Scott B. Ficarro, Ph.D. - Publications

Affiliations: 
2002 University of Virginia, Charlottesville, VA 
Area:
Analytical Biochemistry

101 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Park E, Rawson S, Li K, Kim BW, Ficarro SB, Pino GG, Sharif H, Marto JA, Jeon H, Eck MJ. Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes. Nature. PMID 31581174 DOI: 10.1038/s41586-019-1660-y  0.72
2019 Twomey EC, Ji Z, Wales TE, Bodnar NO, Ficarro SB, Marto JA, Engen JR, Rapoport TA. Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding. Science (New York, N.Y.). PMID 31249135 DOI: 10.1126/science.aax1033  0.72
2019 Ferguson FM, Doctor ZM, Ficarro SB, Marto JA, Kim ND, Sim T, Gray NS. Synthesis and structure activity relationships of a series of 4-amino-1H-pyrazoles as covalent inhibitors of CDK14. Bioorganic & Medicinal Chemistry Letters. PMID 31175010 DOI: 10.1016/j.bmcl.2019.05.024  0.72
2019 Rao S, Gurbani D, Du G, Everley RA, Browne CM, Chaikuad A, Li T, Schröder M, Gondi S, Ficarro SB, Sim T, Kim ND, Berberich MJ, Knapp S, Marto JA, et al. Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome. Cell Chemical Biology. PMID 30982749 DOI: 10.1016/j.chembiol.2019.02.021  0.72
2019 Ferguson FM, Doctor ZM, Ficarro SB, Browne CM, Marto JA, Johnson JL, Yaron TM, Cantley LC, Kim ND, Sim T, Berberich MJ, Kalocsay M, Sorger PK, Gray NS. Discovery of Covalent CDK14 Inhibitors with Pan-TAIRE Family Specificity. Cell Chemical Biology. PMID 30930164 DOI: 10.1016/j.chembiol.2019.02.015  0.72
2019 Olson CM, Liang Y, Leggett A, Park WD, Li L, Mills CE, Elsarrag SZ, Ficarro SB, Zhang T, Düster R, Geyer M, Sim T, Marto JA, Sorger PK, Westover KD, et al. Development of a Selective CDK7 Covalent Inhibitor Reveals Predominant Cell-Cycle Phenotype. Cell Chemical Biology. PMID 30905681 DOI: 10.1016/j.chembiol.2019.02.012  0.72
2019 Joo YJ, Ficarro SB, Chun Y, Marto JA, Buratowski S. In vitro analysis of RNA polymerase II elongation complex dynamics. Genes & Development. PMID 30846429 DOI: 10.1101/gad.324202.119  0.72
2019 Joo YJ, Ficarro SB, Marto JA, Buratowski S. In vitro assembly and proteomic analysis of RNA polymerase II complexes. Methods (San Diego, Calif.). PMID 30844430 DOI: 10.1016/j.ymeth.2019.03.001  0.72
2018 Browne CM, Jiang B, Ficarro SB, Doctor ZM, Johnson JL, Card JD, Sivakumaren SC, Alexander WM, Yaron T, Murphy CJ, Kwiatkowski NP, Zhang T, Cantley LC, Gray NS, Marto JA. A Chemoproteomic Strategy for Direct and Proteome-wide Covalent Inhibitor Target-site Identification. Journal of the American Chemical Society. PMID 30518210 DOI: 10.1021/jacs.8b07911  0.72
2018 Chu N, Salguero AL, Liu AZ, Chen Z, Dempsey DR, Ficarro SB, Alexander WM, Marto JA, Li Y, Amzel LM, Gabelli SB, Cole PA. Akt Kinase Activation Mechanisms Revealed Using Protein Semisynthesis. Cell. PMID 30078705 DOI: 10.1016/j.cell.2018.07.003  0.72
2018 de Wispelaere M, Lian W, Potisopon S, Li PC, Jang J, Ficarro SB, Clark MJ, Zhu X, Kaplan JB, Pitts JD, Wales TE, Wang J, Engen JR, Marto JA, Gray NS, et al. Inhibition of Flaviviruses by Targeting a Conserved Pocket on the Viral Envelope Protein. Cell Chemical Biology. PMID 29937406 DOI: 10.1016/j.chembiol.2018.05.011  0.72
