Suwen Zhao, Ph.D. - Publications

2009 Columbia University, New York, NY 
Computational Chemistry

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Liu K, Wu L, Yuan S, Wu M, Xu Y, Sun Q, Li S, Zhao S, Hua T, Liu ZJ. Structural basis of CXC chemokine receptor 2 activation and signalling. Nature. PMID 32610344 DOI: 10.1038/S41586-020-2492-5  0.354
2020 Yu J, Gimenez LE, Hernandez CC, Wu Y, Wein AH, Han GW, McClary K, Mittal SR, Burdsall K, Stauch B, Wu L, Stevens SN, Peisley A, Williams SY, Chen V, ... ... Zhao S, et al. Determination of the melanocortin-4 receptor structure identifies Ca as a cofactor for ligand binding. Science (New York, N.Y.). 368: 428-433. PMID 32327598 DOI: 10.1126/Science.Aaz8995  0.362
2020 Zhang B, Tastan ÖY, Zhou X, Guo CJ, Liu X, Thind A, Hu HH, Zhao S, Liu JL. The proline synthesis enzyme P5CS forms cytoophidia in Drosophila. Journal of Genetics and Genomics = Yi Chuan Xue Bao. PMID 32317150 DOI: 10.1016/J.Jgg.2020.02.005  0.305
2020 Wang J, Wu M, Wu L, Xu Y, Li F, Wu Y, Popov P, Wang L, Bai F, Zhao S, Liu ZJ, Hua T. The structural study of mutation-induced inactivation of human muscarinic receptor M4. Iucrj. 7: 294-305. PMID 32148857 DOI: 10.1107/S2052252520000597  0.315
2020 Zhang B, Zhao S, Yang D, Wu Y, Xin Y, Cao H, Huang XP, Cai X, Sun W, Ye N, Xu Y, Peng Y, Zhao S, Liu ZJ, Zhong G, et al. A Novel G Protein-Biased and Subtype-Selective Agonist for a G Protein-Coupled Receptor Discovered from Screening Herbal Extracts. Acs Central Science. 6: 213-225. PMID 32123739 DOI: 10.1021/Acscentsci.9B01125  0.336
2020 Lin X, Li M, Wang N, Wu Y, Luo Z, Guo S, Han GW, Li S, Yue Y, Wei X, Xie X, Chen Y, Zhao S, Wu J, Lei M, et al. Structural basis of ligand recognition and self-activation of orphan GPR52. Nature. PMID 32076264 DOI: 10.1038/S41586-020-2019-0  0.351
2020 Xia L, Ma Z, Tong J, Tang Y, Li S, Qin S, Lou R, Zhao S, Lei X, Shui W. Evaluation of chemical cross-linkers for in-depth structural analysis of G protein-coupled receptors through cross-linking mass spectrometry. Analytica Chimica Acta. 1102: 53-62. PMID 32043996 DOI: 10.1016/J.Aca.2019.12.036  0.354
2020 Hua T, Li X, Wu L, Iliopoulos-Tsoutsouvas C, Wang Y, Wu M, Shen L, Johnston CA, Nikas SP, Song F, Song X, Yuan S, Sun Q, Wu Y, Jiang S, ... ... Zhao S, et al. Activation and Signaling Mechanism Revealed by Cannabinoid Receptor-G Complex Structures. Cell. PMID 32004463 DOI: 10.1016/J.Cell.2020.01.008  0.354
2020 Lu L, Guo Y, Wang T, Liang L, Zhao S, Wang F, Liu L. Inactivity of YGL082W in vitro due to impairment of conformational change in the catalytic center loop Science China-Chemistry. 63: 237-243. DOI: 10.1007/S11426-019-9623-0  0.34
2019 Zhou Q, Yang D, Wu M, Guo Y, Guo W, Zhong L, Cai X, Dai A, Jang W, Shakhnovich EI, Liu ZJ, Stevens RC, Lambert NA, Babu MM, Wang MW, ... Zhao S, et al. Common activation mechanism of class A GPCRs. Elife. 8. PMID 31855179 DOI: 10.7554/Elife.50279  0.373
