Eugen F. Mesaros, Ph.D. - Publications

Affiliations: 
2003 Case Western Reserve University, Cleveland Heights, OH, United States 
Area:
organoiron chemistry, organocatalysts

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Ott GR, Cheng M, Learn KS, Wagner J, Gingrich DE, Lisko JG, Curry M, Mesaros EF, Ghose AK, Quail MR, Wan W, Lu L, Dobrzanski P, Albom MS, Angeles TS, et al. Discovery of Clinical Candidate CEP-37440, a Selective Inhibitor of Focal Adhesion Kinase (FAK) and Anaplastic Lymphoma Kinase (ALK). Journal of Medicinal Chemistry. PMID 27527804 DOI: 10.1021/acs.jmedchem.6b00487  1
2015 Mesaros EF, Angeles TS, Albom MS, Wagner JC, Aimone LD, Wan W, Lu L, Huang Z, Olsen M, Kordwitz E, Haltiwanger RC, Landis AJ, Cheng M, Ruggeri BA, Ator MA, et al. Piperidine-3,4-diol and piperidine-3-ol derivatives of pyrrolo[2,1-f][1,2,4]triazine as inhibitors of anaplastic lymphoma kinase. Bioorganic & Medicinal Chemistry Letters. 25: 1047-52. PMID 25655723 DOI: 10.1016/j.bmcl.2015.01.019  1
2014 Mesaros EF, Ott GR, Dorsey BD. Anaplastic lymphoma kinase inhibitors as anticancer therapeutics: a patent review. Expert Opinion On Therapeutic Patents. 24: 417-42. PMID 24476492 DOI: 10.1517/13543776.2014.877890  1
2012 Dugan BJ, Gingrich DE, Mesaros EF, Milkiewicz KL, Curry MA, Zulli AL, Dobrzanski P, Serdikoff C, Jan M, Angeles TS, Albom MS, Mason JL, Aimone LD, Meyer SL, Huang Z, et al. A selective, orally bioavailable 1,2,4-triazolo[1,5-a]pyridine-based inhibitor of Janus kinase 2 for use in anticancer therapy: discovery of CEP-33779. Journal of Medicinal Chemistry. 55: 5243-54. PMID 22594690 DOI: 10.1021/jm300248q  1
2012 Mesaros EF, Thieu TV, Wells GJ, Zificsak CA, Wagner JC, Breslin HJ, Tripathy R, Diebold JL, McHugh RJ, Wohler AT, Quail MR, Wan W, Lu L, Huang Z, Albom MS, et al. Strategies to mitigate the bioactivation of 2-anilino-7-aryl-pyrrolo[2,1-f][1,2,4]triazines: identification of orally bioavailable, efficacious ALK inhibitors. Journal of Medicinal Chemistry. 55: 115-25. PMID 22141319 DOI: 10.1021/jm2010767  1
2011 Wells-Knecht KJ, Ott GR, Cheng M, Wells GJ, Breslin HJ, Gingrich DE, Weinberg L, Mesaros EF, Huang Z, Yazdanian M, Ator MA, Aimone LD, Zeigler K, Dorsey BD. 2,7-Disubstituted-pyrrolotriazine kinase inhibitors with an unusually high degree of reactive metabolite formation. Chemical Research in Toxicology. 24: 1994-2003. PMID 22023349 DOI: 10.1021/tx200304r  1
2011 Ott GR, Wells GJ, Thieu TV, Quail MR, Lisko JG, Mesaros EF, Gingrich DE, Ghose AK, Wan W, Lu L, Cheng M, Albom MS, Angeles TS, Huang Z, Aimone LD, et al. 2,7-disubstituted-pyrrolo[2,1-f][1,2,4]triazines: new variant of an old template and application to the discovery of anaplastic lymphoma kinase (ALK) inhibitors with in vivo antitumor activity. Journal of Medicinal Chemistry. 54: 6328-41. PMID 21859094 DOI: 10.1021/jm200758k  1
2011 Zificsak CA, Theroff JP, Aimone LD, Angeles TS, Albom MS, Cheng M, Mesaros EF, Ott GR, Quail MR, Underiner TL, Wan W, Dorsey BD. Methanesulfonamido-cyclohexylamine derivatives of 2,4-diaminopyrimidine as potent ALK inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 3877-80. PMID 21632243 DOI: 10.1016/j.bmcl.2011.05.040  1
2011 Mesaros EF, Burke JP, Parrish JD, Dugan BJ, Anzalone AV, Angeles TS, Albom MS, Aimone LD, Quail MR, Wan W, Lu L, Huang Z, Ator MA, Ruggeri BA, Cheng M, et al. Novel 2,3,4,5-tetrahydro-benzo[d]azepine derivatives of 2,4-diaminopyrimidine, selective and orally bioavailable ALK inhibitors with antitumor efficacy in ALCL mouse models. Bioorganic & Medicinal Chemistry Letters. 21: 463-6. PMID 21074994 DOI: 10.1016/j.bmcl.2010.10.115  1
2010 Smith AB, Xiong H, Charnley AK, Brenner M, Mesaros EF, Kenesky CS, Di Costanzo L, Christianson DW, Hirschmann R. Design, synthesis, and structural analysis of D,L-mixed polypyrrolinones. 2. Macrocyclic hexapyrrolinones. Organic Letters. 12: 2994-7. PMID 20518572 DOI: 10.1021/Ol101008Y  1
