Michael B. Brenner - Publications

2011 Harvard University, Cambridge, MA, United States 

138 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zhang F, Wei K, Slowikowski K, Fonseka CY, Rao DA, Kelly S, Goodman SM, Tabechian D, Hughes LB, Salomon-Escoto K, Watts GFM, Jonsson AH, Rangel-Moreno J, Meednu N, Rozo C, ... ... Brenner MB, et al. Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry. Nature Immunology. PMID 31061532 DOI: 10.1038/s41590-019-0378-1  0.56
2019 Madarampalli B, Watts GFM, Panipinto PM, Nguygen HN, Brenner MB, Noss EH. Interactions between cadherin-11 and platelet-derived growth factor receptor-alpha signaling link cell adhesion and proliferation. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 30876808 DOI: 10.1016/j.bbadis.2019.03.001  0.56
2019 Gutierrez-Arcelus M, Teslovich N, Mola AR, Polidoro RB, Nathan A, Kim H, Hannes S, Slowikowski K, Watts GFM, Korsunsky I, Brenner MB, Raychaudhuri S, Brennan PJ. Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions. Nature Communications. 10: 687. PMID 30737409 DOI: 10.1038/s41467-019-08604-4  0.56
2017 Brennan PJ, Cheng TY, Pellicci DG, Watts GFM, Veerapen N, Young DC, Rossjohn J, Besra GS, Godfrey DI, Brenner MB, Moody DB. Structural determination of lipid antigens captured at the CD1d-T-cell receptor interface. Proceedings of the National Academy of Sciences of the United States of America. PMID 28716901 DOI: 10.1073/pnas.1705882114  0.6
2017 Nguyen HN, Noss EH, Mizoguchi F, Huppertz C, Wei KS, Watts GF, Brenner MB. Autocrine Loop Involving IL-6 Family Member LIF, LIF Receptor, and STAT4 Drives Sustained Fibroblast Production of Inflammatory Mediators. Immunity. 46: 220-232. PMID 28228280 DOI: 10.1016/j.immuni.2017.01.004  0.52
2016 Fineran P, Lloyd-Evans E, Lack NA, Platt N, Davis LC, Morgan AJ, Höglinger D, Tatituri RV, Clark S, Williams IM, Tynan P, Al Eisa N, Nazarova E, Williams A, Galione A, ... ... Brenner MB, et al. Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway. Wellcome Open Research. 1: 18. PMID 28008422 DOI: 10.12688/wellcomeopenres.10036.1  0.6
2016 Kohlgruber AC, Donado CA, LaMarche NM, Brenner MB, Brennan PJ. Activation strategies for invariant natural killer T cells. Immunogenetics. PMID 27457886 DOI: 10.1007/s00251-016-0944-8  0.48
2016 Encarnação M, Espada L, Escrevente C, Mateus D, Ramalho J, Michelet X, Santarino I, Hsu VW, Brenner MB, Barral D, Vieira OV. A Rab3a-dependent complex essential for lysosome positioning and plasma membrane repair. The Journal of Cell Biology. 213: 631-40. PMID 27325790 DOI: 10.1083/jcb.201511093  0.88
2015 Van Rhijn I, van Berlo T, Hilmenyuk T, Cheng TY, Wolf BJ, Tatituri RV, Uldrich AP, Napolitani G, Cerundolo V, Altman JD, Willemsen P, Huang S, Rossjohn J, Besra GS, Brenner MB, et al. Human autoreactive T cells recognize CD1b and phospholipids. Proceedings of the National Academy of Sciences of the United States of America. PMID 26621732 DOI: 10.1073/pnas.1520947112  0.6
2015 Noss EH, Nguyen HN, Chang SK, Watts GF, Brenner MB. Genetic polymorphism directs IL-6 expression in fibroblasts but not selected other cell types. Proceedings of the National Academy of Sciences of the United States of America. PMID 26578807 DOI: 10.1073/pnas.1520861112  0.96
2015 Vomhof-DeKrey EE, Yates J, Hägglöf T, Lanthier P, Amiel E, Veerapen N, Besra GS, Karlsson MC, Leadbetter EA. Cognate interaction with iNKT cells expands IL-10-producing B regulatory cells. Proceedings of the National Academy of Sciences of the United States of America. 112: 12474-9. PMID 26392556 DOI: 10.1073/pnas.1504790112  0.96
2015 Wolf BJ, Tatituri RV, Almeida CF, Le Nours J, Bhowruth V, Johnson D, Uldrich AP, Hsu FF, Brigl M, Besra GS, Rossjohn J, Godfrey DI, Brenner MB. Identification of a Potent Microbial Lipid Antigen for Diverse NKT Cells. Journal of Immunology (Baltimore, Md. : 1950). 195: 2540-51. PMID 26254340 DOI: 10.4049/jimmunol.1501019  0.96
2015 Ermann J, Rao DA, Teslovich NC, Brenner MB, Raychaudhuri S. Immune cell profiling to guide therapeutic decisions in rheumatic diseases. Nature Reviews. Rheumatology. PMID 26034835 DOI: 10.1038/nrrheum.2015.71  0.96
2015 Noss EH, Watts GF, Zocco D, Keller TL, Whitman M, Blobel CP, Lee DM, Brenner MB. Evidence for cadherin-11 cleavage in the synovium and partial characterization of its mechanism. Arthritis Research & Therapy. 17: 126. PMID 25975695 DOI: 10.1186/s13075-015-0647-9  0.96
2015 Kim EY, Lynch L, Brennan PJ, Cohen NR, Brenner MB. The transcriptional programs of iNKT cells. Seminars in Immunology. 27: 26-32. PMID 25841627 DOI: 10.1016/j.smim.2015.02.005  0.96
2015 Garg S, Brenner MB. RNAi screens of lysosomal trafficking. Methods in Cell Biology. 126: 119-38. PMID 25665444 DOI: 10.1016/bs.mcb.2014.10.030  0.96