2019 Chen X, Xu Y, Qu L, Wu L, Han GW, Guo Y, Wu Y, Zhou Q, Sun Q, Chu C, Yang J, Yang L, Wang Q, Yuan S, Wang L, ... ... Zhao S, et al. Molecular Mechanism for Ligand Recognition and Subtype Selectivity of α Adrenergic Receptor. Cell Reports. 29: 2936-2943.e4. PMID 31801061 DOI: 10.1016/J.Celrep.2019.10.112  0.33
2019 Qu L, Zhou Q, Xu Y, Guo Y, Chen X, Yao D, Han GW, Liu ZJ, Stevens RC, Zhong G, Wu D, Zhao S. Structural Basis of the Diversity of Adrenergic Receptors. Cell Reports. 29: 2929-2935.e4. PMID 31801060 DOI: 10.1016/J.Celrep.2019.10.088  0.361
2019 Wu Y, Tong J, Ding K, Zhou Q, Zhao S. GPCR Allosteric Modulator Discovery. Advances in Experimental Medicine and Biology. 1163: 225-251. PMID 31707706 DOI: 10.1007/978-981-13-8719-7_10  0.333
2019 Zhou F, Ding K, Zhou Y, Liu Y, Liu X, Zhao F, Wu Y, Zhang X, Tan Q, Stevens RC, Xu F, Tan W, Xiao Y, Zhao S, Tao H. Co-Localization Strategy Unveils an Underside Binding Site in the Transmembrane Domain of Smoothened Receptor. Journal of Medicinal Chemistry. PMID 31408335 DOI: 10.1021/Acs.Jmedchem.9B00283  0.337
2019 Xue D, Xu T, Wang H, Wu M, Yuan Y, Wang W, Tan Q, Zhao F, Zhou F, Hu T, Jiang Z, Liu ZJ, Zhao S, Liu D, Wüthrich K, et al. Disulfide-Containing Detergents (DCDs) for the Structural Biology of Membrane Proteins. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31368214 DOI: 10.1002/Chem.201903190  0.348
2019 Zhao S, Wu B, Stevens RC. Advancing Chemokine GPCR Structure Based Drug Discovery. Structure (London, England : 1993). 27: 405-408. PMID 30840872 DOI: 10.1016/J.Str.2019.02.004  0.325
2018 Zhang S, Ding K, Shen QJ, Zhao S, Liu JL. Filamentation of asparagine synthetase in Saccharomyces cerevisiae. Plos Genetics. 14: e1007737. PMID 30365499 DOI: 10.1371/Journal.Pgen.1007737  0.319
2018 Yang S, Wu Y, Xu TH, de Waal PW, He Y, Pu M, Chen Y, DeBruine ZJ, Zhang B, Zaidi SA, Popov P, Guo Y, Han GW, Lu Y, Suino-Powell K, ... ... Zhao S, et al. Crystal structure of the Frizzled 4 receptor in a ligand-free state. Nature. PMID 30135577 DOI: 10.1038/S41586-018-0447-X  0.385
2018 Liu X, Gao ZG, Wu Y, Stevens RC, Jacobson KA, Zhao S. Salvianolic acids from antithrombotic Traditional Chinese Medicine Danshen are antagonists of human P2Y and P2Y receptors. Scientific Reports. 8: 8084. PMID 29795391 DOI: 10.1038/S41598-018-26577-0  0.3
2018 Qin S, Meng M, Yang D, Bai W, Lu Y, Peng Y, Song G, Wu Y, Zhou Q, Zhao S, Huang X, McCorvy JD, Cai X, Dai A, Roth BL, et al. High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening. Chemical Science. 9: 3192-3199. PMID 29732102 DOI: 10.1039/C7Sc04698G  0.325
2018 Peng Y, Zhao S, Wu Y, Cao H, Xu Y, Liu X, Shui W, Cheng J, Zhao S, Shen L, Ma J, Quinn RJ, Stevens RC, Zhong G, Liu ZJ. Identification of natural products as novel ligands for the human 5-HTreceptor. Biophysics Reports. 4: 50-61. PMID 29577069 DOI: 10.1007/S41048-018-0047-1  0.358
