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Reina N. Fuji, Ph.D. - Publications

Affiliations: 
2005 Cornell University, Ithaca, NY, United States 
Area:
Signal Transduction Mechanisms
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5/39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Erickson JW, Antonyak MA, Fuji R, Cerione RA. Rho GTPases in cancer Ras Superfamily Small G Proteins: Biology and Mechanisms 1: General Features, Signaling. 421-438. DOI: 10.1007/978-3-7091-1806-1_18  0.361
2010 Wang JB, Erickson JW, Fuji R, Ramachandran S, Gao P, Dinavahi R, Wilson KF, Ambrosio AL, Dias SM, Dang CV, Cerione RA. Targeting mitochondrial glutaminase activity inhibits oncogenic transformation. Cancer Cell. 18: 207-19. PMID 20832749 DOI: 10.1016/J.Ccr.2010.08.009  0.502
2010 Wang JB, Erickson JW, Fuji R, Ramachandran S, Gao P, Dinavahi R, Wilson KF, Ambrosio ALB, Dias SMG, Dang CV, Cerione RA. Targeting mitochondrial glutaminase activity inhibits oncogenic transformation Cancer Cell. 18: 397. DOI: 10.1016/j.ccr.2010.10.011  0.433
2006 Wakshlag JJ, McNeill CJ, Antonyak MA, Boehm JE, Fuji R, Balkman CE, Zgola M, Cerione RA, Page RL. Expression and activity of transglutaminase II in spontaneous tumours of dogs and cats. Journal of Comparative Pathology. 134: 202-10. PMID 16615935 DOI: 10.1016/J.Jcpa.2005.11.001  0.438
2003 Lin Q, Fuji RN, Yang W, Cerione RA. RhoGDI is required for Cdc42-mediated cellular transformation. Current Biology : Cb. 13: 1469-79. PMID 12956948 DOI: 10.1016/S0960-9822(03)00613-4  0.482
Low-probability matches (unlikely to be authored by this person)
2013 Boswell CA, Mundo EE, Firestein R, Zhang C, Mao W, Gill H, Young C, Ljumanovic N, Stainton S, Ulufatu S, Fourie A, Kozak KR, Fuji R, Polakis P, Khawli LA, et al. An integrated approach to identify normal tissue expression of targets for antibody-drug conjugates: case study of TENB2. British Journal of Pharmacology. 168: 445-57. PMID 22889168 DOI: 10.1111/J.1476-5381.2012.02138.X  0.245
2004 White KS, Fuji RN, Valentine BA, Bildfell RJ. Equine congenital papilloma: pathological findings and results of papillomavirus immunohistochemistry in five cases. Veterinary Dermatology. 15: 240-4. PMID 15305931 DOI: 10.1111/J.1365-3164.2004.00395.X  0.224
2015 Fuji RN, Flagella M, Baca M, Baptista MA, Brodbeck J, Chan BK, Fiske BK, Honigberg L, Jubb AM, Katavolos P, Lee DW, Lewin-Koh SC, Lin T, Liu X, Liu S, et al. Effect of selective LRRK2 kinase inhibition on nonhuman primate lung. Science Translational Medicine. 7: 273ra15. PMID 25653221 DOI: 10.1126/Scitranslmed.Aaa3634  0.181
2014 Estrada AA, Chan BK, Baker-Glenn C, Beresford A, Burdick DJ, Chambers M, Chen H, Dominguez SL, Dotson J, Drummond J, Flagella M, Fuji R, Gill A, Halladay J, Harris SF, et al. Discovery of highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors. Journal of Medicinal Chemistry. 57: 921-36. PMID 24354345 DOI: 10.1021/Jm401654J  0.149
2010 Junutula JR, Flagella KM, Graham RA, Parsons KL, Ha E, Raab H, Bhakta S, Nguyen T, Dugger DL, Li G, Mai E, Lewis Phillips GD, Hiraragi H, Fuji RN, Tibbitts J, et al. Engineered thio-trastuzumab-DM1 conjugate with an improved therapeutic index to target human epidermal growth factor receptor 2-positive breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 4769-78. PMID 20805300 DOI: 10.1158/1078-0432.Ccr-10-0987  0.142
