Erik W. Debler, Ph.D. - Publications

Affiliations: 
2006 Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Structural biology, immunology, X-ray crystallography

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Hashimoto H, Ramirez DH, Lautier O, Pawlak N, Blobel G, Palancade B, Debler EW. Structure of the pre-mRNA leakage 39-kDa protein reveals a single domain of integrated zf-C3HC and Rsm1 modules. Scientific Reports. 12: 17691. PMID 36271106 DOI: 10.1038/s41598-022-22183-3  0.519
2022 Long T, Debler EW, Li X. Structural enzymology of cholesterol biosynthesis and storage. Current Opinion in Structural Biology. 74: 102369. PMID 35398802 DOI: 10.1016/j.sbi.2022.102369  0.417
2019 Hashimoto H, Kafková L, Raczkowski A, Jordan KD, Read LK, Debler EW. Structural Basis of Protein Arginine Methyltransferase Activation by a Catalytically Dead Homolog (Prozyme). Journal of Molecular Biology. PMID 31726063 DOI: 10.1016/J.Jmb.2019.11.002  0.479
2019 Blus BJ, Hashimoto H, Seo HS, Krolak A, Debler EW. Substrate Affinity and Specificity of the ScSth1p Bromodomain Are Fine-Tuned for Versatile Histone Recognition. Structure (London, England : 1993). PMID 31327661 DOI: 10.1016/J.Str.2019.06.009  0.399
2019 Noell CR, Loh JY, Debler EW, Loftus KM, Cui H, Russ BB, Zhang K, Goyal P, Solmaz SR. Role of Coiled-coil Registry Shifts in Activation of Human Bicaudal D2 for Dynein Recruitment Upon Cargo-Binding. The Journal of Physical Chemistry Letters. PMID 31306018 DOI: 10.1021/Acs.Jpclett.9B01865  0.395
2018 Kafková L, Tu C, Pazzo KL, Smith KP, Debler EW, Paul KS, Qu J, Read LK. Trypanosoma brucei PRMT1 Is a Nucleic Acid Binding Protein with a Role in Energy Metabolism and the Starvation Stress Response. Mbio. 9. PMID 30563898 DOI: 10.1128/Mbio.02430-18  0.315
2018 Noell CR, Loftus KM, Cui H, Grewer CT, Kizer M, Debler EW, Solmaz SR. A quantitative model for BicD2/cargo interactions. Biochemistry. PMID 30345745 DOI: 10.1021/Acs.Biochem.8B00987  0.328
2016 Kafkova L, Debler EW, Fisk JC, Jain K, Clarke SG, Read LK. The Major Protein Arginine Methyltransferase in Trypanosoma brucei Functions as an Enzyme-Prozyme Complex. The Journal of Biological Chemistry. PMID 27998975 DOI: 10.1074/Jbc.M116.757112  0.335
2016 Jain K, Warmack RA, Debler EW, Hadjikyriacou A, Stavropoulos P, Clarke SG. Protein Arginine Methyltransferase Product Specificity is Mediated by Distinct Active-Site Architectures. The Journal of Biological Chemistry. PMID 27387499 DOI: 10.1074/Jbc.M116.740399  0.352
2016 Debler EW, Jain K, Warmack RA, Feng Y, Clarke SG, Blobel G, Stavropoulos P. A glutamate/aspartate switch controls product specificity in a protein arginine methyltransferase. Proceedings of the National Academy of Sciences of the United States of America. PMID 26858449 DOI: 10.1073/Pnas.1525783113  0.529
2015 Schulz D, Mugnier MR, Paulsen EM, Kim HS, Chung CW, Tough DF, Rioja I, Prinjha RK, Papavasiliou FN, Debler EW. Bromodomain Proteins Contribute to Maintenance of Bloodstream Form Stage Identity in the African Trypanosome. Plos Biology. 13: e1002316. PMID 26646171 DOI: 10.1371/Journal.Pbio.1002316  0.348
2011 Yoshida K, Seo HS, Debler EW, Blobel G, Hoelz A. Structural and functional analysis of an essential nucleoporin heterotrimer on the cytoplasmic face of the nuclear pore complex. Proceedings of the National Academy of Sciences of the United States of America. 108: 16571-6. PMID 21930948 DOI: 10.1073/Pnas.1112846108  0.59
2011 Hoelz A, Debler EW, Blobel G. The structure of the nuclear pore complex. Annual Review of Biochemistry. 80: 613-43. PMID 21495847 DOI: 10.1146/Annurev-Biochem-060109-151030  0.55
2010 Debler EW, Hsia KC, Nagy V, Seo HS, Hoelz A. Characterization of the membrane-coating Nup84 complex: paradigm for the nuclear pore complex structure. Nucleus (Austin, Tex.). 1: 150-7. PMID 21326946 DOI: 10.4161/Nucl.1.2.11120  0.389
2010 Debler EW, Hsia K, Nagy V, Seo H, Hoelz A. Characterization of the membrane-coating Nup84 complex Nucleus. 1: 150-157. DOI: 10.4161/Nucl.11120  0.366
