Jennifer L. Paulson, Ph.D. - Related publications

2007 University of California, San Francisco, San Francisco, CA 
signal transduction pathways in cells and whole organisms
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Xu W, Wang Y. Post-translational Modifications of Serine/Threonine and Histidine Kinases and Their Roles in Signal Transductions in Synechocystis Sp. PCC 6803. Applied Biochemistry and Biotechnology. PMID 33159456 DOI: 10.1007/s12010-020-03435-2   
2020 Chen CW, Huang LY, Liao CF, Chang KP, Chu YW. GasPhos: Protein Phosphorylation Site Prediction Using a New Feature Selection Approach with a GA-Aided Ant Colony System. International Journal of Molecular Sciences. 21. PMID 33114312 DOI: 10.3390/ijms21217891   
2020 Yun MW, Kim K, Park JY, Chung KY. Conformational Dynamics Analysis of MEK1 Using Hydrogen/Deuterium Exchange Mass Spectrometry. Protein and Peptide Letters. PMID 33143608 DOI: 10.2174/0929866527666201103152534   
2020 Asih PR, Prikas E, Stefanoska K, Tan ARP, Ahel HI, Ittner A. Functions of p38 MAP Kinases in the Central Nervous System. Frontiers in Molecular Neuroscience. 13: 570586. PMID 33013322 DOI: 10.3389/fnmol.2020.570586   
2020 Hu R, Xu H, Jia P, Zhao Z. KinaseMD: kinase mutations and drug response database. Nucleic Acids Research. PMID 33137204 DOI: 10.1093/nar/gkaa945   
2020 Zhang JF, Liu B, Hong I, Mo A, Roth RH, Tenner B, Lin W, Zhang JZ, Molina RS, Drobizhev M, Hughes TE, Tian L, Huganir RL, Mehta S, Zhang J. An ultrasensitive biosensor for high-resolution kinase activity imaging in awake mice. Nature Chemical Biology. PMID 32989297 DOI: 10.1038/s41589-020-00660-y   
2020 Qiao G, Bi K, Liu J, Cao S, Liu M, Pešić M, Lin X. Protein kinases as targets for developing anticancer agents from marine organisms. Biochimica Et Biophysica Acta. General Subjects. 129759. PMID 33038451 DOI: 10.1016/j.bbagen.2020.129759   
2020 Rajagopalan K, Dworkin J. Escherichia coli YegI is a novel Ser/Thr kinase lacking conserved motifs that localizes to the inner membrane. Febs Letters. PMID 32888201 DOI: 10.1002/1873-3468.13920   
2020 Ma H, Liu S, Liu Y, Zhu J, Han XX, Ozaki Y, Zhao B. In-situ fingerprinting phosphorylated proteins via surface-enhanced Raman spectroscopy: Single-site discrimination of Tau biomarkers in Alzheimer's disease. Biosensors & Bioelectronics. 171: 112748. PMID 33113381 DOI: 10.1016/j.bios.2020.112748   
2020 Tamir TY, Drewry DH, Wells C, Major MB, Axtman AD. PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor. Scientific Reports. 10: 15826. PMID 32985588 DOI: 10.1038/s41598-020-72869-9   
2020 Kim PR, Zhang S, Rahmat MB, Koh CG. Partners in crime: POPX2 phosphatase and its interacting proteins in cancer. Cell Death & Disease. 11: 840. PMID 33037179 DOI: 10.1038/s41419-020-03061-0   
2020 Benn CL, Dawson LA. Clinically Precedented Protein Kinases: Rationale for Their Use in Neurodegenerative Disease. Frontiers in Aging Neuroscience. 12: 242. PMID 33117143 DOI: 10.3389/fnagi.2020.00242   
2020 Song P, Song B, Liu J, Wang X, Nan X, Wang J. Blockage of PAK1 alleviates the proliferation and invasion of NSCLC cells via inhibiting ERK and AKT signaling activity. Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. PMID 32974862 DOI: 10.1007/s12094-020-02486-5   
