Year |
Citation |
Score |
2023 |
Carucci M, Duez J, Tarning J, García-Barbazán I, Fricot-Monsinjon A, Sissoko A, Dumas L, Gamallo P, Beher B, Amireault P, Dussiot M, Dao M, Hull MV, McNamara CW, Roussel C, et al. Safe drugs with high potential to block malaria transmission revealed by a spleen-mimetic screening. Nature Communications. 14: 1951. PMID 37029122 DOI: 10.1038/s41467-023-37359-2 |
0.434 |
|
2023 |
Maher SP, Bakowski MA, Vantaux A, Flannery EL, Andolina C, Gupta M, Antonova-Koch Y, Argomaniz M, Cabrera-Mora M, Campo B, Chao AT, Chatterjee AK, Cheng WT, Cooper CA, Cottier K, ... ... McNamara CW, et al. A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Hypnozoites. Biorxiv : the Preprint Server For Biology. PMID 36778461 DOI: 10.1101/2023.01.31.526483 |
0.669 |
|
2022 |
Michaels SA, Hulverson MA, Whitman GR, Tran LT, Choi R, Fan E, McNamara CW, Love MS, Ojo KK. Repurposing the Kinase Inhibitor Mavelertinib for Giardiasis Therapy. Antimicrobial Agents and Chemotherapy. e0001722. PMID 35703552 DOI: 10.1128/aac.00017-22 |
0.304 |
|
2022 |
Ottilie S, Luth MR, Hellemann E, Goldgof GM, Vigil E, Kumar P, Cheung AL, Song M, Godinez-Macias KP, Carolino K, Yang J, Lopez G, Abraham M, Tarsio M, LeBlanc E, ... ... McNamara CW, et al. Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance. Communications Biology. 5: 128. PMID 35149760 DOI: 10.1038/s42003-022-03076-7 |
0.752 |
|
2021 |
Forte B, Ottilie S, Plater A, Campo B, Dechering KJ, Gamo FJ, Goldberg DE, Istvan ES, Lee M, Lukens AK, McNamara CW, Niles JC, Okombo J, Pasaje CFA, Siegel MG, et al. Prioritization of Molecular Targets for Antimalarial Drug Discovery. Acs Infectious Diseases. PMID 34523908 DOI: 10.1021/acsinfecdis.1c00322 |
0.55 |
|
2021 |
Bakowski MA, Beutler N, Wolff KC, Kirkpatrick MG, Chen E, Nguyen TH, Riva L, Shaabani N, Parren M, Ricketts J, Gupta AK, Pan K, Kuo P, Fuller M, Garcia E, ... ... McNamara CW, et al. Drug repurposing screens identify chemical entities for the development of COVID-19 interventions. Nature Communications. 12: 3309. PMID 34083527 DOI: 10.1038/s41467-021-23328-0 |
0.379 |
|
2021 |
Hulverson MA, Choi R, McCloskey MC, Whitman GR, Ojo KK, Michaels SA, Somepalli M, Love MS, McNamara CW, Rabago LM, Barrett LK, J Verlinde CLM, Arnold SLM, Striepen B, Jimenez-Alfaro D, et al. Repurposing Infectious Disease Hits as Anti- Leads. Acs Infectious Diseases. PMID 33740373 DOI: 10.1021/acsinfecdis.1c00076 |
0.387 |
|
2021 |
Yang T, Ottilie S, Istvan ES, Godinez-Macias KP, Lukens AK, Baragaña B, Campo B, Walpole C, Niles JC, Chibale K, Dechering KJ, Llinás M, Lee MCS, Kato N, Wyllie S, ... McNamara CW, et al. MalDA, Accelerating Malaria Drug Discovery. Trends in Parasitology. PMID 33648890 DOI: 10.1016/j.pt.2021.01.009 |
0.583 |
|
2021 |
Tyagi R, Bulman CA, Cho-Ngwa F, Fischer C, Marcellino C, Arkin MR, McKerrow JH, McNamara CW, Mahoney M, Tricoche N, Jawahar S, Janetka JW, Lustigman S, Sakanari J, Mitreva M. An Integrated Approach to Identify New Anti-Filarial Leads to Treat River Blindness, a Neglected Tropical Disease. Pathogens (Basel, Switzerland). 10. PMID 33466870 DOI: 10.3390/pathogens10010071 |
0.368 |
|
2020 |
