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Dana Ferraris, Ph.D. - Publications

Affiliations: 
2000 Johns Hopkins University, Baltimore, MD 
Area:
Synthetic Organic Chemistry and Catalysis
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51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Rais R, Jancarik A, Tenora L, Nedelcovych M, Alt J, Englert J, Rojas C, Le A, Elgogary A, Tan J, Monincova L, Pate K, Adams RJ, Ferraris DV, Powell JD, et al. Discovery of 6-Diazo-5-oxo-L-norleucine (DON) prodrugs with enhanced CSF delivery in monkeys: a potential treatment for glioblastoma. Journal of Medicinal Chemistry. PMID 27560860 DOI: 10.1021/acs.jmedchem.6b01069  0.76
2016 Novakova Z, Wozniak K, Jancarik A, Rais R, Wu Y, Pavlicek J, Ferraris DV, Havlinova B, Ptacek J, Vavra J, Hin N, Rojas C, Majer P, Slusher BS, Tsukamoto T, et al. Unprecedented binding mode of hydroxamate-based inhibitors of glutamate carboxypeptidase II: structural characterization and biological activity. Journal of Medicinal Chemistry. PMID 27074627 DOI: 10.1021/acs.jmedchem.5b01806  0.76
2016 Hin N, Duvall B, Berry JF, Ferraris DV, Rais R, Alt J, Rojas C, Slusher BS, Tsukamoto T. d-Amino acid oxidase inhibitors based on the 5-hydroxy-1,2,4-triazin-6(1H)-one scaffold. Bioorganic & Medicinal Chemistry Letters. PMID 26965861 DOI: 10.1016/j.bmcl.2016.02.068  0.76
2016 Majer P, Jančarík A, Krečmerová M, Tichý T, Tenora L, Wozniak K, Wu Y, Pommier E, Ferraris DV, Rais R, Slusher BS. Discovery of orally available prodrugs of the Glutamate Carboxypeptidase II (GCP II) inhibitor 2-phosphonomethyl pentanedioic acid (2-PMPA). Journal of Medicinal Chemistry. PMID 26930119 DOI: 10.1021/acs.jmedchem.6b00062  0.76
2015 Rojas C, Alt J, Ator NA, Thomas AG, Wu Y, Hin N, Wozniak K, Ferraris D, Rais R, Tsukamoto T, Slusher BS. D-Amino Acid Oxidase Inhibition Increases D-Serine Plasma Levels in Mouse But not Monkey or Dog. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26471255 DOI: 10.1038/npp.2015.319  0.76
2015 Hin N, Duvall B, Ferraris D, Alt J, Thomas AG, Rais R, Rojas C, Wu Y, Wozniak KM, Slusher BS, Tsukamoto T. 6-Hydroxy-1,2,4-triazine-3,5(2H,4H)-dione Derivatives as Novel D-Amino Acid Oxidase Inhibitors. Journal of Medicinal Chemistry. PMID 26309148 DOI: 10.1021/acs.jmedchem.5b00482  0.76
2014 Hin N, Alt J, Zimmermann SC, Delahanty G, Ferraris DV, Rojas C, Li F, Liu Q, Dong X, Slusher BS, Tsukamoto T. Peptidomimetics of Arg-Phe-NH2 as small molecule agonists of Mas-related gene C (MrgC) receptors. Bioorganic & Medicinal Chemistry. 22: 5831-7. PMID 25288495 DOI: 10.1016/j.bmc.2014.09.025  0.76
2014 Ferraris D, Duvall B, Delahanty G, Mistry B, Alt J, Rojas C, Rowbottom C, Sanders K, Schuck E, Huang KC, Redkar S, Slusher BB, Tsukamoto T. Design, synthesis, and pharmacological evaluation of fluorinated tetrahydrouridine derivatives as inhibitors of cytidine deaminase. Journal of Medicinal Chemistry. 57: 2582-8. PMID 24520856 DOI: 10.1021/jm401856k  0.76
