Miklos Guttman, Ph.D. - Publications

2009 Chemistry University of California, San Diego, La Jolla, CA 
Structure, function, dynamics and thermodynamics of protein-protein interactions: NMR, mass spectrometry and kinetics

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Mookherjee A, Uppal SS, Murphree TA, Guttman M. Linkage Memory in Underivatized Protonated Carbohydrates. Journal of the American Society For Mass Spectrometry. PMID 33350817 DOI: 10.1021/jasms.0c00440  1
2020 Watson MJ, Harkewicz R, Hodge EA, Vorauer C, Palmer J, Lee KK, Guttman M. Simple Platform for Automating Decoupled LC-MS Analysis of Hydrogen/Deuterium Exchange Samples. Journal of the American Society For Mass Spectrometry. PMID 33284630 DOI: 10.1021/jasms.0c00341  0.52
2020 Alonge K, Harkewicz R, Guttman M. Rapid differentiation of chondroitin sulfate isomers by gas-phase hydrogen/deuterium exchange. Current Molecular Medicine. PMID 32933460 DOI: 10.2174/1566524020666200915110707  0.52
2020 Guttman M, Padte NN, Huang Y, Yu J, Rocklin GJ, Weitzner BD, Scian M, Ho DD, Lee KK. The influence of proline isomerization on potency and stability of anti-HIV antibody 10E8. Scientific Reports. 10: 14313. PMID 32868832 DOI: 10.1038/s41598-020-71184-7  0.56
2020 Silzel JW, Murphree TA, Paranji RK, Guttman MM, Julian RR. Probing the Stability of Proline Cis/Trans Isomers in the Gas Phase with Ultraviolet Photodissociation. Journal of the American Society For Mass Spectrometry. PMID 32808771 DOI: 10.1021/jasms.0c00242  0.8
2020 Murphree TA, Vorauer C, Brzoska M, Guttman M. Imidazolium Compounds as Internal Exchange Reporters for Hydrogen/Deuterium Exchange by Mass Spectrometry. Analytical Chemistry. PMID 32569457 DOI: 10.1021/acs.analchem.0c01328  0.8
2020 Uppal SS, Mookherjee A, Harkewicz R, Beasley SE, Bush MF, Guttman M. High-Precision, Gas-Phase Hydrogen/Deuterium Exchange Kinetics by Mass Spectrometry Enabled by Exchange Standards. Analytical Chemistry. PMID 32368904 DOI: 10.1021/acs.analchem.0c00749  1
2019 Kowalski JP, McDonald MG, Whittington D, Guttman M, Scian M, Girhard M, Hanenberg H, Wiek C, Rettie AE. Structure-Activity Relationships for CYP4B1 Bioactivation of 4-Ipomeanol Congeners: Direct Correlation between Cytotoxicity and Trapped Reactive Intermediates. Chemical Research in Toxicology. PMID 31799839 DOI: 10.1021/acs.chemrestox.9b00330  0.56
2019 Alonge KM, Logsdon AF, Murphree TA, Banks WA, Keene CD, Edgar JS, Whittington D, Schwartz MW, Guttman M. Quantitative analysis of chondroitin sulfate disaccharides from human and rodent fixed brain tissue by electrospray ionization-tandem mass spectrometry. Glycobiology. PMID 31361007 DOI: 10.1093/glycob/cwz060  0.8
2018 Mookherjee A, Uppal SS, Guttman M. Dissection of Fragmentation Pathways in Protonated N-acetylhexosamines. Analytical Chemistry. PMID 30216047 DOI: 10.1021/acs.analchem.8b01963  1
2018 Li MJ, Guttman M, Atkins WM. Conformational dynamics of P-glycoprotein in lipid nanodiscs and detergent micelles reveal complex motions on a wide time scale. The Journal of Biological Chemistry. PMID 29511086 DOI: 10.1074/jbc.RA118.002190  0.4
2017 Uppal SS, Beasley SE, Scian M, Guttman M. Gas-phase hydrogen/deuterium exchange for distinguishing isomeric carbohydrate ions. Analytical Chemistry. PMID 28304155 DOI: 10.1021/acs.analchem.7b00683  1
2016 Scian M, Guttman M, Bouldin SD, Outten CE, Atkins WM. The Myeloablative Drug Busulfan Converts Cysteine to Dehydro-alanine and Lanthionine in Redoxins. Biochemistry. PMID 27490699 DOI: 10.1021/acs.biochem.6b00622  0.56
2016 Joyce MG, Zhang B, Ou L, Chen M, Chuang GY, Druz A, Kong WP, Lai YT, Rundlet EJ, Tsybovsky Y, Yang Y, Georgiev IS, Guttman M, Lees CR, Pancera M, et al. Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV. Nature Structural & Molecular Biology. PMID 27478931 DOI: 10.1038/nsmb.3267  0.96