Vinayak S, Jumani RS, Miller P, Hasan MM, McLeod BI, Tandel J, Stebbins EE, Teixeira JE, Borrel J, Gonse A, Zhang M, Yu X, Wernimont A, Walpole C, Eckley S, ... ... McNamara CW, et al. Bicyclic azetidines kill the diarrheal pathogen in mice by inhibiting parasite phenylalanyl-tRNA synthetase. Science Translational Medicine. 12. PMID 32998973 DOI: 10.1126/scitranslmed.aba8412 |
0.427 |
|
2020 |
Love MS, McNamara CW. Phenotypic screening techniques for drug discovery. Expert Opinion On Drug Discovery. 1-16. PMID 32892652 DOI: 10.1080/17460441.2020.1812577 |
0.359 |
|
2020 |
Bernatchez JA, Chen E, Hull MV, McNamara CW, McKerrow JH, Siqueira-Neto JL. High-Throughput Screening of the ReFRAME Library Identifies Potential Drug Repurposing Candidates for . Microorganisms. 8. PMID 32224991 DOI: 10.3390/microorganisms8040472 |
0.397 |
|
2020 |
Sweeney-Jones AM, Gagaring K, Antonova-Koch J, Zhou H, Mojib N, Soapi K, Skolnick J, McNamara CW, Kubanek J. Antimalarial Peptide and Polyketide Natural Products from the Fijian Marine Cyanobacterium . Marine Drugs. 18. PMID 32197482 DOI: 10.3390/Md18030167 |
0.336 |
|
2020 |
Abraham M, Gagaring K, Marino ML, Vanaerschot M, Plouffe D, Calla J, Godinez Macias K, Du A, Wree M, Antonova-Koch Y, Eribez K, Luth MR, Ottilie S, Fidock DA, McNamara C, et al. Probing the Open Global Health Chemical Diversity Library for multistage-active starting points for next-generation antimalarials. Acs Infectious Diseases. PMID 32078764 DOI: 10.1021/Acsinfecdis.9B00482 |
0.748 |
|
2020 |
Love MS, McNamara CW. High-Content Screening for Cryptosporidium Drug Discovery. Methods in Molecular Biology (Clifton, N.J.). 2052: 303-317. PMID 31452169 DOI: 10.1007/978-1-4939-9748-0_17 |
0.394 |
|
2019 |
Bakowski MA, McNamara CW. Advances in Antiwolbachial Drug Discovery for Treatment of Parasitic Filarial Worm Infections. Tropical Medicine and Infectious Disease. 4. PMID 31323841 DOI: 10.3390/tropicalmed4030108 |
0.307 |
|
2019 |
Lunde CS, Stebbins EE, Jumani RS, Hasan MM, Miller P, Barlow J, Freund YR, Berry P, Stefanakis R, Gut J, Rosenthal PJ, Love MS, McNamara CW, Easom E, Plattner JJ, et al. Identification of a potent benzoxaborole drug candidate for treating cryptosporidiosis. Nature Communications. 10: 2816. PMID 31249291 DOI: 10.1038/s41467-019-10687-y |
0.301 |
|
2019 |
Roquero I, Cantizani J, Cotillo I, Manzano MP, Kessler A, Martín JJ, McNamara CW. Novel chemical starting points for drug discovery in leishmaniasis and Chagas disease. International Journal For Parasitology. Drugs and Drug Resistance. 10: 58-68. PMID 31158574 DOI: 10.1016/j.ijpddr.2019.05.002 |
0.319 |
|
2019 |
Xu Z, Fang SM, Bakowski MA, Rateb ME, Yang D, Zhu X, Huang Y, Zhao LX, Jiang Y, Duan Y, Hull MV, McNamara CW, Shen B. Discovery of Kirromycins with Anti- Wolbachia Activity from Streptomyces sp. CB00686. Acs Chemical Biology. PMID 31074963 DOI: 10.1021/Acschembio.9B00086 |
0.361 |
|
2019 |
Jumani RS, Hasan MM, Stebbins EE, Donnelly L, Miller P, Klopfer C, Bessoff K, Teixeira JE, Love MS, McNamara CW, Huston CD. A suite of phenotypic assays to ensure pipeline diversity when prioritizing drug-like Cryptosporidium growth inhibitors. Nature Communications. 10: 1862. PMID 31015448 DOI: 10.1038/s41467-019-09880-w |
