Haining Zhu, Ph.D. - Publications

Affiliations: 
2000 University of California, Los Angeles, Los Angeles, CA 
Area:
Copper-Zinc Superoxide Dismutase and ALS, Redox Balance, Oxidative Stress, and Metal Ion Metabolism in Eukaryotic Cells

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Gal J, Kuang L, Barnett KR, Zhu BZ, Shissler SC, Korotkov KV, Hayward LJ, Kasarskis EJ, Zhu H. ALS mutant SOD1 interacts with G3BP1 and affects stress granule dynamics. Acta Neuropathologica. PMID 27481264 DOI: 10.1007/s00401-016-1601-x  0.76
2016 Kamelgarn M, Chen J, Kuang L, Arenas A, Zhai J, Zhu H, Gal J. Proteomic analysis of FUS interacting proteins provides insights into FUS function and its role in ALS. Biochimica Et Biophysica Acta. PMID 27460707 DOI: 10.1016/j.bbadis.2016.07.015  0.76
2016 Liu M, Verma N, Peng X, Srodulski S, Morris A, Chow M, Hersh LB, Chen J, Zhu H, Netea MG, Margulies KB, Despa S, Despa F. Hyperamylinemia Increases IL-1β Synthesis in the Heart via Peroxidative Sarcolemmal Injury. Diabetes. PMID 27335231 DOI: 10.2337/db16-0044  0.76
2015 Yang L, Zhang J, Kamelgarn M, Niu C, Gal J, Gong W, Zhu H. Subcellular localization and RNAs determine FUS architecture in different cellular compartments. Human Molecular Genetics. PMID 26123490 DOI: 10.1093/hmg/ddv239  0.76
2014 Yang L, Gal J, Chen J, Zhu H. Self-assembled FUS binds active chromatin and regulates gene transcription. Proceedings of the National Academy of Sciences of the United States of America. 111: 17809-14. PMID 25453086 DOI: 10.1073/pnas.1414004111  0.76
2014 Elshahawi SI, Ramelot TA, Seetharaman J, Chen J, Singh S, Yang Y, Pederson K, Kharel MK, Xiao R, Lew S, Yennamalli RM, Miller MD, Wang F, Tong L, Montelione GT, ... ... Zhu H, et al. Structure-guided functional characterization of enediyne self-sacrifice resistance proteins, CalU16 and CalU19. Acs Chemical Biology. 9: 2347-58. PMID 25079510 DOI: 10.1021/cb500327m  0.76
2014 Shi J, Wang Y, Zeng L, Wu Y, Deng J, Zhang Q, Lin Y, Li J, Kang T, Tao M, Rusinova E, Zhang G, Wang C, Zhu H, Yao J, et al. Disrupting the interaction of BRD4 with diacetylated Twist suppresses tumorigenesis in basal-like breast cancer. Cancer Cell. 25: 210-25. PMID 24525235 DOI: 10.1016/j.ccr.2014.01.028  0.76
2014 Dhar SK, Zhang J, Gal J, Xu Y, Miao L, Lynn BC, Zhu H, Kasarskis EJ, St Clair DK. FUsed in sarcoma is a novel regulator of manganese superoxide dismutase gene transcription. Antioxidants & Redox Signaling. 20: 1550-66. PMID 23834335 DOI: 10.1089/ars.2012.4984  0.76
2013 Wagner JM, Evans TJ, Chen J, Zhu H, Houben EN, Bitter W, Korotkov KV. Understanding specificity of the mycosin proteases in ESX/type VII secretion by structural and functional analysis. Journal of Structural Biology. 184: 115-28. PMID 24113528 DOI: 10.1016/j.jsb.2013.09.022  0.76
2013 Pandya RS, Zhu H, Li W, Bowser R, Friedlander RM, Wang X. Therapeutic neuroprotective agents for amyotrophic lateral sclerosis. Cellular and Molecular Life Sciences : Cmls. 70: 4729-45. PMID 23864030 DOI: 10.1007/s00018-013-1415-0  0.76
2013 Jutras BL, Chenail AM, Carroll DW, Miller MC, Zhu H, Bowman A, Stevenson B. Bpur, the Lyme disease spirochete's PUR domain protein: identification as a transcriptional modulator and characterization of nucleic acid interactions. The Journal of Biological Chemistry. 288: 26220-34. PMID 23846702 DOI: 10.1074/jbc.M113.491357  0.76
2013 Gal J, Chen J, Barnett KR, Yang L, Brumley E, Zhu H. HDAC6 regulates mutant SOD1 aggregation through two SMIR motifs and tubulin acetylation. The Journal of Biological Chemistry. 288: 15035-45. PMID 23580651 DOI: 10.1074/jbc.M112.431957  0.76
