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David Gonzalez, Ph.D. - Publications

Affiliations: 
2011 Chemistry University of California, San Diego, La Jolla, CA 
Area:
Biochemistry, Chemical Biology, Mass spectrometry; Harvesting genomic information for therapeutics
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58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Vrbanac A, Patras KA, Jarmusch AK, Mills RH, Shing SR, Quinn RA, Vargas F, Gonzalez DJ, Dorrestein PC, Knight R, Nizet V. Evaluating Organism-Wide Changes in the Metabolome and Microbiome following a Single Dose of Antibiotic. Msystems. 5. PMID 33024048 DOI: 10.1128/mSystems.00340-20  0.92
2020 Wozniak JM, Mills RH, Olson J, Caldera JR, Sepich-Poore GD, Carrillo-Terrazas M, Tsai CM, Vargas F, Knight R, Dorrestein PC, Liu GY, Nizet V, Sakoulas G, Rose W, Gonzalez DJ. Mortality Risk Profiling of Staphylococcus aureus Bacteremia by Multi-omic Serum Analysis Reveals Early Predictive and Pathogenic Signatures. Cell. 182: 1311-1327.e14. PMID 32888495 DOI: 10.1016/j.cell.2020.07.040  0.92
2020 Ramirez-Sanchez I, Navarrete-Yañez V, Garate-Carrillo A, Loredo M, Lira-Romero E, Estrada-Mena J, Campeau A, Gonzalez D, Carrillo-Terrazas M, Moreno-Ulloa A, Ceballos G, Villarreal F. Development of muscle atrophy and loss of function in a Gulf-War illness model: underlying mechanisms. Scientific Reports. 10: 14526. PMID 32884027 DOI: 10.1038/s41598-020-71486-w  0.72
2020 Heckmann D, Campeau A, Lloyd CJ, Phaneuf PV, Hefner Y, Carrillo-Terrazas M, Feist AM, Gonzalez DJ, Palsson BO. Kinetic profiling of metabolic specialists demonstrates stability and consistency of in vivo enzyme turnover numbers. Proceedings of the National Academy of Sciences of the United States of America. PMID 32873645 DOI: 10.1073/pnas.2001562117  0.72
2020 Campeau A, Mills RH, Blanchette M, Bajc K, Malfavon M, Munji RN, Deng L, Hancock B, Patras KA, Olson J, Nizet V, Daneman R, Doran K, Gonzalez DJ. Multidimensional Proteome Profiling of Blood-Brain Barrier Perturbation by Group B . Msystems. 5. PMID 32843537 DOI: 10.1128/mSystems.00368-20  0.92
2020 Wozniak JM, Silva TA, Thomas D, Siqueira-Neto JL, McKerrow JH, Gonzalez DJ, Calvet CM. Molecular dissection of chagas induced cardiomyopathy reveals central disease associated and druggable signaling pathways. Plos Neglected Tropical Diseases. 14: e0007980. PMID 32433643 DOI: 10.1371/journal.pntd.0007980  0.92
2020 Rojony R, Danelishvili L, Campeau A, Wozniak JM, Gonzalez DJ, Bermudez LE. Exposure of to Environmental Stress and Clinically Used Antibiotics Reveals Common Proteome Response among Pathogenic Mycobacteria. Microorganisms. 8. PMID 32397563 DOI: 10.3390/microorganisms8050698  0.92
2020 Lin Y, Wozniak JM, Grimsey NJ, Girada S, Patwardhan A, Molinar-Inglis O, Smith TH, Lapek JD, Gonzalez DJ, Trejo J. Phosphoproteomic analysis of protease-activated receptor-1 biased signaling reveals unique modulators of endothelial barrier function. Proceedings of the National Academy of Sciences of the United States of America. PMID 32071217 DOI: 10.1073/pnas.1917295117  0.92
