Cynthia L. Kinsland, Ph.D. - Publications

2000 Cornell University, Ithaca, NY, United States 
Barton Professor of Chemistry

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Knaus T, Eger E, Koop J, Stipsits S, Kinsland CL, Ealick SE, Macheroux P. Reverse structural genomics: an unusual flavin-binding site in a putative protease from Bacteroides thetaiotaomicron. The Journal of Biological Chemistry. 287: 27490-8. PMID 22718753 DOI: 10.1074/jbc.M112.355388  0.96
2012 Lai RY, Huang S, Fenwick MK, Hazra A, Zhang Y, Rajashankar K, Philmus B, Kinsland C, Sanders JM, Ealick SE, Begley TP. Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate. Journal of the American Chemical Society. 134: 9157-9. PMID 22568620 DOI: 10.1021/ja302474a  0.96
2010 Kinsland C. Bacterial protein overexpression systems and strategies Comprehensive Natural Products Ii: Chemistry and Biology. 9: 695-721.  0.96
2008 Soriano EV, McCloskey DE, Kinsland C, Pegg AE, Ealick SE. Structures of the N47A and E109Q mutant proteins of pyruvoyl-dependent arginine decarboxylase from Methanococcus jannaschii. Acta Crystallographica. Section D, Biological Crystallography. 64: 377-82. PMID 18391404 DOI: 10.1107/S0907444908000474  0.96
2008 McCulloch KM, Kinsland C, Begley TP, Ealick SE. Structural studies of thiamin monophosphate kinase in complex with substrates and products. Biochemistry. 47: 3810-21. PMID 18311927 DOI: 10.1021/bi800041h  0.96
2007 Mukherjee T, Kinsland C, Begley TP. PLP catabolism: identification of the 4-pyridoxic acid dehydrogenase gene in Mesorhizobium loti MAFF303099. Bioorganic Chemistry. 35: 458-64. PMID 17868768 DOI: 10.1016/j.bioorg.2007.07.003  0.96
2005 Burns KE, Xiang Y, Kinsland CL, McLafferty FW, Begley TP. Reconstitution and biochemical characterization of a new pyridoxal-5'-phosphate biosynthetic pathway. Journal of the American Chemical Society. 127: 3682-3. PMID 15771487 DOI: 10.1021/ja042792t  0.96
2004 Toms AV, Kinsland C, McCloskey DE, Pegg AE, Ealick SE. Evolutionary links as revealed by the structure of Thermotoga maritima S-adenosylmethionine decarboxylase. The Journal of Biological Chemistry. 279: 33837-46. PMID 15150268 DOI: 10.1074/jbc.M403369200  0.96
2004 Melnick J, Lis E, Park JH, Kinsland C, Mori H, Baba T, Perkins J, Schyns G, Vassieva O, Osterman A, Begley TP. Identification of the two missing bacterial genes involved in thiamine salvage: thiamine pyrophosphokinase and thiamine kinase. Journal of Bacteriology. 186: 3660-2. PMID 15150256 DOI: 10.1128/JB.186.11.3660-3662.2004  0.96
2004 Park JH, Burns K, Kinsland C, Begley TP. Characterization of two kinases involved in thiamine pyrophosphate and pyridoxal phosphate biosynthesis in Bacillus subtilis: 4-amino-5-hydroxymethyl-2methylpyrimidine kinase and pyridoxal kinase. Journal of Bacteriology. 186: 1571-3. PMID 14973012 DOI: 10.1128/JB.186.5.1571-1573.2004  0.96
2003 Melnick JS, Sprinz KI, Reddick JJ, Kinsland C, Begley TP. An efficient enzymatic synthesis of thiamin pyrophosphate. Bioorganic & Medicinal Chemistry Letters. 13: 4139-41. PMID 14592524 DOI: 10.1016/j.bmcl.2003.07.026  0.96
2003 Park JH, Dorrestein PC, Zhai H, Kinsland C, McLafferty FW, Begley TP. Biosynthesis of the thiazole moiety of thiamin pyrophosphate (vitamin B1). Biochemistry. 42: 12430-8. PMID 14567704 DOI: 10.1021/bi034902z  0.96
2003 Choudhry AE, Mandichak TL, Broskey JP, Egolf RW, Kinsland C, Begley TP, Seefeld MA, Ku TW, Brown JR, Zalacain M, Ratnam K. Inhibitors of pantothenate kinase: novel antibiotics for staphylococcal infections. Antimicrobial Agents and Chemotherapy. 47: 2051-5. PMID 12760898 DOI: 10.1128/AAC.47.6.2051-2055.2003  0.96
2002 Anand R, Dorrestein PC, Kinsland C, Begley TP, Ealick SE. Structure of oxalate decarboxylase from Bacillus subtilis at 1.75 A resolution. Biochemistry. 41: 7659-69. PMID 12056897 DOI: 10.1021/bi0200965  0.96