2012 Estrada AA, Liu X, Baker-Glenn C, Beresford A, Burdick DJ, Chambers M, Chan BK, Chen H, Ding X, DiPasquale AG, Dominguez SL, Dotson J, Drummond J, Flagella M, Flynn S, ... Fuji R, et al. Discovery of highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors. Journal of Medicinal Chemistry. 55: 9416-33. PMID 22985112 DOI: 10.1021/Jm301020Q  0.135
2005 Fuji RN, Patton KM, Steinbach TJ, Schulman FY, Bradley GA, Brown TT, Wilson EA, Summers BA. Feline systemic reactive angioendotheliomatosis: eight cases and literature review. Veterinary Pathology. 42: 608-17. PMID 16145207 DOI: 10.1354/Vp.42-5-608  0.135
2017 Patel S, Meilandt WJ, Erickson RI, Chen J, Deshmukh G, Estrada AA, Fuji RN, Gibbons P, Gustafson A, Harris SF, Imperio J, Liu W, Liu X, Liu Y, Lyssikatos JP, et al. Selective Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12) with Activity in a Model of Alzheimer's Disease. Journal of Medicinal Chemistry. PMID 28929759 DOI: 10.1021/Acs.Jmedchem.7B00843  0.126
2012 Polson AG, Fuji RN. The successes and limitations of preclinical studies in predicting the pharmacodynamics and safety of cell-surface-targeted biological agents in patients. British Journal of Pharmacology. 166: 1600-2. PMID 22364106 DOI: 10.1111/j.1476-5381.2012.01916.x  0.118
2020 Baptista MAS, Merchant K, Barrett T, Bhargava S, Bryce DK, Ellis JM, Estrada AA, Fell MJ, Fiske BK, Fuji RN, Galatsis P, Henry AG, Hill S, Hirst W, Houle C, et al. LRRK2 inhibitors induce reversible changes in nonhuman primate lungs without measurable pulmonary deficits. Science Translational Medicine. 12. PMID 32321864 DOI: 10.1126/Scitranslmed.Aav0820  0.112
2009 Zheng B, Fuji RN, Elkins K, Yu SF, Fuh FK, Chuh J, Tan C, Hongo JA, Raab H, Kozak KR, Williams M, McDorman E, Eaton D, Ebens A, Polson AG. In vivo effects of targeting CD79b with antibodies and antibody-drug conjugates. Molecular Cancer Therapeutics. 8: 2937-46. PMID 19808977 DOI: 10.1158/1535-7163.MCT-09-0369  0.108
2010 Polson AG, Williams M, Gray AM, Fuji RN, Poon KA, McBride J, Raab H, Januario T, Go M, Lau J, Yu SF, Du C, Fuh F, Tan C, Wu Y, et al. Anti-CD22-MCC-DM1: an antibody-drug conjugate with a stable linker for the treatment of non-Hodgkin's lymphoma. Leukemia. 24: 1566-73. PMID 20596033 DOI: 10.1038/leu.2010.141  0.102
2007 Xie D, Baudys J, Chan P, Deng R, Dere R, Ebens A, Fielder P, Fuh F, Fuji R, Gray A, Huang C, Jumbe S, Makeever K, Saad O, Stephan J, et al. Non-Clinical Pharmacology of Anti-CD22 Antibody Drug Conjugates. Blood. 110: 2363-2363. DOI: 10.1182/blood.V110.11.2363.2363  0.095
2009 Polson AG, Calemine-Fenaux J, Chan P, Chang W, Christensen E, Clark S, de Sauvage FJ, Eaton D, Elkins K, Elliott JM, Frantz G, Fuji RN, Gray A, Harden K, Ingle GS, et al. Antibody-drug conjugates for the treatment of non-Hodgkin's lymphoma: target and linker-drug selection. Cancer Research. 69: 2358-64. PMID 19258515 DOI: 10.1158/0008-5472.CAN-08-2250  0.095