2018 Peng Y, McCorvy JD, Harpsøe K, Lansu K, Yuan S, Popov P, Qu L, Pu M, Che T, Nikolajsen LF, Huang XP, Wu Y, Shen L, Bjørn-Yoshimoto WE, Ding K, ... ... Zhao S, et al. 5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology. Cell. PMID 29398112 DOI: 10.1016/J.Cell.2018.01.001  0.334
2018 Calhoun S, Korczynska M, Wichelecki DJ, San Francisco B, Zhao S, Rodionov DA, Vetting MW, Al-Obaidi NF, Lin H, O'Meara MJ, Scott DA, Morris JH, Russel D, Almo SC, Osterman AL, et al. Prediction of enzymatic pathways by integrative pathway mapping. Elife. 7. PMID 29377793 DOI: 10.7554/Elife.31097  0.328
2017 Ye L, Ding K, Zhao F, Liu X, Wu Y, Liu Y, Xue D, Zhou F, Zhang X, Stevens RC, Xu F, Zhao S, Tao H. A structurally guided dissection-then-evolution strategy for ligand optimization of smoothened receptor. Medchemcomm. 8: 1332-1336. PMID 30108845 DOI: 10.1039/C7Md00104E  0.342
2017 Li Z, Tang Y, Wu Y, Zhao S, Bao J, Luo Y, Li D. Structural insights into the committed step of bacterial phospholipid biosynthesis. Nature Communications. 8: 1691. PMID 29167463 DOI: 10.1038/S41467-017-01821-9  0.347
2017 Hua T, Vemuri K, Nikas SP, Laprairie RB, Wu Y, Qu L, Pu M, Korde A, Jiang S, Ho JH, Han GW, Ding K, Li X, Liu H, Hanson MA, ... Zhao S, et al. Crystal structures of agonist-bound human cannabinoid receptor CB1. Nature. PMID 28678776 DOI: 10.1038/Nature23272  0.385
2017 Yang L, Tae HS, Fan Z, Shao X, Xu S, Zhao S, Adams DJ, Wang C. A Novel Lid-Covering Peptide Inhibitor of Nicotinic Acetylcholine Receptors Derived from αD-Conotoxin GeXXA. Marine Drugs. 15. PMID 28587231 DOI: 10.3390/Md15060164  0.317
2017 Ma Y, Yue Y, Ma Y, Zhang Q, Zhou Q, Song Y, Shen Y, Li X, Ma X, Li C, Hanson MA, Han GW, Sickmier EA, Swaminath G, Zhao S, et al. Structural Basis for Apelin Control of the Human Apelin Receptor. Structure (London, England : 1993). PMID 28528775 DOI: 10.1016/J.Str.2017.04.008  0.344
2017 Song G, Yang D, Wang Y, de Graaf C, Zhou Q, Jiang S, Liu K, Cai X, Dai A, Lin G, Liu D, Wu F, Wu Y, Zhao S, Ye L, et al. Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators. Nature. PMID 28514449 DOI: 10.1038/Nature22378  0.347
2017 Zhang X, Zhao F, Wu Y, Yang J, Han GW, Zhao S, Ishchenko A, Ye L, Lin X, Ding K, Dharmarajan V, Griffin PR, Gati C, Nelson G, Hunter MS, et al. Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand. Nature Communications. 8: 15383. PMID 28513578 DOI: 10.1038/Ncomms15383  0.351
2016 Hua T, Vemuri K, Pu M, Qu L, Han GW, Wu Y, Zhao S, Shui W, Li S, Korde A, Laprairie RB, Stahl EL, Ho JH, Zvonok N, Zhou H, et al. Crystal Structure of the Human Cannabinoid Receptor CB1. Cell. 167: 750-762.e14. PMID 27768894 DOI: 10.1016/J.Cell.2016.10.004  0.352
2016 Lan C, Zhao S, Xu T, Ma J, Hayase S, Ma T. Investigation on structures, band gaps, and electronic structures of lead free La2NiMnO6 double perovskite materials for potential application of solar cell Journal of Alloys and Compounds. 655: 208-214. DOI: 10.1016/j.jallcom.2015.09.187  0.393