2018 Hatcher JM, Wu G, Zeng C, Zhu J, Meng F, Patel S, Wang W, Ficarro SB, Leggett AL, Powell CE, Marto JA, Zhang K, Ki Ngo JC, Fu XD, Zhang T, et al. SRPKIN-1: A Covalent SRPK1/2 Inhibitor that Potently Converts VEGF from Pro-angiogenic to Anti-angiogenic Isoform. Cell Chemical Biology. PMID 29478907 DOI: 10.1016/j.chembiol.2018.01.013  0.72
2017 Gao Y, Zhang T, Terai H, Ficarro SB, Kwiatkowski N, Hao MF, Sharma B, Christensen CL, Chipumuro E, Wong KK, Marto JA, Hammerman PS, Gray NS, George RE. Overcoming Resistance to the THZ Series of Covalent Transcriptional CDK Inhibitors. Cell Chemical Biology. PMID 29276047 DOI: 10.1016/j.chembiol.2017.11.007  0.72
2017 Soltis AR, Kennedy NJ, Xin X, Zhou F, Ficarro SB, Yap YS, Matthews BJ, Lauffenburger DA, White FM, Marto JA, Davis RJ, Fraenkel E. Hepatic Dysfunction Caused by Consumption of a High-Fat Diet. Cell Reports. 21: 3317-3328. PMID 29241556 DOI: 10.1016/j.celrep.2017.11.059  0.72
2017 Joo YJ, Ficarro SB, Soares LM, Chun Y, Marto JA, Buratowski S. Downstream promoter interactions of TFIID TAFs facilitate transcription reinitiation. Genes & Development. 31: 2162-2174. PMID 29203645 DOI: 10.1101/gad.306324.117  0.72
2017 Cato L, Neeb A, Sharp A, Buzón V, Ficarro SB, Yang L, Muhle-Goll C, Kuznik NC, Riisnaes R, Nava Rodrigues D, Armant O, Gourain V, Adelmant G, Ntim EA, Westerling T, et al. Development of Bag-1L as a therapeutic target in androgen receptor-dependent prostate cancer. Elife. 6. PMID 28826504 DOI: 10.7554/eLife.27159  0.72
2017 Zeng M, Lu J, Li L, Feru F, Quan C, Gero TW, Ficarro SB, Xiong Y, Ambrogio C, Paranal RM, Catalano M, Shao J, Wong KK, Marto JA, Fischer ES, et al. Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C. Cell Chemical Biology. PMID 28781124 DOI: 10.1016/j.chembiol.2017.06.017  0.72
2017 Ficarro SB, Alexander WM, Marto JA. mzStudio: A Dynamic Digital Canvas for User-Driven Interrogation of Mass Spectrometry Data. Proteomes. 5. PMID 28763045 DOI: 10.3390/proteomes5030020  0.72
2017 Alexander WM, Ficarro SB, Adelmant G, Marto JA. multiplierz v2.0: a Python-based ecosystem for shared access and analysis of native mass spectrometry data. Proteomics. PMID 28686798 DOI: 10.1002/pmic.201700091  0.72
2017 Zhou J, Tien AC, Alberta JA, Ficarro SB, Griveau A, Sun Y, Deshpande JS, Card JD, Morgan-Smith M, Michowski W, Hashizume R, James CD, Ligon KL, Snider WD, Sicinski P, et al. A Sequentially Priming Phosphorylation Cascade Activates the Gliomagenic Transcription Factor Olig2. Cell Reports. 18: 3167-3177. PMID 28355568 DOI: 10.1016/j.celrep.2017.03.003  0.72
2017 Tavera-Mendoza LE, Westerling T, Libby E, Marusyk A, Cato L, Cassani R, Cameron LA, Ficarro SB, Marto JA, Klawitter J, Brown M. Vitamin D receptor regulates autophagy in the normal mammary gland and in luminal breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 28242709 DOI: 10.1073/pnas.1615015114  0.72
2017 Chen H, Coseno M, Ficarro SB, Mansueto MS, Komazin-Meredith G, Boissel S, Filman DJ, Marto JA, Hogle JM, Coen DM. A Small Covalent Allosteric Inhibitor of Human Cytomegalovirus DNA Polymerase Subunit Interactions. Acs Infectious Diseases. 3: 112-118. PMID 28183184 DOI: 10.1021/acsinfecdis.6b00079  0.72