2015 Tatituri RV, Wolf BJ, Brenner MB, Turk J, Hsu FF. Characterization of polar lipids of Listeria monocytogenes by HCD and low-energy CAD linear ion-trap mass spectrometry with electrospray ionization. Analytical and Bioanalytical Chemistry. 407: 2519-28. PMID 25656850 DOI: 10.1007/s00216-015-8480-1  0.96
2015 Michelet X, Garg S, Wolf BJ, Tuli A, Ricciardi-Castagnoli P, Brenner MB. MHC class II presentation is controlled by the lysosomal small GTPase, Arl8b. Journal of Immunology (Baltimore, Md. : 1950). 194: 2079-88. PMID 25637027 DOI: 10.4049/jimmunol.1401072  0.96
2015 Lynch L, Michelet X, Zhang S, Brennan PJ, Moseman A, Lester C, Besra G, Vomhof-Dekrey EE, Tighe M, Koay HF, Godfrey DI, Leadbetter EA, Sant'Angelo DB, von Andrian U, Brenner MB. Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T(reg) cells and macrophages in adipose tissue. Nature Immunology. 16: 85-95. PMID 25436972 DOI: 10.1038/ni.3047  0.96
2014 Brennan PJ, Tatituri RV, Heiss C, Watts GF, Hsu FF, Veerapen N, Cox LR, Azadi P, Besra GS, Brenner MB. Activation of iNKT cells by a distinct constituent of the endogenous glucosylceramide fraction. Proceedings of the National Academy of Sciences of the United States of America. 111: 13433-8. PMID 25197085 DOI: 10.1073/pnas.1415357111  0.96
2014 Porcelli S, Yockey CE, Brenner MB, Balk SP. Pillars article: analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- α/β T cells demonstrates preferential use of several Vβ genes and an invariant TCR α chain. J. Exp. Med. 1993. 178: 1-16. Journal of Immunology (Baltimore, Md. : 1950). 193: 977-92. PMID 25049428  0.48
2014 Hu X, Kim H, Raj T, Brennan PJ, Trynka G, Teslovich N, Slowikowski K, Chen WM, Onengut S, Baecher-Allan C, De Jager PL, Rich SS, Stranger BE, Brenner MB, Raychaudhuri S. Regulation of gene expression in autoimmune disease loci and the genetic basis of proliferation in CD4+ effector memory T cells. Plos Genetics. 10: e1004404. PMID 24968232 DOI: 10.1371/journal.pgen.1004404  0.96
2014 Wu M, Pedroza M, Lafyatis R, George AT, Mayes MD, Assassi S, Tan FK, Brenner MB, Agarwal SK. Identification of cadherin 11 as a mediator of dermal fibrosis and possible role in systemic sclerosis. Arthritis & Rheumatology (Hoboken, N.J.). 66: 1010-21. PMID 24757152 DOI: 10.1002/art.38275  0.96
2014 Assefnia S, Dakshanamurthy S, Guidry Auvil JM, Hampel C, Anastasiadis PZ, Kallakury B, Uren A, Foley DW, Brown ML, Shapiro L, Brenner M, Haigh D, Byers SW. Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies. Oncotarget. 5: 1458-74. PMID 24681547  0.96
2014 Bassiri H, Das R, Guan P, Barrett DM, Brennan PJ, Banerjee PP, Wiener SJ, Orange JS, Brenner MB, Grupp SA, Nichols KE. iNKT cell cytotoxic responses control T-lymphoma growth in vitro and in vivo . Cancer Immunology Research. 2: 59-69. PMID 24563871 DOI: 10.1158/2326-6066.CIR-13-0104  0.96
2014 Gu Z, Liu F, Tonkova EA, Lee SY, Tschumperlin DJ, Brenner MB. Soft matrix is a natural stimulator for cellular invasiveness. Molecular Biology of the Cell. 25: 457-69. PMID 24336521 DOI: 10.1091/mbc.E13-05-0260  0.96
2013 Hu X, Kim H, Brennan PJ, Han B, Baecher-Allan CM, De Jager PL, Brenner MB, Raychaudhuri S. Application of user-guided automated cytometric data analysis to large-scale immunoprofiling of invariant natural killer T cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 19030-5. PMID 24191009 DOI: 10.1073/pnas.1318322110  0.96
2013 Tuli A, Thiery J, James AM, Michelet X, Sharma M, Garg S, Sanborn KB, Orange JS, Lieberman J, Brenner MB. Arf-like GTPase Arl8b regulates lytic granule polarization and natural killer cell-mediated cytotoxicity. Molecular Biology of the Cell. 24: 3721-35. PMID 24088571 DOI: 10.1091/mbc.E13-05-0259  0.96
2013 Brennan PJ, Brigl M, Brenner MB. Invariant natural killer T cells: an innate activation scheme linked to diverse effector functions. Nature Reviews. Immunology. 13: 101-17. PMID 23334244 DOI: 10.1038/nri3369  0.96
2013 Tatituri RV, Watts GF, Bhowruth V, Barton N, Rothchild A, Hsu FF, Almeida CF, Cox LR, Eggeling L, Cardell S, Rossjohn J, Godfrey DI, Behar SM, Besra GS, Brenner MB, et al. Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs. Proceedings of the National Academy of Sciences of the United States of America. 110: 1827-32. PMID 23307809 DOI: 10.1073/pnas.1220601110  0.96
2013 Sanderson JP, Brennan PJ, Mansour S, Matulis G, Patel O, Lissin N, Godfrey DI, Kawahara K, Zähringer U, Rossjohn J, Brenner MB, Gadola SD. CD1d protein structure determines species-selective antigenicity of isoglobotrihexosylceramide (iGb3) to invariant NKT cells. European Journal of Immunology. 43: 815-25. PMID 23280365 DOI: 10.1002/eji.201242952  0.96
2013 Cohen NR, Brennan PJ, Shay T, Watts GF, Brigl M, Kang J, Brenner MB. Shared and distinct transcriptional programs underlie the hybrid nature of iNKT cells. Nature Immunology. 14: 90-9. PMID 23202270 DOI: 10.1038/ni.2490  0.96