2016 Davenport TM, Gorman J, Joyce MG, Zhou T, Soto C, Guttman M, Moquin S, Yang Y, Zhang B, Doria-Rose NA, Hu SL, Mascola JR, Kwong PD, Lee KK. Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies. Structure (London, England : 1993). PMID 27477385 DOI: 10.1016/j.str.2016.06.012  0.96
2016 Guttman M, Lee KK. Site-specific mapping of sialic acid linkage isomers by ion mobility spectrometry. Analytical Chemistry. PMID 27089023 DOI: 10.1021/acs.analchem.6b00265  0.96
2016 Liang Y, Guttman M, Davenport TM, Hu SL, Lee KK. Probing the impact of local structural dynamics of conformational epitopes on antibody recognition. Biochemistry. PMID 27003615 DOI: 10.1021/acs.biochem.5b01354  0.96
2016 Treuheit NA, Redhair M, Kwon H, McClary WD, Guttman M, Sumida JP, Atkins WM. Membrane Interactions, Ligand-dependent Dynamics, and Stability of Cytochrome P4503A4 in Lipid Nanodiscs. Biochemistry. PMID 26814638 DOI: 10.1021/acs.biochem.5b01313  0.96
2016 Guttman M, Wales TE, Whittington D, Engen JR, Brown JM, Lee KK. Tuning a High Transmission Ion Guide to Prevent Gas-Phase Proton Exchange During H/D Exchange MS Analysis. Journal of the American Society For Mass Spectrometry. PMID 26810432 DOI: 10.1007/s13361-015-1330-8  0.96
2015 Gorman J, Soto C, Yang MM, Davenport TM, Guttman M, Bailer RT, Chambers M, Chuang GY, DeKosky BJ, Doria-Rose NA, Druz A, Ernandes MJ, Georgiev IS, Jarosinski MC, Joyce MG, et al. Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design. Nature Structural & Molecular Biology. PMID 26689967 DOI: 10.1038/nsmb.3144  0.96
2015 de Taeye SW, Ozorowski G, Torrents de la Peña A, Guttman M, Julien JP, van den Kerkhof TL, Burger JA, Pritchard LK, Pugach P, Yasmeen A, Crampton J, Hu J, Bontjer I, Torres JL, Arendt H, et al. Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes. Cell. 163: 1702-15. PMID 26687358 DOI: 10.1016/j.cell.2015.11.056  0.96
2015 Gupta S, Guttman M, Leverenz RL, Zhumadilova K, Pawlowski EG, Petzold CJ, Lee KK, Ralston CY, Kerfeld CA. Local and global structural drivers for the photoactivation of the orange carotenoid protein. Proceedings of the National Academy of Sciences of the United States of America. PMID 26385969 DOI: 10.1073/pnas.1512240112  0.96
2015 Ringe RP, Yasmeen A, Ozorowski G, Go EP, Pritchard LK, Guttman M, Ketas TA, Cottrell CA, Wilson IA, Sanders RW, Cupo A, Crispin M, Lee KK, Desaire H, Ward AB, et al. Influences on the design and purification of soluble, recombinant native-like HIV-1 envelope glycoprotein trimers. Journal of Virology. PMID 26311893 DOI: 10.1128/JVI.01768-15  0.96
2015 Do Kwon Y, Pancera M, Acharya P, Georgiev IS, Crooks ET, Gorman J, Joyce MG, Guttman M, Ma X, Narpala S, Soto C, Terry DS, Yang Y, Zhou T, Ahlsen G, et al. Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env. Nature Structural & Molecular Biology. 22: 522-31. PMID 26098315 DOI: 10.1038/nsmb.3051  0.96
2015 Sanders RW, van Gils MJ, Derking R, Sok D, Ketas TJ, Burger JA, Ozorowski G, Cupo A, Simonich C, Goo L, Arendt H, Kim HJ, Lee JH, Pugach P, Williams M, ... ... Guttman M, et al. HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers. Science (New York, N.Y.). 349: aac4223. PMID 26089353 DOI: 10.1126/science.aac4223  0.96
2015 Guttman M, Váradi C, Lee KK, Guttman A. Comparative glycoprofiling of HIV gp120 immunogens by capillary electrophoresis and MALDI mass spectrometry. Electrophoresis. 36: 1305-13. PMID 25809283 DOI: 10.1002/elps.201500054  0.96
2015 Garcia NK, Guttman M, Ebner JL, Lee KK. Dynamic changes during acid-induced activation of influenza hemagglutinin. Structure (London, England : 1993). 23: 665-76. PMID 25773144 DOI: 10.1016/j.str.2015.02.006  0.96