2014 Ferraris DV, Majer P, Ni C, Slusher CE, Rais R, Wu Y, Wozniak KM, Alt J, Rojas C, Slusher BS, Tsukamoto T. δ-Thiolactones as prodrugs of thiol-based glutamate carboxypeptidase II (GCPII) inhibitors. Journal of Medicinal Chemistry. 57: 243-7. PMID 24354364 DOI: 10.1021/jm401703a  0.76
2013 Ferraris D, Yang Z, Welsbie D. Dual leucine zipper kinase as a therapeutic target for neurodegenerative conditions. Future Medicinal Chemistry. 5: 1923-34. PMID 24175744 DOI: 10.4155/fmc.13.150  0.76
2013 Thomas AG, Rojas C, Tanega C, Shen M, Simeonov A, Boxer MB, Auld DS, Ferraris DV, Tsukamoto T, Slusher BS. Kinetic characterization of ebselen, chelerythrine and apomorphine as glutaminase inhibitors. Biochemical and Biophysical Research Communications. 438: 243-8. PMID 23850693 DOI: 10.1016/j.bbrc.2013.06.110  0.76
2013 Raje M, Hin N, Duvall B, Ferraris DV, Berry JF, Thomas AG, Alt J, Rojas C, Slusher BS, Tsukamoto T. Synthesis of kojic acid derivatives as secondary binding site probes of D-amino acid oxidase. Bioorganic & Medicinal Chemistry Letters. 23: 3910-3. PMID 23683589 DOI: 10.1016/j.bmcl.2013.04.062  0.76
2012 Berry JF, Ferraris DV, Duvall B, Hin N, Rais R, Alt J, Thomas AG, Rojas C, Hashimoto K, Slusher BS, Tsukamoto T. Synthesis and SAR of 1-hydroxy-1H-benzo[d]imidazol-2(3H)-ones as Inhibitors of D-Amino Acid Oxidase. Acs Medicinal Chemistry Letters. 3: 839-843. PMID 23243487 DOI: 10.1021/ml300212a  0.76
2012 Shukla K, Ferraris DV, Thomas AG, Stathis M, Duvall B, Delahanty G, Alt J, Rais R, Rojas C, Gao P, Xiang Y, Dang CV, Slusher BS, Tsukamoto T. Design, synthesis, and pharmacological evaluation of bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide 3 (BPTES) analogs as glutaminase inhibitors. Journal of Medicinal Chemistry. 55: 10551-63. PMID 23151085 DOI: 10.1021/jm301191p  0.76
2012 Stoermer D, Vitharana D, Hin N, Delahanty G, Duvall B, Ferraris DV, Grella BS, Hoover R, Rojas C, Shanholtz MK, Smith KP, Stathis M, Wu Y, Wozniak KM, Slusher BS, et al. Design, synthesis, and pharmacological evaluation of glutamate carboxypeptidase II (GCPII) inhibitors based on thioalkylbenzoic acid scaffolds. Journal of Medicinal Chemistry. 55: 5922-32. PMID 22642259 DOI: 10.1021/jm300488m  0.76
2012 Yuneva MO, Fan TW, Allen TD, Higashi RM, Ferraris DV, Tsukamoto T, Matés JM, Alonso FJ, Wang C, Seo Y, Chen X, Bishop JM. The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type. Cell Metabolism. 15: 157-70. PMID 22326218 DOI: 10.1016/j.cmet.2011.12.015  0.76
2012 Ferraris DV, Shukla K, Tsukamoto T. Structure-activity relationships of glutamate carboxypeptidase II (GCPII) inhibitors. Current Medicinal Chemistry. 19: 1282-94. PMID 22304717 DOI: 10.2174/092986712799462658  0.76
2011 Alt J, Rojas C, Wozniak K, Wu Y, Ferraris D, Tsukamoto T, Slusher B. Development of a high-throughput method for the determination of pharmacological levels of plasma D-serine. Analytical Biochemistry. 419: 106-9. PMID 21889486 DOI: 10.1016/j.ab.2011.08.018  0.76
2011 Shukla K, Thomas AG, Ferraris DV, Hin N, Sattler R, Alt J, Rojas C, Slusher BS, Tsukamoto T. Inhibition of xc⁻ transporter-mediated cystine uptake by sulfasalazine analogs. Bioorganic & Medicinal Chemistry Letters. 21: 6184-7. PMID 21889337 DOI: 10.1016/j.bmcl.2011.07.081  0.76