2020 Mills RH, Wozniak JM, Vrbanac A, Campeau A, Chassaing B, Gewirtz A, Knight R, Gonzalez DJ. Organ level protein networks as a reference for the host effects of the microbiome. Genome Research. PMID 31992612 DOI: 10.1101/gr.256875.119  0.92
2020 O'Neill AM, Nakatsuji T, Hayachi A, Williams MR, Mills RH, Gonzalez DJ, Gallo RL. Identification of a human skin commensal bacterium that selectively kills Cutibacterium acnes. The Journal of Investigative Dermatology. PMID 31981578 DOI: 10.1016/j.jid.2019.12.026  0.6
2019 Lapek JD, Jiang Z, Wozniak JM, Arutyunova E, Wang SC, Lemieux MJ, Gonzalez DJ, O'Donoghue AJ. Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry. Molecular & Cellular Proteomics : McP. 18: 968-981. PMID 33451794 DOI: 10.1074/mcp.TIR118.001099  0.92
2019 Wierzbicki IH, Campeau A, Dehaini D, Holay M, Wei X, Greene T, Ying M, Sands JS, Lamsa A, Zuniga E, Pogliano K, Fang RH, LaRock CN, Zhang L, Gonzalez DJ. Group A Streptococcal S Protein Utilizes Red Blood Cells as Immune Camouflage and Is a Critical Determinant for Immune Evasion. Cell Reports. 29: 2979-2989.e15. PMID 31801066 DOI: 10.1016/j.celrep.2019.11.001  0.72
2019 Rojony R, Martin M, Campeau A, Wozniak JM, Gonzalez DJ, Jaiswal P, Danelishvili L, Bermudez LE. Quantitative analysis of subsp proteome in response to antibiotics and during exposure to different environmental conditions. Clinical Proteomics. 16: 39. PMID 31749666 DOI: 10.1186/s12014-019-9260-2  0.92
2019 Korandla DR, Wozniak JM, Campeau A, Gonzalez DJ, Wright ES. AssessORF: combining evolutionary conservation and proteomics to assess prokaryotic gene predictions. Bioinformatics (Oxford, England). PMID 31532487 DOI: 10.1093/bioinformatics/btz714  0.92
2019 Gao NJ, Al-Bassam MM, Poudel S, Wozniak JM, Gonzalez DJ, Olson J, Zengler K, Nizet V, Valderrama JA. Functional and Proteomic Analysis of Virulence Upon Loss of Its Native Cas9 Nuclease. Frontiers in Microbiology. 10: 1967. PMID 31507572 DOI: 10.3389/fmicb.2019.01967  0.92
2019 Tran HQ, Mills RH, Peters NV, Holder MK, de Vries GJ, Knight R, Chassaing B, Gonzalez DJ, Gewirtz AT. Associations of the fecal microbial proteome composition and proneness to diet-induced obesity. Molecular & Cellular Proteomics : McP. PMID 31262998 DOI: 10.1074/mcp.RA119.001623  0.8
2019 Wozniak JM, Gonzalez DJ. : an R package for PTM site localization and motif extraction from proteomic datasets. Peerj. 7: e7046. PMID 31198645 DOI: 10.7717/peerj.7046  0.92
2019 Wei X, Ran D, Campeau A, Xiao C, Zhou J, Dehaini D, Jiang Y, Kroll AV, Zhang Q, Gao W, Gonzalez DJ, Fang RH, Zhang L. Multiantigenic Nanotoxoids for Antivirulence Vaccination against Antibiotic-Resistant Gram-Negative Bacteria. Nano Letters. PMID 31184899 DOI: 10.1021/acs.nanolett.9b01844  0.72
2019 Grainger S, Nguyen N, Richter J, Setayesh J, Lonquich B, Oon CH, Wozniak JM, Barahona R, Kamei CN, Houston J, Carrillo-Terrazas M, Drummond IA, Gonzalez D, Willert K, Traver D. EGFR is required for Wnt9a-Fzd9b signalling specificity in haematopoietic stem cells. Nature Cell Biology. PMID 31110287 DOI: 10.1038/s41556-019-0330-5  0.92