2015 Guttman M, Cupo A, Julien JP, Sanders RW, Wilson IA, Moore JP, Lee KK. Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env. Nature Communications. 6: 6144. PMID 25652336 DOI: 10.1038/ncomms7144  0.96
2015 Guttman M, Lee KK. Isotope Labeling of Biomolecules: Structural Analysis of Viruses by HDX-MS Methods in Enzymology. DOI: 10.1016/bs.mie.2015.05.021  0.96
2014 Guttman M, Garcia NK, Cupo A, Matsui T, Julien JP, Sanders RW, Wilson IA, Moore JP, Lee KK. CD4-induced activation in a soluble HIV-1 Env trimer. Structure (London, England : 1993). 22: 974-84. PMID 24931470 DOI: 10.1016/j.str.2014.05.001  0.96
2013 Guttman M, Weis DD, Engen JR, Lee KK. Analysis of overlapped and noisy hydrogen/deuterium exchange mass spectra. Journal of the American Society For Mass Spectrometry. 24: 1906-12. PMID 24018862 DOI: 10.1007/s13361-013-0727-5  0.96
2013 Guttman M, Lee KK. A functional interaction between gp41 and gp120 is observed for monomeric but not oligomeric, uncleaved HIV-1 Env gp140. Journal of Virology. 87: 11462-75. PMID 23966389 DOI: 10.1128/JVI.01681-13  0.96
2013 Davenport TM, Guttman M, Guo W, Cleveland B, Kahn M, Hu SL, Lee KK. Isolate-specific differences in the conformational dynamics and antigenicity of HIV-1 gp120. Journal of Virology. 87: 10855-73. PMID 23903848 DOI: 10.1128/JVI.01535-13  0.96
2013 Guttman M, Weinkam P, Sali A, Lee KK. All-atom ensemble modeling to analyze small-angle x-ray scattering of glycosylated proteins. Structure (London, England : 1993). 21: 321-31. PMID 23473666 DOI: 10.1016/j.str.2013.02.004  0.96
2012 Guttman M, Kahn M, Garcia NK, Hu SL, Lee KK. Solution structure, conformational dynamics, and CD4-induced activation in full-length, glycosylated, monomeric HIV gp120. Journal of Virology. 86: 8750-64. PMID 22674993 DOI: 10.1128/JVI.07224-11  0.96
2011 Guttman M, Komives EA. The structure, dynamics, and binding of the LA45 module pair of the low-density lipoprotein receptor suggest an important role for LA4 in ligand release. Biochemistry. 50: 11001-8. PMID 22091758 DOI: 10.1021/bi2014486  0.96
2011 Guttman M, Scian M, Lee KK. Tracking hydrogen/deuterium exchange at glycan sites in glycoproteins by mass spectrometry. Analytical Chemistry. 83: 7492-9. PMID 21863800 DOI: 10.1021/ac201729v  0.96
2011 Mulvihill MM, Guttman M, Komives EA. Protein interactions among Fe65, the low-density lipoprotein receptor-related protein, and the amyloid precursor protein. Biochemistry. 50: 6208-16. PMID 21650223 DOI: 10.1021/bi200508f  0.96
2010 Guttman M, Prieto JH, Handel TM, Domaille PJ, Komives EA. Structure of the minimal interface between ApoE and LRP. Journal of Molecular Biology. 398: 306-19. PMID 20303980 DOI: 10.1016/j.jmb.2010.03.022  0.96
2010 Guttman M, Prieto JH, Croy JE, Komives EA. Decoding of lipoprotein-receptor interactions: properties of ligand binding modules governing interactions with apolipoprotein E. Biochemistry. 49: 1207-16. PMID 20030366 DOI: 10.1021/bi9017208  0.96
2009 Guttman M, Betts GN, Barnes H, Ghassemian M, van der Geer P, Komives EA. Interactions of the NPXY microdomains of the low density lipoprotein receptor-related protein 1. Proteomics. 9: 5016-28. PMID 19771558 DOI: 10.1002/pmic.200900457  0.96
2009 Gertsman I, Gan L, Guttman M, Lee K, Speir JA, Duda RL, Hendrix RW, Komives EA, Johnson JE. An unexpected twist in viral capsid maturation. Nature. 458: 646-50. PMID 19204733 DOI: 10.1038/nature07686  0.96
2003 Guttman M, Fules P, Guttman A. Analysis of site-directed mutagenesis constructs by capillary electrophoresis using linear polymer sieving matrices. Journal of Chromatography. A. 1014: 21-7. PMID 14558608 DOI: 10.1016/S0021-9673(03)00851-3  0.96
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