2019 Meilandt WJ, Maloney JA, Imperio J, Lalehzadeh G, Earr T, Crowell S, Bainbridge TW, Lu Y, Ernst JA, Fuji RN, Atwal JK. Characterization of the selective in vitro and in vivo binding properties of crenezumab to oligomeric Aβ. Alzheimer's Research & Therapy. 11: 97. PMID 31787113 DOI: 10.1186/S13195-019-0553-5  0.088
2019 Butt M, Fuji R, Reichelt M, Sharma AK, Cramer S. Autophagy of Sensory Neurons in the Trigeminal and Dorsal Root Ganglia of Cynomolgus Monkeys (). Toxicologic Pathology. 192623319857053. PMID 31269872 DOI: 10.1177/0192623319857053  0.08
2021 Ayalon G, Lee SH, Adolfsson O, Foo-Atkins C, Atwal JK, Blendstrup M, Booler H, Bravo J, Brendza R, Brunstein F, Chan R, Chandra P, Couch JA, Datwani A, Demeule B, ... ... Fuji RN, et al. Antibody semorinemab reduces tau pathology in a transgenic mouse model and engages tau in patients with Alzheimer's disease. Science Translational Medicine. 13. PMID 33980574 DOI: 10.1126/scitranslmed.abb2639  0.078
2023 Shiffman S, Rios Piedra EA, Adedeji AO, Ruff CF, Andrews RN, Katavolos P, Liu E, Forster A, Brumm J, Fuji RN, Sullivan R. Analysis of cellularity in H&E-stained rat bone marrow tissue via deep learning. Journal of Pathology Informatics. 14: 100333. PMID 37743975 DOI: 10.1016/j.jpi.2023.100333  0.071
2022 Ramakrishnan V, Friedrich C, Witt C, Sheehan R, Pryor M, Atwal JK, Wildsmith K, Kudrycki K, Lee SH, Mazer N, Hofmann C, Fuji RN, Jin JY, Ramanujan S, Dolton M, et al. Quantitative Systems Pharmacology Model of the Amyloid Pathway in Alzheimer's Disease: Insights into the Therapeutic Mechanisms of Clinical Candidates. Cpt: Pharmacometrics & Systems Pharmacology. PMID 36281062 DOI: 10.1002/psp4.12876  0.061
2013 Couch JA, Yu YJ, Zhang Y, Tarrant JM, Fuji RN, Meilandt WJ, Solanoy H, Tong RK, Hoyte K, Luk W, Lu Y, Gadkar K, Prabhu S, Ordonia BA, Nguyen Q, et al. Addressing safety liabilities of TfR bispecific antibodies that cross the blood-brain barrier. Science Translational Medicine. 5: 183ra57, 1-12. PMID 23636093 DOI: 10.1126/Scitranslmed.3005338  0.057
2022 Zehnder P, Feng J, Fuji RN, Sullivan R, Hu F. Multiscale generative model using regularized skip-connections and perceptual loss for anomaly detection in toxicologic histopathology. Journal of Pathology Informatics. 13: 100102. PMID 36268071 DOI: 10.1016/j.jpi.2022.100102  0.053
2022 Sadekar SS, Bowen M, Cai H, Jamalian S, Rafidi H, Shatz-Binder W, Lafrance-Vanasse J, Chan P, Meilandt WJ, Oldendorp A, Sreedhara A, Daugherty A, Crowell S, Wildsmith KR, Atwal J, ... Fuji RN, et al. Translational approaches for brain delivery of biologics via cerebrospinal fluid. Clinical Pharmacology and Therapeutics. PMID 35064573 DOI: 10.1002/cpt.2531  0.051
2007 Xie D, Deng R, Baudys J, Chan P, Dere R, Ebens A, Fielder P, Fuji R, Gray A, Hung C, Iyer S, McKeever K, Kenrick M, Leach W, Polson A, et al. Pharmacokinetics of Anti-CD22 Antibody Conjugates with Uncleavable and Cleavable Linkers in Rats. Blood. 110: 2361-2361. DOI: 10.1182/blood.V110.11.2361.2361  0.05
2017 Bumbaca Yadav D, Maloney JA, Wildsmith KR, Fuji RN, Meilandt WJ, Solanoy H, Lu Y, Peng K, Wilson B, Chan P, Gadkar K, Kosky A, Goo M, Daugherty A, Couch JA, et al. Widespread brain distribution and activity following anti-BACE1 intracerebroventricular infusion in nonhuman primates. British Journal of Pharmacology. PMID 28859225 DOI: 10.1111/Bph.14021  0.045