2019 Mills RH, Vázquez-Baeza Y, Zhu Q, Jiang L, Gaffney J, Humphrey G, Smarr L, Knight R, Gonzalez DJ. Evaluating Metagenomic Prediction of the Metaproteome in a 4.5-Year Study of a Patient with Crohn's Disease. Msystems. 4. PMID 30801026 DOI: 10.1128/mSystems.00337-18  0.8
2019 Quinn RA, Adem S, Mills RH, Comstock W, DeRight Goldasich L, Humphrey G, Aksenov AA, Melnik AV, da Silva R, Ackermann G, Bandeira N, Gonzalez DJ, Conrad D, O'Donoghue AJ, Knight R, et al. Neutrophilic proteolysis in the cystic fibrosis lung correlates with a pathogenic microbiome. Microbiome. 7: 23. PMID 30760325 DOI: 10.1186/s40168-019-0636-3  0.92
2019 Lapek JD, Jiang Z, Wozniak JM, Arutyunova E, Wang SC, Lemieux MJ, Gonzalez DJ, O'Donoghue AJ. Quantitative Multiplex Substrate Profiling of Peptidases by Mass Spectrometry. Molecular & Cellular Proteomics : McP. PMID 30705125 DOI: 10.1074/mcp.TIR118.001099  0.92
2019 Breuer M, Earnest TM, Merryman C, Wise KS, Sun L, Lynott MR, Hutchison CA, Smith HO, Lapek JD, Gonzalez DJ, de Crécy-Lagard V, Haas D, Hanson AD, Labhsetwar P, Glass JI, et al. Essential metabolism for a minimal cell. Elife. 8. PMID 30657448 DOI: 10.7554/eLife.36842  0.76
2018 Solomon T, Lapek JD, Jensen SB, Greenwald WW, Hindberg K, Matsui H, Latysheva N, Braekken SK, Gonzalez DJ, Frazer KA, Smith EN, Hansen JB. Identification of Common and Rare Genetic Variation Associated With Plasma Protein Levels Using Whole-Exome Sequencing and Mass Spectrometry. Circulation. Genomic and Precision Medicine. 11: e002170. PMID 30562114 DOI: 10.1161/CIRCGEN.118.002170  0.76
2018 Al-Bassam MM, Kim JN, Zaramela LS, Kellman BP, Zuniga C, Wozniak JM, Gonzalez DJ, Zengler K. Optimization of carbon and energy utilization through differential translational efficiency. Nature Communications. 9: 4474. PMID 30367068 DOI: 10.1038/s41467-018-06993-6  0.92
2018 Singh V, Yeoh BS, Chassaing B, Xiao X, Saha P, Aguilera Olvera R, Lapek JD, Zhang L, Wang WB, Hao S, Flythe MD, Gonzalez DJ, Cani PD, Conejo-Garcia JR, Xiong N, et al. Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer. Cell. 175: 679-694.e22. PMID 30340040 DOI: 10.1016/j.cell.2018.09.004  0.76
2018 Formentini L, Ryan AJ, Gálvez-Santisteban M, Carter L, Taub P, Lapek JD, Gonzalez DJ, Villarreal F, Ciaraldi TP, Cuezva JM, Henry RR. Correction to: Mitochondrial H-ATP synthase in human skeletal muscle: contribution to dyslipidaemia and insulin resistance. Diabetologia. PMID 30324489 DOI: 10.1007/s00125-018-4747-3  0.76
2018 Jensen SB, Hindberg K, Solomon T, Smith EN, Lapek JD, Gonzalez DJ, Latysheva N, Frazer KA, Braekkan SK, Hansen JB. Discovery of novel plasma biomarkers for future incident venous thromboembolism by untargeted synchronous precursor selection mass spectrometry proteomics. Journal of Thrombosis and Haemostasis : Jth. PMID 29964323 DOI: 10.1111/jth.14220  0.76
2018 Patras KA, Derieux J, Al-Bassam MM, Adiletta N, Vrbanac A, Lapek JD, Zengler K, Gonzalez DJ, Nizet V. Group B Streptococcus Biofilm Regulatory Protein A Contributes to Bacterial Physiology and Innate Immune Resistance. The Journal of Infectious Diseases. PMID 29868829 DOI: 10.1093/infdis/jiy341  0.92