2011 Farah MH, Pan BH, Hoffman PN, Ferraris D, Tsukamoto T, Nguyen T, Wong PC, Price DL, Slusher BS, Griffin JW. Reduced BACE1 activity enhances clearance of myelin debris and regeneration of axons in the injured peripheral nervous system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 5744-54. PMID 21490216 DOI: 10.1523/JNEUROSCI.6810-10.2011  0.76
2011 Ferraris DV, Tsukamoto T. Recent advances in the discovery of D-amino acid oxidase inhibitors and their therapeutic utility in schizophrenia. Current Pharmaceutical Design. 17: 103-11. PMID 21361869 DOI: 10.2174/138161211795049633  0.76
2010 Grella B, Adams J, Berry JF, Delahanty G, Ferraris DV, Majer P, Ni C, Shukla K, Shuler SA, Slusher BS, Stathis M, Tsukamoto T. The discovery and structure-activity relationships of indole-based inhibitors of glutamate carboxypeptidase II. Bioorganic & Medicinal Chemistry Letters. 20: 7222-5. PMID 21074428 DOI: 10.1016/j.bmcl.2010.10.109  0.76
2010 Seltzer MJ, Bennett BD, Joshi AD, Gao P, Thomas AG, Ferraris DV, Tsukamoto T, Rojas CJ, Slusher BS, Rabinowitz JD, Dang CV, Riggins GJ. Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1. Cancer Research. 70: 8981-7. PMID 21045145 DOI: 10.1158/0008-5472.CAN-10-1666  0.76
2010 Ferraris DV. Evolution of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. From concept to clinic. Journal of Medicinal Chemistry. 53: 4561-84. PMID 20364863 DOI: 10.1021/jm100012m  0.76
2009 Hashimoto K, Fujita Y, Horio M, Kunitachi S, Iyo M, Ferraris D, Tsukamoto T. Co-administration of a D-amino acid oxidase inhibitor potentiates the efficacy of D-serine in attenuating prepulse inhibition deficits after administration of dizocilpine. Biological Psychiatry. 65: 1103-6. PMID 19217074 DOI: 10.1016/j.biopsych.2009.01.002  0.76
2009 Horio M, Fujita Y, Ishima T, Iyo M, Ferraris D, Tsukamoto T, Hashimoto K. Effects of D-amino acid oxidase inhibitor on the extracellular D-alanine levels and the efficacy of D-alanine on dizocilpine-induced prepulse inhibition deficits in mice Open Clinical Chemistry Journal. 2: 16-21. DOI: 10.2174/1874241600902010016  0.76
2008 Ferraris D, Duvall B, Ko YS, Thomas AG, Rojas C, Majer P, Hashimoto K, Tsukamoto T. Synthesis and biological evaluation of D-amino acid oxidase inhibitors. Journal of Medicinal Chemistry. 51: 3357-9. PMID 18507366 DOI: 10.1021/jm800200u  0.76
2007 Erdmann N, Zhao J, Lopez AL, Herek S, Curthoys N, Hexum TD, Tsukamoto T, Ferraris D, Zheng J. Glutamate production by HIV-1 infected human macrophage is blocked by the inhibition of glutaminase. Journal of Neurochemistry. 102: 539-49. PMID 17596215 DOI: 10.1111/j.1471-4159.2007.04594.x  0.76
2007 Robinson MM, McBryant SJ, Tsukamoto T, Rojas C, Ferraris DV, Hamilton SK, Hansen JC, Curthoys NP. Novel mechanism of inhibition of rat kidney-type glutaminase by bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES). The Biochemical Journal. 406: 407-14. PMID 17581113 DOI: 10.1042/BJ20070039  0.76