0.406 |
|
2019 |
Baragaña B, Forte B, Choi R, Nakazawa Hewitt S, Bueren-Calabuig JA, Pisco JP, Peet C, Dranow DM, Robinson DA, Jansen C, Norcross NR, Vinayak S, Anderson M, Brooks CF, Cooper CA, ... ... McNamara CW, et al. Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 30894487 DOI: 10.1073/Pnas.1814685116 |
0.667 |
|
2019 |
Jacobs RT, Lunde CS, Freund YR, Hernandez V, Li X, Xia Y, Carter DS, Berry P, Halladay J, Rock F, Stefanakis R, Easom EE, Plattner JJ, Ford L, Johnston KL, ... ... McNamara C, et al. Boron-Pleuromutilins as Anti-Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis. Journal of Medicinal Chemistry. PMID 30730745 DOI: 10.1021/Acs.Jmedchem.8B01854 |
0.397 |
|
2018 |
Antonova-Koch Y, Meister S, Abraham M, Luth MR, Ottilie S, Lukens AK, Sakata-Kato T, Vanaerschot M, Owen E, Jado Rodriguez JC, Maher SP, Calla J, Plouffe D, Zhong Y, Chen K, ... ... McNamara CW, et al. Open-source discovery of chemical leads for next-generation chemoprotective antimalarials. Science (New York, N.Y.). 362. PMID 30523084 DOI: 10.1126/Science.Aat9446 |
0.749 |
|
2018 |
Janes J, Young ME, Chen E, Rogers NH, Burgstaller-Muehlbacher S, Hughes LD, Love MS, Hull MV, Kuhen KL, Woods AK, Joseph SB, Petrassi HM, McNamara CW, Tremblay MS, Su AI, et al. The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis. Proceedings of the National Academy of Sciences of the United States of America. 115: 10750-10755. PMID 30282735 DOI: 10.1073/Pnas.1810137115 |
0.479 |
|
2018 |
Huang L, Kushner NL, Theriault ME, Pisu D, Tan S, McNamara CW, Petrassi HM, Russell DG, Brown AC. The Deconstructed Granuloma: A Complex High-Throughput Drug Screening Platform for the Discovery of Host-Directed Therapeutics Against Tuberculosis. Frontiers in Cellular and Infection Microbiology. 8: 275. PMID 30155446 DOI: 10.3389/Fcimb.2018.00275 |
0.33 |
|
2018 |
Roth A, Maher SP, Conway AJ, Ubalee R, Chaumeau V, Andolina C, Kaba SA, Vantaux A, Bakowski MA, Thomson-Luque R, Adapa SR, Singh N, Barnes SJ, Cooper CA, Rouillier M, ... McNamara CW, et al. Author Correction: A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum. Nature Communications. 9: 2317. PMID 29884783 DOI: 10.1038/S41467-018-04817-1 |
0.3 |
|
2018 |
Roth A, Maher SP, Conway AJ, Ubalee R, Chaumeau V, Andolina C, Kaba SA, Vantaux A, Bakowski MA, Luque RT, Adapa SR, Singh N, Barnes SJ, Cooper CA, Rouillier M, ... McNamara CW, et al. A comprehensive model for assessment of liver stage therapies targeting Plasmodium vivax and Plasmodium falciparum. Nature Communications. 9: 1837. PMID 29743474 DOI: 10.1038/S41467-018-04221-9 |
0.476 |
|
2018 |
Zhang G, Baidin V, Pahil KS, Moison E, Tomasek D, Ramadoss NS, Chatterjee AK, McNamara CW, Young TS, Schultz PG, Meredith TC, Kahne D. Cell-based screen for discovering lipopolysaccharide biogenesis inhibitors. Proceedings of the National Academy of Sciences of the United States of America. PMID 29735709 DOI: 10.1073/Pnas.1804670115 |
0.341 |
|
2018 |