2018 Lapek JD, Mills RH, Wozniak JM, Campeau A, Fang RH, Wei X, van de Groep K, Perez-Lopez A, van Sorge NM, Raffatellu M, Knight R, Zhang L, Gonzalez DJ. Defining Host Responses during Systemic Bacterial Infection through Construction of a Murine Organ Proteome Atlas. Cell Systems. PMID 29778837 DOI: 10.1016/j.cels.2018.04.010  0.92
2018 Askarian F, Lapek JD, Dongre M, Tsai CM, Kumaraswamy M, Kousha A, Valderrama JA, Ludviksen JA, Cavanagh JP, Uchiyama S, Mollnes TE, Gonzalez DJ, Wai SN, Nizet V, Johannessen M. Membrane-Derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models. Frontiers in Microbiology. 9: 262. PMID 29515544 DOI: 10.3389/fmicb.2018.00262  0.92
2018 Perera VR, Lapek JD, Newton GL, Gonzalez DJ, Pogliano K. Identification of the S-transferase like superfamily bacillithiol transferases encoded by Bacillus subtilis. Plos One. 13: e0192977. PMID 29451913 DOI: 10.1371/journal.pone.0192977  0.76
2018 Markmiller S, Soltanieh S, Server KL, Mak R, Jin W, Fang MY, Luo EC, Krach F, Yang D, Sen A, Fulzele A, Wozniak JM, Gonzalez DJ, Kankel MW, Gao FB, et al. Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules. Cell. 172: 590-604.e13. PMID 29373831 DOI: 10.1016/j.cell.2017.12.032  0.92
2017 Lapek JD, Fang RH, Wei X, Li P, Wang B, Zhang L, Gonzalez DJ. Biomimetic Virulomics for Capture and Identification of Cell-Type Specific Effector Proteins. Acs Nano. PMID 28892626 DOI: 10.1021/acsnano.7b02650  0.76
2017 Pollak AJ, Haghighi K, Kunduri S, Arvanitis DA, Bidwell PA, Liu GS, Singh VP, Gonzalez DJ, Sanoudou D, Wiley SE, Dixon JE, Kranias EG. Phosphorylation of serine96 of histidine-rich calcium-binding protein by the Fam20C kinase functions to prevent cardiac arrhythmia. Proceedings of the National Academy of Sciences of the United States of America. PMID 28784772 DOI: 10.1073/pnas.1706441114  0.92
2017 Formentini L, Ryan AJ, Gálvez-Santisteban M, Carter L, Taub P, Lapek JD, Gonzalez DJ, Villarreal F, Ciaraldi TP, Cuezva JM, Henry RR. Mitochondrial H(+)-ATP synthase in human skeletal muscle: contribution to dyslipidaemia and insulin resistance. Diabetologia. PMID 28770317 DOI: 10.1007/s00125-017-4379-z  0.76
2017 Lapek JD, Lewinski MK, Wozniak JM, Guatelli J, Gonzalez DJ. Quantitative Temporal Viromics of an Inducible HIV-1 Model Yields Insight to Global Host Targets and Phospho-Dynamics Associated with Vpr. Molecular & Cellular Proteomics : McP. PMID 28606917 DOI: 10.1074/mcp.M116.066019  0.92
2016 Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, ... ... Gonzalez DJ, et al. Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. Nature Biotechnology. 34: 828-837. PMID 27504778 DOI: 10.1038/nbt.3597  0.92
2015 Corriden R, Hollands A, Olson J, Derieux J, Lopez J, Chang JT, Gonzalez DJ, Nizet V. Tamoxifen augments the innate immune function of neutrophils through modulation of intracellular ceramide. Nature Communications. 6: 8369. PMID 26458291 DOI: 10.1038/ncomms9369  0.92