2020 Tran T, Mitra J, Ha T, Kavran JM. Increasing kinase domain proximity promotes MST2 autophosphorylation during Hippo signaling. The Journal of Biological Chemistry. PMID 32994222 DOI: 10.1074/jbc.RA120.015723   
2020 Rashid MM, Shatabda S, Hasan MM, Kurata H. Recent Development of Machine Learning Methods in Microbial Phosphorylation Sites. Current Genomics. 21: 194-203. PMID 33071613 DOI: 10.2174/1389202921666200427210833   
2020 Rideout HJ, Chartier-Harlin MC, Fell MJ, Hirst WD, Huntwork-Rodriguez S, Leyns CEG, Mabrouk OS, Taymans JM. The Current State-of-the Art of LRRK2-Based Biomarker Assay Development in Parkinson's Disease. Frontiers in Neuroscience. 14: 865. PMID 33013290 DOI: 10.3389/fnins.2020.00865   
2020 Faber EB, Georg GI. DFG-1 Binding: A New Residue for Developing Selective Kinase Inhibitors. Journal of Medicinal Chemistry. 63: 10221-10223. PMID 32915573 DOI: 10.1021/acs.jmedchem.0c01501   
2020 Junaid M, Akter Y, Afrose SS, Tania M, Khan MA. Biological role of AKT, and regulation of AKT signaling pathway by thymoquinone: perspectives in cancer therapeutics. Mini Reviews in Medicinal Chemistry. PMID 33019927 DOI: 10.2174/1389557520666201005143818   
2020 Taylor SS, Kaila-Sharma P, Weng JH, Aoto P, Schmidt SH, Knapp S, Mathea S, Herberg FW. Kinase Domain Is a Dynamic Hub for Driving LRRK2 Allostery. Frontiers in Molecular Neuroscience. 13: 538219. PMID 33122997 DOI: 10.3389/fnmol.2020.538219   
2020 Zarrin AA, Bao K, Lupardus P, Vucic D. Kinase inhibition in autoimmunity and inflammation. Nature Reviews. Drug Discovery. PMID 33077936 DOI: 10.1038/s41573-020-0082-8   
2020 Bogdanow B, Schmidt M, Weisbach H, Gruska I, Vetter B, Imami K, Ostermann E, Brune W, Selbach M, Hagemeier C, Wiebusch L. Cross-regulation of viral kinases with cyclin A secures shutoff of host DNA synthesis. Nature Communications. 11: 4845. PMID 32973148 DOI: 10.1038/s41467-020-18542-1   
2020 Fang CY, Lai TC, Hsiao M, Chang YC. The Diverse Roles of TAO Kinases in Health and Diseases. International Journal of Molecular Sciences. 21. PMID 33050415 DOI: 10.3390/ijms21207463   
2020 Leeming MG, O'Callaghan S, Licata L, Iannuccelli M, Surdo PL, Micarelli E, Ang CS, Nie S, Varshney S, Ameen S, Cheng HC, Williamson NA. Phosphomatics: Interactive interrogation of substrate-kinase networks in global phosphoproteomics datasets. Bioinformatics (Oxford, England). PMID 33119075 DOI: 10.1093/bioinformatics/btaa916   
2020 Xie T, Saleh T, Rossi P, Kalodimos CG. Conformational states dynamically populated by a kinase determine its function. Science (New York, N.Y.). PMID 33004676 DOI: 10.1126/science.abc2754   
2020 Laufkötter O, Laufer S, Bajorath J. Kinase inhibitor data set for systematic analysis of representative kinases across the human kinome. Data in Brief. 32: 106189. PMID 32904416 DOI: 10.1016/j.dib.2020.106189   
2020 Berginski ME, Moret N, Liu C, Goldfarb D, Sorger PK, Gomez SM. The Dark Kinase Knowledgebase: an online compendium of knowledge and experimental results of understudied kinases. Nucleic Acids Research. PMID 33079988 DOI: 10.1093/nar/gkaa853   
