Andreas Verras, Ph.D. - Publications

Affiliations: 
2005 University of California, San Francisco, San Francisco, CA 
Area:
protein structure, mechanism, and inhibitor design

22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Imbriglio JE, Shen DM, Liang R, Marby K, You M, Youm HW, Feng Z, London C, Xiong Y, Tata J, Verras A, Garcia-Calvo M, Song X, Addona G, McLaren DG, et al. The Discovery and Pharmacology of a Novel Class of Diacylglycerol Acyltransferase 2 (DGAT2) Inhibitors. Journal of Medicinal Chemistry. PMID 26561979 DOI: 10.1021/acs.jmedchem.5b01345  1
2015 Hoyt SB, Petrilli W, London C, Liang GB, Tata J, Hu Q, Yin L, van Koppen CJ, Hartmann RW, Struthers M, Wisniewski T, Ren N, Bopp C, Sok A, Cai TQ, ... ... Verras A, et al. Discovery of Triazole CYP11B2 Inhibitors with in Vivo Activity in Rhesus Monkeys. Acs Medicinal Chemistry Letters. 6: 861-5. PMID 26288685 DOI: 10.1021/acsmedchemlett.5b00048  1
2015 Hoyt SB, Park MK, London C, Xiong Y, Tata J, Bennett DJ, Cooke A, Cai J, Carswell E, Robinson J, MacLean J, Brown L, Belshaw S, Clarkson TR, Liu K, ... ... Verras A, et al. Discovery of Benzimidazole CYP11B2 Inhibitors with in Vivo Activity in Rhesus Monkeys. Acs Medicinal Chemistry Letters. 6: 573-8. PMID 26005536 DOI: 10.1021/acsmedchemlett.5b00054  1
2014 Graham TH, Shu M, Verras A, Chen Q, Garcia-Calvo M, Li X, Lisnock J, Tong X, Tung EC, Wiltsie J, Hale JJ, Pinto S, Shen DM. Pyrazoles as non-classical bioisosteres in prolylcarboxypeptidase (PrCP) inhibitors. Bioorganic & Medicinal Chemistry Letters. 24: 1657-60. PMID 24636945 DOI: 10.1016/j.bmcl.2014.02.070  1
2014 Muise ES, Zhu Y, Verras A, Karanam BV, Gorski J, Weingarth D, Lin HV, Hwa J, Thompson JR, Hu G, Liu J, He S, DeVita RJ, Shen DM, Pinto S. Identification and characterization of sebaceous gland atrophy-sparing DGAT1 inhibitors. Plos One. 9: e88908. PMID 24558447 DOI: 10.1371/journal.pone.0088908  1
2013 Debenham JS, Graham TH, Verras A, Zhang Y, Clements MJ, Kuethe JT, Madsen-Duggan C, Liu W, Bhatt UR, Chen D, Chen Q, Garcia-Calvo M, Geissler WM, He H, Li X, et al. Discovery and optimization of orally active cyclohexane-based prolylcarboxypeptidase (PrCP) inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 6228-33. PMID 24157366 DOI: 10.1016/j.bmcl.2013.09.094  1
2012 Scalliet G, Bowler J, Luksch T, Kirchhofer-Allan L, Steinhauer D, Ward K, Niklaus M, Verras A, Csukai M, Daina A, Fonné-Pfister R. Mutagenesis and functional studies with succinate dehydrogenase inhibitors in the wheat pathogen Mycosphaerella graminicola. Plos One. 7: e35429. PMID 22536383 DOI: 10.1371/journal.pone.0035429  1
2012 Graham TH, Liu W, Verras A, Reibarkh M, Bleasby K, Bhatt UR, Chen Q, Garcia-Calvo M, Geissler WM, Gorski JN, He H, Lassman ME, Lisnock J, Li X, Shen Z, et al. A new class of prolylcarboxypeptidase inhibitors, part 2: the aminocyclopentanes. Bioorganic & Medicinal Chemistry Letters. 22: 2818-22. PMID 22444685 DOI: 10.1016/j.bmcl.2012.02.077  1
2012 Graham TH, Liu W, Verras A, Sebhat IK, Xiong Y, Bleasby K, Bhatt UR, Chen Q, Garcia-Calvo M, Geissler WM, Gorski JN, He H, Lassman ME, Lisnock J, Li X, et al. A new class of prolylcarboxypeptidase inhibitors, part 1: discovery and evaluation. Bioorganic & Medicinal Chemistry Letters. 22: 2811-7. PMID 22444683 DOI: 10.1016/j.bmcl.2012.02.075  1
2012 Wu Z, Yang C, Graham TH, Verras A, Chabin RM, Xu S, Tong X, Xie D, Lassman ME, Bhatt UR, Garcia-Calvo MM, Shen Z, Chen Q, Bleasby K, Sinharoy R, et al. Discovery of aminoheterocycles as potent and brain penetrant prolylcarboxypeptidase inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 1727-30. PMID 22290078 DOI: 10.1016/j.bmcl.2011.12.098  1