2015 Rodrigues J, Holz T, Fath Allah R, Gonzalez D, Ben T, Correia MR, Monteiro T, Costa FM. Effect of N2 and H2 plasma treatments on band edge emission of ZnO microrods. Scientific Reports. 5: 10783. PMID 26027718 DOI: 10.1038/srep10783  0.44
2015 Gonzalez D, Reyes DF, Ben T, Utrilla AD, Guzman A, Hierro A, Ulloa JM. Influence of Sb/N contents during the capping process on the morphology of InAs/GaAs quantum dots Solar Energy Materials and Solar Cells. DOI: 10.1016/j.solmat.2015.07.015  0.44
2014 Gonzalez DJ, Corriden R, Akong-Moore K, Olson J, Dorrestein PC, Nizet V. N-terminal ArgD peptides from the classical Staphylococcus aureus Agr system have cytotoxic and proinflammatory activities. Chemistry & Biology. 21: 1457-62. PMID 25457179 DOI: 10.1016/j.chembiol.2014.09.015  0.92
2014 Tagliabracci VS, Engel JL, Wiley SE, Xiao J, Gonzalez DJ, Nidumanda Appaiah H, Koller A, Nizet V, White KE, Dixon JE. Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis. Proceedings of the National Academy of Sciences of the United States of America. 111: 5520-5. PMID 24706917 DOI: 10.1073/pnas.1402218111  0.92
2014 Gonzalez DJ, Vuong L, Gonzalez IS, Keller N, McGrosso D, Hwang JH, Hung J, Zinkernagel A, Dixon JE, Dorrestein PC, Nizet V. Phenol soluble modulin (PSM) variants of community-associated methicillin-resistant Staphylococcus aureus (MRSA) captured using mass spectrometry-based molecular networking. Molecular & Cellular Proteomics : McP. 13: 1262-72. PMID 24567418 DOI: 10.1074/mcp.M113.031336  0.92
2014 Yamanaka K, Reynolds KA, Kersten RD, Ryan KS, Gonzalez DJ, Nizet V, Dorrestein PC, Moore BS. Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A. Proceedings of the National Academy of Sciences of the United States of America. 111: 1957-62. PMID 24449899 DOI: 10.1073/pnas.1319584111  0.92
2013 Kersten RD, Ziemert N, Gonzalez DJ, Duggan BM, Nizet V, Dorrestein PC, Moore BS. Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules. Proceedings of the National Academy of Sciences of the United States of America. 110: E4407-16. PMID 24191063 DOI: 10.1073/pnas.1315492110  0.92
2013 van Sorge NM, Beasley FC, Gusarov I, Gonzalez DJ, von Köckritz-Blickwede M, Anik S, Borkowski AW, Dorrestein PC, Nudler E, Nizet V. Methicillin-resistant Staphylococcus aureus bacterial nitric-oxide synthase affects antibiotic sensitivity and skin abscess development. The Journal of Biological Chemistry. 288: 6417-26. PMID 23322784 DOI: 10.1074/jbc.M112.448738  0.92
2012 Hollands A, Gonzalez D, Leire E, Donald C, Gallo RL, Sanderson-Smith M, Dorrestein PC, Nizet V. A bacterial pathogen co-opts host plasmin to resist killing by cathelicidin antimicrobial peptides. The Journal of Biological Chemistry. 287: 40891-7. PMID 23038245 DOI: 10.1074/jbc.M112.404582  0.92
2012 Gonzalez DJ, Xu Y, Yang YL, Esquenazi E, Liu WT, Edlund A, Duong T, Du L, Molnár I, Gerwick WH, Jensen PR, Fischbach M, Liaw CC, Straight P, Nizet V, et al. Observing the invisible through imaging mass spectrometry, a window into the metabolic exchange patterns of microbes. Journal of Proteomics. 75: 5069-76. PMID 22641157 DOI: 10.1016/j.jprot.2012.05.036  0.92
