Reza Khayat, Ph.D. - Publications

Affiliations: 
2003 Columbia University, New York, NY 
Area:
Structural Molecular Biology

39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Murin CD, Julien JP, Sok D, Stanfield RL, Khayat R, Cupo A, Moore JP, Burton DR, Wilson IA, Ward AB. Structure of 2G12 Fab2 in complex with soluble and fully glycosylated HIV-1 Env by negative-stain single-particle electron microscopy. Journal of Virology. 88: 10177-88. PMID 24965454 DOI: 10.1128/JVI.01229-14  1
2014 Veesler D, Khayat R, Krishnamurthy S, Snijder J, Huang RK, Heck AJ, Anand GS, Johnson JE. Architecture of a dsDNA viral capsid in complex with its maturation protease. Structure (London, England : 1993). 22: 230-7. PMID 24361271 DOI: 10.1016/j.str.2013.11.007  1
2013 Klasse PJ, Depetris RS, Pejchal R, Julien JP, Khayat R, Lee JH, Marozsan AJ, Cupo A, Cocco N, Korzun J, Yasmeen A, Ward AB, Wilson IA, Sanders RW, Moore JP. Influences on trimerization and aggregation of soluble, cleaved HIV-1 SOSIP envelope glycoprotein. Journal of Virology. 87: 9873-85. PMID 23824824 DOI: 10.1128/JVI.01226-13  1
2013 Khayat R, Lee JH, Julien JP, Cupo A, Klasse PJ, Sanders RW, Moore JP, Wilson IA, Ward AB. Structural characterization of cleaved, soluble HIV-1 envelope glycoprotein trimers. Journal of Virology. 87: 9865-72. PMID 23824817 DOI: 10.1128/JVI.01222-13  1
2013 Kong L, Lee JH, Doores KJ, Murin CD, Julien JP, McBride R, Liu Y, Marozsan A, Cupo A, Klasse PJ, Hoffenberg S, Caulfield M, King CR, Hua Y, Le KM, ... Khayat R, et al. Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120. Nature Structural & Molecular Biology. 20: 796-803. PMID 23708606 DOI: 10.1038/nsmb.2594  1
2013 Julien JP, Sok D, Khayat R, Lee JH, Doores KJ, Walker LM, Ramos A, Diwanji DC, Pejchal R, Cupo A, Katpally U, Depetris RS, Stanfield RL, McBride R, Marozsan AJ, et al. Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans. Plos Pathogens. 9: e1003342. PMID 23658524 DOI: 10.1371/journal.ppat.1003342  1
2012 Ekiert DC, Kashyap AK, Steel J, Rubrum A, Bhabha G, Khayat R, Lee JH, Dillon MA, O'Neil RE, Faynboym AM, Horowitz M, Horowitz L, Ward AB, Palese P, Webby R, et al. Cross-neutralization of influenza A viruses mediated by a single antibody loop. Nature. 489: 526-32. PMID 22982990 DOI: 10.1038/nature11414  1
2012 Schneemann A, Speir JA, Tan GS, Khayat R, Ekiert DC, Matsuoka Y, Wilson IA. A virus-like particle that elicits cross-reactive antibodies to the conserved stem of influenza virus hemagglutinin. Journal of Virology. 86: 11686-97. PMID 22896619 DOI: 10.1128/JVI.01694-12  1
2012 Dreyfus C, Laursen NS, Kwaks T, Zuijdgeest D, Khayat R, Ekiert DC, Lee JH, Metlagel Z, Bujny MV, Jongeneelen M, van der Vlugt R, Lamrani M, Korse HJ, Geelen E, Sahin Ö, et al. Highly conserved protective epitopes on influenza B viruses. Science (New York, N.Y.). 337: 1343-8. PMID 22878502 DOI: 10.1126/science.1222908  1
2012 Depetris RS, Julien JP, Khayat R, Lee JH, Pejchal R, Katpally U, Cocco N, Kachare M, Massi E, David KB, Cupo A, Marozsan AJ, Olson WC, Ward AB, Wilson IA, et al. Partial enzymatic deglycosylation preserves the structure of cleaved recombinant HIV-1 envelope glycoprotein trimers. The Journal of Biological Chemistry. 287: 24239-54. PMID 22645128 DOI: 10.1074/jbc.M112.371898  1
2011 McLellan JS, Pancera M, Carrico C, Gorman J, Julien JP, Khayat R, Louder R, Pejchal R, Sastry M, Dai K, O'Dell S, Patel N, Shahzad-ul-Hussan S, Yang Y, Zhang B, et al. Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature. 480: 336-43. PMID 22113616 DOI: 10.1038/nature10696  1