2016 Ficarro SB, Browne CM, Card JD, Alexander WM, Zhang T, Park E, McNally R, Dhe-Paganon S, Seo HS, Lamberto I, Eck MJ, Buhrlage SJ, Gray NS, Marto JA. Leveraging Gas-Phase Fragmentation Pathways for Improved Identification and Selective Detection of Targets Modified by Covalent Probes. Analytical Chemistry. 88: 12248-12254. PMID 28193034 DOI: 10.1021/acs.analchem.6b03394  0.72
2016 Durzynska I, Xu X, Adelmant G, Ficarro SB, Marto JA, Sliz P, Uljon S, Blacklow SC. STK40 Is a Pseudokinase that Binds the E3 Ubiquitin Ligase COP1. Structure (London, England : 1993). PMID 28089446 DOI: 10.1016/j.str.2016.12.008  0.72
2016 Tan L, Gurbani D, Weisberg EL, Hunter JC, Li L, Jones DS, Ficarro SB, Mowafy S, Tam CP, Rao S, Du G, Griffin JD, Sorger PK, Marto JA, Westover KD, et al. Structure-guided development of covalent TAK1 inhibitors. Bioorganic & Medicinal Chemistry. PMID 28011204 DOI: 10.1016/j.bmc.2016.11.035  0.72
2016 Harshbarger W, Gondi S, Ficarro SB, Hunter J, Udayakumar D, Gurbani D, Singer W, Liu Y, Li L, Marto JA, Westover KD. Structural and Biochemical Analyses Reveal the Mechanism of Glutathione S-Transferase Pi 1 Inhibition by the Anti-cancer Compound Piperlongumine. The Journal of Biological Chemistry. PMID 27872191 DOI: 10.1074/jbc.M116.750299  0.72
2016 Norberg E, Lako A, Chen PH, Stanley IA, Zhou F, Ficarro SB, Chapuy B, Chen L, Rodig S, Shin D, Choi DW, Lee S, Shipp MA, Marto JA, Danial NN. Differential contribution of the mitochondrial translation pathway to the survival of diffuse large B-cell lymphoma subsets. Cell Death and Differentiation. PMID 27768122 DOI: 10.1038/cdd.2016.116  0.72
2016 Zhang T, Kwiatkowski N, Olson CM, Dixon-Clarke SE, Abraham BJ, Greifenberg AK, Ficarro SB, Elkins JM, Liang Y, Hannett NM, Manz T, Hao M, Bartkowiak B, Greenleaf AL, Marto JA, et al. Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors. Nature Chemical Biology. PMID 27571479 DOI: 10.1038/nchembio.2166  0.72
2016 Wang LD, Ficarro SB, Hutchinson JN, Csepanyi-Komi R, Nguyen PT, Wisniewski E, Sullivan J, Hofmann O, Ligeti E, Marto JA, Wagers AJ. Phosphoproteomic profiling of mouse primary hematopoietic stem and progenitor cells reveals new regulators of HSPC mobilization. Blood. PMID 27365422 DOI: 10.1182/blood-2016-05-711424  0.72
2016 Zhang J, Ratanasirintrawoot S, Chandrasekaran S, Wu Z, Ficarro SB, Yu C, Ross CA, Cacchiarelli D, Xia Q, Seligson M, Shinoda G, Xie W, Cahan P, Wang L, Ng SC, et al. LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency. Cell Stem Cell. PMID 27320042 DOI: 10.1016/j.stem.2016.05.009  0.72
2016 Suh H, Ficarro SB, Kang UB, Chun Y, Marto JA, Buratowski S. Direct Analysis of Phosphorylation Sites on the Rpb1 C-Terminal Domain of RNA Polymerase II. Molecular Cell. 61: 297-304. PMID 26799764 DOI: 10.1016/j.molcel.2015.12.021  0.72
2015 Park E, Kim N, Ficarro SB, Zhang Y, Lee BI, Cho A, Kim K, Park AK, Park WY, Murray B, Meyerson M, Beroukhim R, Marto JA, Cho J, Eck MJ. Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6. Nature Structural & Molecular Biology. 22: 703-11. PMID 26280531 DOI: 10.1038/nsmb.3074  0.72
2015 Tan L, Akahane K, McNally R, Reyskens KM, Ficarro SB, Liu S, Herter-Sprie GS, Koyama S, Pattison MJ, Labella KM, Johannessen L, Akbay EA, Wong KK, Frank DA, Marto JA, et al. Development of Selective Covalent JAK3 Inhibitors. Journal of Medicinal Chemistry. PMID 26258521 DOI: 10.1021/acs.jmedchem.5b00710  0.72