2012 Shen BQ, Xu K, Liu L, Raab H, Bhakta S, Kenrick M, Parsons-Reponte KL, Tien J, Yu SF, Mai E, Li D, Tibbitts J, Baudys J, Saad OM, Scales SJ, ... ... Fuji RN, et al. Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates. Nature Biotechnology. 30: 184-9. PMID 22267010 DOI: 10.1038/Nbt.2108  0.045
2018 Salloway S, Honigberg LA, Cho W, Ward M, Friesenhahn M, Brunstein F, Quartino A, Clayton D, Mortensen D, Bittner T, Ho C, Rabe C, Schauer SP, Wildsmith KR, Fuji RN, et al. Amyloid positron emission tomography and cerebrospinal fluid results from a crenezumab anti-amyloid-beta antibody double-blind, placebo-controlled, randomized phase II study in mild-to-moderate Alzheimer's disease (BLAZE). Alzheimer's Research & Therapy. 10: 96. PMID 30231896 DOI: 10.1186/S13195-018-0424-5  0.041
2020 Ferl GZ, Fuji RN, Atwal JK, Sun T, Ramanujan S, Quartino AL. Mechanistic Modeling of Soluble Aβ Dynamics and Target Engagement in the Brain by Anti-Aβ mAbs in Alzheimer's Disease. Current Alzheimer Research. PMID 32116192 DOI: 10.2174/1567205017666200302122307  0.04
2022 Teng E, Manser PT, Pickthorn K, Brunstein F, Blendstrup M, Sanabria Bohorquez S, Wildsmith KR, Toth B, Dolton M, Ramakrishnan V, Bobbala A, Sikkes SAM, Ward M, Fuji RN, Kerchner GA. Safety and Efficacy of Semorinemab in Individuals With Prodromal to Mild Alzheimer Disease: A Randomized Clinical Trial. Jama Neurology. PMID 35696185 DOI: 10.1001/jamaneurol.2022.1375  0.039
2022 Ge XY, Funk J, Albrecht T, Birkhimer M, Gilsdorf M, Hayes M, Hu F, Maliver P, McCreary M, Nguyen T, Romero-Palomo F, Seger S, Fuji RN, Schumacher V, Sullivan R. Toxicologic Pathology Forum: A Roadmap for Building State-of-the-Art Digital Image Data Resources for Toxicologic Pathology in the Pharmaceutical Industry. Toxicologic Pathology. 1926233221132747. PMID 36341579 DOI: 10.1177/01926233221132747  0.037
2018 Shiffman S, Basak S, Kozlowski C, Fuji RN. An automated mapping method for Nissl-stained mouse brain histologic sections. Journal of Neuroscience Methods. PMID 30096343 DOI: 10.1016/j.jneumeth.2018.08.005  0.036
1998 Pehrson JR, Fuji RN. Evolutionary conservation of histone macroH2A subtypes and domains. Nucleic Acids Research. 26: 2837-42. PMID 9611225 DOI: 10.1093/nar/26.12.2837  0.035
1999 Scott DW, Fuji RN. Equine "axillary nodular necrosis:"What is it? Equine Pratice. 21: 14-17.  0.026
2024 Chu ML, Ge XM, Eastham J, Nguyen T, Fuji RN, Sullivan R, Ruderman D. Assessment of Color Reproducibility and Mitigation of Color Variation in Whole Slide Image Scanners for Toxicologic Pathology. Toxicologic Pathology. 1926233231224468. PMID 38288712 DOI: 10.1177/01926233231224468  0.018
2018 Cummings JL, Cohen S, van Dyck CH, Brody M, Curtis C, Cho W, Ward M, Friesenhahn M, Rabe C, Brunstein F, Quartino A, Honigberg LA, Fuji RN, Clayton D, Mortensen D, et al. ABBY: A phase 2 randomized trial of crenezumab in mild to moderate Alzheimer disease. Neurology. PMID 29695589 DOI: 10.1212/WNL.0000000000005550  0.01
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