Kevin Jude, Ph.D. - Publications

Affiliations: 
2007 University of Pennsylvania, Philadelphia, PA, United States 
Area:
structure-mechanism of hydrolytic metalloenzymes

13/27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Weiskopf K, Jahchan NS, Schnorr PJ, Cristea S, Ring AM, Maute RL, Volkmer AK, Volkmer JP, Liu J, Lim JS, Yang D, Seitz G, Nguyen T, Wu D, Jude K, et al. CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer. The Journal of Clinical Investigation. PMID 27294525 DOI: 10.1172/JCI81603  0.48
2015 Moraga I, Richter D, Wilmes S, Winkelmann H, Jude K, Thomas C, Suhoski MM, Engleman EG, Piehler J, Garcia KC. Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency. Science Signaling. 8: ra114. PMID 26554818 DOI: 10.1126/scisignal.aab2677  0.48
2015 Spangler JB, Tomala J, Luca VC, Jude KM, Dong S, Ring AM, Votavova P, Pepper M, Kovar M, Garcia KC. Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms. Immunity. 42: 815-25. PMID 25992858 DOI: 10.1016/j.immuni.2015.04.015  0.48
2015 Burg JS, Ingram JR, Venkatakrishnan AJ, Jude KM, Dukkipati A, Feinberg EN, Angelini A, Waghray D, Dror RO, Ploegh HL, Garcia KC. Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor. Science (New York, N.Y.). 347: 1113-7. PMID 25745166 DOI: 10.1126/science.aaa5026  0.48
2015 Luca VC, Jude KM, Pierce NW, Nachury MV, Fischer S, Garcia KC. Structural biology. Structural basis for Notch1 engagement of Delta-like 4. Science (New York, N.Y.). 347: 847-53. PMID 25700513 DOI: 10.1126/science.1261093  0.48
2013 Jude KM, Hartland A, Berger JM. Real-time detection of DNA topological changes with a fluorescently labeled cruciform. Nucleic Acids Research. 41: e133. PMID 23680786 DOI: 10.1093/nar/gkt413  0.48
2009 Hanes MS, Jude KM, Berger JM, Bonomo RA, Handel TM. Structural and biochemical characterization of the interaction between KPC-2 beta-lactamase and beta-lactamase inhibitor protein. Biochemistry. 48: 9185-93. PMID 19731932 DOI: 10.1021/bi9007963  0.48
2008 Aaron JA, Chambers JM, Jude KM, Di Costanzo L, Dmochowski IJ, Christianson DW. Structure of a 129Xe-cryptophane biosensor complexed with human carbonic anhydrase II. Journal of the American Chemical Society. 130: 6942-3. PMID 18461940 DOI: 10.1021/ja802214x  0.48
2007 Srivastava DK, Jude KM, Banerjee AL, Haldar M, Manokaran S, Kooren J, Mallik S, Christianson DW. Structural analysis of charge discrimination in the binding of inhibitors to human carbonic anhydrases I and II. Journal of the American Chemical Society. 129: 5528-37. PMID 17407288 DOI: 10.1021/ja068359w  0.48
2006 Jude KM, Banerjee AL, Haldar MK, Manokaran S, Roy B, Mallik S, Srivastava DK, Christianson DW. Ultrahigh resolution crystal structures of human carbonic anhydrases I and II complexed with "two-prong" inhibitors reveal the molecular basis of high affinity. Journal of the American Chemical Society. 128: 3011-8. PMID 16506782 DOI: 10.1021/ja057257n  0.48
2005 Colleluori DM, Reczkowski RS, Emig FA, Cama E, Cox JD, Scolnick LR, Compher K, Jude K, Han S, Viola RE, Christianson DW, Ash DE. Probing the role of the hyper-reactive histidine residue of arginase. Archives of Biochemistry and Biophysics. 444: 15-26. PMID 16266687 DOI: 10.1016/j.abb.2005.09.009  0.48
2002 Jude KM, Wright SK, Tu C, Silverman DN, Viola RE, Christianson DW. Crystal structure of F65A/Y131C-methylimidazole carbonic anhydrase V reveals architectural features of an engineered proton shuttle. Biochemistry. 41: 2485-91. PMID 11851394 DOI: 10.1021/bi015808q  0.48
1998 Presnell SR, Patil GS, Mura C, Jude KM, Conley JM, Bertrand JA, Kam CM, Powers JC, Williams LD. Oxyanion-mediated inhibition of serine proteases. Biochemistry. 37: 17068-81. PMID 9836602 DOI: 10.1021/bi981636u  0.48
Low-probability matches
