☰

Lei Stanley Qi, Ph.D. - Publications

Affiliations: 
Stanford University, Palo Alto, CA 
 2012 Bioengineering University of California, Berkeley, Berkeley, CA, United States 
Area:
Bioengineering, Chemical and Systems Biology
Tree Info Similar researchers PubMed Report error

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Liu P, Foiret J, Situ Y, Zhang N, Kare AJ, Wu B, Raie MN, Ferrara KW, Qi LS. Sonogenetic control of multiplexed genome regulation and base editing. Nature Communications. 14: 6575. PMID 37852951 DOI: 10.1038/s41467-023-42249-8  0.314
2023 Chang HY, Qi LS. Reversing the Central Dogma: RNA-guided control of DNA in epigenetics and genome editing. Molecular Cell. 83: 442-451. PMID 36736311 DOI: 10.1016/j.molcel.2023.01.010  0.329
2022 Chavez M, Chen X, Finn PB, Qi LS. Advances in CRISPR therapeutics. Nature Reviews. Nephrology. PMID 36280707 DOI: 10.1038/s41581-022-00636-2  0.311
2022 Guo LY, Bian J, Davis AE, Liu P, Kempton HR, Zhang X, Chemparathy A, Gu B, Lin X, Rane DA, Xu X, Jamiolkowski RM, Hu Y, Wang S, Qi LS. Multiplexed genome regulation in vivo with hyper-efficient Cas12a. Nature Cell Biology. PMID 35414015 DOI: 10.1038/s41556-022-00870-7  0.307
2022 Nishiga M, Liu C, Qi LS, Wu JC. The use of new CRISPR tools in cardiovascular research and medicine. Nature Reviews. Cardiology. PMID 35145236 DOI: 10.1038/s41569-021-00669-3  0.307
2021 Xu X, Chemparathy A, Zeng L, Kempton HR, Shang S, Nakamura M, Qi LS. Engineered miniature CRISPR-Cas system for mammalian genome regulation and editing. Molecular Cell. PMID 34480847 DOI: 10.1016/j.molcel.2021.08.008  0.309
2021 Qi LS, Larson MH, Gilbert LA, Doudna JA, Weissman JS, Arkin AP, Lim WA. Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell. 184: 844. PMID 33545038 DOI: 10.1016/j.cell.2021.01.019  0.523
2020 Brower KK, Khariton M, Suzuki PH, Still C, Kim G, Calhoun SGK, Qi LS, Wang B, Fordyce PM. Double Emulsion Picoreactors for High-Throughput Single-Cell Encapsulation and Phenotyping via FACS. Analytical Chemistry. PMID 32900183 DOI: 10.1021/Acs.Analchem.0C02499  0.326
2020 Abbott TR, Dhamdhere G, Liu Y, Lin X, Goudy L, Zeng L, Chemparathy A, Chmura S, Heaton NS, Debs R, Pande T, Endy D, La Russa MF, Lewis DB, Qi LS. Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza. Cell. PMID 32353252 DOI: 10.1016/J.Cell.2020.04.020  0.325
2020 Nishiga M, Qi LS, Wu JC. Therapeutic genome editing in cardiovascular diseases. Advanced Drug Delivery Reviews. PMID 32092381 DOI: 10.1016/J.Addr.2020.02.003  0.317
2020 Kempton HR, Goudy LE, Love KS, Qi LS. Multiple Input Sensing and Signal Integration Using a Split Cas12a System. Molecular Cell. PMID 32027839 DOI: 10.1016/J.Molcel.2020.01.016  0.352
2019 Wang H, Nakamura M, Abbott TR, Zhao D, Luo K, Yu C, Nguyen CM, Lo A, Daley TP, La Russa M, Liu Y, Qi LS. CRISPR-mediated live imaging of genome editing and transcription. Science (New York, N.Y.). PMID 31488703 DOI: 10.1126/Science.Aax7852  0.734
