David J. Pagliarini, Ph.D. - Publications

Affiliations: 
2005 University of California, San Diego, La Jolla, CA 
Area:
Protein Tyrosine Phosphatase, Dual=specific Phosphatase, PTEN

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Gregg T, Sdao SM, Dhillon RS, Rensvold JW, Lewandowski SL, Pagliarini DJ, Denu JM, Merrins MJ. Obesity-dependent CDK1 signaling stimulates mitochondrial respiration at complex I in pancreatic β-cells. The Journal of Biological Chemistry. PMID 30700550 DOI: 10.1074/jbc.RA118.006085  0.4
2019 Subramanian K, Jochem A, Le Vasseur M, Lewis S, Paulson BR, Reddy TR, Russell JD, Coon JJ, Pagliarini DJ, Nunnari J. Coenzyme Q biosynthetic proteins assemble in a substrate-dependent manner into domains at ER-mitochondria contacts. The Journal of Cell Biology. PMID 30674579 DOI: 10.1083/jcb.201808044  0.44
2019 Lohman DC, Aydin D, Von Bank HC, Smith RW, Linke V, Weisenhorn E, McDevitt MT, Hutchins P, Wilkerson EM, Wancewicz B, Russell J, Stefely MS, Beebe ET, Jochem A, Coon JJ, ... ... Pagliarini DJ, et al. An Isoprene Lipid-Binding Protein Promotes Eukaryotic Coenzyme Q Biosynthesis. Molecular Cell. PMID 30661980 DOI: 10.1016/j.molcel.2018.11.033  0.44
2018 Schaffer LV, Rensvold JW, Shortreed MR, Cesnik AJ, Jochem A, Scalf M, Frey BL, Pagliarini DJ, Smith LM. Identification and Quantification of Murine Mitochondrial Proteoforms Using an Integrated Top-Down and Intact-Mass Strategy. Journal of Proteome Research. PMID 30180576 DOI: 10.1021/acs.jproteome.8b00469  0.4
2018 Jha P, McDevitt MT, Gupta R, Quiros PM, Williams EG, Gariani K, Sleiman MB, Diserens L, Jochem A, Ulbrich A, Coon JJ, Auwerx J, Pagliarini DJ. Systems Analyses Reveal Physiological Roles and Genetic Regulators of Liver Lipid Species. Cell Systems. PMID 29909277 DOI: 10.1016/j.cels.2018.05.016  0.44
2018 Jha P, McDevitt MT, Halilbasic E, Williams EG, Quiros PM, Gariani K, Sleiman MB, Gupta R, Ulbrich A, Jochem A, Coon JJ, Trauner M, Pagliarini DJ, Auwerx J. Genetic Regulation of Plasma Lipid Species and Their Association with Metabolic Phenotypes. Cell Systems. PMID 29909275 DOI: 10.1016/j.cels.2018.05.009  0.44
2017 Lapointe CP, Stefely JA, Jochem A, Hutchins PD, Wilson GM, Kwiecien NW, Coon JJ, Wickens M, Pagliarini DJ. Multi-omics Reveal Specific Targets of the RNA-Binding Protein Puf3p and Its Orchestration of Mitochondrial Biogenesis. Cell Systems. PMID 29248374 DOI: 10.1016/j.cels.2017.11.012  0.44
2017 Veling MT, Reidenbach AG, Freiberger EC, Kwiecien NW, Hutchins PD, Drahnak MJ, Jochem A, Ulbrich A, Rush MJP, Russell JD, Coon JJ, Pagliarini DJ. Multi-omic Mitoprotease Profiling Defines a Role for Oct1p in Coenzyme Q Production. Molecular Cell. 68: 970-977.e11. PMID 29220658 DOI: 10.1016/j.molcel.2017.11.023  0.44
2017 Reidenbach AG, Kemmerer ZA, Aydin D, Jochem A, McDevitt MT, Hutchins PD, Stark JL, Stefely JA, Reddy T, Hebert AS, Wilkerson EM, Johnson IE, Bingman CA, Markley JL, Coon JJ, ... ... Pagliarini DJ, et al. Conserved Lipid and Small-Molecule Modulation of COQ8 Reveals Regulation of the Ancient Kinase-like UbiB Family. Cell Chemical Biology. PMID 29198567 DOI: 10.1016/j.chembiol.2017.11.001  0.44
2017 Chung J, Wittig JG, Ghamari A, Maeda M, Dailey TA, Bergonia H, Kafina MD, Coughlin EE, Minogue CE, Hebert AS, Li L, Kaplan J, Lodish HF, Bauer DE, Orkin SH, ... ... Pagliarini DJ, et al. Erythropoietin signaling regulates heme biosynthesis. Elife. 6. PMID 28553927 DOI: 10.7554/eLife.24767  0.44