2020 Sharma DK, Bihani SC, Siddiqui MQ, Misra HS, Rajpurohit YS. WD40 domain of RqkA regulates its kinase activity and role in extraordinary radioresistance of . Journal of Biomolecular Structure & Dynamics. 1-14. PMID 32990194 DOI: 10.1080/07391102.2020.1824810   
2020 Tian Y, Zhao L. Metformin induces apoptosis of melanoma B16 cells via PI3K/Akt/mTOR signaling pathways. Journal of B.U.On. : Official Journal of the Balkan Union of Oncology. 25: 2066-2070. PMID 33099954   
2020 Waschbüsch D, Khan AR. Phosphorylation of Rab GTPases in the regulation of membrane trafficking. Traffic (Copenhagen, Denmark). PMID 32969543 DOI: 10.1111/tra.12765   
2020 Jhaveri K, Chang MT, Juric D, Saura C, Gambardella V, Melnyk A, Patel MR, Ribrag V, Ma CX, Aljumaily R, Bedard PL, Sachdev JC, Dunn L, Won HH, Bond J, et al. Phase I Basket Study of Taselisib, an Isoform-Selective PI3K Inhibitor, in Patients with -Mutant Cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33148674 DOI: 10.1158/1078-0432.CCR-20-2657   
2020 Ertosun MG, DİlmaÇ S, Hapİl FZ, TanriÖver G, KÖksoy S, ÖzeŞ ON. Regulation of E2F1 activity via PKA-mediated phosphorylations. Turkish Journal of Biology = Turk Biyoloji Dergisi. 44: 215-229. PMID 33110360 DOI: 10.3906/biy-2003-9   
2020 Dai C, Shen L, Jin W, Lv B, Liu P, Wang X, Yin Y, Fu Y, Liang L, Ma Z, Zhang X, Wang Y, Xu D, Chen Z. Physapubescin B enhances the sensitivity of gastric cancer cells to trametinib by inhibiting the STAT3 signaling pathway. Toxicology and Applied Pharmacology. 115273. PMID 33035574 DOI: 10.1016/j.taap.2020.115273   
2020 Stein V, Blank-Landeshammer B, Müntjes K, Märker R, Teichert I, Feldbrügge M, Sickmann A, Kück U. The STRIPAK signaling complex regulates dephosphorylation of GUL1, an RNA-binding protein that shuttles on endosomes. Plos Genetics. 16: e1008819. PMID 32997654 DOI: 10.1371/journal.pgen.1008819   
2020 Roberto J, Sykes CE, Vacratsis PO. Characterization of Phosphopeptide Positional Isomers on the Transcriptional Co-activator TAZ. Biochemistry. PMID 33086783 DOI: 10.1021/acs.biochem.0c00521   
2020 Fienberg S, Eyermann CJ, Arendse L, Basarab GS, McPhail J, Burke JE, Chibale K. Structural Basis for Inhibitor Potency and Selectivity of Plasmodium falciparum Phosphatidylinositol 4-kinase Inhibitors. Acs Infectious Diseases. PMID 32966036 DOI: 10.1021/acsinfecdis.0c00566   
2020 Jones AC, Taylor SS, Newton AC, Kornev AP. Hypothesis: Unifying model of domain architecture for conventional and novel protein kinase C isozymes. Iubmb Life. PMID 33166426 DOI: 10.1002/iub.2401   
2020 Alme EB, Toczyski DP. Redundant targeting of Isr1 by two CDKs in mitotic cells. Current Genetics. PMID 33063175 DOI: 10.1007/s00294-020-01110-x   
2020 Elzwawi A, Grafton G, Barnes NM, Mehellou Y. SPAK and OSR1 kinases bind and phosphorylate the β-Adrenergic receptor. Biochemical and Biophysical Research Communications. 532: 88-93. PMID 32828531 DOI: 10.1016/j.bbrc.2020.07.143   
2020 Huang J, Feng W, Li S, Tang H, Qin S, Li W, Gong Y, Fang Y, Liu Y, Wang S, Guo Y, Xu Z, Shen Q. Berberine Exerts Anti-cancer Activity by Modulating Adenosine Monophosphate-Activated Protein Kinase (AMPK) and the Phosphatidylinositol 3-Kinase/Protein Kinase B (PI3K/AKT) Signaling Pathways. Current Pharmaceutical Design. PMID 32988344 DOI: 10.2174/1381612826666200928155728   
2020 Huang L, Jiang S, Shi Y. Tyrosine kinase inhibitors for solid tumors in the past 20 years (2001-2020). Journal of Hematology & Oncology. 13: 143. PMID 33109256 DOI: 10.1186/s13045-020-00977-0   
2020 Jena S, Damayanti NP, Tan J, Pratt ED, Irudayaraj JMK, Parker LL. Multiplexable fluorescence lifetime imaging (FLIM) probes for Abl and Src-family kinases. Chemical Communications (Cambridge, England). PMID 33035286 DOI: 10.1039/d0cc05030j   
2020 Soamalala J, Diot S, Pellerano M, Blanquart C, Galibert M, Jullian M, Puget K, Morris MC. Fluorescent peptide biosensor for probing CDK6 activity in lung cancer cell extracts. Chembiochem : a European Journal of Chemical Biology. PMID 33112024 DOI: 10.1002/cbic.202000677   
2020 Liu R, Chen Y, Liu G, Li C, Song Y, Cao Z, Li W, Hu J, Lu C, Liu Y. PI3K/AKT pathway as a key link modulates the multidrug resistance of cancers. Cell Death & Disease. 11: 797. PMID 32973135 DOI: 10.1038/s41419-020-02998-6   
2020 Gonzalez-Magaldi M, McCabe JM, Cartwright HN, Sun N, Leahy DJ. Conserved Roles for Receptor Tyrosine Kinase Extracellular Regions in Regulating Receptor and Pathway Activity. The Biochemical Journal. PMID 33043983 DOI: 10.1042/BCJ20200702   
2020 Jones RDO, Grondine M, Borodovsky A, San Martin M, DuPont M, D'Cruz C, Schuller A, Henry R, Barry E, Castriotta L, Anjum R, Petersson K, Sahota T, Ahmed GF. A pharmacokinetic-pharmacodynamic model for the MET-TKI, savolitinib, to explore target inhibition requirements for anti-tumour activity. British Journal of Pharmacology. PMID 33125717 DOI: 10.1111/bph.15301   
2020 Xiao Q, Hu M, Chen S, Shi Z, Hu J, Xie P, Yin D. Design and synthesis of analogues of the sphingosine-1-phosphate receptor 1 agonist IMMH001 with improved phosphorylation rate in human blood. Bioorganic & Medicinal Chemistry. 28: 115722. PMID 33065444 DOI: 10.1016/j.bmc.2020.115722   
2020 Schytte GN, Christensen B, Bregenov I, Kjøge K, Scavenius C, Petersen SV, Enghild JJ, Sørensen ES. FAM20C phosphorylation of the RGDSVVYGLR motif in osteopontin inhibits interaction with the αvβ3 integrin. Journal of Cellular Biochemistry. PMID 32115754 DOI: 10.1002/jcb.29708   
2020 Zhang X, Zhang Y, Ji Z, Wang F, Zhang L, Song M, Li H. Oxidative damage mechanism in Saccharomyces cerevisiae cells exposed to tetrachlorobisphenol A. Environmental Toxicology and Pharmacology. 103507. PMID 33007436 DOI: 10.1016/j.etap.2020.103507   
2020 Sepúlveda-Sánchez JM, Gil-Gil M, Alonso-García M, Vaz Salgado MÁ, Vicente E, Mesía Barroso C, Rodríguez Sánchez Á, Durán G, De Las Peñas R, Muñoz-Langa J, Velasco G, Hernández-Laín A, Hilario A, Navarro Martín M, Benavides M, et al. Phase II Trial of Palbociclib in Recurrent Retinoblastoma-Positive Anaplastic Oligodendroglioma: A Study from the Spanish Group for Research in Neuro-Oncology (GEINO). Targeted Oncology. 15: 613-622. PMID 33025213 DOI: 10.1007/s11523-020-00754-6   
2020 Manolache A, Selescu T, Maier GL, Mentel M, Ionescu AE, Neacsu C, Babes A, Szedlacsek SE. Regulation of TRPM8 channel activity by Src-mediated tyrosine phosphorylation. Journal of Cellular Physiology. 235: 5192-5203. PMID 31729029 DOI: 10.1002/jcp.29397