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Brandon E. Aubol, Ph.D. - Publications

Affiliations: 
2005 University of California, San Diego, La Jolla, CA 
Area:
protein structure, dynamics and folding; 2, 3 and 4D NMR spectroscopy; PCR; equilibrium and kinetic-fluorescence, absorbance and circular dichroism spectroscopies
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Aubol BE, Adams JA. SRPK1 regulates RNA binding in a pre-spliceosomal complex using a catalytic bypass mechanism. The Febs Journal. PMID 35730996 DOI: 10.1111/febs.16560  0.462
2021 Aubol BE, Wozniak JM, Fattet L, Gonzalez DJ, Adams JA. CLK1 reorganizes the splicing factor U1-70K for early spliceosomal protein assembly. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33811140 DOI: 10.1073/pnas.2018251118  0.467
2020 Fattet L, Jung HY, Matsumoto MW, Aubol BE, Kumar A, Adams JA, Chen AC, Sah RL, Engler AJ, Pasquale EB, Yang J. Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex. Developmental Cell. PMID 32574556 DOI: 10.1016/J.Devcel.2020.05.031  0.34
2020 Aubol BE, Fattet L, Adams JA. A Conserved Sequence Motif Bridges Two Protein Kinases For Enhanced Phosphorylation and Nuclear Function of A Splicing Factor. The Febs Journal. PMID 32359191 DOI: 10.1111/Febs.15351  0.724
2020 Gou LT, Lim DH, Ma W, Aubol BE, Hao Y, Wang X, Zhao J, Liang Z, Shao C, Zhang X, Meng F, Li H, Zhang X, Xu R, Li D, et al. Initiation of Parental Genome Reprogramming in Fertilized Oocyte by Splicing Kinase SRPK1-Catalyzed Protamine Phosphorylation. Cell. PMID 32169215 DOI: 10.1016/J.Cell.2020.02.020  0.467
2019 George A, Aubol BE, Fattet L, Adams JA. Disordered protein interactions for an ordered cellular transition: Cdc-like kinase 1 is transported to the nucleus via its Ser-Arg protein substrate. The Journal of Biological Chemistry. PMID 31064840 DOI: 10.1074/Jbc.Ra119.008463  0.679
2018 Aubol BE, Serrano P, Fattet L, Wuthrich K, Adams JA. Molecular Interactions Connecting the Function of the Serine-Arginine-rich protein SRSF1 to Protein Phosphatase 1. The Journal of Biological Chemistry. PMID 30185622 DOI: 10.1074/Jbc.Ra118.004587  0.682
2018 Aubol BE, Keshwani MM, Fattet L, Adams JA. Mobilization of A Splicing Factor Through A Nuclear Kinase-Kinase Complex. The Biochemical Journal. PMID 29335301 DOI: 10.1042/Bcj20170672  0.689
2017 Aubol BE, Hailey KL, Fattet L, Jennings PA, Adams JA. Redirecting SR Protein Nuclear Trafficking Through An Allosteric Platform. Journal of Molecular Biology. PMID 28576472 DOI: 10.1016/J.Jmb.2017.05.022  0.8
2016 Aubol BE, Wu G, Keshwani MM, Movassat M, Fattet L, Hertel KJ, Fu XD, Adams JA. Release of SR Proteins from CLK1 by SRPK1: A Symbiotic Kinase System for Phosphorylation Control of Pre-mRNA Splicing. Molecular Cell. PMID 27397683 DOI: 10.1016/J.Molcel.2016.05.034  0.744
2016 Serrano P, Aubol BE, Keshwani MM, Forli S, Ma CT, Dutta SK, Geralt M, Wüthrich K, Adams JA. Directional Phosphorylation and Nuclear Transport of the Splicing Factor SRSF1 Is Regulated by an RNA Recognition Motif. Journal of Molecular Biology. 428: 2430-45. PMID 27091468 DOI: 10.1016/J.Jmb.2016.04.009  0.751
2015 Keshwani MM, Hailey KL, Aubol BE, Fattet L, McGlone ML, Jennings PA, Adams JA. Nuclear Protein Kinase CLK1 Uses A Nontraditional Docking Mechanism To Select Physiological Substrates. The Biochemical Journal. PMID 26443864 DOI: 10.1042/Bj20150903  0.818
2015 Jamros MA, Aubol BE, Keshwani MM, Zhang Z, Stamm S, Adams JA. Intra-domain Cross-talk Regulates Serine-arginine Protein Kinase 1-dependent Phosphorylation and Splicing Function of Transformer 2β1. The Journal of Biological Chemistry. 290: 17269-81. PMID 26013829 DOI: 10.1074/Jbc.M115.656579  0.775
2015 Keshwani MM, Aubol BE, Fattet L, Ma CT, Qiu J, Jennings PA, Fu XD, Adams JA. Conserved proline-directed phosphorylation regulates SR protein conformation and splicing function. The Biochemical Journal. 466: 311-22. PMID 25529026 DOI: 10.1042/Bj20141373  0.822
2014 Aubol BE, Adams JA. Recruiting a silent partner for activation of the protein kinase SRPK1. Biochemistry. 53: 4625-34. PMID 24984036 DOI: 10.1021/Bi500483M  0.709
