German A. Gomez, Ph.D. - Publications

Affiliations: 
2006 University of Pennsylvania, Philadelphia, PA, United States 
Area:
structure-mechanism of hydrolytic metalloenzymes

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Michael M, Meiring JC, Acharya BR, Matthews DR, Verma S, Han SP, Hill MM, Parton RG, Gomez GA, Yap AS. Coronin 1B Reorganizes the Architecture of F-Actin Networks for Contractility at Steady-State and Apoptotic Adherens Junctions. Developmental Cell. 37: 58-71. PMID 27046832 DOI: 10.1016/j.devcel.2016.03.008  0.01
2016 Leung AW, Murdoch B, Salem AF, Prasad MS, Gomez GA, García-Castro MI. WNT/β-catenin signaling mediates human neural crest induction via a pre-neural border intermediate. Development (Cambridge, England). 143: 398-410. PMID 26839343 DOI: 10.1242/dev.130849  0.01
2015 Kubala MH, Norwood SJ, Gomez GA, Jones A, Johnston W, Yap AS, Mureev S, Alexandrov K. Mammalian Farnesyltransferase α Subunit Regulates Vacuolar Protein Sorting-Associated Protein 4A (Vps4A) - Dependent Intracellular Trafficking Through Recycling Endosomes. Biochemical and Biophysical Research Communications. PMID 26551458 DOI: 10.1016/J.Bbrc.2015.10.148  0.01
2015 Yap AS, Gomez GA, Parton RG. Adherens Junctions Revisualized: Organizing Cadherins as Nanoassemblies. Developmental Cell. 35: 12-20. PMID 26460944 DOI: 10.1016/j.devcel.2015.09.012  0.01
2015 Priya R, Gomez GA, Budnar S, Verma S, Cox HL, Hamilton NA, Yap AS. Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions. Nature Cell Biology. 17: 1282-93. PMID 26368311 DOI: 10.1038/Ncb3239  0.01
2015 R Noppe A, Roberts AP, Yap AS, Gomez GA, Neufeld Z. Modelling wound closure in an epithelial cell sheet using the cellular Potts model. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 26119963 DOI: 10.1039/c5ib00053j  0.01
2015 Han S, Englander EW, Gomez GA, Rastellini C, Quertermous T, Kundu RK, Greeley GH. Pancreatic Islet APJ Deletion Reduces Islet Density and Glucose Tolerance in Mice. Endocrinology. 156: 2451-60. PMID 25965959 DOI: 10.1210/en.2014-1631  0.01
2015 Papadopulos A, Gomez GA, Martin S, Jackson J, Gormal RS, Keating DJ, Yap AS, Meunier FA. Activity-driven relaxation of the cortical actomyosin II network synchronizes Munc18-1-dependent neurosecretory vesicle docking. Nature Communications. 6: 6297. PMID 25708831 DOI: 10.1038/ncomms7297  0.01
2015 Gomez GA, McLachlan RW, Wu SK, Caldwell BJ, Moussa E, Verma S, Bastiani M, Priya R, Parton RG, Gaus K, Sap J, Yap AS. An RPTPα/Src family kinase/Rap1 signaling module recruits myosin IIB to support contractile tension at apical E-cadherin junctions. Molecular Biology of the Cell. 26: 1249-62. PMID 25631816 DOI: 10.1091/mbc.E14-07-1223  0.01
2015 Wu SK, Lagendijk AK, Hogan BM, Gomez GA, Yap AS. Active contractility at E-cadherin junctions and its implications for cell extrusion in cancer. Cell Cycle (Georgetown, Tex.). 14: 315-22. PMID 25590779 DOI: 10.4161/15384101.2014.989127  0.01
2014 Caldwell BJ, Lucas C, Kee AJ, Gaus K, Gunning PW, Hardeman EC, Yap AS, Gomez GA. Tropomyosin isoforms support actomyosin biogenesis to generate contractile tension at the epithelial zonula adherens. Cytoskeleton (Hoboken, N.J.). 71: 663-76. PMID 25545457 DOI: 10.1002/cm.21202  0.01
