Patrick M. Lombardi, Ph.D. - Publications

Johns Hopkins University School of Medicine, Baltimore, MD, United States 
structure-mechanism of hydrolytic metalloenzymes

8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Brickner JR, Soll JM, Lombardi PM, Vågbø CB, Mudge MC, Oyeniran C, Rabe R, Jackson J, Sullender ME, Blazosky E, Byrum AK, Zhao Y, Corbett MA, Gécz J, Field M, et al. A ubiquitin-dependent signalling axis specific for ALKBH-mediated DNA dealkylation repair. Nature. 551: 389-393. PMID 29144457 DOI: 10.1038/Nature24484  1
2017 Lombardi PM, Matunis MJ, Wolberger C. RAP80, ubiquitin and SUMO in the DNA damage response. Journal of Molecular Medicine (Berlin, Germany). PMID 28681078 DOI: 10.1007/S00109-017-1561-1  1
2015 Harris GG, Lombardi PM, Pemberton TA, Matsui T, Weiss TM, Cole KE, Köksal M, Murphy FV, Vedula LS, Chou WK, Cane DE, Christianson DW. Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with αα Domain Architecture That Catalyzes a Unique Cyclization-Fragmentation Reaction Sequence. Biochemistry. PMID 26598179 DOI: 10.1021/Acs.Biochem.5B01143  1
2013 Wiener R, DiBello AT, Lombardi PM, Guzzo CM, Zhang X, Matunis MJ, Wolberger C. E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1. Nature Structural & Molecular Biology. 20: 1033-9. PMID 23955022 DOI: 10.1038/Nsmb.2655  1
2012 Deardorff MA, Bando M, Nakato R, Watrin E, Itoh T, Minamino M, Saitoh K, Komata M, Katou Y, Clark D, Cole KE, De Baere E, Decroos C, Di Donato N, Ernst S, ... ... Lombardi PM, et al. HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle. Nature. 489: 313-7. PMID 22885700 DOI: 10.1038/Nature11316  1
2011 Ilies M, Dowling DP, Lombardi PM, Christianson DW. Synthesis of a new trifluoromethylketone analogue of l-arginine and contrasting inhibitory activity against human arginase I and histone deacetylase 8. Bioorganic & Medicinal Chemistry Letters. 21: 5854-8. PMID 21875805 DOI: 10.1016/J.Bmcl.2011.07.100  1
2011 Lombardi PM, Cole KE, Dowling DP, Christianson DW. Structure, mechanism, and inhibition of histone deacetylases and related metalloenzymes. Current Opinion in Structural Biology. 21: 735-43. PMID 21872466 DOI: 10.1016/J.Sbi.2011.08.004  1
2011 Lombardi PM, Angell HD, Whittington DA, Flynn EF, Rajashankar KR, Christianson DW. Structure of prokaryotic polyamine deacetylase reveals evolutionary functional relationships with eukaryotic histone deacetylases. Biochemistry. 50: 1808-17. PMID 21268586 DOI: 10.1021/Bi101859K  1
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