2001 Xi J, Ge Y, Kinsland C, McLafferty FW, Begley TP. Biosynthesis of the thiazole moiety of thiamin in Escherichia coli: identification of an acyldisulfide-linked protein--protein conjugate that is functionally analogous to the ubiquitin/E1 complex. Proceedings of the National Academy of Sciences of the United States of America. 98: 8513-8. PMID 11438688 DOI: 10.1073/pnas.141226698  0.96
2001 Strauss E, Kinsland C, Ge Y, McLafferty FW, Begley TP. Phosphopantothenoylcysteine synthetase from Escherichia coli. Identification and characterization of the last unidentified coenzyme A biosynthetic enzyme in bacteria. The Journal of Biological Chemistry. 276: 13513-6. PMID 11278255 DOI: 10.1074/jbc.C100033200  0.96
2001 Begley TP, Kinsland C, Strauss E. The biosynthesis of coenzyme A in bacteria. Vitamins and Hormones. 61: 157-71. PMID 11153265  0.96
2001 Begley TP, Kinsland C, Mehl RA, Osterman A, Dorrestein P. The biosynthesis of nicotinamide adenine dinucleotides in bacteria. Vitamins and Hormones. 61: 103-19. PMID 11153263  0.96
2000 Mehl RA, Kinsland C, Begley TP. Identification of the Escherichia coli nicotinic acid mononucleotide adenylyltransferase gene. Journal of Bacteriology. 182: 4372-4. PMID 10894752 DOI: 10.1128/JB.182.15.4372-4374.2000  0.96
2000 Appleby TC, Kinsland C, Begley TP, Ealick SE. The crystal structure and mechanism of orotidine 5'-monophosphate decarboxylase. Proceedings of the National Academy of Sciences of the United States of America. 97: 2005-10. PMID 10681442 DOI: 10.1073/pnas.259441296  0.96
1999 Begley TP, Xi J, Kinsland C, Taylor S, McLafferty F. The enzymology of sulfur activation during thiamin and biotin biosynthesis. Current Opinion in Chemical Biology. 3: 623-9. PMID 10508664 DOI: 10.1016/S1367-5931(99)00018-6  0.96
1999 Begley TP, Downs DM, Ealick SE, McLafferty FW, Van Loon AP, Taylor S, Campobasso N, Chiu HJ, Kinsland C, Reddick JJ, Xi J. Thiamin biosynthesis in prokaryotes. Archives of Microbiology. 171: 293-300. PMID 10382260 DOI: 10.1007/s002030050713  0.96
1998 Kinsland C, Taylor SV, Kelleher NL, McLafferty FW, Begley TP. Overexpression of recombinant proteins with a C-terminal thiocarboxylate: implications for protein semisynthesis and thiamin biosynthesis. Protein Science : a Publication of the Protein Society. 7: 1839-42. PMID 10082383 DOI: 10.1002/pro.5560070821  0.96
1998 Kelleher NL, Taylor SV, Grannis D, Kinsland C, Chiu HJ, Begley TP, McLafferty FW. Efficient sequence analysis of the six gene products (7-74 kDa) from the Escherichia coli thiamin biosynthetic operon by tandem high-resolution mass spectrometry. Protein Science : a Publication of the Protein Society. 7: 1796-801. PMID 10082377 DOI: 10.1002/pro.5560070815  0.96
1998 Campobasso N, Costello CA, Kinsland C, Begley TP, Ealick SE. Crystal structure of thiaminase-I from Bacillus thiaminolyticus at 2.0 A resolution. Biochemistry. 37: 15981-9. PMID 9843405 DOI: 10.1021/bi981673l  0.96
1998 Rebeil R, Sun Y, Chooback L, Pedraza-Reyes M, Kinsland C, Begley TP, Nicholson WL. Spore photoproduct lyase from Bacillus subtilis spores is a novel iron-sulfur DNA repair enzyme which shares features with proteins such as class III anaerobic ribonucleotide reductases and pyruvate-formate lyases. Journal of Bacteriology. 180: 4879-85. PMID 9733691  0.96
1998 Taylor SV, Kelleher NL, Kinsland C, Chiu HJ, Costello CA, Backstrom AD, McLafferty FW, Begley TP. Thiamin biosynthesis in Escherichia coli. Identification of ThiS thiocarboxylate as the immediate sulfur donor in the thiazole formation. The Journal of Biological Chemistry. 273: 16555-60. PMID 9632726 DOI: 10.1074/jbc.273.26.16555  0.96
1998 Reddick JJ, Kinsland C, Nicewonger R, Christian T, Downs DM, Winkler ME, Begley TP. Overexpression, purification and characterization of two pyrimidine kinases involved in the biosynthesis of thiamin: 4-amino-5-hydroxymethyl-2- methylpyrimidine kinase and 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase Tetrahedron. 54: 15983-15991.  0.96
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