2019 Li J, Zhang B, Zhou L, Qi L, Yue L, Zhang W, Cheng H, Whitman WB, Dong X. The archaeal RNA chaperone TRAM0076 shapes the transcriptome and optimizes the growth of Methanococcus maripaludis. Plos Genetics. 15: e1008328. PMID 31404065 DOI: 10.1371/Journal.Pgen.1008328  0.345
2019 Shariati SA, Dominguez A, Xie S, Wernig M, Qi LS, Skotheim JM. Reversible Disruption of Specific Transcription Factor-DNA Interactions Using CRISPR/Cas9. Molecular Cell. 74: 622-633.e4. PMID 31051141 DOI: 10.1016/J.Molcel.2019.04.011  0.329
2019 Kempton HR, Qi LS. When genome editing goes off-target. Science (New York, N.Y.). 364: 234-236. PMID 31000651 DOI: 10.1126/Science.Aax1827  0.301
2019 Shortt K, Heruth DP, Zhang N, Wu W, Singh S, Li DY, Zhang LQ, Wyckoff GJ, Qi LS, Friesen CA, Ye SQ. Identification of Novel Regulatory Genes in APAP Induced Hepatocyte Toxicity by a Genome-Wide CRISPR-Cas9 Screen. Scientific Reports. 9: 1396. PMID 30718897 DOI: 10.1038/S41598-018-37940-6  0.347
2019 Nakamura M, Srinivasan P, Chavez M, Carter MA, Dominguez AA, La Russa M, Lau MB, Abbott TR, Xu X, Zhao D, Gao Y, Kipniss NH, Smolke CD, Bondy-Denomy J, Qi LS. Anti-CRISPR-mediated control of gene editing and synthetic circuits in eukaryotic cells. Nature Communications. 10: 194. PMID 30643127 DOI: 10.1038/S41467-018-08158-X  0.402
2018 Liu Y, Yu C, Daley TP, Wang F, Cao WS, Bhate S, Lin X, Still C, Liu H, Zhao D, Wang H, Xie XS, Ding S, Wong WH, Wernig M, ... Qi LS, et al. CRISPR Activation Screens Systematically Identify Factors that Drive Neuronal Fate and Reprogramming. Cell Stem Cell. PMID 30318302 DOI: 10.1016/J.Stem.2018.09.003  0.301
2018 Wang H, Xu X, Nguyen CM, Liu Y, Gao Y, Lin X, Daley T, Kipniss NH, La Russa M, Qi LS. CRISPR-Mediated Programmable 3D Genome Positioning and Nuclear Organization. Cell. PMID 30318144 DOI: 10.1016/J.Cell.2018.09.013  0.371
2018 Xu X, Qi LS. A CRISPR-dCas Toolbox for Genetic Engineering and Synthetic Biology. Journal of Molecular Biology. PMID 29958882 DOI: 10.1016/J.Jmb.2018.06.037  0.433
2018 Liu P, Chen M, Liu Y, Qi LS, Ding S. CRISPR-Based Chromatin Remodeling of the Endogenous Oct4 or Sox2 Locus Enables Reprogramming to Pluripotency. Cell Stem Cell. PMID 29358044 DOI: 10.1016/J.Stem.2017.12.001  0.337
2017 Kipniss NH, Dingal PCDP, Abbott TR, Gao Y, Wang H, Dominguez AA, Labanieh L, Qi LS. Engineering cell sensing and responses using a GPCR-coupled CRISPR-Cas system. Nature Communications. 8: 2212. PMID 29263378 DOI: 10.1038/S41467-017-02075-1  0.361
2017 Zhou XX, Zou X, Chung HK, Gao Y, Liu Y, Qi LS, Lin MZ. A single-chain photoswitchable CRISPR-Cas9 architecture for light-inducible gene editing and transcription. Acs Chemical Biology. PMID 28938067 DOI: 10.1021/Acschembio.7B00603  0.364
2017 Zhang B, Yue L, Zhou L, Qi L, Li J, Dong X. Conserved TRAM Domain Functions as an Archaeal Cold Shock Protein via RNA Chaperone Activity. Frontiers in Microbiology. 8: 1597. PMID 28878753 DOI: 10.3389/fmicb.2017.01597  0.311