2017 Guo X, Niemi NM, Coon JJ, Pagliarini DJ. Integrative proteomics and biochemical analyses define Ptc6p as the Saccharomyces cerevisiae pyruvate dehydrogenase phosphatase. The Journal of Biological Chemistry. PMID 28539364 DOI: 10.1074/jbc.M117.787341  0.44
2017 Guo X, Niemi NM, Hutchins PD, Condon SG, Jochem A, Ulbrich A, Higbee AJ, Russell JD, Senes A, Coon JJ, Pagliarini DJ. Ptc7p Dephosphorylates Select Mitochondrial Proteins to Enhance Metabolic Function. Cell Reports. 18: 307-313. PMID 28076776 DOI: 10.1016/j.celrep.2016.12.049  0.44
2016 Stefely JA, Kwiecien NW, Freiberger EC, Richards AL, Jochem A, Rush MJ, Ulbrich A, Robinson KP, Hutchins PD, Veling MT, Guo X, Kemmerer ZA, Connors KJ, Trujillo EA, Sokol J, ... ... Pagliarini DJ, et al. Mitochondrial protein functions elucidated by multi-omic mass spectrometry profiling. Nature Biotechnology. PMID 27669165 DOI: 10.1038/nbt.3683  0.44
2016 Floyd BJ, Wilkerson EM, Veling MT, Minogue CE, Xia C, Beebe ET, Wrobel RL, Cho H, Kremer LS, Alston CL, Gromek KA, Dolan BK, Ulbrich A, Stefely JA, Bohl SL, ... ... Pagliarini DJ, et al. Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function. Molecular Cell. PMID 27499296 DOI: 10.1016/j.molcel.2016.06.033  0.44
2016 Stefely JA, Licitra F, Laredj L, Reidenbach AG, Kemmerer ZA, Grangeray A, Jaeg-Ehret T, Minogue CE, Ulbrich A, Hutchins PD, Wilkerson EM, Ruan Z, Aydin D, Hebert AS, Guo X, ... ... Pagliarini DJ, et al. Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity. Molecular Cell. PMID 27499294 DOI: 10.1016/j.molcel.2016.06.030  0.44
2016 Rensvold JW, Krautkramer KA, Dowell JA, Denu JM, Pagliarini DJ. Iron Deprivation Induces Transcriptional Regulation of Mitochondrial Biogenesis. The Journal of Biological Chemistry. PMID 27497435 DOI: 10.1074/jbc.M116.727701  0.4
2016 Horton JL, Martin OJ, Lai L, Riley NM, Richards AL, Vega RB, Leone TC, Pagliarini DJ, Muoio DM, Bedi KC, Margulies KB, Coon JJ, Kelly DP. Mitochondrial protein hyperacetylation in the failing heart. Jci Insight. 2. PMID 26998524 DOI: 10.1172/jci.insight.84897  0.44
2015 Tagliabracci VS, Wiley SE, Guo X, Kinch LN, Durrant E, Wen J, Xiao J, Cui J, Nguyen KB, Engel JL, Coon JJ, Grishin N, Pinna LA, Pagliarini DJ, Dixon JE. A Single Kinase Generates the Majority of the Secreted Phosphoproteome. Cell. 161: 1619-32. PMID 26091039 DOI: 10.1016/j.cell.2015.05.028  0.96
2015 Overmyer KA, Evans CR, Qi NR, Minogue CE, Carson JJ, Chermside-Scabbo CJ, Koch LG, Britton SL, Pagliarini DJ, Coon JJ, Burant CF. Maximal oxidative capacity during exercise is associated with skeletal muscle fuel selection and dynamic changes in mitochondrial protein acetylation. Cell Metabolism. 21: 468-78. PMID 25738461 DOI: 10.1016/j.cmet.2015.02.007  0.96
2015 Minogue CE, Hebert AS, Rensvold JW, Westphall MS, Pagliarini DJ, Coon JJ. Multiplexed quantification for data-independent acquisition. Analytical Chemistry. 87: 2570-5. PMID 25621425 DOI: 10.1021/ac503593d  0.96
2015 Stefely JA, Reidenbach AG, Ulbrich A, Oruganty K, Floyd BJ, Jochem A, Saunders JM, Johnson IE, Minogue CE, Wrobel RL, Barber GE, Lee D, Li S, Kannan N, Coon JJ, ... ... Pagliarini DJ, et al. Mitochondrial ADCK3 employs an atypical protein kinase-like fold to enable coenzyme Q biosynthesis. Molecular Cell. 57: 83-94. PMID 25498144 DOI: 10.1016/j.molcel.2014.11.002  0.96