2013 Li X, Zhou Q, Sunkara M, Kutys ML, Wu Z, Rychahou P, Morris AJ, Zhu H, Evers BM, Huang C. Ubiquitylation of phosphatidylinositol 4-phosphate 5-kinase type I γ by HECTD1 regulates focal adhesion dynamics and cell migration. Journal of Cell Science. 126: 2617-28. PMID 23572508 DOI: 10.1242/jcs.117044  0.76
2013 Convertini P, Zhang J, de la Grange P, Hayward LJ, Zhu H, Stamm S. Genome wide array analysis indicates that an amyotrophic lateral sclerosis mutation of FUS causes an early increase of CAMK2N2 in vitro. Biochimica Et Biophysica Acta. 1832: 1129-35. PMID 23545117 DOI: 10.1016/j.bbadis.2013.03.015  0.76
2013 Liu X, Niu C, Ren J, Zhang J, Xie X, Zhu H, Feng W, Gong W. The RRM domain of human fused in sarcoma protein reveals a non-canonical nucleic acid binding site. Biochimica Et Biophysica Acta. 1832: 375-85. PMID 23200923 DOI: 10.1016/j.bbadis.2012.11.012  0.76
2012 Niu C, Zhang J, Gao F, Yang L, Jia M, Zhu H, Gong W. FUS-NLS/Transportin 1 complex structure provides insights into the nuclear targeting mechanism of FUS and the implications in ALS. Plos One. 7: e47056. PMID 23056579 DOI: 10.1371/journal.pone.0047056  0.76
2012 Wang G, Pahari P, Kharel MK, Chen J, Zhu H, Van Lanen SG, Rohr J. Cooperation of two bifunctional enzymes in the biosynthesis and attachment of deoxysugars of the antitumor antibiotic mithramycin. Angewandte Chemie (International Ed. in English). 51: 10638-42. PMID 22997042 DOI: 10.1002/anie.201205414  0.76
2012 Zhao J, Chen J, Zhu H, Xiong YL. Mass spectrometric evidence of malonaldehyde and 4-hydroxynonenal adductions to radical-scavenging soy peptides. Journal of Agricultural and Food Chemistry. 60: 9727-36. PMID 22946674 DOI: 10.1021/jf3026277  0.76
2012 Kuo KL, Zhu H, McNamara PJ, Leggas M. Localization and functional characterization of the rat Oatp4c1 transporter in an in vitro cell system and rat tissues. Plos One. 7: e39641. PMID 22768102 DOI: 10.1371/journal.pone.0039641  0.76
2012 Lu W, Chai Q, Zhong M, Yu L, Fang J, Wang T, Li H, Zhu H, Wei Y. Assembling of AcrB trimer in cell membrane. Journal of Molecular Biology. 423: 123-34. PMID 22766312 DOI: 10.1016/j.jmb.2012.06.036  0.76
2012 Martin SK, Vaughan TB, Atkinson T, Zhu H, Kyprianou N. Emerging biomarkers of prostate cancer (Review). Oncology Reports. 28: 409-17. PMID 22641253 DOI: 10.3892/or.2012.1832  0.76
2012 Xia R, Liu Y, Yang L, Gal J, Zhu H, Jia J. Motor neuron apoptosis and neuromuscular junction perturbation are prominent features in a Drosophila model of Fus-mediated ALS. Molecular Neurodegeneration. 7: 10. PMID 22443542 DOI: 10.1186/1750-1326-7-10  0.76
2012 Tang X, Seyb KI, Huang M, Schuman ER, Shi P, Zhu H, Glicksman MA. A high-throughput screening method for small-molecule inhibitors of the aberrant mutant SOD1 and dynein complex interaction. Journal of Biomolecular Screening. 17: 314-26. PMID 22140121 DOI: 10.1177/1087057111429595  0.76
2012 Zhu H, Zhao J, Zhu B, Collazo J, Gal J, Shi P, Liu L, Ström AL, Lu X, McCann RO, Toborek M, Kyprianou N. EMMPRIN regulates cytoskeleton reorganization and cell adhesion in prostate cancer. The Prostate. 72: 72-81. PMID 21563192 DOI: 10.1002/pros.21408  0.76
2011 Tang X, Tang X, Gal J, Kyprianou N, Zhu H, Tang G. Detection of microRNAs in prostate cancer cells by microRNA array. Methods in Molecular Biology (Clifton, N.J.). 732: 69-88. PMID 21431706 DOI: 10.1007/978-1-61779-083-6_6  0.76