2015 Lim SM, Xie T, Westover KD, Ficarro SB, Tae HS, Gurbani D, Sim T, Marto JA, Jänne PA, Crews CM, Gray NS. Development of small molecules targeting the pseudokinase Her3. Bioorganic & Medicinal Chemistry Letters. 25: 3382-9. PMID 26094118 DOI: 10.1016/j.bmcl.2015.04.103  0.72
2015 Zhu D, Wang Z, Zhao JJ, Calimeri T, Meng J, Hideshima T, Fulciniti M, Kang Y, Ficarro SB, Tai YT, Hunter Z, McMilin D, Tong H, Mitsiades CS, Wu CJ, et al. The Cyclophilin A-CD147 complex promotes the proliferation and homing of multiple myeloma cells. Nature Medicine. 21: 572-80. PMID 26005854 DOI: 10.1038/nm.3867  0.72
2015 Labidi-Galy SI, Clauss A, Ng V, Duraisamy S, Elias KM, Piao HY, Bilal E, Davidowitz RA, Lu Y, Badalian-Very G, Györffy B, Kang UB, Ficarro S, Ganesan S, Mills GB, et al. Elafin drives poor outcome in high-grade serous ovarian cancers and basal-like breast tumors. Oncogene. 34: 373-83. PMID 24469047 DOI: 10.1038/onc.2013.562  0.72
2015 Park E, Kim N, Ficarro SB, Zhang Y, Lee BI, Cho A, Kim K, Park AKJ, Park WY, Murray B, Meyerson M, Beroukhim R, Marto JA, Cho J, Eck MJ. Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6 Nature Structural and Molecular Biology. DOI: 10.1038/nsmb.3074  0.72
2014 Xie T, Lim SM, Westover KD, Dodge ME, Ercan D, Ficarro SB, Udayakumar D, Gurbani D, Tae HS, Riddle SM, Sim T, Marto JA, Jänne PA, Crews CM, Gray NS. Pharmacological targeting of the pseudokinase Her3. Nature Chemical Biology. 10: 1006-12. PMID 25326665 DOI: 10.1038/nchembio.1658  0.72
2014 Hu Y, Petit SA, Ficarro SB, Toomire KJ, Xie A, Lim E, Cao SA, Park E, Eck MJ, Scully R, Brown M, Marto JA, Livingston DM. PARP1-driven poly-ADP-ribosylation regulates BRCA1 function in homologous recombination-mediated DNA repair. Cancer Discovery. 4: 1430-47. PMID 25252691 DOI: 10.1158/2159-8290.CD-13-0891  0.72
2014 Gridling M, Ficarro SB, Breitwieser FP, Song L, Parapatics K, Colinge J, Haura EB, Marto JA, Superti-Furga G, Bennett KL, Rix U. Identification of kinase inhibitor targets in the lung cancer microenvironment by chemical and phosphoproteomics. Molecular Cancer Therapeutics. 13: 2751-62. PMID 25189542 DOI: 10.1158/1535-7163.MCT-14-0152  0.72
2014 Kwiatkowski N, Zhang T, Rahl PB, Abraham BJ, Reddy J, Ficarro SB, Dastur A, Amzallag A, Ramaswamy S, Tesar B, Jenkins CE, Hannett NM, McMillin D, Sanda T, Sim T, et al. Targeting transcription regulation in cancer with a covalent CDK7 inhibitor. Nature. 511: 616-20. PMID 25043025 DOI: 10.1038/nature13393  0.72
2014 Hunter JC, Gurbani D, Ficarro SB, Carrasco MA, Lim SM, Choi HG, Xie T, Marto JA, Chen Z, Gray NS, Westover KD. In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C. Proceedings of the National Academy of Sciences of the United States of America. 111: 8895-900. PMID 24889603 DOI: 10.1073/pnas.1404639111  0.72
2014 Lu Y, Loh YH, Li H, Cesana M, Ficarro SB, Parikh JR, Salomonis N, Toh CX, Andreadis ST, Luckey CJ, Collins JJ, Daley GQ, Marto JA. Alternative splicing of MBD2 supports self-renewal in human pluripotent stem cells. Cell Stem Cell. 15: 92-101. PMID 24813856 DOI: 10.1016/j.stem.2014.04.002  0.72