2012 Barral DC, Garg S, Casalou C, Watts GF, Sandoval JL, Ramalho JS, Hsu VW, Brenner MB. Arl13b regulates endocytic recycling traffic. Proceedings of the National Academy of Sciences of the United States of America. 109: 21354-9. PMID 23223633 DOI: 10.1073/pnas.1218272110  0.96
2012 Chen Y, Rice W, Gu Z, Li J, Huang J, Brenner MB, Van Hoek A, Xiong J, Gundersen GG, Norman JC, Hsu VW, Fenton RA, Brown D, Lu HA. Aquaporin 2 promotes cell migration and epithelial morphogenesis. Journal of the American Society of Nephrology : Jasn. 23: 1506-17. PMID 22859853 DOI: 10.1681/ASN.2012010079  0.96
2012 Narayan K, Sylvia KE, Malhotra N, Yin CC, Martens G, Vallerskog T, Kornfeld H, Xiong N, Cohen NR, Brenner MB, Berg LJ, Kang J. Intrathymic programming of effector fates in three molecularly distinct γδ T cell subtypes. Nature Immunology. 13: 511-8. PMID 22473038 DOI: 10.1038/ni.2247  0.48
2012 Malhotra D, Fletcher AL, Astarita J, Lukacs-Kornek V, Tayalia P, Gonzalez SF, Elpek KG, Chang SK, Knoblich K, Hemler ME, Brenner MB, Carroll MC, Mooney DJ, Turley SJ. Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks. Nature Immunology. 13: 499-510. PMID 22466668 DOI: 10.1038/ni.2262  0.96
2012 León L, Tatituri RV, Grenha R, Sun Y, Barral DC, Minnaard AJ, Bhowruth V, Veerapen N, Besra GS, Kasmar A, Peng W, Moody DB, Grabowski GA, Brenner MB. Saposins utilize two strategies for lipid transfer and CD1 antigen presentation. Proceedings of the National Academy of Sciences of the United States of America. 109: 4357-64. PMID 22331868 DOI: 10.1073/pnas.1200764109  0.96
2012 Tatituri RV, Brenner MB, Turk J, Hsu FF. Structural elucidation of diglycosyl diacylglycerol and monoglycosyl diacylglycerol from Streptococcus pneumoniae by multiple-stage linear ion-trap mass spectrometry with electrospray ionization. Journal of Mass Spectrometry : Jms. 47: 115-23. PMID 22282097 DOI: 10.1002/jms.2033  0.96
2012 King IL, Fortier A, Tighe M, Dibble J, Watts GF, Veerapen N, Haberman AM, Besra GS, Mohrs M, Brenner MB, Leadbetter EA. Invariant natural killer T cells direct B cell responses to cognate lipid antigen in an IL-21-dependent manner. Nature Immunology. 13: 44-50. PMID 22120118 DOI: 10.1038/ni.2172  0.96
2012 Schneider DJ, Wu M, Le TT, Cho SH, Brenner MB, Blackburn MR, Agarwal SK. Cadherin-11 contributes to pulmonary fibrosis: potential role in TGF-β production and epithelial to mesenchymal transition. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 503-12. PMID 21990376 DOI: 10.1096/fj.11-186098  0.96
2011 Noss EH, Chang SK, Watts GF, Brenner MB. Modulation of matrix metalloproteinase production by rheumatoid arthritis synovial fibroblasts after cadherin 11 engagement. Arthritis and Rheumatism. 63: 3768-78. PMID 22127696 DOI: 10.1002/art.30630  0.96
2011 Cohen NR, Tatituri RV, Rivera A, Watts GF, Kim EY, Chiba A, Fuchs BB, Mylonakis E, Besra GS, Levitz SM, Brigl M, Brenner MB. Innate recognition of cell wall β-glucans drives invariant natural killer T cell responses against fungi. Cell Host & Microbe. 10: 437-50. PMID 22100160 DOI: 10.1016/j.chom.2011.09.011  0.96
2011 Brennan PJ, Tatituri RV, Brigl M, Kim EY, Tuli A, Sanderson JP, Gadola SD, Hsu FF, Besra GS, Brenner MB. Invariant natural killer T cells recognize lipid self antigen induced by microbial danger signals. Nature Immunology. 12: 1202-11. PMID 22037601 DOI: 10.1038/ni.2143  0.96
2011 Garg S, Sharma M, Ung C, Tuli A, Barral DC, Hava DL, Veerapen N, Besra GS, Hacohen N, Brenner MB. Lysosomal trafficking, antigen presentation, and microbial killing are controlled by the Arf-like GTPase Arl8b. Immunity. 35: 182-93. PMID 21802320 DOI: 10.1016/j.immuni.2011.06.009  0.96
2011 Brigl M, Tatituri RV, Watts GF, Bhowruth V, Leadbetter EA, Barton N, Cohen NR, Hsu FF, Besra GS, Brenner MB. Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection. The Journal of Experimental Medicine. 208: 1163-77. PMID 21555485 DOI: 10.1084/jem.20102555  0.96
2011 Chang SK, Noss EH, Chen M, Gu Z, Townsend K, Grenha R, Leon L, Lee SY, Lee DM, Brenner MB. Cadherin-11 regulates fibroblast inflammation. Proceedings of the National Academy of Sciences of the United States of America. 108: 8402-7. PMID 21536877 DOI: 10.1073/pnas.1019437108  0.96
2011 Gu Z, Noss EH, Hsu VW, Brenner MB. Integrins traffic rapidly via circular dorsal ruffles and macropinocytosis during stimulated cell migration. The Journal of Cell Biology. 193: 61-70. PMID 21464228 DOI: 10.1083/jcb.201007003  0.96
2010 Veerapen N, Leadbetter EA, Brenner MB, Cox LR, Besra GS. Synthesis of a novel alpha-galactosyl ceramide haptenated-lipid antigen, a useful tool in demonstrating the involvement of iNKT cells in the production of antilipid antibodies. Bioconjugate Chemistry. 21: 741-7. PMID 20345125 DOI: 10.1021/bc9005255  0.96
