PA. An Fc-Small Molecule Conjugate for Targeted Inhibition of the Adenosine 2A Receptor. Chembiochem : a European Journal of Chemical Biology. PMID 27432157 DOI: 10.1002/cbic.201600337  0.72
2015 Lu S, Zhang Y, Kalin JH, Cai L, Kozikowski AP, Pike VW. Exploration of the labeling of [(11) C]tubastatin A at the hydroxamic acid site with [(11) C]carbon monoxide. Journal of Labelled Compounds & Radiopharmaceuticals. PMID 26647018 DOI: 10.1002/jlcr.3360  0.72
2015 Shen S, Benoy V, Bergman JA, Kalin JH, Frojuello M, Vistoli G, Haeck W, Van Den Bosch L, Kozikowski AP. Bicyclic-Capped Histone Deacetylase 6 Inhibitors with Improved Activity in a Model of Axonal Charcot-Marie-Tooth Disease. Acs Chemical Neuroscience. PMID 26599234 DOI: 10.1021/acschemneuro.5b00286  0.72
2014 Cheng F, Lienlaf M, Wang HW, Perez-Villarroel P, Lee C, Woan K, Rock-Klotz J, Sahakian E, Woods D, Pinilla-Ibarz J, Kalin J, Tao J, Hancock W, Kozikowski A, Seto E, et al. A novel role for histone deacetylase 6 in the regulation of the tolerogenic STAT3/IL-10 pathway in APCs. Journal of Immunology (Baltimore, Md. : 1950). 193: 2850-62. PMID 25108026 DOI: 10.4049/jimmunol.1302778  0.72
2014 Prusevich P, Kalin JH, Ming SA, Basso M, Givens J, Li X, Hu J, Taylor MS, Cieniewicz AM, Hsiao PY, Huang R, Roberson H, Adejola N, Avery LB, Casero RA, et al. A selective phenelzine analogue inhibitor of histone demethylase LSD1. Acs Chemical Biology. 9: 1284-93. PMID 24707965 DOI: 10.1021/cb500018s  0.72
2014 Selenica ML, Benner L, Housley SB, Manchec B, Lee DC, Nash KR, Kalin J, Bergman JA, Kozikowski A, Gordon MN, Morgan D. Histone deacetylase 6 inhibition improves memory and reduces total tau levels in a mouse model of tau deposition. Alzheimer's Research & Therapy. 6: 12. PMID 24576665 DOI: 10.1186/alzrt241  0.72
2014 Chiang MJ, Holbert MA, Kalin JH, Ahn YH, Giddens J, Amin MN, Taylor MS, Collins SL, Chan-Li Y, Waickman A, Hsiao PY, Bolduc D, Leahy DJ, Horton MR, Wang LX, et al. An Fc domain protein-small molecule conjugate as an enhanced immunomodulator. Journal of the American Chemical Society. 136: 3370-3. PMID 24533830 DOI: 10.1021/ja5006674  0.72
2013 Kalin JH, Bergman JA. Development and therapeutic implications of selective histone deacetylase 6 inhibitors. Journal of Medicinal Chemistry. 56: 6297-313. PMID 23627282 DOI: 10.1021/jm4001659  0.72
2013 Budke B, Kalin JH, Pawlowski M, Zelivianskaia AS, Wu M, Kozikowski AP, Connell PP. An optimized RAD51 inhibitor that disrupts homologous recombination without requiring michael acceptor reactivity Journal of Medicinal Chemistry. 56: 254-263. PMID 23231413 DOI: 10.1021/jm301565b  0.72
2012 Budke B, Logan HL, Kalin JH, Zelivianskaia AS, Cameron McGuire W, Miller LL, Stark JM, Kozikowski AP, Bishop DK, Connell PP. RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cells. Nucleic Acids Research. 40: 7347-57. PMID 22573178 DOI: 10.1093/nar/gks353  0.72
2012 Kalin JH, Zhang H, Gaudrel-Grosay S, Vistoli G, Kozikowski AP. Chiral Mercaptoacetamides Display Enantioselective Inhibition of Histone Deacetylase6 and Exhibit Neuroprotection in Cortical Neuron Models of Oxidative Stress Chemmedchem. 7: 425-439. PMID 22234885 DOI: 10.1002/cmdc.201100522  0.72
2012 Kalin JH, Butler KV, Akimova T, Hancock WW, Kozikowski AP. Second-generation histone deacetylase 6 inhibitors enhance the immunosuppressive effects of Foxp3+ T-regulatory cells Journal of Medicinal Chemistry. 55: 639-651. PMID 22165909 DOI: 10.1021/jm200773h  0.72
2010 Butler KV, Kalin J, Brochier C, Vistoli G, Langley B, Kozikowski AP. Rational design and simple chemistry yield a superior, neuroprotective HDAC6 inhibitor, tubastatin A Journal of the American Chemical Society. 132: 10842-10846. PMID 20614936 DOI: 10.1021/ja102758v  0.72
2009 Kalin JH, Butler KV, Kozikowski AP. Creating zinc monkey wrenches in the treatment of epigenetic disorders Current Opinion in Chemical Biology. 13: 263-271. PMID 19541531 DOI: 10.1016/j.cbpa.2009.05.007  0.72
2007 Bate AB, Kalin JH, Fooksman EM, Amorose EL, Price CM, Williams HM, Rodig MJ, Mitchell MO, Cho SH, Wang Y, Franzblau SG. Synthesis and antitubercular activity of quaternized promazine and promethazine derivatives. Bioorganic & Medicinal Chemistry Letters. 17: 1346-8. PMID 17188865 DOI: 10.1016/j.bmcl.2006.11.091  0.72
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