Chen JJ, Rateb ME, Love MS, Xu Z, Yang D, Zhu X, Huang Y, Zhao LX, Jiang Y, Duan Y, McNamara CW, Shen B. Herbicidins from Streptomyces sp. CB01388 Showing Anti-Cryptosporidium Activity. Journal of Natural Products. PMID 29469575 DOI: 10.1021/Acs.Jnatprod.7B00850 |
0.4 |
|
2018 |
Jumani RS, Bessoff K, Love MS, Miller P, Stebbins EE, Teixeira JE, Campbell MA, Meyers MJ, Zambriski JA, Nunez V, Woods AK, McNamara CW, Huston CD. A Novel Piperazine-Based Drug Lead for Cryptosporidiosis from the Medicines for Malaria Venture Open Access Malaria Box. Antimicrobial Agents and Chemotherapy. PMID 29339392 DOI: 10.1128/AAC.01505-17 |
0.413 |
|
2017 |
Love MS, Beasley FC, Jumani RS, Wright TM, Chatterjee AK, Huston CD, Schultz PG, McNamara CW. A high-throughput phenotypic screen identifies clofazimine as a potential treatment for cryptosporidiosis. Plos Neglected Tropical Diseases. 11: e0005373. PMID 28158186 DOI: 10.1371/Journal.Pntd.0005373 |
0.465 |
|
2016 |
Goldgof GM, Durrant JD, Ottilie S, Vigil E, Allen KE, Gunawan F, Kostylev M, Henderson KA, Yang J, Schenken J, LaMonte GM, Manary MJ, Murao A, Nachon M, Stanhope R, ... ... McNamara CW, et al. Comparative chemical genomics reveal that the spiroindolone antimalarial KAE609 (Cipargamin) is a P-type ATPase inhibitor. Scientific Reports. 6: 27806. PMID 27291296 DOI: 10.1038/Srep27806 |
0.613 |
|
2016 |
Swann J, Corey V, Scherer CA, Kato N, Comer E, Maetani M, Antonova-Koch Y, Reimer C, Gagaring K, Ibanez M, Plouffe D, Zeeman AM, Kocken CH, McNamara CW, Schreiber SL, et al. High-Throughput Luciferase-Based Assay for the Discovery of Therapeutics That Prevent Malaria. Acs Infectious Diseases. 2: 281-293. PMID 27275010 DOI: 10.1021/Acsinfecdis.5B00143 |
0.831 |
|
2015 |
Khare S, Roach SL, Barnes SW, Hoepfner D, Walker JR, Chatterjee AK, Neitz RJ, Arkin MR, McNamara CW, Ballard J, Lai Y, Fu Y, Molteni V, Yeh V, McKerrow JH, et al. Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease. Plos Pathogens. 11: e1005058. PMID 26186534 DOI: 10.1371/Journal.Ppat.1005058 |
0.451 |
|
2015 |
Witschel MC, Rottmann M, Schwab A, Leartsakulpanich U, Chitnumsub P, Seet M, Tonazzi S, Schwertz G, Stelzer F, Mietzner T, McNamara C, Thater F, Freymond C, Jaruwat A, Pinthong C, et al. Inhibitors of plasmodial serine hydroxymethyltransferase (SHMT): cocrystal structures of pyrazolopyrans with potent blood- and liver-stage activities. Journal of Medicinal Chemistry. 58: 3117-30. PMID 25785478 DOI: 10.1021/Jm501987H |
0.472 |
|
2015 |
Flannery EL, McNamara CW, Kim SW, Kato TS, Li F, Teng CH, Gagaring K, Manary MJ, Barboa R, Meister S, Kuhen K, Vinetz JM, Chatterjee AK, Winzeler EA. Mutations in the P-type cation-transporter ATPase 4, PfATP4, mediate resistance to both aminopyrazole and spiroindolone antimalarials. Acs Chemical Biology. 10: 413-20. PMID 25322084 DOI: 10.1021/Cb500616X |
0.679 |
|
2014 |
Zou B, Nagle A, Chatterjee AK, Leong SY, Tan LJ, Sim WL, Mishra P, Guntapalli P, Tully DC, Lakshminarayana SB, Lim CS, Tan YC, Abas SN, Bodenreider C, Kuhen KL, ... ... McNamara C, et al. Lead optimization of imidazopyrazines: a new class of antimalarial with activity on Plasmodium liver stages. Acs Medicinal Chemistry Letters. 5: 947-50. PMID 25147620 DOI: 10.1021/Ml500244M |
0.666 |
|