2006 Smith AB, Mesaros EF, Meyer EA. Evolution of a total synthesis of (-)-kendomycin exploiting a Petasis-Ferrier rearrangement/ring-closing olefin metathesis strategy. Journal of the American Chemical Society. 128: 5292-9. PMID 16608366 DOI: 10.1021/ja060369+  1
2005 Smith AB, Mesaros EF, Meyer EA. Total synthesis of (-)-kendomycin exploiting a Petasis-Ferrier rearrangement/ring-closing olefin metathesis synthetic strategy. Journal of the American Chemical Society. 127: 6948-9. PMID 15884927 DOI: 10.1021/ja051420x  1
2005 Smith AB, Charnley AK, Mesaros EF, Kikuchi O, Wang W, Benowitz A, Chu CL, Feng JJ, Chen KH, Lin A, Cheng FC, Taylor L, Hirschmann R. Design, synthesis, and binding affinities of pyrrolinone-based somatostatin mimetics. Organic Letters. 7: 399-402. PMID 15673249 DOI: 10.1021/Ol0476974  1
2004 Mesaros EF, Pearson AJ, Schoffers E. Tricarbonyltris(pyridine)molybdenum(0) and its use as a Mo(0) source for allylmolybdenum(II) complexes Inorganic Syntheses. 34: 104-107.  1
2002 Pearson AJ, Mesaros EF. Diastereoselective conjugate additions to pi-allylmolybdenum complexes: a stereocontrolled route to 3,4,5-trisubstituted gamma-butyrolactones. Organic Letters. 4: 2001-4. PMID 12049502 DOI: 10.1021/Ol020043F  1
2002 Pearson AJ, Mesaros EF. Diastereoselective Conjugate Additions to π-Allylmolybdenum Complexes: A Stereocontrolled Route to 3,4,5-Trisubstituted γ-Butyrolactones Organic Letters. 4: 2001-2004. DOI: 10.1021/ol020043f  1
2001 Pearson AJ, Mesaros EF. Stereocontrolled construction of tetrahydrofurans and gamma-butyrolactones using organomolybdenum chemistry. Organic Letters. 3: 2665-8. PMID 11506604 DOI: 10.1021/Ol010121J  1
2001 Pearson AJ, Mesaros EF. Stereocontrolled construction of tetrahydrofurans and γ-butyrolactones using organomolybdenum chemistry Organic Letters. 3: 2665-2668. DOI: 10.1021/ol010121j  1
2000 Bogdan E, Grosu I, Mesaros E, Toupet L, Plé G, Mager S, Muntean L. Considerations on the stereoselective synthesis of dibrominated spiro-1,3-dioxanes. Synthesis and stereochemistry of monobrominated precursors Journal of the Chemical Society, Perkin Transactions 1. 3635-3639. DOI: 10.1039/B004282J  1
2000 Grosu I, Toupet L, Plé G, Mager S, Mesaros E, Varga A, Bogdan E. Synthesis and stereochemistry of novel dibrominated 1,5-dioxaspiro[5.5]undecane derivatives Monatshefte Fur Chemie. 131: 277-286.  1
2000 Socaci C, Grosu I, Plé G, Zwanziger HW, Mesaros E, Marginean D, Mager S. Synthesis and stereochemistry of some new chiral brominated 1,3-Dioxane derivatives Heterocyclic Communications. 6: 219-224.  1
1998 Grosu I, Plé G, Mager S, Mesaros E, Dulau A, Gego C. Study on the atropisomerism of some new 2-aryl-1,3-dioxanes Tetrahedron. 54: 2905-2916. DOI: 10.1016/S0040-4020(98)83026-3  1
1998 Grosu I, Mager S, Mesaros E, Plé G. Synthesis and stereochemistry of some new 1,3-dioxane derivatives of o-phthaldialdehyde Heterocyclic Communications. 4: 53-58.  1
1998 Mesaros E, Grosu I, Mager S, Plé G, Farcas SI. The stereochemistry of some new flexible 2,2,5,5-tetrasubstituted 1,3-dioxanes Monatshefte Fur Chemie. 129: 723-733.  1
1998 Grosu I, Mager S, Plé G, Turos I, Mesaros E, Schirger I. Synthesis and stereochemistry of some new trispiro-1,3-dioxanes with axial and helical chirality Monatshefte Fur Chemie. 129: 59-68.  1
1998 Grosu I, Mager S, Toupet L, Plé G, Mesaros E, Mihis A. Synthesis and stereochemistry of some new 1,3-dioxane derivatives of 1,4-benzenedicarbaldehyde Acta Chemica Scandinavica. 52: 366-371.  1
1997 Grosu I, Mager S, Plé G, Plé N, Toscano A, Mesaros E, Martinez R. Synthesis and stereochemistry of some 1,3-dioxane diacetals of o-phthaldialdehyde Liebigs Annales. 2371-2377.  1
1996 Grosu I, Mager S, Plé G, Mesaros E. Synthesis and stereochemistry of some dispiro-1,3-dioxanes with axial and helical chirality Tetrahedron. 52: 12783-12798. DOI: 10.1016/0040-4020(96)00760-0  1
1995 Grosu I, Mager S, Plé G, Martinez R, Muntean L, Mesaros E. Synthesis and stereochemistry of chiral 1,3-dioxanic compounds obtained from α-alkylated β-ketoesters Heterocycles. 41: 2233-2244. DOI: 10.3987/Com-95-7146  1
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