Andrea R. Conlan, Ph.D. - Publications

Affiliations: 
2010 Chemistry University of California, San Diego, La Jolla, CA 
Area:
protein structure, dynamics and folding; 2, 3 and 4D NMR spectroscopy; PCR; equilibrium and kinetic-fluorescence, absorbance and circular dichroism spectroscopies

12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Tamir S, Eisenberg-Domovich Y, Conlan AR, Stofleth JT, Lipper CH, Paddock ML, Mittler R, Jennings PA, Livnah O, Nechushtai R. A point mutation in the [2Fe-2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties. Acta Crystallographica. Section D, Biological Crystallography. 70: 1572-8. PMID 24914968 DOI: 10.1107/S1399004714005458  0.48
2014 Tamir S, Rotem-Bamberger S, Katz C, Morcos F, Hailey KL, Zuris JA, Wang C, Conlan AR, Lipper CH, Paddock ML, Mittler R, Onuchic JN, Jennings PA, Friedler A, Nechushtai R. Integrated strategy reveals the protein interface between cancer targets Bcl-2 and NAF-1. Proceedings of the National Academy of Sciences of the United States of America. 111: 5177-82. PMID 24706857 DOI: 10.1073/Pnas.1403770111  0.48
2013 Sohn YS, Tamir S, Song L, Michaeli D, Matouk I, Conlan AR, Harir Y, Holt SH, Shulaev V, Paddock ML, Hochberg A, Cabanchick IZ, Onuchic JN, Jennings PA, Nechushtai R, et al. NAF-1 and mitoNEET are central to human breast cancer proliferation by maintaining mitochondrial homeostasis and promoting tumor growth. Proceedings of the National Academy of Sciences of the United States of America. 110: 14676-81. PMID 23959881 DOI: 10.1073/Pnas.1313198110  0.48
2013 Tamir S, Zuris JA, Agranat L, Lipper CH, Conlan AR, Michaeli D, Harir Y, Paddock ML, Mittler R, Cabantchik ZI, Jennings PA, Nechushtai R. Nutrient-deprivation autophagy factor-1 (NAF-1): biochemical properties of a novel cellular target for anti-diabetic drugs. Plos One. 8: e61202. PMID 23717386 DOI: 10.1371/Journal.Pone.0061202  0.48
2012 Nechushtai R, Conlan AR, Harir Y, Song L, Yogev O, Eisenberg-Domovich Y, Livnah O, Michaeli D, Rosen R, Ma V, Luo Y, Zuris JA, Paddock ML, Cabantchik ZI, Jennings PA, et al. Characterization of Arabidopsis NEET reveals an ancient role for NEET proteins in iron metabolism. The Plant Cell. 24: 2139-54. PMID 22562611 DOI: 10.1105/Tpc.112.097634  0.48
2011 Zuris JA, Harir Y, Conlan AR, Shvartsman M, Michaeli D, Tamir S, Paddock ML, Onuchic JN, Mittler R, Cabantchik ZI, Jennings PA, Nechushtai R. Facile transfer of [2Fe-2S] clusters from the diabetes drug target mitoNEET to an apo-acceptor protein. Proceedings of the National Academy of Sciences of the United States of America. 108: 13047-52. PMID 21788481 DOI: 10.1073/Pnas.1109986108  0.48
2011 Conlan AR, Paddock ML, Homer C, Axelrod HL, Cohen AE, Abresch EC, Zuris JA, Nechushtai R, Jennings PA. Mutation of the His ligand in mitoNEET stabilizes the 2Fe-2S cluster despite conformational heterogeneity in the ligand environment. Acta Crystallographica. Section D, Biological Crystallography. 67: 516-23. PMID 21636891 DOI: 10.1107/S0907444911011577  0.48
2010 Zuris JA, Halim DA, Conlan AR, Abresch EC, Nechushtai R, Paddock ML, Jennings PA. Engineering the redox potential over a wide range within a new class of FeS proteins. Journal of the American Chemical Society. 132: 13120-2. PMID 20812736 DOI: 10.1021/Ja103920K  0.48
2010 Dicus MM, Conlan A, Nechushtai R, Jennings PA, Paddock ML, Britt RD, Stoll S. Binding of histidine in the (Cys)3(His)1-coordinated [2Fe-2S] cluster of human mitoNEET. Journal of the American Chemical Society. 132: 2037-49. PMID 20099820 DOI: 10.1021/Ja909359G  0.48
2009 Conlan AR, Axelrod HL, Cohen AE, Abresch EC, Zuris J, Yee D, Nechushtai R, Jennings PA, Paddock ML. Crystal structure of Miner1: The redox-active 2Fe-2S protein causative in Wolfram Syndrome 2. Journal of Molecular Biology. 392: 143-53. PMID 19580816 DOI: 10.1016/J.Jmb.2009.06.079  0.48
2009 Conlan AR, Paddock ML, Axelrod HL, Cohen AE, Abresch EC, Wiley S, Roy M, Nechushtai R, Jennings PA. The novel 2Fe-2S outer mitochondrial protein mitoNEET displays conformational flexibility in its N-terminal cytoplasmic tethering domain. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 654-9. PMID 19574633 DOI: 10.1107/S1744309109019605  0.48
2009 Tirrell TF, Paddock ML, Conlan AR, Smoll EJ, Nechushtai R, Jennings PA, Kim JE. Resonance Raman studies of the (His)(Cys)3 2Fe-2S cluster of MitoNEET: comparison to the (Cys)4 mutant and implications of the effects of pH on the labile metal center. Biochemistry. 48: 4747-52. PMID 19388667 DOI: 10.1021/Bi900028R  0.48
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