2014 |
Manary MJ, Singhakul SS, Flannery EL, Bopp SE, Corey VC, Bright AT, McNamara CW, Walker JR, Winzeler EA. Identification of pathogen genomic variants through an integrated pipeline. Bmc Bioinformatics. 15: 63. PMID 24589256 DOI: 10.1186/1471-2105-15-63 |
0.718 |
|
2014 |
Zeeman AM, van Amsterdam SM, McNamara CW, Voorberg-van der Wel A, Klooster EJ, van den Berg A, Remarque EJ, Plouffe DM, van Gemert GJ, Luty A, Sauerwein R, Gagaring K, Borboa R, Chen Z, Kuhen K, et al. KAI407, a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro. Antimicrobial Agents and Chemotherapy. 58: 1586-95. PMID 24366744 DOI: 10.1128/Aac.01927-13 |
0.7 |
|
2013 |
McNamara CW, Lee MC, Lim CS, Lim SH, Roland J, Simon O, Yeung BK, Chatterjee AK, McCormack SL, Manary MJ, Zeeman AM, Dechering KJ, Kumar TS, Henrich PP, Gagaring K, et al. Targeting Plasmodium PI(4)K to eliminate malaria. Nature. 504: 248-253. PMID 24284631 DOI: 10.1038/Nature12782 |
0.677 |
|
2013 |
Spillman NJ, Allen RJ, McNamara CW, Yeung BK, Winzeler EA, Diagana TT, Kirk K. Na(+) regulation in the malaria parasite Plasmodium falciparum involves the cation ATPase PfATP4 and is a target of the spiroindolone antimalarials. Cell Host & Microbe. 13: 227-37. PMID 23414762 DOI: 10.1016/J.Chom.2012.12.006 |
0.608 |
|
2013 |
Bopp SE, Manary MJ, Bright AT, Johnston GL, Dharia NV, Luna FL, McCormack S, Plouffe D, McNamara CW, Walker JR, Fidock DA, Denchi EL, Winzeler EA. Mitotic evolution of Plasmodium falciparum shows a stable core genome but recombination in antigen families. Plos Genetics. 9: e1003293. PMID 23408914 DOI: 10.1371/Journal.Pgen.1003293 |
0.776 |
|
2012 |
Harbut MB, Patel BA, Yeung BK, McNamara CW, Bright AT, Ballard J, Supek F, Golde TE, Winzeler EA, Diagana TT, Greenbaum DC. Targeting the ERAD pathway via inhibition of signal peptide peptidase for antiparasitic therapeutic design. Proceedings of the National Academy of Sciences of the United States of America. 109: 21486-91. PMID 23236186 DOI: 10.1073/Pnas.1216016110 |
0.662 |
|
2012 |
Hoepfner D, McNamara CW, Lim CS, Studer C, Riedl R, Aust T, McCormack SL, Plouffe DM, Meister S, Schuierer S, Plikat U, Hartmann N, Staedtler F, Cotesta S, Schmitt EK, et al. Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin. Cell Host & Microbe. 11: 654-63. PMID 22704625 DOI: 10.1016/J.Chom.2012.04.015 |
0.695 |
|
2011 |
Meister S, Plouffe DM, Kuhen KL, Bonamy GM, Wu T, Barnes SW, Bopp SE, Borboa R, Bright AT, Che J, Cohen S, Dharia NV, Gagaring K, Gettayacamin M, Gordon P, ... ... McNamara CW, et al. Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery. Science (New York, N.Y.). 334: 1372-7. PMID 22096101 DOI: 10.1126/Science.1211936 |
0.812 |
|
2011 |
Nam TG, McNamara CW, Bopp S, Dharia NV, Meister S, Bonamy GM, Plouffe DM, Kato N, McCormack S, Bursulaya B, Ke H, Vaidya AB, Schultz PG, Winzeler EA. A chemical genomic analysis of decoquinate, a Plasmodium falciparum cytochrome b inhibitor. Acs Chemical Biology. 6: 1214-22. PMID 21866942 DOI: 10.1021/Cb200105D |
0.79 |
|
2011 |
McNamara C, Winzeler EA. Target identification and validation of novel antimalarials. Future Microbiology. 6: 693-704. PMID 21707315 DOI: 10.2217/Fmb.11.45 |