2014 Moore T, Wu SK, Michael M, Yap AS, Gomez GA, Neufeld Z. Self-organizing actomyosin patterns on the cell cortex at epithelial cell-cell junctions. Biophysical Journal. 107: 2652-61. PMID 25468344 DOI: 10.1016/j.bpj.2014.10.045  0.01
2014 Wu SK, Budnar S, Yap AS, Gomez GA. Pulsatile contractility of actomyosin networks organizes the cellular cortex at lateral cadherin junctions. European Journal of Cell Biology. 93: 396-404. PMID 25269995 DOI: 10.1016/j.ejcb.2014.09.001  0.01
2014 Leerberg JM, Gomez GA, Verma S, Moussa EJ, Wu SK, Priya R, Hoffman BD, Grashoff C, Schwartz MA, Yap AS. Tension-sensitive actin assembly supports contractility at the epithelial zonula adherens. Current Biology : Cb. 24: 1689-99. PMID 25065757 DOI: 10.1016/J.Cub.2014.06.028  0.01
2014 Brooks AJ, Dai W, O'Mara ML, Abankwa D, Chhabra Y, Pelekanos RA, Gardon O, Tunny KA, Blucher KM, Morton CJ, Parker MW, Sierecki E, Gambin Y, Gomez GA, Alexandrov K, et al. Mechanism of activation of protein kinase JAK2 by the growth hormone receptor. Science (New York, N.Y.). 344: 1249783. PMID 24833397 DOI: 10.1126/Science.1249783  0.01
2014 Chaudhary N, Gomez GA, Howes MT, Lo HP, McMahon KA, Rae JA, Schieber NL, Hill MM, Gaus K, Yap AS, Parton RG. Endocytic crosstalk: cavins, caveolins, and caveolae regulate clathrin-independent endocytosis. Plos Biology. 12: e1001832. PMID 24714042 DOI: 10.1371/journal.pbio.1001832  0.01
2014 Truffi M, Dubreuil V, Liang X, Vacaresse N, Nigon F, Han SP, Yap AS, Gomez GA, Sap J. RPTPα controls epithelial adherens junctions, linking E-cadherin engagement to c-Src-mediated phosphorylation of cortactin. Journal of Cell Science. 127: 2420-32. PMID 24652832 DOI: 10.1242/jcs.134379  0.01
2014 Barry AK, Tabdili H, Muhamed I, Wu J, Shashikanth N, Gomez GA, Yap AS, Gottardi CJ, de Rooij J, Wang N, Leckband DE. α-catenin cytomechanics--role in cadherin-dependent adhesion and mechanotransduction. Journal of Cell Science. 127: 1779-91. PMID 24522187 DOI: 10.1242/Jcs.139014  0.01
2014 Han SP, Gambin Y, Gomez GA, Verma S, Giles N, Michael M, Wu SK, Guo Z, Johnston W, Sierecki E, Parton RG, Alexandrov K, Yap AS. Cortactin scaffolds Arp2/3 and WAVE2 at the epithelial zonula adherens. The Journal of Biological Chemistry. 289: 7764-75. PMID 24469447 DOI: 10.1074/Jbc.M113.544478  0.01
2014 Wu SK, Gomez GA, Michael M, Verma S, Cox HL, Lefevre JG, Parton RG, Hamilton NA, Neufeld Z, Yap AS. Cortical F-actin stabilization generates apical-lateral patterns of junctional contractility that integrate cells into epithelia. Nature Cell Biology. 16: 167-78. PMID 24413434 DOI: 10.1038/Ncb2900  0.01
2014 Cameron AR, Frith JE, Gomez GA, Yap AS, Cooper-White JJ. The effect of time-dependent deformation of viscoelastic hydrogels on myogenic induction and Rac1 activity in mesenchymal stem cells. Biomaterials. 35: 1857-68. PMID 24331708 DOI: 10.1016/j.biomaterials.2013.11.023  0.01
2013 Pedro MP, Vilcaes AA, Tomatis VM, Oliveira RG, Gomez GA, Daniotti JL. 2-Bromopalmitate reduces protein deacylation by inhibition of acyl-protein thioesterase enzymatic activities. Plos One. 8: e75232. PMID 24098372 DOI: 10.1371/journal.pone.0075232  0.01
2013 Veldman MB, Zhao C, Gomez GA, Lindgren AG, Huang H, Yang H, Yao S, Martin BL, Kimelman D, Lin S. Transdifferentiation of fast skeletal muscle into functional endothelium in vivo by transcription factor Etv2. Plos Biology. 11: e1001590. PMID 23853546 DOI: 10.1371/Journal.Pbio.1001590  0.01