2017 Lo A, Qi L. Genetic and epigenetic control of gene expression by CRISPR-Cas systems. F1000research. 6. PMID 28649363 DOI: 10.12688/F1000Research.11113.1  0.399
2017 Chen M, Qi LS. Repurposing CRISPR System for Transcriptional Activation. Advances in Experimental Medicine and Biology. 983: 147-157. PMID 28639197 DOI: 10.1007/978-981-10-4310-9_10  0.34
2017 Du D, Roguev A, Gordon DE, Chen M, Chen SH, Shales M, Shen JP, Ideker T, Mali P, Qi LS, Krogan NJ. Genetic interaction mapping in mammalian cells using CRISPR interference. Nature Methods. PMID 28481362 DOI: 10.1038/Nmeth.4286  0.378
2017 Takei Y, Shah S, Harvey S, Qi LS, Cai L. Multiplexed Dynamic Imaging of Genomic Loci by Combined CRISPR Imaging and DNA Sequential FISH. Biophysical Journal. PMID 28427715 DOI: 10.1016/J.Bpj.2017.03.024  0.31
2017 Shen JP, Zhao D, Sasik R, Luebeck J, Birmingham A, Bojorquez-Gomez A, Licon K, Klepper K, Pekin D, Beckett AN, Sanchez KS, Thomas A, Kuo CC, Du D, Roguev A, ... ... Qi L, et al. Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions. Nature Methods. PMID 28319113 DOI: 10.1038/Nmeth.4225  0.357
2016 Wayne G, Graves A, Hassabis D, Saha S, Weber CA, Hyman AA, Juelicher F, Stroud DA, Ryan MT, Potvin-Trottier L, Paulsson J, Geiler-Samerotte KA, Siegal ML, Uhlen M, Edfors F, ... ... Qi LS, et al. Principles of Systems Biology, No. 11 Cell Systems. 3: 406-410. PMID 27883884 DOI: 10.1016/J.Cels.2016.11.010  0.332
2016 Gao Y, Xiong X, Wong S, Charles EJ, Lim WA, Qi LS. Complex transcriptional modulation with orthogonal and inducible dCas9 regulators. Nature Methods. PMID 27776111 DOI: 10.1038/Nmeth.4042  0.398
2016 Wang F, Qi LS. Applications of CRISPR Genome Engineering in Cell Biology. Trends in Cell Biology. PMID 27599850 DOI: 10.1016/J.Tcb.2016.08.004  0.396
2016 Peters JM, Colavin A, Shi H, Czarny TL, Larson MH, Wong S, Hawkins JS, Lu CH, Koo BM, Marta E, Shiver AL, Whitehead EH, Weissman JS, Brown ED, Qi LS, et al. A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria. Cell. PMID 27238023 DOI: 10.1016/J.Cell.2016.05.003  0.352
2016 Xiong X, Chen M, Lim WA, Zhao D, Qi LS. Genome Engineering and Disease Research. Annual Review of Genomics and Human Genetics. PMID 27216776 DOI: 10.1146/Annurev-Genom-083115-022258  0.398
2016 Wang H, La Russa M, Qi LS. CRISPR/Cas9 in Genome Editing and Beyond. Annual Review of Biochemistry. PMID 27145843 DOI: 10.1146/Annurev-Biochem-060815-014607  0.445
2016 Mandegar MA, Huebsch N, Frolov EB, Shin E, Truong A, Olvera MP, Chan AH, Miyaoka Y, Holmes K, Spencer CI, Judge LM, Gordon DE, Eskildsen TV, Villalta JE, Horlbeck MA, ... ... Qi LS, et al. CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs. Cell Stem Cell. PMID 26971820 DOI: 10.1016/J.Stem.2016.01.022  0.363
2016 Du D, Qi LS. An Introduction to CRISPR Technology for Genome Activation and Repression in Mammalian Cells. Cold Spring Harbor Protocols. 2016: pdb.top086835. PMID 26729914 DOI: 10.1101/Pdb.Top086835  0.442