0.684 |
|
2011 |
Hanes MS, Reynolds KA, McNamara C, Ghosh P, Bonomo RA, Kirsch JF, Handel TM. Specificity and cooperativity at β-lactamase position 104 in TEM-1/BLIP and SHV-1/BLIP interactions. Proteins. 79: 1267-76. PMID 21294157 DOI: 10.1002/Prot.22961 |
0.474 |
|
2010 |
Rottmann M, McNamara C, Yeung BK, Lee MC, Zou B, Russell B, Seitz P, Plouffe DM, Dharia NV, Tan J, Cohen SB, Spencer KR, González-Páez GE, Lakshminarayana SB, Goh A, et al. Spiroindolones, a potent compound class for the treatment of malaria. Science (New York, N.Y.). 329: 1175-80. PMID 20813948 DOI: 10.1126/Science.1193225 |
0.786 |
|
2009 |
Lauth X, von Köckritz-Blickwede M, McNamara CW, Myskowski S, Zinkernagel AS, Beall B, Ghosh P, Gallo RL, Nizet V. M1 protein allows Group A streptococcal survival in phagocyte extracellular traps through cathelicidin inhibition. Journal of Innate Immunity. 1: 202-14. PMID 20375578 DOI: 10.1159/000203645 |
0.496 |
|
2008 |
Plouffe D, Brinker A, McNamara C, Henson K, Kato N, Kuhen K, Nagle A, Adrián F, Matzen JT, Anderson P, Nam TG, Gray NS, Chatterjee A, Janes J, Yan SF, et al. In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. Proceedings of the National Academy of Sciences of the United States of America. 105: 9059-64. PMID 18579783 DOI: 10.1073/Pnas.0802982105 |
0.668 |
|
2008 |
Kato N, Sakata T, Breton G, Le Roch KG, Nagle A, Andersen C, Bursulaya B, Henson K, Johnson J, Kumar KA, Marr F, Mason D, McNamara C, Plouffe D, Ramachandran V, et al. Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility. Nature Chemical Biology. 4: 347-56. PMID 18454143 DOI: 10.1038/Nchembio.87 |
0.758 |
|
2008 |
McNamara C, Zinkernagel AS, Macheboeuf P, Cunningham MW, Nizet V, Ghosh P. Coiled-coil irregularities and instabilities in group A Streptococcus M1 are required for virulence. Science (New York, N.Y.). 319: 1405-8. PMID 18323455 DOI: 10.1126/Science.1154470 |
0.455 |
|
Low-probability matches (unlikely to be authored by this person) |
2023 |
Caldwell N, Afshar R, Baragaña B, Bustinduy AL, Caffrey CR, Collins JJ, Fusco D, Garba A, Gardner M, Gomes M, Hoffmann KF, Hsieh M, Lo NC, McNamara CW, Nono JK, et al. Perspective on Schistosomiasis Drug Discovery: Highlights from a Schistosomiasis Drug Discovery Workshop at Wellcome Collection, London, September 2022. Acs Infectious Diseases. PMID 37083395 DOI: 10.1021/acsinfecdis.3c00081 |
0.282 |
|
2023 |
Yang B, Sukheja P, Qin B, Li G, Bare GAL, Cascioferro A, Love MS, Petrassi HM, Sharpless KB, McNamara CW, Chatterjee AK. Synthesis and structure-activity relationships of aryl fluorosulfate-based inhibitors as novel antitubercular agents. Bioorganic & Medicinal Chemistry Letters. 98: 129596. PMID 38142914 DOI: 10.1016/j.bmcl.2023.129596 |
0.281 |
|
2019 |
Bakowski MA, Shiroodi RK, Liu R, Olejniczak J, Yang B, Gagaring K, Guo H, White PM, Chappell L, Debec A, Landmann F, Dubben B, Lenz F, Struever D, Ehrens A, ... ... McNamara CW, et al. Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections. Science Translational Medicine. 11. PMID 31068442 DOI: 10.1126/Scitranslmed.Aav3523 |
0.279 |
|
2017 |