2014 Lohman DC, Forouhar F, Beebe ET, Stefely MS, Minogue CE, Ulbrich A, Stefely JA, Sukumar S, Luna-Sánchez M, Jochem A, Lew S, Seetharaman J, Xiao R, Wang H, Westphall MS, ... ... Pagliarini DJ, et al. Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 111: E4697-705. PMID 25339443 DOI: 10.1073/pnas.1413128111  0.96
2014 Khadria AS, Mueller BK, Stefely JA, Tan CH, Pagliarini DJ, Senes A. A Gly-zipper motif mediates homodimerization of the transmembrane domain of the mitochondrial kinase ADCK3. Journal of the American Chemical Society. 136: 14068-77. PMID 25216398 DOI: 10.1021/ja505017f  0.96
2014 Bailey DJ, McDevitt MT, Westphall MS, Pagliarini DJ, Coon JJ. Intelligent data acquisition blends targeted and discovery methods. Journal of Proteome Research. 13: 2152-61. PMID 24611583 DOI: 10.1021/pr401278j  0.96
2014 Dingley SD, Polyak E, Ostrovsky J, Srinivasan S, Lee I, Rosenfeld AB, Tsukikawa M, Xiao R, Selak MA, Coon JJ, Hebert AS, Grimsrud PA, Kwon YJ, Pagliarini DJ, Gai X, et al. Mitochondrial DNA variant in COX1 subunit significantly alters energy metabolism of geographically divergent wild isolates in Caenorhabditis elegans. Journal of Molecular Biology. 426: 2199-216. PMID 24534730 DOI: 10.1016/j.jmb.2014.02.009  0.96
2014 Rhoads TW, Rose CM, Bailey DJ, Riley NM, Molden RC, Nestler AJ, Merrill AE, Smith LM, Hebert AS, Westphall MS, Pagliarini DJ, Garcia BA, Coon JJ. Neutron-encoded mass signatures for quantitative top-down proteomics. Analytical Chemistry. 86: 2314-9. PMID 24475910 DOI: 10.1021/ac403579s  0.96
2013 Pagliarini DJ, Rutter J. Hallmarks of a new era in mitochondrial biochemistry. Genes & Development. 27: 2615-27. PMID 24352419 DOI: 10.1101/gad.229724.113  0.96
2013 Hebert AS, Merrill AE, Stefely JA, Bailey DJ, Wenger CD, Westphall MS, Pagliarini DJ, Coon JJ. Amine-reactive neutron-encoded labels for highly plexed proteomic quantitation. Molecular & Cellular Proteomics : McP. 12: 3360-9. PMID 23882030 DOI: 10.1074/mcp.M113.032011  0.96
2013 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, ... Pagliarini DJ, et al. Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation. The Journal of Biological Chemistry. 288: 26209-19. PMID 23864654 DOI: 10.1074/jbc.M113.483396  0.44
2013 Foss MH, Eun YJ, Grove CI, Pauw DA, Sorto NA, Rensvold JW, Pagliarini DJ, Shaw JT, Weibel DB. Inhibitors of bacterial tubulin target bacterial membranes in vivo. Medchemcomm. 4: 112-119. PMID 23539337 DOI: 10.1039/C2MD20127E  0.96
2013 Hebert AS, Merrill AE, Bailey DJ, Still AJ, Westphall MS, Strieter ER, Pagliarini DJ, Coon JJ. Neutron-encoded mass signatures for multiplexed proteome quantification. Nature Methods. 10: 332-4. PMID 23435260 DOI: 10.1038/nmeth.2378  0.96
2013 Rensvold JW, Ong SE, Jeevananthan A, Carr SA, Mootha VK, Pagliarini DJ. Complementary RNA and protein profiling identifies iron as a key regulator of mitochondrial biogenesis. Cell Reports. 3: 237-45. PMID 23318259 DOI: 10.1016/j.celrep.2012.11.029  0.96
2013 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, et al. Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome. Molecular Cell. 49: 186-99. PMID 23201123 DOI: 10.1016/j.molcel.2012.10.024  0.96
2013 Vincent CE, Rensvold JW, Westphall MS, Pagliarini DJ, Coon JJ. Automated gas-phase purification for accurate, multiplexed quantification on a stand-alone ion-trap mass spectrometer. Analytical Chemistry. 85: 2079-86. PMID 23046161 DOI: 10.1021/ac302156t  0.96