2015 Tang Z, Yu W, Zhang C, Zhao S, Yu Z, Xiao X, Tang R, Xuan Y, Yang W, Hao J, Xu T, Zhang Q, Huang W, Deng W, Guo W. CREB-binding protein regulates lung cancer growth by targeting MAPK and CPSF4 signaling pathway. Molecular Oncology. PMID 26628108 DOI: 10.1016/j.molonc.2015.10.015  0.523
2015 Zheng W, Yin T, Chen Q, Qin X, Huang X, Zhao S, Xu T, Chen L, Liu J. Co-delivery of Se Nanoparticles and Pooled SiRNAs for Overcoming Drug Resistance Mediated by P-glycoprotein and Class III β-tubulin in Drug-resistant Breast Cancers. Acta Biomaterialia. PMID 26612416 DOI: 10.1016/j.actbio.2015.11.041  0.382
2015 Vetting MW, Al-Obaidi N, Zhao S, San Francisco B, Kim J, Wichelecki DJ, Bouvier JT, Solbiati JO, Vu H, Zhang X, Rodionov DA, Love JD, Hillerich BS, Seidel RD, Quinn RJ, et al. Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes. Biochemistry. 54: 909-31. PMID 25540822 DOI: 10.1021/Bi501388Y  0.302
2014 Jacobson MP, Kalyanaraman C, Zhao S, Tian B. Leveraging structure for enzyme function prediction: methods, opportunities, and challenges. Trends in Biochemical Sciences. 39: 363-71. PMID 24998033 DOI: 10.1016/J.Tibs.2014.05.006  0.346
2013 Zhao S, Kumar R, Sakai A, Vetting MW, Wood BM, Brown S, Bonanno JB, Hillerich BS, Seidel RD, Babbitt PC, Almo SC, Sweedler JV, Gerlt JA, Cronan JE, Jacobson MP. Discovery of new enzymes and metabolic pathways by using structure and genome context. Nature. 502: 698-702. PMID 24056934 DOI: 10.1038/Nature12576  0.359
2013 Miller EB, Murrett CS, Zhu K, Zhao S, Goldfeld DA, Bylund JH, Friesner RA. Prediction of Long Loops with Embedded Secondary Structure using the Protein Local Optimization Program. Journal of Chemical Theory and Computation. 9: 1846-4864. PMID 23814507 DOI: 10.1021/Ct301083Q  0.706
2011 Zhao S, Zhu K, Li J, Friesner RA. Progress in super long loop prediction. Proteins. 79: 2920-35. PMID 21905115 DOI: 10.1002/Prot.23129  0.676
2011 Li J, Abel R, Zhu K, Cao Y, Zhao S, Friesner RA. The VSGB 2.0 model: a next generation energy model for high resolution protein structure modeling. Proteins. 79: 2794-812. PMID 21905107 DOI: 10.1002/Prot.23106  0.709
2008 Sellers BD, Zhu K, Zhao S, Friesner RA, Jacobson MP. Toward better refinement of comparative models: predicting loops in inexact environments. Proteins. 72: 959-71. PMID 18300241 DOI: 10.1002/Prot.21990  0.596
2007 Li X, Jacobson MP, Zhu K, Zhao S, Friesner RA. Assignment of polar states for protein amino acid residues using an interaction cluster decomposition algorithm and its application to high resolution protein structure modeling. Proteins. 66: 824-37. PMID 17154422 DOI: 10.1002/Prot.21125  0.536
2006 Zhu K, Pincus DL, Zhao S, Friesner RA. Long loop prediction using the protein local optimization program. Proteins. 65: 438-52. PMID 16927380 DOI: 10.1002/Prot.21040  0.709
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