2010 Porcelli S, Brenner MB, Greenstein JL, Terhorst C, Balk SP, Bleicher PA. Recognition of Cluster of Differentiation 1 Antigens by Human CD4-CD8- CytolyticT Lymphocyte. Nature. 1989. 341: 447-450. 1989. Journal of Immunology (Baltimore, Md. : 1950). 184: 3306-9. PMID 20304831  0.48
2010 Chang SK, Gu Z, Brenner MB. Fibroblast-like synoviocytes in inflammatory arthritis pathology: the emerging role of cadherin-11. Immunological Reviews. 233: 256-66. PMID 20193004 DOI: 10.1111/j.0105-2896.2009.00854.x  0.96
2010 Odyniec AN, Barral DC, Garg S, Tatituri RV, Besra GS, Brenner MB. Regulation of CD1 antigen-presenting complex stability. The Journal of Biological Chemistry. 285: 11937-47. PMID 20133943 DOI: 10.1074/jbc.M109.077933  0.96
2010 Muindi K, Cernadas M, Watts GF, Royle L, Neville DC, Dwek RA, Besra GS, Rudd PM, Butters TD, Brenner MB. Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphingolipids presented by CD1d [corrected]. Proceedings of the National Academy of Sciences of the United States of America. 107: 3052-7. PMID 20133624 DOI: 10.1073/pnas.0915056107  0.96
2010 Kiener HP, Watts GF, Cui Y, Wright J, Thornhill TS, Sköld M, Behar SM, Niederreiter B, Lu J, Cernadas M, Coyle AJ, Sims GP, Smolen J, Warman ML, Brenner MB, et al. Synovial fibroblasts self-direct multicellular lining architecture and synthetic function in three-dimensional organ culture. Arthritis and Rheumatism. 62: 742-52. PMID 20131230 DOI: 10.1002/art.27285  0.48
2010 Cernadas M, Cavallari M, Watts G, Mori L, De Libero G, Brenner MB. Early recycling compartment trafficking of CD1a is essential for its intersection and presentation of lipid antigens. Journal of Immunology (Baltimore, Md. : 1950). 184: 1235-41. PMID 20026739 DOI: 10.4049/jimmunol.0804140  0.96
2010 Brigl M, Brenner MB. How invariant natural killer T cells respond to infection by recognizing microbial or endogenous lipid antigens. Seminars in Immunology. 22: 79-86. PMID 19948416 DOI: 10.1016/j.smim.2009.10.006  0.96
2010 Muindi K, Cernadas M, Watts GFM, Royle L, Neville DCA, Dwek RA, Besra GS, Rudd PM, Butters TD, Brenner MB. Activation state and intracellular trafficking contribute to the repertoire of endogenous glycosphinogolipids presented by CD1d (Proceedings of the National Academy of Sciences of the United States of America (2010) 107 (3052-3057)10.1073/pnas.0915056107) Proceedings of the National Academy of Sciences of the United States of America. 107: 6118. DOI: 10.1073/pnas.1001448107  0.96
2009 Chiba A, Cohen N, Brigl M, Brennan PJ, Besra GS, Brenner MB. Rapid and reliable generation of invariant natural killer T-cell lines in vitro. Immunology. 128: 324-33. PMID 20067532 DOI: 10.1111/j.1365-2567.2009.03130.x  0.96
2009 Felio K, Nguyen H, Dascher CC, Choi HJ, Li S, Zimmer MI, Colmone A, Moody DB, Brenner MB, Wang CR. CD1-restricted adaptive immune responses to Mycobacteria in human group 1 CD1 transgenic mice. The Journal of Experimental Medicine. 206: 2497-509. PMID 19808251 DOI: 10.1084/jem.20090898  0.48
2009 Modlin RL, Brenner MB. T cell responses in microbial infection. Current Opinion in Immunology. 21: 365-6. PMID 19643590 DOI: 10.1016/j.coi.2009.07.007  0.96
2009 Veerapen N, Brigl M, Garg S, Cerundolo V, Cox LR, Brenner MB, Besra GS. Synthesis and biological activity of alpha-galactosyl ceramide KRN7000 and galactosyl (alpha1-->2) galactosyl ceramide. Bioorganic & Medicinal Chemistry Letters. 19: 4288-91. PMID 19502056 DOI: 10.1016/j.bmcl.2009.05.095  0.96
2009 Cohen NR, Garg S, Brenner MB. Antigen Presentation by CD1 Lipids, T Cells, and NKT Cells in Microbial Immunity. Advances in Immunology. 102: 1-94. PMID 19477319 DOI: 10.1016/S0065-2776(09)01201-2  0.96
2009 Van Rhijn I, Young DC, De Jong A, Vazquez J, Cheng TY, Talekar R, Barral DC, Barral D, León L, Brenner MB, Katz JT, Riese R, Ruprecht RM, O'Connor PB, Costello CE, et al. CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids. The Journal of Experimental Medicine. 206: 1409-22. PMID 19468063 DOI: 10.1084/jem.20082480  0.48
2009 Kiener HP, Niederreiter B, Lee DM, Jimenez-Boj E, Smolen JS, Brenner MB. Cadherin 11 promotes invasive behavior of fibroblast-like synoviocytes. Arthritis and Rheumatism. 60: 1305-10. PMID 19404963 DOI: 10.1002/art.24453  0.96
2009 Cernadas M, Lu J, Watts G, Brenner MB. CD1a expression defines an interleukin-12 producing population of human dendritic cells. Clinical and Experimental Immunology. 155: 523-33. PMID 19220838 DOI: 10.1111/j.1365-2249.2008.03853.x  0.96
2009 Van Rhijn I, Young DC, De Jong A, Vazquez J, Cheng TY, Talekar R, Barral DC, León L, Brenner MB, Katz JT, Riese R, Ruprecht RM, O'Connor PB, Costello CE, Porcelli SA, et al. CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids (Journal of Experimental Medicine (2009) 206, 6, (1409-1422)) Journal of Experimental Medicine. 206: 1831. DOI: 10.1084/jem.200824807172009c  0.48