2012 Grimsrud PA, Carson JJ, Hebert AS, Hubler SL, Niemi NM, Bailey DJ, Jochem A, Stapleton DS, Keller MP, Westphall MS, Yandell BS, Attie AD, Coon JJ, Pagliarini DJ. A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis. Cell Metabolism. 16: 672-83. PMID 23140645 DOI: 10.1016/j.cmet.2012.10.004  0.44
2012 Eletsky A, Jeong MY, Kim H, Lee HW, Xiao R, Pagliarini DJ, Prestegard JH, Winge DR, Montelione GT, Szyperski T. Solution NMR structure of yeast succinate dehydrogenase flavinylation factor Sdh5 reveals a putative Sdh1 binding site. Biochemistry. 51: 8475-7. PMID 23062074 DOI: 10.1021/bi301171u  0.96
2012 McAlister GC, Russell JD, Rumachik NG, Hebert AS, Syka JE, Geer LY, Westphall MS, Pagliarini DJ, Coon JJ. Analysis of the acidic proteome with negative electron-transfer dissociation mass spectrometry. Analytical Chemistry. 84: 2875-82. PMID 22335612 DOI: 10.1021/ac203430u  0.96
2010 Doughty-Shenton D, Joseph JD, Zhang J, Pagliarini DJ, Kim Y, Lu D, Dixon JE, Casey PJ. Pharmacological targeting of the mitochondrial phosphatase PTPMT1. The Journal of Pharmacology and Experimental Therapeutics. 333: 584-92. PMID 20167843 DOI: 10.1124/jpet.109.163329  0.96
2009 Calvo SE, Pagliarini DJ, Mootha VK. Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans. Proceedings of the National Academy of Sciences of the United States of America. 106: 7507-12. PMID 19372376 DOI: 10.1073/pnas.0810916106  0.96
2008 Sugiana C, Pagliarini DJ, McKenzie M, Kirby DM, Salemi R, Abu-Amero KK, Dahl HH, Hutchison WM, Vascotto KA, Smith SM, Newbold RF, Christodoulou J, Calvo S, Mootha VK, Ryan MT, et al. Mutation of C20orf7 disrupts complex I assembly and causes lethal neonatal mitochondrial disease. American Journal of Human Genetics. 83: 468-78. PMID 18940309 DOI: 10.1016/j.ajhg.2008.09.009  0.96
2008 Pagliarini DJ, Calvo SE, Chang B, Sheth SA, Vafai SB, Ong SE, Walford GA, Sugiana C, Boneh A, Chen WK, Hill DE, Vidal M, Evans JG, Thorburn DR, Carr SA, et al. A mitochondrial protein compendium elucidates complex I disease biology. Cell. 134: 112-23. PMID 18614015 DOI: 10.1016/j.cell.2008.06.016  0.96
2008 Rardin MJ, Wiley SE, Murphy AN, Pagliarini DJ, Dixon JE. Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane. The Journal of Biological Chemistry. 283: 15440-50. PMID 18385140 DOI: 10.1074/jbc.M709547200  0.96
2006 Pagliarini DJ, Dixon JE. Mitochondrial modulation: reversible phosphorylation takes center stage? Trends in Biochemical Sciences. 31: 26-34. PMID 16337125 DOI: 10.1016/j.tibs.2005.11.005  0.96
2005 Pagliarini DJ, Wiley SE, Kimple ME, Dixon JR, Kelly P, Worby CA, Casey PJ, Dixon JE. Involvement of a mitochondrial phosphatase in the regulation of ATP production and insulin secretion in pancreatic beta cells. Molecular Cell. 19: 197-207. PMID 16039589 DOI: 10.1016/j.molcel.2005.06.008  0.96
2004 Pagliarini DJ, Worby CA, Dixon JE. A PTEN-like phosphatase with a novel substrate specificity. The Journal of Biological Chemistry. 279: 38590-6. PMID 15247229 DOI: 10.1074/jbc.M404959200  0.96
2003 Merlot S, Meili R, Pagliarini DJ, Maehama T, Dixon JE, Firtel RA. A PTEN-related 5-phosphatidylinositol phosphatase localized in the Golgi. The Journal of Biological Chemistry. 278: 39866-73. PMID 12878591 DOI: 10.1074/jbc.M306318200  0.96
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