Erick Strauss, Ph.D. - Publications

2003 Cornell University, Ithaca, NY, United States 
Barton Professor of Chemistry

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Abrie JA, Molero C, Ariño J, Strauss E. Complex stability and dynamic subunit interchange modulates the disparate activities of the yeast moonlighting proteins Hal3 and Vhs3. Scientific Reports. 5: 15774. PMID 26514574 DOI: 10.1038/srep15774  1
2015 de Villiers M, Strauss E. Metabolism: Jump-starting CoA biosynthesis. Nature Chemical Biology. 11: 757-8. PMID 26379022 DOI: 10.1038/nchembio.1912  1
2015 Macuamule CJ, Tjhin ET, Jana CE, Barnard L, Koekemoer L, de Villiers M, Saliba KJ, Strauss E. A pantetheinase-resistant pantothenamide with potent, on-target, and selective antiplasmodial activity. Antimicrobial Agents and Chemotherapy. 59: 3666-8. PMID 25845876 DOI: 10.1128/AAC.04970-14  1
2014 de Villiers M, Barnard L, Koekemoer L, Snoep JL, Strauss E. Variation in pantothenate kinase type determines the pantothenamide mode of action and impacts on coenzyme A salvage biosynthesis. The Febs Journal. 281: 4731-53. PMID 25156889 DOI: 10.1111/febs.13013  1
2014 Moolman WJ, de Villiers M, Strauss E. Recent advances in targeting coenzyme A biosynthesis and utilization for antimicrobial drug development. Biochemical Society Transactions. 42: 1080-6. PMID 25110006 DOI: 10.1042/BST20140131  1
2014 Spry C, Saliba KJ, Strauss E. A miniaturized assay for measuring small molecule phosphorylation in the presence of complex matrices. Analytical Biochemistry. 451: 76-8. PMID 24333332 DOI: 10.1016/j.ab.2013.12.010  1
2013 de Villiers M, Macuamule C, Spry C, Hyun YM, Strauss E, Saliba KJ. Structural modification of pantothenamides counteracts degradation by pantetheinase and improves antiplasmodial activity. Acs Medicinal Chemistry Letters. 4: 784-9. PMID 24900746 DOI: 10.1021/ml400180d  1
2013 Molero C, Petrényi K, González A, Carmona M, Gelis S, Abrie JA, Strauss E, Ramos J, Dombradi V, Hidalgo E, Ariño J. The Schizosaccharomyces pombe fusion gene hal3 encodes three distinct activities. Molecular Microbiology. 90: 367-82. PMID 23962284 DOI: 10.1111/mmi.12370  1
2013 Spry C, Macuamule C, Lin Z, Virga KG, Lee RE, Strauss E, Saliba KJ. Pantothenamides are potent, on-target inhibitors of Plasmodium falciparum growth when serum pantetheinase is inactivated. Plos One. 8: e54974. PMID 23405100 DOI: 10.1371/journal.pone.0054974  1
2012 Wallace BD, Edwards JS, Wallen JR, Moolman WJ, van der Westhuyzen R, Strauss E, Redinbo MR, Claiborne A. Turnover-dependent covalent inactivation of Staphylococcus aureus coenzyme A-disulfide reductase by coenzyme A-mimetics: mechanistic and structural insights. Biochemistry. 51: 7699-711. PMID 22954034 DOI: 10.1021/bi301026c  1
2012 Lamprecht DA, Muneri NO, Eastwood H, Naidoo KJ, Strauss E, Jardine A. An enzyme-initiated Smiles rearrangement enables the development of an assay of MshB, the GlcNAc-Ins deacetylase of mycothiol biosynthesis. Organic & Biomolecular Chemistry. 10: 5278-88. PMID 22678300 DOI: 10.1039/c2ob25429h  1
2012 van der Westhuyzen R, Hammons JC, Meier JL, Dahesh S, Moolman WJ, Pelly SC, Nizet V, Burkart MD, Strauss E. The antibiotic CJ-15,801 is an antimetabolite that hijacks and then inhibits CoA biosynthesis. Chemistry & Biology. 19: 559-71. PMID 22633408 DOI: 10.1016/j.chembiol.2012.03.013  1
2012 Abrie JA, González A, Strauss E, Ariño J. Functional mapping of the disparate activities of the yeast moonlighting protein Hal3. The Biochemical Journal. 442: 357-68. PMID 22124281 DOI: 10.1042/BJ20111466  1
2010 Strauss E. Grand challenge commentary: Exploiting single-cell variation for new antibiotics. Nature Chemical Biology. 6: 873-5. PMID 21079594 DOI: 10.1038/nchembio.483  1
2010 van der Westhuyzen R, Strauss E. Michael acceptor-containing coenzyme A analogues as inhibitors of the atypical coenzyme A disulfide reductase from Staphylococcus aureus. Journal of the American Chemical Society. 132: 12853-5. PMID 20738089 DOI: 10.1021/ja106204m  1
2010 de Villiers J, Koekemoer L, Strauss E. 3-Fluoroaspartate and pyruvoyl-dependant aspartate decarboxylase: exploiting the unique characteristics of fluorine to probe reactivity and binding. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 10030-41. PMID 20645337 DOI: 10.1002/chem.201000622  1
2010 Spry C, van Schalkwyk DA, Strauss E, Saliba KJ. Pantothenate utilization by plasmodium as a target for antimalarial chemotherapy Infectious Disorders - Drug Targets. 10: 200-216. PMID 20334619  1