2008 Sada-Ovalle I, Chiba A, Gonzales A, Brenner MB, Behar SM. Innate invariant NKT cells recognize Mycobacterium tuberculosis-infected macrophages, produce interferon-gamma, and kill intracellular bacteria. Plos Pathogens. 4: e1000239. PMID 19079582 DOI: 10.1371/journal.ppat.1000239  0.48
2008 Hava DL, van der Wel N, Cohen N, Dascher CC, Houben D, León L, Agarwal S, Sugita M, van Zon M, Kent SC, Shams H, Peters PJ, Brenner MB. Evasion of peptide, but not lipid antigen presentation, through pathogen-induced dendritic cell maturation. Proceedings of the National Academy of Sciences of the United States of America. 105: 11281-6. PMID 18685099 DOI: 10.1073/pnas.0804681105  0.96
2008 Chiba A, Dascher CC, Besra GS, Brenner MB. Rapid NKT cell responses are self-terminating during the course of microbial infection. Journal of Immunology (Baltimore, Md. : 1950). 181: 2292-302. PMID 18684918  0.96
2008 Kaser A, Hava DL, Dougan SK, Chen Z, Zeissig S, Brenner MB, Blumberg RS. Microsomal triglyceride transfer protein regulates endogenous and exogenous antigen presentation by group 1 CD1 molecules. European Journal of Immunology. 38: 2351-9. PMID 18624350 DOI: 10.1002/eji.200738102  0.96
2008 Noss EH, Brenner MB. The role and therapeutic implications of fibroblast-like synoviocytes in inflammation and cartilage erosion in rheumatoid arthritis. Immunological Reviews. 223: 252-70. PMID 18613841 DOI: 10.1111/j.1600-065X.2008.00648.x  0.96
2008 Barral DC, Cavallari M, McCormick PJ, Garg S, Magee AI, Bonifacino JS, De Libero G, Brenner MB. CD1a and MHC class I follow a similar endocytic recycling pathway. Traffic (Copenhagen, Denmark). 9: 1446-57. PMID 18564371 DOI: 10.1111/j.1600-0854.2008.00781.x  0.96
2008 Leadbetter EA, Brigl M, Illarionov P, Cohen N, Luteran MC, Pillai S, Besra GS, Brenner MB. NK T cells provide lipid antigen-specific cognate help for B cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 8339-44. PMID 18550809 DOI: 10.1073/pnas.0801375105  0.96
2008 Leslie DS, Dascher CC, Cembrola K, Townes MA, Hava DL, Hugendubler LC, Mueller E, Fox L, Roura-Mir C, Moody DB, Vincent MS, Gumperz JE, Illarionov PA, Besra GS, Reynolds CG, ... Brenner MB, et al. Serum lipids regulate dendritic cell CD1 expression and function. Immunology. 125: 289-301. PMID 18445008 DOI: 10.1111/j.1365-2567.2008.02842.x  0.96
2008 Agarwal SK, Lee DM, Kiener HP, Brenner MB. Coexpression of two mesenchymal cadherins, cadherin 11 and N-cadherin, on murine fibroblast-like synoviocytes. Arthritis and Rheumatism. 58: 1044-54. PMID 18383368 DOI: 10.1002/art.23369  0.96
2007 Barral DC, Brenner MB. CD1 antigen presentation: how it works. Nature Reviews. Immunology. 7: 929-41. PMID 18037897 DOI: 10.1038/nri2191  0.96
2007 Parisini E, Higgins JM, Liu JH, Brenner MB, Wang JH. The crystal structure of human E-cadherin domains 1 and 2, and comparison with other cadherins in the context of adhesion mechanism. Journal of Molecular Biology. 373: 401-11. PMID 17850815 DOI: 10.1016/j.jmb.2007.08.011  0.96
2007 Sugita M, Barral DC, Brenner MB. Pathways of CD1 and lipid antigen delivery, trafficking, processing, loading, and presentation. Current Topics in Microbiology and Immunology. 314: 143-64. PMID 17593660 DOI: 10.1007/978-3-540-69511-0-6  0.48
2007 Lee DM, Kiener HP, Agarwal SK, Noss EH, Watts GF, Chisaka O, Takeichi M, Brenner MB. Cadherin-11 in synovial lining formation and pathology in arthritis. Science (New York, N.Y.). 315: 1006-10. PMID 17255475 DOI: 10.1126/science.1137306  0.96
2006 Kiener HP, Lee DM, Agarwal SK, Brenner MB. Cadherin-11 induces rheumatoid arthritis fibroblast-like synoviocytes to form lining layers in vitro. The American Journal of Pathology. 168: 1486-99. PMID 16651616 DOI: 10.2353/ajpath.2006.050999  0.96
2006 Agarwal SK, Brenner MB. Role of adhesion molecules in synovial inflammation. Current Opinion in Rheumatology. 18: 268-76. PMID 16582691 DOI: 10.1097/01.bor.0000218948.42730.39  0.96
2006 Kiener HP, Stipp CS, Allen PG, Higgins JM, Brenner MB. The cadherin-11 cytoplasmic juxtamembrane domain promotes alpha-catenin turnover at adherens junctions and intercellular motility. Molecular Biology of the Cell. 17: 2366-76. PMID 16525026 DOI: 10.1091/mbc.E05-08-0745  0.96
2006 Brigl M, van den Elzen P, Chen X, Meyers JH, Wu D, Wong CH, Reddington F, Illarianov PA, Besra GS, Brenner MB, Gumperz JE. Conserved and heterogeneous lipid antigen specificities of CD1d-restricted NKT cell receptors. Journal of Immunology (Baltimore, Md. : 1950). 176: 3625-34. PMID 16517731  0.48
2006 Bry L, Brigl M, Brenner MB. CD4+-T-cell effector functions and costimulatory requirements essential for surviving mucosal infection with Citrobacter rodentium. Infection and Immunity. 74: 673-81. PMID 16369024 DOI: 10.1128/IAI.74.1.673-681.2006  0.96
2005 Vincent MS, Xiong X, Grant EP, Peng W, Brenner MB. CD1a-, b-, and c-restricted TCRs recognize both self and foreign antigens. Journal of Immunology (Baltimore, Md. : 1950). 175: 6344-51. PMID 16272286  0.96