2011 Pejchal R, Doores KJ, Walker LM, Khayat R, Huang PS, Wang SK, Stanfield RL, Julien JP, Ramos A, Crispin M, Depetris R, Katpally U, Marozsan A, Cupo A, Maloveste S, et al. A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. Science (New York, N.Y.). 334: 1097-103. PMID 21998254 DOI: 10.1126/science.1213256  1
2011 Khayat R, Johnson JE. Pass the jelly rolls. Structure (London, England : 1993). 19: 904-6. PMID 21742257 DOI: 10.1016/j.str.2011.06.004  1
2011 Khayat R, Brunn N, Speir JA, Hardham JM, Ankenbauer RG, Schneemann A, Johnson JE. The 2.3-angstrom structure of porcine circovirus 2. Journal of Virology. 85: 7856-62. PMID 21632760 DOI: 10.1128/JVI.00737-11  1
2011 Wang K, Fu CY, Khayat R, Doerschuk PC, Johnson JE. In vivo virus structures: simultaneous classification, resolution enhancement, and noise reduction in whole-cell electron tomography. Journal of Structural Biology. 174: 425-33. PMID 21396453 DOI: 10.1016/j.jsb.2011.03.003  1
2011 Huang RK, Khayat R, Lee KK, Gertsman I, Duda RL, Hendrix RW, Johnson JE. The Prohead-I structure of bacteriophage HK97: implications for scaffold-mediated control of particle assembly and maturation. Journal of Molecular Biology. 408: 541-54. PMID 21276801 DOI: 10.1016/j.jmb.2011.01.016  1
2011 Tong L, Khayat R. Diseases caused by papillomavirus Xpharm: the Comprehensive Pharmacology Reference. 1-2. DOI: 10.1016/B978-008055232-3.60921-3  1
2011 Tong L, Khayat R. Cytomegaloviral (CMV) disease Xpharm: the Comprehensive Pharmacology Reference. 1-3. DOI: 10.1016/B978-008055232-3.60919-5  1
2011 Khayat R, Tong L. Epstein-barr virus infections Xpharm: the Comprehensive Pharmacology Reference. 1-3. DOI: 10.1016/B978-008055232-3.60916-X  1
2011 Khayat R, Tong L. Herpes simplex infections Xpharm: the Comprehensive Pharmacology Reference. 1-3. DOI: 10.1016/B978-008055232-3.60915-8  1
2011 Khayat R, Tong L. Kaposi's sarcoma Xpharm: the Comprehensive Pharmacology Reference. 1-3. DOI: 10.1016/B978-008055232-3.60834-7  1
2010 Fu CY, Wang K, Gan L, Lanman J, Khayat R, Young MJ, Jensen GJ, Doerschuk PC, Johnson JE. In vivo assembly of an archaeal virus studied with whole-cell electron cryotomography. Structure (London, England : 1993). 18: 1579-86. PMID 21134637 DOI: 10.1016/j.str.2010.10.005  1
2010 Matsui T, Lander GC, Khayat R, Johnson JE. Subunits fold at position-dependent rates during maturation of a eukaryotic RNA virus. Proceedings of the National Academy of Sciences of the United States of America. 107: 14111-5. PMID 20660783 DOI: 10.1073/pnas.1004221107  1
2010 Khayat R, Fu CY, Ortmann AC, Young MJ, Johnson JE. The architecture and chemical stability of the archaeal Sulfolobus turreted icosahedral virus. Journal of Virology. 84: 9575-83. PMID 20592081 DOI: 10.1128/JVI.00708-10  1
2010 Parent KN, Khayat R, Tu LH, Suhanovsky MM, Cortines JR, Teschke CM, Johnson JE, Baker TS. P22 coat protein structures reveal a novel mechanism for capsid maturation: stability without auxiliary proteins or chemical crosslinks. Structure (London, England : 1993). 18: 390-401. PMID 20223221 DOI: 10.1016/j.str.2009.12.014  1
2010 Khayat R, Lander GC, Johnson JE. An automated procedure for detecting protein folds from sub-nanometer resolution electron density. Journal of Structural Biology. 170: 513-21. PMID 20026407 DOI: 10.1016/j.jsb.2009.12.014  1