2012 Gonzalez DJ, Okumura CY, Hollands A, Kersten R, Akong-Moore K, Pence MA, Malone CL, Derieux J, Moore BS, Horswill AR, Dixon JE, Dorrestein PC, Nizet V. Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry. The Journal of Biological Chemistry. 287: 13889-98. PMID 22371493 DOI: 10.1074/jbc.M112.349860  0.92
2011 Gonzalez DJ, Haste NM, Hollands A, Fleming TC, Hamby M, Pogliano K, Nizet V, Dorrestein PC. Microbial competition between Bacillus subtilis and Staphylococcus aureus monitored by imaging mass spectrometry. Microbiology (Reading, England). 157: 2485-92. PMID 21719540 DOI: 10.1099/mic.0.048736-0  0.92
2011 Udwary DW, Gontang EA, Jones AC, Jones CS, Schultz AW, Winter JM, Yang JY, Beauchemin N, Capson TL, Clark BR, Esquenazi E, Eustáquio AS, Freel K, Gerwick L, Gerwick WH, ... Gonzalez D, et al. Significant natural product biosynthetic potential of actinorhizal symbionts of the genus frankia, as revealed by comparative genomic and proteomic analyses. Applied and Environmental Microbiology. 77: 3617-25. PMID 21498757 DOI: 10.1128/AEM.00038-11  0.92
2010 Gonzalez DJ, Lee SW, Hensler ME, Markley AL, Dahesh S, Mitchell DA, Bandeira N, Nizet V, Dixon JE, Dorrestein PC. Clostridiolysin S, a post-translationally modified biotoxin from Clostridium botulinum. The Journal of Biological Chemistry. 285: 28220-8. PMID 20581111 DOI: 10.1074/jbc.M110.118554  0.92
2010 He C, Nora GP, Schneider EL, Kerr ID, Hansell E, Hirata K, Gonzalez D, Sajid M, Boyd SE, Hruz P, Cobo ER, Le C, Liu WT, Eckmann L, Dorrestein PC, et al. A novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target. The Journal of Biological Chemistry. 285: 18516-27. PMID 20378535 DOI: 10.1074/jbc.M109.086181  0.92
2009 Jones AC, Gerwick L, Gonzalez D, Dorrestein PC, Gerwick WH. Transcriptional analysis of the jamaicamide gene cluster from the marine cyanobacterium Lyngbya majuscula and identification of possible regulatory proteins. Bmc Microbiology. 9: 247. PMID 19951434 DOI: 10.1186/1471-2180-9-247  0.92
2008 Esquenazi E, Coates C, Simmons L, Gonzalez D, Gerwick WH, Dorrestein PC. Visualizing the spatial distribution of secondary metabolites produced by marine cyanobacteria and sponges via MALDI-TOF imaging. Molecular Biosystems. 4: 562-70. PMID 18493654 DOI: 10.1039/b720018h  0.92
2008 Lee SW, Mitchell DA, Markley AL, Hensler ME, Gonzalez D, Wohlrab A, Dorrestein PC, Nizet V, Dixon JE. Discovery of a widely distributed toxin biosynthetic gene cluster. Proceedings of the National Academy of Sciences of the United States of America. 105: 5879-84. PMID 18375757 DOI: 10.1073/pnas.0801338105  0.92
2008 Simmons TL, Coates RC, Clark BR, Engene N, Gonzalez D, Esquenazi E, Dorrestein PC, Gerwick WH. Biosynthetic origin of natural products isolated from marine microorganism-invertebrate assemblages. Proceedings of the National Academy of Sciences of the United States of America. 105: 4587-94. PMID 18250337 DOI: 10.1073/pnas.0709851105  0.92
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