2014 Ficarro SB, Biagi JM, Wang J, Scotcher J, Koleva RI, Card JD, Adelmant G, He H, Askenazi M, Marshall AG, Young NL, Gray NS, Marto JA. Protected amine labels: a versatile molecular scaffold for multiplexed nominal mass and sub-Da isotopologue quantitative proteomic reagents. Journal of the American Society For Mass Spectrometry. 25: 636-50. PMID 24496597 DOI: 10.1007/s13361-013-0811-x  0.72
2014 Lim SM, Westover KD, Ficarro SB, Harrison RA, Choi HG, Pacold ME, Carrasco M, Hunter J, Kim ND, Xie T, Sim T, Jänne PA, Meyerson M, Marto JA, Engen JR, et al. Therapeutic targeting of oncogenic K-Ras by a covalent catalytic site inhibitor. Angewandte Chemie (International Ed. in English). 53: 199-204. PMID 24259466 DOI: 10.1002/anie.201307387  0.72
2013 Toms AV, Deshpande A, McNally R, Jeong Y, Rogers JM, Kim CU, Gruner SM, Ficarro SB, Marto JA, Sattler M, Griffin JD, Eck MJ. Structure of a pseudokinase-domain switch that controls oncogenic activation of Jak kinases. Nature Structural & Molecular Biology. 20: 1221-3. PMID 24013208 DOI: 10.1038/nsmb.2673  0.72
2013 Zhou F, Lu Y, Ficarro SB, Adelmant G, Jiang W, Luckey CJ, Marto JA. Genome-scale proteome quantification by DEEP SEQ mass spectrometry. Nature Communications. 4: 2171. PMID 23863870 DOI: 10.1038/ncomms3171  0.72
2013 Andrawes MB, Xu X, Liu H, Ficarro SB, Marto JA, Aster JC, Blacklow SC. Intrinsic selectivity of Notch 1 for Delta-like 4 over Delta-like 1. The Journal of Biological Chemistry. 288: 25477-89. PMID 23839946 DOI: 10.1074/jbc.M113.454850  0.72
2013 Webber JT, Askenazi M, Ficarro SB, Iglehart MA, Marto JA. Library dependent LC-MS/MS acquisition via mzAPI/Live. Proteomics. 13: 1412-6. PMID 23457059 DOI: 10.1002/pmic.201200583  0.72
2013 Tu D, Zhu Z, Zhou AY, Yun CH, Lee KE, Toms AV, Li Y, Dunn GP, Chan E, Thai T, Yang S, Ficarro SB, Marto JA, Jeon H, Hahn WC, et al. Structure and ubiquitination-dependent activation of TANK-binding kinase 1. Cell Reports. 3: 747-58. PMID 23453972 DOI: 10.1016/j.celrep.2013.01.033  0.72
2012 Caro P, Kishan AU, Norberg E, Stanley IA, Chapuy B, Ficarro SB, Polak K, Tondera D, Gounarides J, Yin H, Zhou F, Green MR, Chen L, Monti S, Marto JA, et al. Metabolic signatures uncover distinct targets in molecular subsets of diffuse large B cell lymphoma. Cancer Cell. 22: 547-60. PMID 23079663 DOI: 10.1016/j.ccr.2012.08.014  0.72
2012 Sikorski TW, Joo YJ, Ficarro SB, Askenazi M, Buratowski S, Marto JA. Proteomic analysis demonstrates activator- and chromatin-specific recruitment to promoters. The Journal of Biological Chemistry. 287: 35397-408. PMID 22902623 DOI: 10.1074/jbc.M112.391581  0.72
2012 Rozenblatt-Rosen O, Deo RC, Padi M, Adelmant G, Calderwood MA, Rolland T, Grace M, Dricot A, Askenazi M, Tavares M, Pevzner SJ, Abderazzaq F, Byrdsong D, Carvunis AR, Chen AA, ... ... Ficarro SB, et al. Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins. Nature. 487: 491-5. PMID 22810586 DOI: 10.1038/nature11288  0.72
2012 Zhou F, Lu Y, Ficarro SB, Webber JT, Marto JA. Nanoflow low pressure high peak capacity single dimension LC-MS/MS platform for high-throughput, in-depth analysis of mammalian proteomes. Analytical Chemistry. 84: 5133-9. PMID 22519751 DOI: 10.1021/ac2031404  0.72