2005 van den Elzen P, Garg S, León L, Brigl M, Leadbetter EA, Gumperz JE, Dascher CC, Cheng TY, Sacks FM, Illarionov PA, Besra GS, Kent SC, Moody DB, Brenner MB. Apolipoprotein-mediated pathways of lipid antigen presentation. Nature. 437: 906-10. PMID 16208376 DOI: 10.1038/nature04001  0.96
2005 Miller MM, Wang C, Parisini E, Coletta RD, Goto RM, Lee SY, Barral DC, Townes M, Roura-Mir C, Ford HL, Brenner MB, Dascher CC. Characterization of two avian MHC-like genes reveals an ancient origin of the CD1 family. Proceedings of the National Academy of Sciences of the United States of America. 102: 8674-9. PMID 15939884 DOI: 10.1073/pnas.0500105102  0.48
2005 van der Wel NN, Fluitsma DM, Dascher CC, Brenner MB, Peters PJ. Subcellular localization of mycobacteria in tissues and detection of lipid antigens in organelles using cryo-techniques for light and electron microscopy. Current Opinion in Microbiology. 8: 323-30. PMID 15939357 DOI: 10.1016/j.mib.2005.04.014  0.48
2005 Watts GM, Beurskens FJ, Martin-Padura I, Ballantyne CM, Klickstein LB, Brenner MB, Lee DM. Manifestations of inflammatory arthritis are critically dependent on LFA-1. Journal of Immunology (Baltimore, Md. : 1950). 174: 3668-75. PMID 15749905  0.96
2005 Kiener HP, Brenner MB. Building the synovium: cadherin-11 mediates fibroblast-like synoviocyte cell-to-cell adhesion. Arthritis Research & Therapy. 7: 49-54. PMID 15743489 DOI: 10.1186/ar1495  0.96
2005 Zajonc DM, Crispin MD, Bowden TA, Young DC, Cheng TY, Hu J, Costello CE, Rudd PM, Dwek RA, Miller MJ, Brenner MB, Moody DB, Wilson IA. Molecular mechanism of lipopeptide presentation by CD1a. Immunity. 22: 209-19. PMID 15723809 DOI: 10.1016/j.immuni.2004.12.009  0.48
2005 Hava DL, Brigl M, van den Elzen P, Zajonc DM, Wilson IA, Brenner MB. CD1 assembly and the formation of CD1-antigen complexes. Current Opinion in Immunology. 17: 88-94. PMID 15653316 DOI: 10.1016/j.coi.2004.12.003  0.96
2004 Valencia X, Higgins JM, Kiener HP, Lee DM, Podrebarac TA, Dascher CC, Watts GF, Mizoguchi E, Simmons B, Patel DD, Bhan AK, Brenner MB. Cadherin-11 provides specific cellular adhesion between fibroblast-like synoviocytes. The Journal of Experimental Medicine. 200: 1673-9. PMID 15611293 DOI: 10.1084/jem.20041545  0.96
2004 Bach JF, Bendelac A, Brenner MB, Cantor H, De Libero G, Kronenberg M, Lanier LL, Raulet DH, Shlomchik MJ, von Herrath MG. The role of innate immunity in autoimmunity. The Journal of Experimental Medicine. 200: 1527-31. PMID 15611284 DOI: 10.1084/jem.20042110  0.48
2004 Xiong X, Morita CT, Bukowski JF, Brenner MB, Dascher CC. Identification of guinea pig gammadelta T cells and characterization during pulmonary tuberculosis. Veterinary Immunology and Immunopathology. 102: 33-44. PMID 15451613 DOI: 10.1016/j.vetimm.2004.06.010  0.48
2004 Das H, Sugita M, Brenner MB. Mechanisms of Vdelta1 gammadelta T cell activation by microbial components. Journal of Immunology (Baltimore, Md. : 1950). 172: 6578-86. PMID 15153472  0.96
2004 Brigl M, Brenner MB. CD1: antigen presentation and T cell function. Annual Review of Immunology. 22: 817-90. PMID 15032598 DOI: 10.1146/annurev.immunol.22.012703.104608  0.96
2004 Moody DB, Young DC, Cheng TY, Rosat JP, Roura-Mir C, O'Connor PB, Zajonc DM, Walz A, Miller MJ, Levery SB, Wilson IA, Costello CE, Brenner MB. T cell activation by lipopeptide antigens. Science (New York, N.Y.). 303: 527-31. PMID 14739458 DOI: 10.1126/science.1089353  0.96
2004 Sugita M, Cernadas M, Brenner MB. New insights into pathways for CD1-mediated antigen presentation. Current Opinion in Immunology. 16: 90-5. PMID 14734115 DOI: 10.1016/j.coi.2003.11.014  0.96
2004 Bry L, Brenner MB. Critical role of T cell-dependent serum antibody, but not the gut-associated lymphoid tissue, for surviving acute mucosal infection with Citrobacter rodentium, an attaching and effacing pathogen. Journal of Immunology (Baltimore, Md. : 1950). 172: 433-41. PMID 14688352  0.96
2003 Brigl M, Bry L, Kent SC, Gumperz JE, Brenner MB. Mechanism of CD1d-restricted natural killer T cell activation during microbial infection. Nature Immunology. 4: 1230-7. PMID 14578883 DOI: 10.1038/ni1002  0.96
2003 Cernadas M, Sugita M, van der Wel N, Cao X, Gumperz JE, Maltsev S, Besra GS, Behar SM, Peters PJ, Brenner MB. Lysosomal localization of murine CD1d mediated by AP-3 is necessary for NK T cell development. Journal of Immunology (Baltimore, Md. : 1950). 171: 4149-55. PMID 14530337  0.96
2003 Rauch J, Gumperz J, Robinson C, Sköld M, Roy C, Young DC, Lafleur M, Moody DB, Brenner MB, Costello CE, Behar SM. Structural features of the acyl chain determine self-phospholipid antigen recognition by a CD1d-restricted invariant NKT (iNKT) cell. The Journal of Biological Chemistry. 278: 47508-15. PMID 12963715 DOI: 10.1074/jbc.M308089200  0.48