2016 Du D, Qi LS. CRISPR Technology for Genome Activation and Repression in Mammalian Cells. Cold Spring Harbor Protocols. 2016: pdb.prot090175. PMID 26729910 DOI: 10.1101/Pdb.Prot090175  0.488
2016 Dingal PCDP, Kipniss N, Gao Y, Qi LS. Abstract B075: Conversion of extracellular signals to programmable genome manipulation via CRISPRouter Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-B075  0.425
2015 Dominguez AA, Lim WA, Qi LS. Beyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogation. Nature Reviews. Molecular Cell Biology. PMID 26670017 DOI: 10.1038/Nrm.2015.2  0.461
2015 Sokolik C, Liu Y, Bauer D, McPherson J, Broeker M, Heimberg G, Qi LS, Sivak DA, Thomson M. Transcription factor competition allows embryonic stem cells to distinguish authentic signals from noise. Cell Systems. 1: 117-129. PMID 26405695 DOI: 10.1016/J.Cels.2015.08.001  0.302
2015 La Russa MF, Qi LS. The New State of the Art: Cas9 for Gene Activation and Repression. Molecular and Cellular Biology. 35: 3800-9. PMID 26370509 DOI: 10.1128/Mcb.00512-15  0.382
2015 Peters JM, Silvis MR, Zhao D, Hawkins JS, Gross CA, Qi LS. Bacterial CRISPR: accomplishments and prospects. Current Opinion in Microbiology. 27: 121-126. PMID 26363124 DOI: 10.1016/J.Mib.2015.08.007  0.365
2015 Liu H, Wei Z, Dominguez A, Li Y, Wang X, Qi LS. CRISPR-ERA: a comprehensive design tool for CRISPR-mediated gene editing, repression and activation. Bioinformatics (Oxford, England). PMID 26209430 DOI: 10.1093/Bioinformatics/Btv423  0.445
2015 Hawkins JS, Wong S, Peters JM, Almeida R, Qi LS. Targeted Transcriptional Repression in Bacteria Using CRISPR Interference (CRISPRi). Methods in Molecular Biology (Clifton, N.J.). 1311: 349-62. PMID 25981485 DOI: 10.1007/978-1-4939-2687-9_23  0.447
2015 Yu C, Liu Y, Ma T, Liu K, Xu S, Zhang Y, Liu H, La Russa M, Xie M, Ding S, Qi LS. Small molecules enhance CRISPR genome editing in pluripotent stem cells. Cell Stem Cell. 16: 142-7. PMID 25658371 DOI: 10.1016/J.Stem.2015.01.003  0.38
2015 Zalatan JG, Lee ME, Almeida R, Gilbert LA, Whitehead EH, La Russa M, Tsai JC, Weissman JS, Dueber JE, Qi LS, Lim WA. Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds. Cell. 160: 339-50. PMID 25533786 DOI: 10.1016/J.Cell.2014.11.052  0.459
2014 Ji W, Lee D, Wong E, Dadlani P, Dinh D, Huang V, Kearns K, Teng S, Chen S, Haliburton J, Heimberg G, Heineike B, Ramasubramanian A, Stevens T, Helmke KJ, ... ... Qi LS, et al. Specific gene repression by CRISPRi system transferred through bacterial conjugation. Acs Synthetic Biology. 3: 929-31. PMID 25409531 DOI: 10.1021/Sb500036Q  0.353
2014 Tanenbaum ME, Gilbert LA, Qi LS, Weissman JS, Vale RD. A protein-tagging system for signal amplification in gene expression and fluorescence imaging. Cell. 159: 635-46. PMID 25307933 DOI: 10.1016/J.Cell.2014.09.039  0.351