2007 Ferraris D, Belyakov S, Li W, Oliver E, Ko YS, Calvin D, Lautar S, Thomas B, Rojas C. Azetidine-based inhibitors of dipeptidyl peptidase IV (DPP IV). Current Topics in Medicinal Chemistry. 7: 597-608. PMID 17352680 DOI: 10.2174/156802607780090993  0.76
2007 Ferraris D. Catalytic, asymmetric alkylation of imines Tetrahedron. 63: 9581-9597. DOI: 10.1016/j.tet.2007.06.043  0.76
2005 Lautar SL, Rojas C, Slusher BS, Wozniak KM, Wu Y, Thomas AG, Waldon D, Li W, Ferraris D, Belyakov S. DPP IV inhibitor blocks mescaline-induced scratching and amphetamine-induced hyperactivity in mice. Brain Research. 1048: 177-84. PMID 15925329 DOI: 10.1016/j.brainres.2005.04.069  0.76
2005 Perraud AL, Takanishi CL, Shen B, Kang S, Smith MK, Schmitz C, Knowles HM, Ferraris D, Li W, Zhang J, Stoddard BL, Scharenberg AM. Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels. The Journal of Biological Chemistry. 280: 6138-48. PMID 15561722 DOI: 10.1074/jbc.M411446200  0.76
2005 Yates SP, Taylor PL, Jørgensen R, Ferraris D, Zhang J, Andersen GR, Merrill AR. Structure-function analysis of water-soluble inhibitors of the catalytic domain of exotoxin A from Pseudomonas aeruginosa. The Biochemical Journal. 385: 667-75. PMID 15458385 DOI: 10.1042/BJ20041480  0.76
2004 Ferraris D, Ko YS, Calvin D, Chiou T, Lautar S, Thomas B, Wozniak K, Rojas C, Kalish V, Belyakov S. Ketopyrrolidines and ketoazetidines as potent dipeptidyl peptidase IV (DPP IV) inhibitors. Bioorganic & Medicinal Chemistry Letters. 14: 5579-83. PMID 15482928 DOI: 10.1016/j.bmcl.2004.08.057  0.76
2003 Ferraris D, Ficco RP, Dain D, Ginski M, Lautar S, Lee-Wisdom K, Liang S, Lin Q, Lu MX, Morgan L, Thomas B, Williams LR, Zhang J, Zhou Y, Kalish VJ. Design and synthesis of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors. Part 4: biological evaluation of imidazobenzodiazepines as potent PARP-1 inhibitors for treatment of ischemic injuries. Bioorganic & Medicinal Chemistry. 11: 3695-707. PMID 12901915 DOI: 10.1016/S0968-0896(03)00333-X  0.76
2003 Ferraris D, Ficco RP, Pahutski T, Lautar S, Huang S, Zhang J, Kalish V. Design and synthesis of poly(ADP-ribose)polymerase-1 (PARP-1) inhibitors. Part 3: In vitro evaluation of 1,3,4,5-tetrahydro-benzo[c][1,6]- and [c][1,7]-naphthyridin-6-ones. Bioorganic & Medicinal Chemistry Letters. 13: 2513-8. PMID 12852955 DOI: 10.1002/chin.200344132  0.76
2003 Ferraris D, Ko YS, Pahutski T, Ficco RP, Serdyuk L, Alemu C, Bradford C, Chiou T, Hoover R, Huang S, Lautar S, Liang S, Lin Q, Lu MX, Mooney M, et al. Design and synthesis of poly ADP-ribose polymerase-1 inhibitors. 2. Biological evaluation of aza-5[H]-phenanthridin-6-ones as potent, aqueous-soluble compounds for the treatment of ischemic injuries. Journal of Medicinal Chemistry. 46: 3138-51. PMID 12825952 DOI: 10.1021/jm030109s  0.76
2002 Taggi AE, Hafez AM, Wack H, Young B, Ferraris D, Lectka T. The development of the first catalyzed reaction of ketenes and imines: catalytic, asymmetric synthesis of beta-lactams. Journal of the American Chemical Society. 124: 6626-35. PMID 12047183 DOI: 10.1021/ja0258226  0.76