2014 Aubol BE, Plocinik RM, Keshwani MM, McGlone ML, Hagopian JC, Ghosh G, Fu XD, Adams JA. N-terminus of the protein kinase CLK1 induces SR protein hyperphosphorylation. The Biochemical Journal. 462: 143-52. PMID 24869919 DOI: 10.1042/Bj20140494  0.772
2013 Aubol BE, Jamros MA, McGlone ML, Adams JA. Splicing kinase SRPK1 conforms to the landscape of its SR protein substrate. Biochemistry. 52: 7595-605. PMID 24074032 DOI: 10.1021/Bi4010864  0.795
2013 Aubol BE, Plocinik RM, Hagopian JC, Ma CT, McGlone ML, Bandyopadhyay R, Fu XD, Adams JA. Partitioning RS domain phosphorylation in an SR protein through the CLK and SRPK protein kinases. Journal of Molecular Biology. 425: 2894-909. PMID 23707382 DOI: 10.1016/J.Jmb.2013.05.013  0.756
2013 Zhou X, Chou TF, Aubol BE, Park CJ, Wolfenden R, Adams J, Wagner CR. Kinetic mechanism of human histidine triad nucleotide binding protein 1. Biochemistry. 52: 3588-600. PMID 23614568 DOI: 10.1021/Bi301616C  0.483
2012 Aubol BE, Plocinik RM, McGlone ML, Adams JA. Nucleotide release sequences in the protein kinase SRPK1 accelerate substrate phosphorylation. Biochemistry. 51: 6584-94. PMID 22839969 DOI: 10.1021/Bi300876H  0.769
2012 Sumanasekera C, Kelemen O, Beullens M, Aubol BE, Adams JA, Sunkara M, Morris A, Bollen M, Andreadis A, Stamm S. C6 pyridinium ceramide influences alternative pre-mRNA splicing by inhibiting protein phosphatase-1. Nucleic Acids Research. 40: 4025-39. PMID 22210893 DOI: 10.1093/Nar/Gkr1289  0.578
2011 Aubol BE, Adams JA. Applying the brakes to multisite SR protein phosphorylation: substrate-induced effects on the splicing kinase SRPK1. Biochemistry. 50: 6888-900. PMID 21728354 DOI: 10.1021/Bi2007993  0.789
2009 Buchanan SG, Hendle J, Lee PS, Smith CR, Bounaud PY, Jessen KA, Tang CM, Huser NH, Felce JD, Froning KJ, Peterman MC, Aubol BE, Gessert SF, Sauder JM, Schwinn KD, et al. SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo. Molecular Cancer Therapeutics. 8: 3181-90. PMID 19934279 DOI: 10.1158/1535-7163.Mct-09-0477  0.556
2005 Lieser SA, Aubol BE, Wong L, Jennings PA, Adams JA. Coupling phosphoryl transfer and substrate interactions in protein kinases. Biochimica Et Biophysica Acta. 1754: 191-9. PMID 16213199 DOI: 10.1016/J.Bbapap.2005.07.024  0.779
2005 Ngo JC, Chakrabarti S, Ding JH, Velazquez-Dones A, Nolen B, Aubol BE, Adams JA, Fu XD, Ghosh G. Interplay between SRPK and Clk/Sty kinases in phosphorylation of the splicing factor ASF/SF2 is regulated by a docking motif in ASF/SF2. Molecular Cell. 20: 77-89. PMID 16209947 DOI: 10.1016/J.Molcel.2005.08.025  0.748
2005 Lieser SA, Shindler C, Aubol BE, Lee S, Sun G, Adams JA. Phosphoryl transfer step in the C-terminal Src kinase controls Src recognition. The Journal of Biological Chemistry. 280: 7769-76. PMID 15623523 DOI: 10.1074/Jbc.M411736200  0.812
2004 Wong L, Lieser S, Chie-Leon B, Miyashita O, Aubol B, Shaffer J, Onuchic JN, Jennings PA, Woods VL, Adams JA. Dynamic coupling between the SH2 domain and active site of the COOH terminal Src kinase, Csk. Journal of Molecular Biology. 341: 93-106. PMID 15312765 DOI: 10.1016/J.Jmb.2004.05.060  0.759
2004 Aubol BE, Ungs L, Lukasiewicz R, Ghosh G, Adams JA. Chemical clamping allows for efficient phosphorylation of the RNA carrier protein Npl3. The Journal of Biological Chemistry. 279: 30182-8. PMID 15145958 DOI: 10.1074/Jbc.M402797200  0.694
2003 Aubol BE, Nolen B, Shaffer J, Ghosh G, Adams JA. Novel destabilization of nucleotide binding by the gamma phosphate of ATP in the yeast SR protein kinase Sky1p. Biochemistry. 42: 12813-20. PMID 14596595 DOI: 10.1021/Bi035200C  0.729
2003 Aubol BE, Chakrabarti S, Ngo J, Shaffer J, Nolen B, Fu XD, Ghosh G, Adams JA. Processive phosphorylation of alternative splicing factor/splicing factor 2. Proceedings of the National Academy of Sciences of the United States of America. 100: 12601-6. PMID 14555757 DOI: 10.1073/Pnas.1635129100  0.732
2002 Aubol BE, Nolen B, Vu D, Ghosh G, Adams JA. Mechanistic insights into Sky1p, a yeast homologue of the mammalian SR protein kinases. Biochemistry. 41: 10002-9. PMID 12146964 DOI: 10.1021/Bi020233Y  0.688
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