2019 Spangler JB, Moraga I, Jude KM, Savvides CS, Garcia KC. A strategy for the selection of monovalent antibodies that span protein dimer interfaces. The Journal of Biological Chemistry. PMID 31387945 DOI: 10.1074/jbc.RA119.009213  0.01
2019 Mohan K, Ueda G, Kim AR, Jude KM, Fallas JA, Guo Y, Hafer M, Miao Y, Saxton RA, Piehler J, Sankaran VG, Baker D, Garcia KC. Topological control of cytokine receptor signaling induces differential effects in hematopoiesis. Science (New York, N.Y.). 364. PMID 31123111 DOI: 10.1126/science.aav7532  0.01
2019 Dang LT, Miao Y, Ha A, Yuki K, Park K, Janda CY, Jude KM, Mohan K, Ha N, Vallon M, Yuan J, Vilches-Moure JG, Kuo CJ, Garcia KC, Baker D. Receptor subtype discrimination using extensive shape complementary designed interfaces. Nature Structural & Molecular Biology. PMID 31086346 DOI: 10.1038/s41594-019-0224-z  0.01
2019 Mendoza JL, Escalante NK, Jude KM, Sotolongo Bellon J, Su L, Horton TM, Tsutsumi N, Berardinelli SJ, Haltiwanger RS, Piehler J, Engleman EG, Garcia KC. Structure of the IFNγ receptor complex guides design of biased agonists. Nature. PMID 30814731 DOI: 10.1038/s41586-019-0988-7  0.01
2019 Silva DA, Yu S, Ulge UY, Spangler JB, Jude KM, Labão-Almeida C, Ali LR, Quijano-Rubio A, Ruterbusch M, Leung I, Biary T, Crowley SJ, Marcos E, Walkey CD, Weitzner BD, et al. De novo design of potent and selective mimics of IL-2 and IL-15. Nature. 565: 186-191. PMID 30626941 DOI: 10.1038/s41586-018-0830-7  0.01
2018 Sibener LV, Fernandes RA, Kolawole EM, Carbone CB, Liu F, McAffee D, Birnbaum ME, Yang X, Su LF, Yu W, Dong S, Gee MH, Jude KM, Davis MM, Groves JT, et al. Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding. Cell. 174: 672-687.e27. PMID 30053426 DOI: 10.1016/j.cell.2018.06.017  0.01
2018 Gee MH, Sibener LV, Birnbaum ME, Jude KM, Yang X, Fernandes RA, Mendoza JL, Glassman CR, Garcia KC. Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro. Proceedings of the National Academy of Sciences of the United States of America. PMID 30021852 DOI: 10.1073/pnas.1802746115  0.01
2018 Trotta E, Bessette PH, Silveria SL, Ely LK, Jude KM, Le DT, Holst CR, Coyle A, Potempa M, Lanier LL, Garcia KC, Crellin NK, Rondon IJ, Bluestone JA. A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism. Nature Medicine. PMID 29942088 DOI: 10.1038/s41591-018-0070-2  0.01
2018 Miles TF, Spiess K, Jude KM, Tsutsumi N, Burg JS, Ingram JR, Waghray D, Hjorto GM, Larsen O, Ploegh HL, Rosenkilde MM, Garcia KC. Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy. Elife. 7. PMID 29882741 DOI: 10.7554/eLife.35850  0.01
2018 Sockolosky JT, Trotta E, Parisi G, Picton L, Su LL, Le AC, Chhabra A, Silveria SL, George BM, King IC, Tiffany MR, Jude K, Sibener LV, Baker D, Shizuru JA, et al. Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes. Science (New York, N.Y.). 359: 1037-1042. PMID 29496879 DOI: 10.1126/science.aar3246  0.01
2017 Mendoza JL, Schneider WM, Hoffmann HH, Vercauteren K, Jude KM, Xiong A, Moraga I, Horton TM, Glenn JS, de Jong YP, Rice CM, Garcia KC. The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity. Immunity. 46: 379-392. PMID 28329704 DOI: 10.1016/j.immuni.2017.02.017  0.01
2013 Hellwig T, Jude K, Meyer B. Management options for infectious mononucleosis U.S. Pharmacist. 38.  0.01
2012 Hall L, Jude KP, Clark SL, Dionne K, Merson R, Boyer A, Parrish NM, Wengenack NL. Evaluation of the Sensititre MycoTB plate for susceptibility testing of the Mycobacterium tuberculosis complex against first- and second-line agents. Journal of Clinical Microbiology. 50: 3732-4. PMID 22895034 DOI: 10.1128/JCM.02048-12  0.01
2011 Hall L, Jude KP, Clark SL, Wengenack NL. Antimicrobial susceptibility testing of Mycobacterium tuberculosis complex for first and second line drugs by broth dilution in a microtiter plate format. Journal of Visualized Experiments : Jove. PMID 21730945 DOI: 10.3791/3094  0.01
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