2002 Ferraris D, Young B, Cox C, Dudding T, Drury WJ, Ryzhkov L, Taggi AE, Lectka T. Catalytic, enantioselective alkylation of alpha-imino esters: the synthesis of nonnatural alpha-amino acid derivatives. Journal of the American Chemical Society. 124: 67-77. PMID 11772063 DOI: 10.1021/ja016838j  0.76
2002 Stone MB, Chen Y, Rittner J, Yardimci H, Reich DH, Broholm C, Ferraris DV, Lectka T. Frustrated three-dimensional quantum spin liquid in CuHpCl Physical Review B - Condensed Matter and Materials Physics. 65: 644231-6442312.  0.76
2001 Li JH, Serdyuk L, Ferraris DV, Xiao G, Tays KL, Kletzly PW, Li W, Lautar S, Zhang J, Kalish VJ. Synthesis of substituted 5[H]phenanthridin-6-ones as potent poly(ADP-ribose)polymerase-1 (PARP1) inhibitors. Bioorganic & Medicinal Chemistry Letters. 11: 1687-90. PMID 11425538 DOI: 10.1016/S0960-894X(01)00281-5  0.76
1999 Wack H, Drury WJ, Taggi AE, Ferraris D, Lectka T. Nucleophilic metal complexes as acylation catalysts: solvent-dependent "switch" mechanisms leading to the first catalyzed Staudinger reaction. Organic Letters. 1: 1985-8. PMID 10836055  0.76
1999 Ferraris D, Dudding T, Young B, Drury WJ, Lectka T. Catalytic, enantioselective alkylations of N,O-acetals Journal of Organic Chemistry. 64: 2168-2169. DOI: 10.1021/jo982421t  0.76
1999 Ferraris D, Young B, Dudding T, Drury WJ, Lectka T. Catalytic, enantioselective alkylations of N,O- and N,N-acetals and hemiacetals Tetrahedron. 55: 8869-8882. DOI: 10.1016/S0040-4020(99)00450-0  0.76
1998 Ferraris D, Young B, Cox C, Drury III WJ, Dudding T, Lectka T. Diastereo- and Enantioselective Alkylation of alpha-Imino Esters with Enol Silanes Catalyzed by (R)-Tol-BINAP-CuClO(4).(MeCN)(2). The Journal of Organic Chemistry. 63: 6090-6091. PMID 11672229  0.76
1998 Drury WJ, Ferraris D, Cox C, Young B, Lectka T. A novel synthesis of α-amino acid derivatives through catalytic, enantioselective ene reactions of α-imino esters [16] Journal of the American Chemical Society. 120: 11006-11007. DOI: 10.1021/ja982257r  0.76
1998 Ferraris D, Young B, Dudding T, Lectka T. Catalytic, enantioselective alkylation of α-imino esters using late transition metal phosphine complexes as catalysts Journal of the American Chemical Society. 120: 4548-4549. DOI: 10.1021/ja9802450  0.76
1998 Ferraris D, Drury WJ, Cox C, Lectka T. "Orthogonal" Lewis Acids: Catalyzed Ring Opening and Rearrangement of Acylaziridines Journal of Organic Chemistry. 63: 4568-4569.  0.76
1997 Ferraris D, Cox C, Anand R, Lectka T. C-F bond activation by aryl carbocations: Conclusive intramolecular fluoride shifts between carbon atoms in solution and the first examples of intermolecular fluoride ion abstractions Journal of the American Chemical Society. 119: 4319-4320. DOI: 10.1021/ja963090+  0.76
1996 Cox C, Ferraris D, Murthy NN, Lectka T. Copper(II)-catalyzed amide isomerization: Evidence for N-coordination Journal of the American Chemical Society. 118: 5332-5333. DOI: 10.1021/ja960693c  0.76
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