2012 Koleva RI, Ficarro SB, Radomska HS, Carrasco-Alfonso MJ, Alberta JA, Webber JT, Luckey CJ, Marcucci G, Tenen DG, Marto JA. C/EBPα and DEK coordinately regulate myeloid differentiation. Blood. 119: 4878-88. PMID 22474248 DOI: 10.1182/blood-2011-10-383083  0.72
2012 Zhang T, Inesta-Vaquera F, Niepel M, Zhang J, Ficarro SB, Machleidt T, Xie T, Marto JA, Kim N, Sim T, Laughlin JD, Park H, LoGrasso PV, Patricelli M, Nomanbhoy TK, et al. Discovery of potent and selective covalent inhibitors of JNK. Chemistry & Biology. 19: 140-54. PMID 22284361 DOI: 10.1016/j.chembiol.2011.11.010  0.72
2012 Cardoza JD, Parikh JR, Ficarro SB, Marto JA. Mass spectrometry-based proteomics: qualitative identification to activity-based protein profiling. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. 4: 141-62. PMID 22231900 DOI: 10.1002/wsbm.166  0.72
2011 Sikorski TW, Ficarro SB, Holik J, Kim T, Rando OJ, Marto JA, Buratowski S. Sub1 and RPA associate with RNA polymerase II at different stages of transcription. Molecular Cell. 44: 397-409. PMID 22055186 DOI: 10.1016/j.molcel.2011.09.013  0.72
2011 Zhou F, Sikorski TW, Ficarro SB, Webber JT, Marto JA. Online nanoflow reversed phase-strong anion exchange-reversed phase liquid chromatography-tandem mass spectrometry platform for efficient and in-depth proteome sequence analysis of complex organisms. Analytical Chemistry. 83: 6996-7005. PMID 21851055 DOI: 10.1021/ac200639v  0.72
2011 Ficarro SB, Zhang Y, Carrasco-Alfonso MJ, Garg B, Adelmant G, Webber JT, Luckey CJ, Marto JA. Online nanoflow multidimensional fractionation for high efficiency phosphopeptide analysis. Molecular & Cellular Proteomics : McP. 10: O111.011064. PMID 21788404 DOI: 10.1074/mcp.O111.011064  0.72
2011 Tu D, Li Y, Song HK, Toms AV, Gould CJ, Ficarro SB, Marto JA, Goode BL, Eck MJ. Crystal structure of a coiled-coil domain from human ROCK I. Plos One. 6: e18080. PMID 21445309 DOI: 10.1371/journal.pone.0018080  0.72
2010 Gordon V, Bhadel S, Wunderlich W, Zhang J, Ficarro SB, Mollah SA, Shabanowitz J, Hunt DF, Xenarios I, Hahn WC, Conaway M, Carey MF, Gioeli D. CDK9 regulates AR promoter selectivity and cell growth through serine 81 phosphorylation. Molecular Endocrinology (Baltimore, Md.). 24: 2267-80. PMID 20980437 DOI: 10.1210/me.2010-0238  0.72
2010 Zhou F, Cardoza JD, Ficarro SB, Adelmant GO, Lazaro JB, Marto JA. Online nanoflow RP-RP-MS reveals dynamics of multicomponent Ku complex in response to DNA damage. Journal of Proteome Research. 9: 6242-55. PMID 20873769 DOI: 10.1021/pr1004696  0.72
2010 Zhou W, Hur W, McDermott U, Dutt A, Xian W, Ficarro SB, Zhang J, Sharma SV, Brugge J, Meyerson M, Settleman J, Gray NS. A structure-guided approach to creating covalent FGFR inhibitors. Chemistry & Biology. 17: 285-95. PMID 20338520 DOI: 10.1016/j.chembiol.2010.02.007  0.72
2009 Parikh JR, Askenazi M, Ficarro SB, Cashorali T, Webber JT, Blank NC, Zhang Y, Marto JA. multiplierz: an extensible API based desktop environment for proteomics data analysis. Bmc Bioinformatics. 10: 364. PMID 19874609 DOI: 10.1186/1471-2105-10-364  0.72
2009 Brill LM, Xiong W, Lee KB, Ficarro SB, Crain A, Xu Y, Terskikh A, Snyder EY, Ding S. Phosphoproteomic analysis of human embryonic stem cells. Cell Stem Cell. 5: 204-13. PMID 19664994 DOI: 10.1016/j.stem.2009.06.002  0.72
2009 Murrey HE, Ficarro SB, