William T. Arthur, Ph.D. - Publications

Affiliations: 
2002 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Cytoskeleton, Focal Adhesions

25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Watanabe K, Biesinger J, Salmans ML, Roberts BS, Arthur WT, Cleary M, Andersen B, Xie X, Dai X. Integrative ChIP-seq/microarray analysis identifies a CTNNB1 target signature enriched in intestinal stem cells and colon cancer. Plos One. 9: e92317. PMID 24651522 DOI: 10.1371/journal.pone.0092317  1
2013 Conrad W, Major MB, Cleary MA, Ferrer M, Roberts B, Marine S, Chung N, Arthur WT, Moon RT, Berndt JD, Chien AJ. FAM129B is a novel regulator of Wnt/β-catenin signal transduction in melanoma cells. F1000research. 2: 134. PMID 24358901 DOI: 10.12688/f1000research.2-134.v2  1
2010 Andersen JN, Sathyanarayanan S, Di Bacco A, Chi A, Zhang T, Chen AH, Dolinski B, Kraus M, Roberts B, Arthur W, Klinghoffer RA, Gargano D, Li L, Feldman I, Lynch B, et al. Pathway-based identification of biomarkers for targeted therapeutics: personalized oncology with PI3K pathway inhibitors. Science Translational Medicine. 2: 43ra55. PMID 20686178 DOI: 10.1126/scitranslmed.3001065  1
2010 Loboda A, Nebozhyn M, Klinghoffer R, Frazier J, Chastain M, Arthur W, Roberts B, Zhang T, Chenard M, Haines B, Andersen J, Nagashima K, Paweletz C, Lynch B, Feldman I, et al. A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors. Bmc Medical Genomics. 3: 26. PMID 20591134 DOI: 10.1186/1755-8794-3-26  1
2010 Chung N, Marine S, Smith EA, Liehr R, Smith ST, Locco L, Hudak E, Kreamer A, Rush A, Roberts B, Major MB, Moon RT, Arthur W, Cleary M, Strulovici B, et al. A 1,536-well ultra-high-throughput siRNA screen to identify regulators of the Wnt/beta-catenin pathway. Assay and Drug Development Technologies. 8: 286-94. PMID 20578927 DOI: 10.1089/adt.2009.0262  1
2009 Klinghoffer RA, Frazier J, Annis J, Berndt JD, Roberts BS, Arthur WT, Lacson R, Zhang XD, Ferrer M, Moon RT, Cleary MA. A lentivirus-mediated genetic screen identifies dihydrofolate reductase (DHFR) as a modulator of beta-catenin/GSK3 signaling. Plos One. 4: e6892. PMID 19727391 DOI: 10.1371/journal.pone.0006892  1
2009 James RG, Biechele TL, Conrad WH, Camp ND, Fass DM, Major MB, Sommer K, Yi X, Roberts BS, Cleary MA, Arthur WT, MacCoss M, Rawlings DJ, Haggarty SJ, Moon RT. Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling. Science Signaling. 2: ra25. PMID 19471023 DOI: 10.1126/scisignal.2000230  1
2008 Major MB, Roberts BS, Berndt JD, Marine S, Anastas J, Chung N, Ferrer M, Yi X, Stoick-Cooper CL, von Haller PD, Kategaya L, Chien A, Angers S, MacCoss M, Cleary MA, ... Arthur WT, et al. New regulators of Wnt/beta-catenin signaling revealed by integrative molecular screening. Science Signaling. 1: ra12. PMID 19001663 DOI: 10.1126/scisignal.2000037  1
2007 Dubash AD, Wennerberg K, García-Mata R, Menold MM, Arthur WT, Burridge K. A novel role for Lsc/p115 RhoGEF and LARG in regulating RhoA activity downstream of adhesion to fibronectin. Journal of Cell Science. 120: 3989-98. PMID 17971419 DOI: 10.1242/jcs.003806  1
2006 García-Mata R, Wennerberg K, Arthur WT, Noren NK, Ellerbroek SM, Burridge K. Analysis of activated GAPs and GEFs in cell lysates. Methods in Enzymology. 406: 425-37. PMID 16472675 DOI: 10.1016/S0076-6879(06)06031-9  1
2004 Arthur WT, Quilliam LA, Cooper JA. Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors. The Journal of Cell Biology. 167: 111-22. PMID 15479739 DOI: 10.1083/jcb.200404068  1
2004 Avalos AM, Arthur WT, Schneider P, Quest AF, Burridge K, Leyton L. Aggregation of integrins and RhoA activation are required for Thy-1-induced morphological changes in astrocytes. The Journal of Biological Chemistry. 279: 39139-45. PMID 15220352 DOI: 10.1074/jbc.M403439200  1
2004 Ellerbroek SM, Wennerberg K, Arthur WT, Dunty JM, Bowman DR, DeMali KA, Der C, Burridge K. SGEF, a RhoG guanine nucleotide exchange factor that stimulates macropinocytosis. Molecular Biology of the Cell. 15: 3309-19. PMID 15133129 DOI: 10.1091/mbc.E04-02-0146  1
2004 Ballif BA, Arnaud L, Arthur WT, Guris D, Imamoto A, Cooper JA. Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons. Current Biology : Cb. 14: 606-10. PMID 15062102 DOI: 10.1016/j.cub.2004.03.038  1
2003 Wennerberg K, Forget MA, Ellerbroek SM, Arthur WT, Burridge K, Settleman J, Der CJ, Hansen SH. Rnd proteins function as RhoA antagonists by activating p190 RhoGAP. Current Biology : Cb. 13: 1106-15. PMID 12842009 DOI: 10.1016/S0960-9822(03)00418-4  1
2003 Di Ciano-Oliveira C, Sirokmány G, Szászi K, Arthur WT, Masszi A, Peterson M, Rotstein OD, Kapus A. Hyperosmotic stress activates Rho: differential involvement in Rho kinase-dependent MLC phosphorylation and NKCC activation. American Journal of Physiology. Cell Physiology. 285: C555-66. PMID 12748065 DOI: 10.1152/ajpcell.00086.2003  1
2003 Noren NK, Arthur WT, Burridge K. Cadherin engagement inhibits RhoA via p190RhoGAP. The Journal of Biological Chemistry. 278: 13615-8. PMID 12606561 DOI: 10.1074/jbc.C200657200  1
2003 Masszi A, Di Ciano C, Sirokmány G, Arthur WT, Rotstein OD, Wang J, McCulloch CA, Rosivall L, Mucsi I, Kapus A. Central role for Rho in TGF-beta1-induced alpha-smooth muscle actin expression during epithelial-mesenchymal transition. American Journal of Physiology. Renal Physiology. 284: F911-24. PMID 12505862 DOI: 10.1152/ajprenal.00183.2002  1
2002 Arthur WT, Noren NK, Burridge K. Regulation of Rho family GTPases by cell-cell and cell-matrix adhesion. Biological Research. 35: 239-46. PMID 12415742  1
2002 Arthur WT, Ellerbroek SM, Der CJ, Burridge K, Wennerberg K. XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC. The Journal of Biological Chemistry. 277: 42964-72. PMID 12221096 DOI: 10.1074/jbc.M207401200  1
2001 Arthur WT, Burridge K. RhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity. Molecular Biology of the Cell. 12: 2711-20. PMID 11553710  1
2000 Arthur WT, Petch LA, Burridge K. Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism. Current Biology : Cb. 10: 719-22. PMID 10873807 DOI: 10.1016/S0960-9822(00)00537-6  1
2000 Reed MJ, Corsa AC, Kudravi SA, McCormick RS, Arthur WT. A deficit in collagenase activity contributes to impaired migration of aged microvascular endothelial cells. Journal of Cellular Biochemistry. 77: 116-26. PMID 10679822 DOI: 10.1002/(SICI)1097-4644(20000401)77:1<116::AID-JCB12>3.0.CO;2-7  1
1998 Arthur WT, Vernon RB, Sage EH, Reed MJ. Growth factors reverse the impaired sprouting of microvessels from aged mice. Microvascular Research. 55: 260-70. PMID 9657926 DOI: 10.1006/mvre.1998.2078  1
1997 James R, Nguyen T, Arthur W, Levine K, Williams DC. Hydrolase (β-glucanase, α-glucanase, and protease) activity in Ariolimax columbianus (banana slug) and Arion ater (garden slug) Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology. 118: 275-283. DOI: 10.1016/S0305-0491(97)00058-8  1
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