2003 Thomas SY, Hou R, Boyson JE, Means TK, Hess C, Olson DP, Strominger JL, Brenner MB, Gumperz JE, Wilson SB, Luster AD. CD1d-restricted NKT cells express a chemokine receptor profile indicative of Th1-type inflammatory homing cells. Journal of Immunology (Baltimore, Md. : 1950). 171: 2571-80. PMID 12928408  0.48
2003 van der Wel NN, Sugita M, Fluitsma DM, Cao X, Schreibelt G, Brenner MB, Peters PJ. CD1 and major histocompatibility complex II molecules follow a different course during dendritic cell maturation. Molecular Biology of the Cell. 14: 3378-88. PMID 12925770 DOI: 10.1091/mbc.E02-11-0744  0.48
2003 Peña-Cruz V, Ito S, Dascher CC, Brenner MB, Sugita M. Epidermal Langerhans cells efficiently mediate CD1a-dependent presentation of microbial lipid antigens to T cells. The Journal of Investigative Dermatology. 121: 517-21. PMID 12925210 DOI: 10.1046/j.1523-1747.2003.12429.x  0.48
2003 Dascher CC, Brenner MB. Evolutionary constraints on CD1 structure: insights from comparative genomic analysis. Trends in Immunology. 24: 412-8. PMID 12909453 DOI: 10.1016/S1471-4906(03)00179-0  0.48
2003 Dascher CC, Hiromatsu K, Xiong X, Morehouse C, Watts G, Liu G, McMurray DN, LeClair KP, Porcelli SA, Brenner MB. Immunization with a mycobacterial lipid vaccine improves pulmonary pathology in the guinea pig model of tuberculosis. International Immunology. 15: 915-25. PMID 12882829 DOI: 10.1093/intimm/dxg091  0.48
2003 Brandes M, Willimann K, Lang AB, Nam KH, Jin C, Brenner MB, Morita CT, Moser B. Flexible migration program regulates gamma delta T-cell involvement in humoral immunity. Blood. 102: 3693-701. PMID 12881309 DOI: 10.1182/blood-2003-04-1016  0.48
2003 Vincent MS, Gumperz JE, Brenner MB. Understanding the function of CD1-restricted T cells. Nature Immunology. 4: 517-23. PMID 12774075 DOI: 10.1038/ni0603-517  0.96
2003 Kawashima T, Norose Y, Watanabe Y, Enomoto Y, Narazaki H, Watari E, Tanaka S, Takahashi H, Yano I, Brenner MB, Sugita M. Cutting edge: major CD8 T cell response to live bacillus Calmette-Guérin is mediated by CD1 molecules. Journal of Immunology (Baltimore, Md. : 1950). 170: 5345-8. PMID 12759406  0.48
2003 Dodge IL, Carr MW, Cernadas M, Brenner MB. IL-6 production by pulmonary dendritic cells impedes Th1 immune responses. Journal of Immunology (Baltimore, Md. : 1950). 170: 4457-64. PMID 12707321  0.96
2003 Matsumoto I, Lee DM, Goldbach-Mansky R, Sumida T, Hitchon CA, Schur PH, Anderson RJ, Coblyn JS, Weinblatt ME, Brenner M, Duclos B, Pasquali JL, El-Gabalawy H, Mathis D, Benoist C. Low prevalence of antibodies to glucose-6-phosphate isomerase in patients with rheumatoid arthritis and a spectrum of other chronic autoimmune disorders. Arthritis and Rheumatism. 48: 944-54. PMID 12687536 DOI: 10.1002/art.10898  0.96
2003 Araki M, Kondo T, Gumperz JE, Brenner MB, Miyake S, Yamamura T. Th2 bias of CD4+ NKT cells derived from multiple sclerosis in remission. International Immunology. 15: 279-88. PMID 12578858 DOI: 10.1093/intimm/dxg029  0.96
2003 Dascher CC, Brenner MB. CD1 antigen presentation and infectious disease. Contributions to Microbiology. 10: 164-82. PMID 12530326  0.48
2003 Barthel R, Tsytsykova AV, Barczak AK, Tsai EY, Dascher CC, Brenner MB, Goldfeld AE. Regulation of tumor necrosis factor alpha gene expression by mycobacteria involves the assembly of a unique enhanceosome dependent on the coactivator proteins CBP/p300. Molecular and Cellular Biology. 23: 526-33. PMID 12509451 DOI: 10.1128/MCB.23.2.526-533.2003  0.96
2002 Leslie DS, Vincent MS, Spada FM, Das H, Sugita M, Morita CT, Brenner MB. CD1-mediated gamma/delta T cell maturation of dendritic cells. The Journal of Experimental Medicine. 196: 1575-84. PMID 12486100 DOI: 10.1084/jem.20021515  0.96
2002 Dascher CC, Hiromatsu K, Xiong X, Sugita M, Buhlmann JE, Dodge IL, Lee SY, Roura-Mir C, Watts GF, Roy CJ, Behar SM, Clemens DL, Porcelli SA, Brenner MB. Conservation of CD1 intracellular trafficking patterns between mammalian species. Journal of Immunology (Baltimore, Md. : 1950). 169: 6951-8. PMID 12471129  0.48
2002 Vincent MS, Leslie DS, Gumperz JE, Xiong X, Grant EP, Brenner MB. CD1-dependent dendritic cell instruction. Nature Immunology. 3: 1163-8. PMID 12415264 DOI: 10.1038/ni851  0.48
2002 Brennan PJ, Terwilliger T, Barry CE, Manca C, Su H, Reed M, Rutter K, Domenech P, Kaplan G, Li YJ, Wagner D, Bermudez LE, Bodnar K, Flynn J, Campos-Neto A, ... ... Brenner MB, et al. The US-Japan Cooperative Medical Science Program Tuberculosis and Leprosy Panel's 36th annual research conference, New Orleans, Louisiana, USA, 15-17 July 2001 Tuberculosis. 82: 113-135. PMID 12408170 DOI: 10.1054/tube.2002.0329  0.96
2002 Cao X, Sugita M, Van Der Wel N, Lai J, Rogers RA, Peters PJ, Brenner MB. CD1 molecules efficiently present antigen in immature dendritic cells and traffic independently of MHC class II during dendritic cell maturation. Journal of Immunology (Baltimore, Md. : 1950). 169: 4770-7. PMID 12391186  0.48