2014 Gilbert LA, Horlbeck MA, Adamson B, Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman JS. Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation. Cell. 159: 647-61. PMID 25307932 DOI: 10.1016/J.Cell.2014.09.029  0.414
2014 Qi LS, Arkin AP. A versatile framework for microbial engineering using synthetic non-coding RNAs. Nature Reviews. Microbiology. 12: 341-54. PMID 24736794 DOI: 10.1038/Nrmicro3244  0.597
2013 Chen B, Gilbert LA, Cimini BA, Schnitzbauer J, Zhang W, Li GW, Park J, Blackburn EH, Weissman JS, Qi LS, Huang B. Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system. Cell. 155: 1479-91. PMID 24360272 DOI: 10.1016/J.Cell.2013.12.001  0.362
2013 Larson MH, Gilbert LA, Wang X, Lim WA, Weissman JS, Qi LS. CRISPR interference (CRISPRi) for sequence-specific control of gene expression. Nature Protocols. 8: 2180-96. PMID 24136345 DOI: 10.1038/Nprot.2013.132  0.505
2013 Gilbert LA, Larson MH, Morsut L, Liu Z, Brar GA, Torres SE, Stern-Ginossar N, Brandman O, Whitehead EH, Doudna JA, Lim WA, Weissman JS, Qi LS. CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes. Cell. 154: 442-51. PMID 23849981 DOI: 10.1016/J.Cell.2013.06.044  0.481
2013 Qi LS, Larson MH, Gilbert LA, Doudna JA, Weissman JS, Arkin AP, Lim WA. Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression. Cell. 152: 1173-83. PMID 23452860 DOI: 10.1016/J.Cell.2013.02.022  0.614
2012 Liu CC, Qi L, Lucks JB, Segall-Shapiro TH, Wang D, Mutalik VK, Arkin AP. An adaptor from translational to transcriptional control enables predictable assembly of complex regulation. Nature Methods. 9: 1088-94. PMID 23023598 DOI: 10.1038/Nmeth.2184  0.728
2012 Qi L, Haurwitz RE, Shao W, Doudna JA, Arkin AP. RNA processing enables predictable programming of gene expression. Nature Biotechnology. 30: 1002-6. PMID 22983090 DOI: 10.1038/Nbt.2355  0.603
2012 Mutalik VK, Qi L, Guimaraes JC, Lucks JB, Arkin AP. Rationally designed families of orthogonal RNA regulators of translation. Nature Chemical Biology. 8: 447-54. PMID 22446835 DOI: 10.1038/Nchembio.919  0.725
2012 Qi L, Lucks JB, Liu CC, Mutalik VK, Arkin AP. Engineering naturally occurring trans-acting non-coding RNAs to sense molecular signals. Nucleic Acids Research. 40: 5775-86. PMID 22383579 DOI: 10.1093/Nar/Gks168  0.738
2011 Lucks JB, Qi L, Mutalik VK, Wang D, Arkin AP. Versatile RNA-sensing transcriptional regulators for engineering genetic networks. Proceedings of the National Academy of Sciences of the United States of America. 108: 8617-22. PMID 21555549 DOI: 10.1073/Pnas.1015741108  0.729
2011 Liu CC, Qi L, Yanofsky C, Arkin AP. Regulation of transcription by unnatural amino acids. Nature Biotechnology. 29: 164-8. PMID 21240267 DOI: 10.1038/Nbt.1741  0.579
2008 Lucks JB, Qi L, Whitaker WR, Arkin AP. Toward scalable parts families for predictable design of biological circuits. Current Opinion in Microbiology. 11: 567-73. PMID 18983935 DOI: 10.1016/J.Mib.2008.10.002  0.707
Show low-probability matches.