2011 Gal J, Zhang J, Kwinter DM, Zhai J, Jia H, Jia J, Zhu H. Nuclear localization sequence of FUS and induction of stress granules by ALS mutants. Neurobiology of Aging. 32: 2323.e27-40. PMID 20674093 DOI: 10.1016/j.neurobiolaging.2010.06.010  0.76
2010 Shi P, Ström AL, Gal J, Zhu H. Effects of ALS-related SOD1 mutants on dynein- and KIF5-mediated retrograde and anterograde axonal transport. Biochimica Et Biophysica Acta. 1802: 707-16. PMID 20510358 DOI: 10.1016/j.bbadis.2010.05.008  0.76
2010 Shi P, Wei Y, Zhang J, Gal J, Zhu H. Mitochondrial dysfunction is a converging point of multiple pathological pathways in amyotrophic lateral sclerosis. Journal of Alzheimer's Disease : Jad. 20: S311-24. PMID 20463400 DOI: 10.3233/JAD-2010-100366  0.76
2010 Ma Y, Xiong YL, Zhai J, Zhu H, Dziubla T. Fractionation and evaluation of radical-scavenging peptides from in vitro digests of buckwheat protein. Food Chemistry. 118: 582-588. PMID 20352082 DOI: 10.1016/j.foodchem.2009.05.024  0.76
2010 Zhu B, Zhai J, Zhu H, Kyprianou N. Prohibitin regulates TGF-beta induced apoptosis as a downstream effector of Smad-dependent and -independent signaling. The Prostate. 70: 17-26. PMID 19725029 DOI: 10.1002/pros.21033  0.76
2010 Shi P, Gal J, Kwinter DM, Liu X, Zhu H. Mitochondrial dysfunction in amyotrophic lateral sclerosis. Biochimica Et Biophysica Acta. 1802: 45-51. PMID 19715760 DOI: 10.1016/j.bbadis.2009.08.012  0.76
2009 Gal J, Ström AL, Kwinter DM, Kilty R, Zhang J, Shi P, Fu W, Wooten MW, Zhu H. Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism. Journal of Neurochemistry. 111: 1062-73. PMID 19765191 DOI: 10.1111/j.1471-4159.2009.06388.x  0.76
2009 Zhai J, Ström AL, Kilty R, Venkatakrishnan P, White J, Everson WV, Smart EJ, Zhu H. Proteomic characterization of lipid raft proteins in amyotrophic lateral sclerosis mouse spinal cord. The Febs Journal. 276: 3308-23. PMID 19438725 DOI: 10.1111/j.1742-4658.2009.07057.x  0.76
2009 Zhai J, Liu X, Huang Z, Zhu H. RABA (reductive alkylation by acetone): a novel stable isotope labeling approach for quantitative proteomics. Journal of the American Society For Mass Spectrometry. 20: 1366-77. PMID 19419886 DOI: 10.1016/j.jasms.2009.03.027  0.76
2009 Liu R, Ström AL, Zhai J, Gal J, Bao S, Gong W, Zhu H. Enzymatically inactive adenylate kinase 4 interacts with mitochondrial ADP/ATP translocase. The International Journal of Biochemistry & Cell Biology. 41: 1371-80. PMID 19130895 DOI: 10.1016/j.biocel.2008.12.002  0.76
2008 Ström AL, Shi P, Zhang F, Gal J, Kilty R, Hayward LJ, Zhu H. Interaction of amyotrophic lateral sclerosis (ALS)-related mutant copper-zinc superoxide dismutase with the dynein-dynactin complex contributes to inclusion formation. The Journal of Biological Chemistry. 283: 22795-805. PMID 18515363 DOI: 10.1074/jbc.M800276200  0.76
2008 Ström AL, Gal J, Shi P, Kasarskis EJ, Hayward LJ, Zhu H. Retrograde axonal transport and motor neuron disease. Journal of Neurochemistry. 106: 495-505. PMID 18384644 DOI: 10.1111/j.1471-4159.2008.05393.x  0.76
2008 Ramesh Babu J, Lamar Seibenhener M, Peng J, Strom AL, Kemppainen R, Cox N, Zhu H, Wooten MC, Diaz-Meco MT, Moscat J, Wooten MW. Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration. Journal of Neurochemistry. 106: 107-20. PMID 18346206 DOI: 10.1111/j.1471-4159.2008.05340.x  0.76
2008 White J, Guerin T, Swanson H, Post S, Zhu H, Gong M, Liu J, Everson WV, Li XA, Graf GA, Ballard HO, Ross SA, Smart EJ. Diabetic HDL-associated myristic acid inhibits acetylcholine-induced nitric oxide generation by preventing the association of endothelial nitric oxide synthase with calmodulin. American Journal of Physiology. Cell Physiology. 294: C295-305. PMID 17977947 DOI: 10.1152/ajpcell.00042.2007  0.76