2009 Debler EW, Müller R, Hilvert D, Wilson IA. An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket. Proceedings of the National Academy of Sciences of the United States of America. 106: 18539-44. PMID 19846764 DOI: 10.1073/Pnas.0902700106  0.454
2009 Nagy V, Hsia KC, Debler EW, Kampmann M, Davenport AM, Blobel G, Hoelz A. Structure of a trimeric nucleoporin complex reveals alternate oligomerization states. Proceedings of the National Academy of Sciences of the United States of America. 106: 17693-8. PMID 19805193 DOI: 10.1073/Pnas.0909373106  0.681
2009 Seo HS, Ma Y, Debler EW, Wacker D, Kutik S, Blobel G, Hoelz A. Structural and functional analysis of Nup120 suggests ring formation of the Nup84 complex. Proceedings of the National Academy of Sciences of the United States of America. 106: 14281-6. PMID 19706512 DOI: 10.1073/Pnas.0907453106  0.574
2009 Debler EW, Blobel G, Hoelz A. Nuclear transport comes full circle. Nature Structural & Molecular Biology. 16: 457-9. PMID 19421156 DOI: 10.1038/Nsmb0509-457  0.522
2009 Napetschnig J, Kassube SA, Debler EW, Wong RW, Blobel G, Hoelz A. Structural and functional analysis of the interaction between the nucleoporin Nup214 and the DEAD-box helicase Ddx19. Proceedings of the National Academy of Sciences of the United States of America. 106: 3089-94. PMID 19208808 DOI: 10.1073/Pnas.0813267106  0.534
2008 Debler EW, Ma Y, Seo HS, Hsia KC, Noriega TR, Blobel G, Hoelz A. A fence-like coat for the nuclear pore membrane. Molecular Cell. 32: 815-26. PMID 19111661 DOI: 10.1016/J.Molcel.2008.12.001  0.488
2008 Debler EW, Müller R, Hilvert D, Wilson IA. Conformational isomerism can limit antibody catalysis. The Journal of Biological Chemistry. 283: 16554-60. PMID 18417480 DOI: 10.1074/Jbc.M710256200  0.474
2008 Debler EW, Kaufmann GF, Meijler MM, Heine A, Mee JM, Pljevaljcic G, Di Bilio AJ, Schultz PG, Millar DP, Janda KD, Wilson IA, Gray HB, Lerner RA. Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex. Science (New York, N.Y.). 319: 1232-5. PMID 18309081 DOI: 10.1126/Science.1153445  0.466
2007 Stoll R, Lee BM, Debler EW, Laity JH, Wilson IA, Dyson HJ, Wright PE. Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA. Journal of Molecular Biology. 372: 1227-45. PMID 17716689 DOI: 10.1016/J.Jmb.2007.07.017  0.507
2007 Debler EW, Kaufmann GF, Kirchdoerfer RN, Mee JM, Janda KD, Wilson IA. Crystal structures of a quorum-quenching antibody. Journal of Molecular Biology. 368: 1392-402. PMID 17400249 DOI: 10.1016/J.Jmb.2007.02.081  0.494
2007 Müller R, Debler EW, Steinmann M, Seebeck FP, Wilson IA, Hilvert D. Bifunctional catalysis of proton transfer at an antibody active site. Journal of the American Chemical Society. 129: 460-1. PMID 17226987 DOI: 10.1021/Ja066578B  0.476
2006 Tian F, Debler EW, Millar DP, Deniz AA, Wilson IA, Schultz PG. The effects of antibodies on stilbene excited-state energetics. Angewandte Chemie (International Ed. in English). 45: 7763-5. PMID 17089439 DOI: 10.1002/Anie.200602720  0.37
2006 Stauber DJ, Debler EW, Horton PA, Smith KA, Wilson IA. Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor. Proceedings of the National Academy of Sciences of the United States of America. 103: 2788-93. PMID 16477002 DOI: 10.1073/Pnas.0511161103  0.379
2005 Debler EW, Ito S, Seebeck FP, Heine A, Hilvert D, Wilson IA. Structural origins of efficient proton abstraction from carbon by a catalytic antibody. Proceedings of the National Academy of Sciences of the United States of America. 102: 4984-9. PMID 15788533 DOI: 10.1073/Pnas.0409207102  0.498
2005 Debler EW, Kaufmann GF, Di Bilio A, Gray HB, Lerner RA, Janda KD, Wilson IA. Structural basis for blue and purple fluorescence of antibody-stilbene complexes Acta Crystallographica Section a Foundations of Crystallography. 61: c229-c230. DOI: 10.1107/S0108767305090227  0.474
2004 Kelker MS, Debler EW, Wilson IA. Crystal structure of mouse triggering receptor expressed on myeloid cells 1 (TREM-1) at 1.76 A. Journal of Molecular Biology. 344: 1175-81. PMID 15561137 DOI: 10.1016/J.Jmb.2004.10.009  0.664
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