2002 Lee DM, Friend DS, Gurish MF, Benoist C, Mathis D, Brenner MB. Mast cells: a cellular link between autoantibodies and inflammatory arthritis. Science (New York, N.Y.). 297: 1689-92. PMID 12215644 DOI: 10.1126/science.1073176  0.96
2002 Hiromatsu K, Dascher CC, LeClair KP, Sugita M, Furlong ST, Brenner MB, Porcelli SA. Induction of CD1-restricted immune responses in guinea pigs by immunization with mycobacterial lipid antigens. Journal of Immunology (Baltimore, Md. : 1950). 169: 330-9. PMID 12077262  0.48
2002 Sugita M, Cao X, Watts GF, Rogers RA, Bonifacino JS, Brenner MB. Failure of trafficking and antigen presentation by CD1 in AP-3-deficient cells. Immunity. 16: 697-706. PMID 12049721 DOI: 10.1016/S1074-7613(02)00311-4  0.96
2002 Hiromatsu K, Dascher CC, Sugita M, Gingrich-Baker C, Behar SM, LeClair KP, Brenner MB, Porcelli SA. Characterization of guinea-pig group 1 CD1 proteins. Immunology. 106: 159-72. PMID 12047745  0.48
2002 Grant EP, Beckman EM, Behar SM, Degano M, Frederique D, Besra GS, Wilson IA, Porcelli SA, Furlong ST, Brenner MB. Fine specificity of TCR complementarity-determining region residues and lipid antigen hydrophilic moieties in the recognition of a CD1-lipid complex. Journal of Immunology (Baltimore, Md. : 1950). 168: 3933-40. PMID 11937549  0.6
2002 Shen Y, Zhou D, Qiu L, Lai X, Simon M, Shen L, Kou Z, Wang Q, Jiang L, Estep J, Hunt R, Clagett M, Sehgal PK, Li Y, Zeng X, ... ... Brenner MB, et al. Adaptive immune response of Vgamma2Vdelta2+ T cells during mycobacterial infections. Science (New York, N.Y.). 295: 2255-8. PMID 11910108 DOI: 10.1126/science.1068819  0.48
2002 Matsumoto I, Maccioni M, Lee DM, Maurice M, Simmons B, Brenner M, Mathis D, Benoist C. How antibodies to a ubiquitous cytoplasmic enzyme may provoke joint-specific autoimmune disease. Nature Immunology. 3: 360-5. PMID 11896391 DOI: 10.1038/ni772  0.96
2002 Gumperz JE, Miyake S, Yamamura T, Brenner MB. Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining. The Journal of Experimental Medicine. 195: 625-36. PMID 11877485 DOI: 10.1084/jem.20011786  0.96
2002 Ji H, Ohmura K, Mahmood U, Lee DM, Hofhuis FM, Boackle SA, Takahashi K, Holers VM, Walport M, Gerard C, Ezekowitz A, Carroll MC, Brenner M, Weissleder R, Verbeek JS, et al. Arthritis critically dependent on innate immune system players. Immunity. 16: 157-68. PMID 11869678 DOI: 10.1016/S1074-7613(02)00275-3  0.96
2000 Sugita M, Peters PJ, Brenner MB. Pathways for lipid antigen presentation by CD1 molecules: Nowhere for intracellular pathogens to hide Traffic. 1: 295-300. PMID 11208113  0.96
2000 Sugita M, Van Der Wel N, Rogers RA, Peters PJ, Brenner MB. CD1c molecules broadly survey the endocytic system Proceedings of the National Academy of Sciences of the United States of America. 97: 8445-8450. PMID 10890914 DOI: 10.1073/pnas.150236797  0.96
2000 Higgins JM, Cernadas M, Tan K, Irie A, Wang J, Takada Y, Brenner MB. The role of alpha and beta chains in ligand recognition by beta 7 integrins. The Journal of Biological Chemistry. 275: 25652-64. PMID 10837471 DOI: 10.1074/jbc.M001228200  0.96
2000 Taraszka KS, Higgins JM, Tan K, Mandelbrot DA, Wang JH, Brenner MB. Molecular basis for leukocyte integrin alpha(E)beta(7) adhesion to epithelial (E)-cadherin. The Journal of Experimental Medicine. 191: 1555-67. PMID 10790430 DOI: 10.1084/jem.191.9.1555  0.96
2000 Spada FM, Grant EP, Peters PJ, Sugita M, Melián A, Leslie DS, Lee HK, van Donselaar E, Hanson DA, Krensky AM, Majdic O, Porcelli SA, Morita CT, Brenner MB. Self-recognition of CD1 by gamma/delta T cells: implications for innate immunity. The Journal of Experimental Medicine. 191: 937-48. PMID 10727456 DOI: 10.1084/jem.191.6.937  0.96
1999 Sugita M, Grant EP, Van Donselaar E, Hsu VW, Rogers RA, Peters PJ, Brenner MB. Separate pathways for antigen presentation by CD1 molecules Immunity. 11: 743-752. PMID 10626896  0.96
1999 Shieh CC, Sadasivan BK, Russell GJ, Schön MP, Parker CM, Brenner MB. Lymphocyte adhesion to epithelia and endothelia mediated by the lymphocyte endothelial-epithelial cell adhesion molecule (LEEP-CAM) glycoprotein Journal of Immunology. 163: 1592-1601. PMID 10415064  0.96
1999 Ho SC, Rajagopalan S, Chaudhuri S, Shieh CC, Brenner MB, Pillai S. Membrane anchoring of calnexin facilitates its interaction with its targets Molecular Immunology. 36: 1-12. PMID 10369415 DOI: 10.1016/S0161-5890(99)00018-8  0.96
1999 Rosat JP, Grant EP, Beckman EM, Dascher CC, Sieling PA, Frederique D, Modlin RL, Porcelli SA, Furlong ST, Brenner MB. CD1-restricted microbial lipid antigen-specific recognition found in the CD8+ αβ T cell pool Journal of Immunology. 162: 366-371. PMID 9886408  0.96
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