2009 Lander GC, Khayat R, Li R, Prevelige PE, Potter CS, Carragher B, Johnson JE. The P22 tail machine at subnanometer resolution reveals the architecture of an infection conduit. Structure (London, England : 1993). 17: 789-99. PMID 19523897 DOI: 10.1016/j.str.2009.04.006  1
2009 Banerjee M, Khayat R, Walukiewicz HE, Odegard AL, Schneemann A, Johnson JE. Dissecting the functional domains of a nonenveloped virus membrane penetration peptide. Journal of Virology. 83: 6929-33. PMID 19369344 DOI: 10.1128/JVI.02299-08  1
2009 Lawrence CM, Menon S, Eilers BJ, Bothner B, Khayat R, Douglas T, Young MJ. Structural and functional studies of archaeal viruses. The Journal of Biological Chemistry. 284: 12599-603. PMID 19158076 DOI: 10.1074/jbc.R800078200  1
2006 Maaty WS, Ortmann AC, Dlakić M, Schulstad K, Hilmer JK, Liepold L, Weidenheft B, Khayat R, Douglas T, Young MJ, Bothner B. Characterization of the archaeal thermophile Sulfolobus turreted icosahedral virus validates an evolutionary link among double-stranded DNA viruses from all domains of life. Journal of Virology. 80: 7625-35. PMID 16840341 DOI: 10.1128/JVI.00522-06  1
2006 Annedi SC, Biabani F, Poduch E, Mannargudi BM, Majumder K, Wei L, Khayat R, Tong L, Kotra LP. Engineering d-amino acid containing novel protease inhibitors using catalytic site architecture. Bioorganic & Medicinal Chemistry. 14: 214-36. PMID 16198572 DOI: 10.1016/j.bmc.2005.08.019  1
2005 Khayat R, Tang L, Larson ET, Lawrence CM, Young M, Johnson JE. Structure of an archaeal virus capsid protein reveals a common ancestry to eukaryotic and bacterial viruses. Proceedings of the National Academy of Sciences of the United States of America. 102: 18944-9. PMID 16357204 DOI: 10.1073/pnas.0506383102  1
2004 Khayat R, Batra R, Bebernitz GA, Olson MW, Tong L. Characterization of the monomer-dimer equilibrium of human cytomegalovirus protease by kinetic methods. Biochemistry. 43: 316-22. PMID 14717585 DOI: 10.1021/bi035170d  1
2003 Tao X, Khayat R, Christendat D, Savchenko A, Xu X, Goldsmith-Fischman S, Honig B, Edwards A, Arrowsmith CH, Tong L. Crystal structures of MTH1187 and its yeast ortholog YBL001c. Proteins. 52: 478-80. PMID 12866058 DOI: 10.1002/prot.10443  1
2003 Khayat R, Batra R, Qian C, Halmos T, Bailey M, Tong L. Structural and biochemical studies of inhibitor binding to human cytomegalovirus protease. Biochemistry. 42: 885-91. PMID 12549906 DOI: 10.1021/bi027045s  1
2001 Batra R, Khayat R, Tong L. Molecular mechanism for dimerization to regulate the catalytic activity of human cytomegalovirus protease. Nature Structural Biology. 8: 810-7. PMID 11524687 DOI: 10.1038/nsb0901-810  1
2001 Khayat R, Batra R, Massariol MJ, Lagacé L, Tong L. Investigating the role of histidine 157 in the catalytic activity of human cytomegalovirus protease. Biochemistry. 40: 6344-51. PMID 11371196 DOI: 10.1021/bi010158b  1
2001 Batra R, Khayat R, Tong L. Structural studies of herpesvirus proteases Protein and Peptide Letters. 8: 333-342. DOI: 10.2174/0929866013409229  1
1998 Gao-Sheridan HS, Kemper MA, Khayat R, Tilley GJ, Armstrong FA, Sridhar V, Prasad GS, Stout CD, Burgess BK. A T14C variant of Azotobacter vinelandii ferredoxin I undergoes facile [3Fe-4S]0 to [4Fe-4S]2+ conversion in vitro but not in vivo. The Journal of Biological Chemistry. 273: 33692-701. PMID 9837955 DOI: 10.1074/jbc.273.50.33692  1
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