2013 Han S, Englander EW, Gomez GA, Aronson JF, Rastellini C, Garofalo RP, Kolli D, Quertermous T, Kundu R, Greeley GH. Pancreatitis activates pancreatic apelin-APJ axis in mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 305: G139-50. PMID 23681476 DOI: 10.1152/Ajpgi.00370.2012  0.01
2013 Priya R, Yap AS, Gomez GA. E-cadherin supports steady-state Rho signaling at the epithelial zonula adherens. Differentiation; Research in Biological Diversity. 86: 133-40. PMID 23643492 DOI: 10.1016/j.diff.2013.01.002  0.01
2012 Verma S, Han SP, Michael M, Gomez GA, Yang Z, Teasdale RD, Ratheesh A, Kovacs EM, Ali RG, Yap AS. A WAVE2-Arp2/3 actin nucleator apparatus supports junctional tension at the epithelial zonula adherens. Molecular Biology of the Cell. 23: 4601-10. PMID 23051739 DOI: 10.1091/mbc.E12-08-0574  0.01
2012 Ratheesh A, Gomez GA, Priya R, Verma S, Kovacs EM, Jiang K, Brown NH, Akhmanova A, Stehbens SJ, Yap AS. Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens. Nature Cell Biology. 14: 818-28. PMID 22750944 DOI: 10.1038/ncb2532  0.01
2012 Ferrari ML, Gomez GA, Maccioni HJ. Spatial organization and stoichiometry of N-terminal domain-mediated glycosyltransferase complexes in Golgi membranes determined by fret microscopy. Neurochemical Research. 37: 1325-34. PMID 22388569 DOI: 10.1007/s11064-012-0741-1  0.01
2012 Chao C, Carmical JR, Ives KL, Wood TG, Aronson JF, Gomez GA, Djukom CD, Hellmich MR. CD133+ colon cancer cells are more interactive with the tumor microenvironment than CD133- cells. Laboratory Investigation; a Journal of Technical Methods and Pathology. 92: 420-36. PMID 22157717 DOI: 10.1038/Labinvest.2011.185  0.01
2011 Smutny M, Wu SK, Gomez GA, Mangold S, Yap AS, Hamilton NA. Multicomponent analysis of junctional movements regulated by myosin II isoforms at the epithelial zonula adherens. Plos One. 6: e22458. PMID 21799860 DOI: 10.1371/Journal.Pone.0022458  0.01
2011 Gomez GA, McLachlan RW, Yap AS. Productive tension: force-sensing and homeostasis of cell-cell junctions. Trends in Cell Biology. 21: 499-505. PMID 21763139 DOI: 10.1016/j.tcb.2011.05.006  0.01
2011 Levingston Macleod JM, D'Antuono A, Loureiro ME, Casabona JC, Gomez GA, Lopez N. Identification of two functional domains within the arenavirus nucleoprotein. Journal of Virology. 85: 2012-23. PMID 21159858 DOI: 10.1128/JVI.01875-10  0.01
2010 Tomatis VM, Trenchi A, Gomez GA, Daniotti JL. Acyl-protein thioesterase 2 catalyzes the deacylation of peripheral membrane-associated GAP-43. Plos One. 5: e15045. PMID 21152083 DOI: 10.1371/journal.pone.0015045  0.01
2010 Ren X, Gomez GA, Zhang B, Lin S. Scl isoforms act downstream of etsrp to specify angioblasts and definitive hematopoietic stem cells. Blood. 115: 5338-46. PMID 20185582 DOI: 10.1182/blood-2009-09-244640  0.01
2009 Trenchi A, Gomez GA, Daniotti JL. Dual acylation is required for trafficking of growth-associated protein-43 (GAP-43) to endosomal recycling compartment via an Arf6-associated endocytic vesicular pathway. The Biochemical Journal. 421: 357-69. PMID 19442238 DOI: 10.1042/BJ20090484  0.01
2009 Casabona JC, Levingston Macleod JM, Loureiro ME, Gomez GA, Lopez N. The RING domain and the L79 residue of Z protein are involved in both the rescue of nucleocapsids and the incorporation of glycoproteins into infectious chimeric arenavirus-like particles. Journal of Virology. 83: 7029-39. PMID 19420075 DOI: 10.1128/JVI.00329-09  0.01
