Case W. McNamara, Ph.D. - Publications

Affiliations: 
2006 University of California, San Diego, La Jolla, CA 
Area:
Mechanisms of bacterial and protozoan pathogenesis, and host response against infectious microbes

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Baragaña B, Forte B, Choi R, Nakazawa Hewitt S, Bueren-Calabuig JA, Pisco JP, Peet C, Dranow DM, Robinson DA, Jansen C, Norcross NR, Vinayak S, Anderson M, Brooks CF, Cooper CA, ... ... McNamara CW, et al. Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 30894487 DOI: 10.1073/pnas.1814685116  0.64
2018 Antonova-Koch Y, Meister S, Abraham M, Luth MR, Ottilie S, Lukens AK, Sakata-Kato T, Vanaerschot M, Owen E, Jado Rodriguez JC, Maher SP, Calla J, Plouffe D, Zhong Y, Chen K, ... ... McNamara CW, et al. Open-source discovery of chemical leads for next-generation chemoprotective antimalarials. Science (New York, N.Y.). 362. PMID 30523084 DOI: 10.1126/science.aat9446  0.64
2016 Goldgof GM, Durrant JD, Ottilie S, Vigil E, Allen KE, Gunawan F, Kostylev M, Henderson KA, Yang J, Schenken J, LaMonte GM, Manary MJ, Murao A, Nachon M, Stanhope R, ... ... McNamara CW, et al. Comparative chemical genomics reveal that the spiroindolone antimalarial KAE609 (Cipargamin) is a P-type ATPase inhibitor. Scientific Reports. 6: 27806. PMID 27291296 DOI: 10.1038/srep27806  0.64
2016 Swann J, Corey V, Scherer CA, Kato N, Comer E, Maetani M, Antonova-Koch Y, Reimer C, Gagaring K, Ibanez M, Plouffe D, Zeeman AM, Kocken CH, McNamara CW, Schreiber SL, et al. High-Throughput Luciferase-Based Assay for the Discovery of Therapeutics That Prevent Malaria. Acs Infectious Diseases. 2: 281-293. PMID 27275010 DOI: 10.1021/acsinfecdis.5b00143  0.64
2015 Khare S, Roach SL, Barnes SW, Hoepfner D, Walker JR, Chatterjee AK, Neitz RJ, Arkin MR, McNamara CW, Ballard J, Lai Y, Fu Y, Molteni V, Yeh V, McKerrow JH, et al. Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease. Plos Pathogens. 11: e1005058. PMID 26186534 DOI: 10.1371/journal.ppat.1005058  0.64
2015 Flannery EL, McNamara CW, Kim SW, Kato TS, Li F, Teng CH, Gagaring K, Manary MJ, Barboa R, Meister S, Kuhen K, Vinetz JM, Chatterjee AK, Winzeler EA. Mutations in the P-type cation-transporter ATPase 4, PfATP4, mediate resistance to both aminopyrazole and spiroindolone antimalarials. Acs Chemical Biology. 10: 413-20. PMID 25322084 DOI: 10.1021/cb500616x  0.64
2014 Manary MJ, Singhakul SS, Flannery EL, Bopp SE, Corey VC, Bright AT, McNamara CW, Walker JR, Winzeler EA. Identification of pathogen genomic variants through an integrated pipeline. Bmc Bioinformatics. 15: 63. PMID 24589256 DOI: 10.1186/1471-2105-15-63  0.64
2014 Zeeman AM, van Amsterdam SM, McNamara CW, Voorberg-van der Wel A, Klooster EJ, van den Berg A, Remarque EJ, Plouffe DM, van Gemert GJ, Luty A, Sauerwein R, Gagaring K, Borboa R, Chen Z, Kuhen K, et al. KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro. Antimicrobial Agents and Chemotherapy. 58: 1586-95. PMID 24366744 DOI: 10.1128/AAC.01927-13  0.64
2013 McNamara CW, Lee MC, Lim CS, Lim SH, Roland J, Simon O, Yeung BK, Chatterjee AK, McCormack SL, Manary MJ, Zeeman AM, Dechering KJ, Kumar TS, Henrich PP, Gagaring K, et al. Targeting Plasmodium PI(4)K to eliminate malaria. Nature. 504: 248-253. PMID 24284631 DOI: 10.1038/nature12782  0.64
2013 Spillman NJ, Allen RJ, McNamara CW, Yeung BK, Winzeler EA, Diagana TT, Kirk K. Na(+) regulation in the malaria parasite Plasmodium falciparum involves the cation ATPase PfATP4 and is a target of the spiroindolone antimalarials. Cell Host & Microbe. 13: 227-37. PMID 23414762 DOI: 10.1016/j.chom.2012.12.006  0.64
2013 Bopp SE, Manary MJ, Bright AT, Johnston GL, Dharia NV, Luna FL, McCormack S, Plouffe D, McNamara CW, Walker JR, Fidock DA, Denchi EL, Winzeler EA. Mitotic evolution of Plasmodium falciparum shows a stable core genome but recombination in antigen families. Plos Genetics. 9: e1003293. PMID 23408914 DOI: 10.1371/journal.pgen.1003293  0.64
2012 Harbut MB, Patel BA, Yeung BK, McNamara CW, Bright AT, Ballard J, Supek F, Golde TE, Winzeler EA, Diagana TT, Greenbaum DC. Targeting the ERAD pathway via inhibition of signal peptide peptidase for antiparasitic therapeutic design. Proceedings of the National Academy of Sciences of the United States of America. 109: 21486-91. PMID 23236186 DOI: 10.1073/pnas.1216016110  0.64
2012 Hoepfner D, McNamara CW, Lim CS, Studer C, Riedl R, Aust T, McCormack SL, Plouffe DM, Meister S, Schuierer S, Plikat U, Hartmann N, Staedtler F, Cotesta S, Schmitt EK, et al. Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin. Cell Host & Microbe. 11: 654-63. PMID 22704625 DOI: 10.1016/j.chom.2012.04.015  0.64
2011 Meister S, Plouffe DM, Kuhen KL, Bonamy GM, Wu T, Barnes SW, Bopp SE, Borboa R, Bright AT, Che J, Cohen S, Dharia NV, Gagaring K, Gettayacamin M, Gordon P, ... ... McNamara CW, et al. Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery. Science (New York, N.Y.). 334: 1372-7. PMID 22096101 DOI: 10.1126/science.1211936  0.64
2011 Nam TG, McNamara CW, Bopp S, Dharia NV, Meister S, Bonamy GM, Plouffe DM, Kato N, McCormack S, Bursulaya B, Ke H, Vaidya AB, Schultz PG, Winzeler EA. A chemical genomic analysis of decoquinate, a Plasmodium falciparum cytochrome b inhibitor. Acs Chemical Biology. 6: 1214-22. PMID 21866942 DOI: 10.1021/cb200105d  0.64
2009 Lauth X, von Köckritz-Blickwede M, McNamara CW, Myskowski S, Zinkernagel AS, Beall B, Ghosh P, Gallo RL, Nizet V. M1 protein allows Group A streptococcal survival in phagocyte extracellular traps through cathelicidin inhibition. Journal of Innate Immunity. 1: 202-14. PMID 20375578 DOI: 10.1159/000203645  0.64
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