2012 Shen HC, Ding FX, Jiang J, Verras A, Chabin RM, Xu S, Tong X, Chen Q, Xie D, Lassman ME, Bhatt UR, Garcia-Calvo MM, Geissler W, Shen Z, Murphy BA, et al. Discovery of benzodihydroisofurans as novel, potent, bioavailable and brain-penetrant prolylcarboxypeptidase inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 1550-6. PMID 22264488 DOI: 10.1016/J.Bmcl.2012.01.002  1
2012 Wu Z, Yang C, Xiong Y, Feng Z, Lombardo M, Verras A, Chabin RM, Xu S, Tong X, Xie D, Lassman ME, Bhatt UR, Garcia-Calvo MM, Geissler W, Shen Z, et al. Discovery of a new class of potent prolylcarboxypeptidase inhibitors derived from alanine. Bioorganic & Medicinal Chemistry Letters. 22: 1774-8. PMID 22248857 DOI: 10.1016/j.bmcl.2011.12.064  1
2012 Graham TH, Shen HC, Liu W, Xiong Y, Verras A, Bleasby K, Bhatt UR, Chabin RM, Chen D, Chen Q, Garcia-Calvo M, Geissler WM, He H, Lassman ME, Shen Z, et al. The discovery of non-benzimidazole and brain-penetrant prolylcarboxypeptidase inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 658-65. PMID 22079761 DOI: 10.1016/J.Bmcl.2011.10.060  1
2012 Sherer EC, Verras A, Madeira M, Hagmann WK, Sheridan RP, Roberts D, Bleasby K, Cornell WD. QSAR prediction of passive permeability in the LLC-PK1 cell line: Trends in molecular properties and cross-prediction of Caco-2 permeabilities Molecular Informatics. 31: 231-245. DOI: 10.1002/minf.201100157  1
2011 Shen HC, Ding FX, Zhou C, Xiong Y, Verras A, Chabin RM, Xu S, Tong X, Xie D, Lassman ME, Bhatt UR, Garcia-Calvo MM, Geissler W, Shen Z, Chen D, et al. Discovery of benzimidazole pyrrolidinyl amides as prolylcarboxypeptidase inhibitors. Bioorganic & Medicinal Chemistry Letters. 21: 1299-305. PMID 21315588 DOI: 10.1016/J.Bmcl.2011.01.090  1
2011 Cernak T, Dykstra K, Levorse D, Verras A, Balkovec J, Nargund R, DeVita R. Synthesis of oxaspiropiperidines as a strategy for lowering logD Tetrahedron Letters. 52: 6457-6459. DOI: 10.1016/j.tetlet.2011.09.100  1
2010 Zhao X, Southwick K, Cardasis HL, Du Y, Lassman ME, Xie D, El-Sherbeini M, Geissler WM, Pryor KD, Verras A, Garcia-Calvo M, Shen DM, Yates NA, Pinto S, Hendrickon RC. Peptidomic profiling of human cerebrospinal fluid identifies YPRPIHPA as a novel substrate for prolylcarboxypeptidase. Proteomics. 10: 2882-6. PMID 20517885 DOI: 10.1002/pmic.201000145  1
2006 Verras A, Ortiz de Montellano PR. Protein dynamics and imidazole binding in cytochrome P450 enzymes. Biochemical Society Transactions. 34: 1170-2. PMID 17073778 DOI: 10.1042/Bst0341170  1
2006 Verras A, Alian A, Ortiz De Montellano PR. Cytochrome P450 active site plasticity: Attenuation of imidazole binding in cytochrome P450cam by an L244A mutation Protein Engineering, Design and Selection. 19: 491-496. PMID 16943206 DOI: 10.1093/Protein/Gzl035  1
2006 Verras A, Kuntz ID, Ortiz de Montellano PR. Chapter 10 Cytochrome P450 Enzymes: Computational Approaches to Substrate Prediction Annual Reports in Computational Chemistry. 2: 171-195. DOI: 10.1016/S1574-1400(06)02010-X  1
2004 Verras A, Kuntz ID, Ortiz de Montellano PR. Computer-assisted design of selective imidazole inhibitors for cytochrome p450 enzymes. Journal of Medicinal Chemistry. 47: 3572-9. PMID 15214784 DOI: 10.1021/Jm030608T  1
1995 Sgoutas DS, Tuten TE, Verras AA, Love A, Barton EG. AquaLite bioluminescence assay of thyrotropin in serum evaluated. Clinical Chemistry. 41: 1637-43. PMID 7586555  1
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