Hulverson MA, Choi R, L M Arnold S, Schaefer DA, Hemphill A, McCloskey MC, Betzer DP, Müller J, S R Vidadala R, Whitman GR, Rivas KL, Barrett LK, Hackman RC, Love MS, McNamara CW, et al. Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis. International Journal For Parasitology. PMID 28899690 DOI: 10.1016/J.Ijpara.2017.08.006 |
0.274 |
|
2020 |
Luna B, Trebosc V, Lee B, Bakowski M, Ulhaq A, Yan J, Lu P, Cheng J, Nielsen T, Lim J, Ketphan W, Eoh H, McNamara C, Skandalis N, She R, et al. A nutrient-limited screen unmasks rifabutin hyperactivity for extensively drug-resistant Acinetobacter baumannii. Nature Microbiology. PMID 32514072 DOI: 10.1038/S41564-020-0737-6 |
0.266 |
|
2024 |
Dayan Elshan NGR, Wolff KC, Riva L, Woods AK, Grabovyi G, Wilson K, Pedroarena J, Ghorai S, Nazarian A, Weiss F, Liu Y, Mazumdar W, Song L, Okwor N, Malvin J, ... ... McNamara CW, et al. Discovery of CMX990: A Potent SARS-CoV-2 3CL Protease Inhibitor Bearing a Novel Warhead. Journal of Medicinal Chemistry. PMID 38335279 DOI: 10.1021/acs.jmedchem.3c01938 |
0.26 |
|
2019 |
Lavoie S, Sweeney-Jones AM, Mojib N, Dale B, Gagaring K, McNamara CW, Quave CL, Soapi K, Kubanek J. Antibacterial Oligomeric Polyphenols from the Green Alga Cladophora socialis. The Journal of Organic Chemistry. PMID 30908914 DOI: 10.1021/Acs.Joc.8B03218 |
0.254 |
|
2023 |
Corman HN, McNamara CW, Bakowski MA. Drug Discovery for Cutaneous Leishmaniasis: A Review of Developments in the Past 15 Years. Microorganisms. 11. PMID 38137989 DOI: 10.3390/microorganisms11122845 |
0.25 |
|
2019 |
Khatri Chhetri B, Lavoie S, Sweeney-Jones AM, Mojib N, Raghavan V, Gagaring K, Dale B, McNamara CW, Soapi K, Quave CL, Polavarapu PL, Kubanek J. Peyssonnosides A-B, Unusual Diterpene Glycosides with a Sterically Encumbered Cyclopropane Motif: Structure Elucidation Using an Integrated Spectroscopic and Computational Workflow. The Journal of Organic Chemistry. PMID 31244158 DOI: 10.1021/Acs.Joc.9B00884 |
0.243 |
|
2019 |
Shang M, Feu KS, Vantourout JC, Barton LM, Osswald HL, Kato N, Gagaring K, McNamara CW, Chen G, Hu L, Ni S, Fernández-Canelas P, Chen M, Merchant RR, Qin T, et al. Modular, stereocontrolled C-H/C-C activation of alkyl carboxylic acids. Proceedings of the National Academy of Sciences of the United States of America. PMID 30996125 DOI: 10.1073/Pnas.1903048116 |
0.213 |
|
2023 |
Lee S, Love MS, Modukuri R, Chatterjee AK, Huerta L, Lawson AP, McNamara CW, Mead JR, Hedstrom L, Cuny GD. Structure-activity relationship of BMS906024 derivatives for Cryptosporidium parvum growth inhibition. Bioorganic & Medicinal Chemistry Letters. 129328. PMID 37196868 DOI: 10.1016/j.bmcl.2023.129328 |
0.179 |
|
2022 |
Wilburn KM, Montague CR, Qin B, Woods AK, Love MS, McNamara CW, Schultz PG, Southard TL, Huang L, Petrassi HM, VanderVen BC. Pharmacological and genetic activation of cAMP synthesis disrupts cholesterol utilization in Mycobacterium tuberculosis. Plos Pathogens. 18: e1009862. PMID 35134095 DOI: 10.1371/journal.ppat.1009862 |
0.172 |
|
2021 |
Zhang CX, Love MS, McNamara CW, Chi V, Woods AK, Joseph S, Schaefer DA, Betzer DP, Riggs MW, Iroh Tam PY, Van Voorhis WC, Arnold SLM. Pharmacokinetics and pharmacodynamics of clofazimine for treatment of cryptosporidiosis. Antimicrobial Agents and Chemotherapy. AAC0156021. PMID 34748385 DOI: 10.1128/AAC.01560-21 |