2010 Rootman I, de Villiers M, Brand LA, Strauss E. Creating cellulose-binding domain fusions of the coenzymea biosynthetic enzymes to enable reactor-based biotransformations Chemcatchem. 2: 1239-1251. DOI: 10.1002/cctc.201000197  1
2010 Strauss E, de Villiers M, Rootman I. Biocatalytic Production of Coenzyme A Analogues Chemcatchem. 2: 929-937. DOI: 10.1002/cctc.201000139  1
2010 Strauss E. Coenzyme A biosynthesis and enzymology Comprehensive Natural Products Ii: Chemistry and Biology. 7: 351-410.  1
2009 Ruiz A, González A, Muñoz I, Serrano R, Abrie JA, Strauss E, Ariño J. Moonlighting proteins Hal3 and Vhs3 form a heteromeric PPCDC with Ykl088w in yeast CoA biosynthesis. Nature Chemical Biology. 5: 920-8. PMID 19915539 DOI: 10.1038/nchembio.243  1
2008 van Wyk M, Strauss E. Development of a method for the parallel synthesis and purification of N-substituted pantothenamides, known inhibitors of coenzyme A biosynthesis and utilization. Organic & Biomolecular Chemistry. 6: 4348-55. PMID 19005594 DOI: 10.1039/b811086g  1
2008 Yang K, Strauss E, Huerta C, Zhang H. Structural basis for substrate binding and the catalytic mechanism of type III pantothenate kinase. Biochemistry. 47: 1369-80. PMID 18186650 DOI: 10.1021/bi7018578  1
2007 van Wyk M, Strauss E. One-pot preparation of coenzyme A analogues via an improved chemo-enzymatic synthesis of pre-CoA thioester synthons. Chemical Communications (Cambridge, England). 398-400. PMID 17220983 DOI: 10.1039/b613527g  1
2006 Yang K, Eyobo Y, Brand LA, Martynowski D, Tomchick D, Strauss E, Zhang H. Crystal structure of a type III pantothenate kinase: insight into the mechanism of an essential coenzyme A biosynthetic enzyme universally distributed in bacteria. Journal of Bacteriology. 188: 5532-40. PMID 16855243 DOI: 10.1128/JB.00469-06  1
2005 Brand LA, Strauss E. Characterization of a new pantothenate kinase isoform from Helicobacter pylori. The Journal of Biological Chemistry. 280: 20185-8. PMID 15795230 DOI: 10.1074/jbc.C500044200  1
2005 Strauss E, Begley TP. The selectivity for cysteine over serine in coenzyme A biosynthesis. Chembiochem : a European Journal of Chemical Biology. 6: 284-6. PMID 15593134 DOI: 10.1002/cbic.200400340  1
2004 Strauss E, Zhai H, Brand LA, McLafferty FW, Begley TP. Mechanistic studies on phosphopantothenoylcysteine decarboxylase: trapping of an enethiolate intermediate with a mechanism-based inactivating agent. Biochemistry. 43: 15520-33. PMID 15581364 DOI: 10.1021/bi048340a  1
2003 Manoj N, Strauss E, Begley TP, Ealick SE. Structure of human phosphopantothenoylcysteine synthetase at 2.3 A resolution. Structure (London, England : 1993). 11: 927-36. PMID 12906824 DOI: 10.1016/S0969-2126(03)00146-1  1
2003 Seravalli J, Gu W, Tam A, Strauss E, Begley TP, Cramer SP, Ragsdale SW. Functional copper at the acetyl-CoA synthase active site. Proceedings of the National Academy of Sciences of the United States of America. 100: 3689-94. PMID 12589021 DOI: 10.1073/pnas.0436720100  1
2003 Strauss E, Begley TP. Stereochemical studies on phosphopantothenoylcysteine decarboxylase from Escherichia coli. Bioorganic & Medicinal Chemistry Letters. 13: 339-42. PMID 12565925 DOI: 10.1016/S0960-894X(02)01018-1  1
2002 Strauss E, Begley TP. The antibiotic activity of N-pentylpantothenamide results from its conversion to ethyldethia-coenzyme a, a coenzyme a antimetabolite. The Journal of Biological Chemistry. 277: 48205-9. PMID 12372838 DOI: 10.1074/jbc.M204560200  1
2002 Ge Y, Lawhorn BG, ElNaggar M, Strauss E, Park JH, Begley TP, McLafferty FW. Top down characterization of larger proteins (45 kDa) by electron capture dissociation mass spectrometry. Journal of the American Chemical Society. 124: 672-8. PMID 11804498 DOI: 10.1021/ja011335z  1
2001 Strauss E, Begley TP. Mechanistic studies on phosphopantothenoylcysteine decarboxylase. Journal of the American Chemical Society. 123: 6449-50. PMID 11427085 DOI: 10.1021/ja016020y  1
2001 Strauss E, Kinsland C, Ge Y, McLafferty FW, Begley TP. Phosphopantothenoylcysteine synthetase from Escherichia coli. Identification and characterization of the last unidentified coenzyme A biosynthetic enzyme in bacteria. The Journal of Biological Chemistry. 276: 13513-6. PMID 11278255 DOI: 10.1074/jbc.C100033200  1
2001 Begley TP, Kinsland C, Strauss E. The biosynthesis of coenzyme A in bacteria. Vitamins and Hormones. 61: 157-71. PMID 11153265  1
1997 Mafunda BG, Modro AM, Modro TA, Strauss E, Strydom CA. Thermal fragmentation of 2-chloropentylphosphonic salts in the solid state. Counter-ion effects on reactivity and selectivity Heteroatom Chemistry. 8: 421-428.  1
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