2007 Hou X, Liu R, Ross S, Smart EJ, Zhu H, Gong W. Crystallographic studies of human MitoNEET. The Journal of Biological Chemistry. 282: 33242-6. PMID 17905743 DOI: 10.1074/jbc.C700172200  0.76
2007 Tang X, Gal J, Zhuang X, Wang W, Zhu H, Tang G. A simple array platform for microRNA analysis and its application in mouse tissues. Rna (New York, N.Y.). 13: 1803-22. PMID 17675362 DOI: 10.1261/rna.498607  0.76
2007 Zhang F, Ström AL, Fukada K, Lee S, Hayward LJ, Zhu H. Interaction between familial amyotrophic lateral sclerosis (ALS)-linked SOD1 mutants and the dynein complex. The Journal of Biological Chemistry. 282: 16691-9. PMID 17403682 DOI: 10.1074/jbc.M609743200  0.76
2007 Potter SZ, Zhu H, Shaw BF, Rodriguez JA, Doucette PA, Sohn SH, Durazo A, Faull KF, Gralla EB, Nersissian AM, Valentine JS. Binding of a single zinc ion to one subunit of copper-zinc superoxide dismutase apoprotein substantially influences the structure and stability of the entire homodimeric protein. Journal of the American Chemical Society. 129: 4575-83. PMID 17381088 DOI: 10.1021/ja066690+  0.76
2007 Gal J, Ström AL, Kilty R, Zhang F, Zhu H. p62 accumulates and enhances aggregate formation in model systems of familial amyotrophic lateral sclerosis. The Journal of Biological Chemistry. 282: 11068-77. PMID 17296612 DOI: 10.1074/jbc.M608787200  0.76
2006 Zhu B, Fukada K, Zhu H, Kyprianou N. Prohibitin and cofilin are intracellular effectors of transforming growth factor beta signaling in human prostate cancer cells. Cancer Research. 66: 8640-7. PMID 16951178 DOI: 10.1158/0008-5472.CAN-06-1443  0.76
2006 Zhang F, Zhu H. Intracellular conformational alterations of mutant SOD1 and the implications for fALS-associated SOD1 mutant induced motor neuron cell death. Biochimica Et Biophysica Acta. 1760: 404-14. PMID 16431026 DOI: 10.1016/j.bbagen.2005.11.024  0.76
2005 Lu X, Zhu H. Tube-gel digestion: a novel proteomic approach for high throughput analysis of membrane proteins. Molecular & Cellular Proteomics : McP. 4: 1948-58. PMID 16150870 DOI: 10.1074/mcp.M500138-MCP200  0.76
2004 Fukada K, Zhang F, Vien A, Cashman NR, Zhu H. Mitochondrial proteomic analysis of a cell line model of familial amyotrophic lateral sclerosis. Molecular & Cellular Proteomics : McP. 3: 1211-23. PMID 15501831 DOI: 10.1074/mcp.M400094-MCP200  0.76
2002 Zhu H, Pan S, Gu S, Bradbury EM, Chen X. Amino acid residue specific stable isotope labeling for quantitative proteomics. Rapid Communications in Mass Spectrometry : Rcm. 16: 2115-23. PMID 12415544 DOI: 10.1002/rcm.831  0.76
2002 Zhu H, Hunter TC, Pan S, Yau PM, Bradbury EM, Chen X. Residue-specific mass signatures for the efficient detection of protein modifications by mass spectrometry. Analytical Chemistry. 74: 1687-94. PMID 12033261 DOI: 10.1021/ac010853p  0.76
2000 Zhu H, Shipp E, Sanchez RJ, Liba A, Stine JE, Hart PJ, Gralla EB, Nersissian AM, Valentine JS. Cobalt(2+) binding to human and tomato copper chaperone for superoxide dismutase: implications for the metal ion transfer mechanism. Biochemistry. 39: 5413-21. PMID 10820013 DOI: 10.1021/bi992727+  0.76
1998 Lyons TJ, Nersissian A, Goto JJ, Zhu H, Gralla EB, Valentine JS. Metal ion reconstitution studies of yeast copper-zinc superoxide dismutase: The 'phantom' subunit and the possible role of Lys7p Journal of Biological Inorganic Chemistry. 3: 650-662. DOI: 10.1007/s007750050279  0.76
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