2009 Gomez GA, Veldman MB, Zhao Y, Burgess S, Lin S. Discovery and characterization of novel vascular and hematopoietic genes downstream of etsrp in zebrafish. Plos One. 4: e4994. PMID 19308258 DOI: 10.1371/Journal.Pone.0004994  0.01
2008 Singh A, Alperin JB, Gomez GA, Loop K, Hudnall SD, Cass AR, Raju GS. Mucosal associated lymphoid tissue lymphoma of the colon presenting as autoimmune hemolytic anemia (with video). Gastrointestinal Endoscopy. 67: 1175-6; discussion 1. PMID 18355818 DOI: 10.1016/j.gie.2007.12.027  0.01
2007 Gomez GA, Daniotti JL. Electrical properties of plasma membrane modulate subcellular distribution of K-Ras. The Febs Journal. 274: 2210-28. PMID 17388810 DOI: 10.1111/j.1742-4658.2007.05758.x  0.01
2007 De Vivo M, Ensing B, Dal Peraro M, Gomez GA, Christianson DW, Klein ML. Proton shuttles and phosphatase activity in soluble epoxide hydrolase. Journal of the American Chemical Society. 129: 387-94. PMID 17212419 DOI: 10.1021/Ja066150C  0.56
2007 Di Costanzo L, Gomez GA, Christianson DW. Crystal structure of lactaldehyde dehydrogenase from Escherichia coli and inferences regarding substrate and cofactor specificity. Journal of Molecular Biology. 366: 481-93. PMID 17173928 DOI: 10.1016/J.Jmb.2006.11.023  0.56
2006 Iglesias-Bartolomé R, Crespo PM, Gomez GA, Daniotti JL. The antibody to GD3 ganglioside, R24, is rapidly endocytosed and recycled to the plasma membrane via the endocytic recycling compartment. Inhibitory effect of brefeldin A and monensin. The Febs Journal. 273: 1744-58. PMID 16623710 DOI: 10.1111/j.1742-4658.2006.05194.x  0.01
2006 Gomez GA, Morisseau C, Hammock BD, Christianson DW. Human soluble epoxide hydrolase: structural basis of inhibition by 4-(3-cyclohexylureido)-carboxylic acids. Protein Science : a Publication of the Protein Society. 15: 58-64. PMID 16322563 DOI: 10.1110/Ps.051720206  0.56
2005 Gomez GA, Daniotti JL. H-Ras dynamically interacts with recycling endosomes in CHO-K1 cells: involvement of Rab5 and Rab11 in the trafficking of H-Ras to this pericentriolar endocytic compartment. The Journal of Biological Chemistry. 280: 34997-5010. PMID 16079139 DOI: 10.1074/jbc.M506256200  0.01
2004 Englander EW, Gomez GA, Greeley GH. Alterations in stomach ghrelin production and in ghrelin-induced growth hormone secretion in the aged rat. Mechanisms of Ageing and Development. 125: 871-5. PMID 15563933 DOI: 10.1016/j.mad.2004.06.011  0.01
2004 Gomez GA, Morisseau C, Hammock BD, Christianson DW. Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis. Biochemistry. 43: 4716-23. PMID 15096040 DOI: 10.1021/Bi036189J  0.56
2002 Naoum JJ, Mileski WJ, Daller JA, Gomez GA, Gore DC, Kimbrough TD, Ko TC, Sanford AP, Wolf SE. The use of abdominal computed tomography scan decreases the frequency of misdiagnosis in cases of suspected appendicitis. American Journal of Surgery. 184: 587-9; discussion 58. PMID 12488178 DOI: 10.1016/S0002-9610(02)01086-3  0.01
1986 Gomez GA. Fatal complications from combined modality therapy in Hodgkin's disease: age is not a risk factor. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 4: 114-5. PMID 3941330  0.01
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