0.154 |
|
2020 |
Arnold SL, Conrad T, McNamara C, Love M, Chi V, Woods A, Joseph S, Riggs M, Schaefer D, Betzer DP, Barrett L, Van Voorhis W, Tam PI, Hermann D. Predicting the impact of infectious diarrhea pathophysiology on drug disposition The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07532 |
0.151 |
|
2021 |
Aldridge BB, Barros-Aguirre D, Barry CE, Bates RH, Berthel SJ, Boshoff HI, Chibale K, Chu XJ, Cooper CB, Dartois V, Duncan K, Fotouhi N, Gusovsky F, Hipskind PA, Kempf DJ, ... ... McNamara CW, et al. The Tuberculosis Drug Accelerator at year 10: what have we learned? Nature Medicine. PMID 34226736 DOI: 10.1038/s41591-021-01442-2 |
0.126 |
|
2019 |
Hübner MP, Gunderson E, Vogel I, Bulman CA, Lim KC, Koschel M, Ehrens A, Frohberger SJ, Fendler M, Tricoche N, Voronin D, Steven A, Chi V, Bakowski MA, Woods AK, ... ... McNamara CW, et al. Short-course quinazoline drug treatments are effective in the Litomosoides sigmodontis and Brugia pahangi jird models. International Journal For Parasitology. Drugs and Drug Resistance. 12: 18-27. PMID 31869759 DOI: 10.1016/J.Ijpddr.2019.12.001 |
0.122 |
|
1958 |
Hoerr SO, Bartlett RM, Bilton JL, Boeckman C, Brown R, Crile G, Dowlin WM, Drake JC, Elliott HB, Ellison EH, Evangelista PT, Freedlander SO, Handy RD, Hauman HL, Jones EF, ... ... McNamara CW, et al. Elective operations performed for duodenal ulcer, with their mortality. Results of a survey in selected ohio hospitals by the survey committee, Ohio chapter, American college of surgeons The American Journal of Surgery. 96: 365-368. PMID 13571510 DOI: 10.1016/0002-9610(58)90926-7 |
0.041 |
|
2020 |
Iroh Tam PY, Arnold SLM, Barrett LK, Chen CR, Conrad TM, Douglas E, Gordon MA, Hebert D, Henrion M, Hermann D, Hollingsworth B, Houpt E, Jere KC, Lindblad R, Love MS, ... ... McNamara CW, et al. Clofazimine for treatment of cryptosporidiosis in HIV-infected adults (CRYPTOFAZ): an experimental medicine, randomized, double-blind, placebo-controlled phase 2a trial. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 32277809 DOI: 10.1093/cid/ciaa421 |
0.04 |
|
1999 |
Greenier KD, Kernis MH, McNamara CW, Waschull SB, Berry AJ, Herlocker CE, Abend TA. Individual differences in reactivity to daily events: examining the roles of stability and level of self-esteem. Journal of Personality. 67: 185-208. PMID 10030023 |
0.019 |
|
2004 |
Melkani GC, McNamara C, Zardeneta G, Mendoza JA. Hydrogen peroxide induces the dissociation of GroEL into monomers that can facilitate the reactivation of oxidatively inactivated rhodanese. The International Journal of Biochemistry & Cell Biology. 36: 505-18. PMID 14687928 DOI: 10.1016/j.biocel.2003.08.012 |
0.017 |
|
2016 |
Fuller RLM, McNamara CW, Lenderking WR, Edgar C, Rylands A, Feaster T, Sabatino D, Miller DS. Establishing Equivalence of Electronic Clinician-Reported Outcome Measures Therapeutic Innovation and Regulatory Science. 50: 30-36. DOI: 10.1016/J.Jalz.2016.06.1104 |
0.013 |
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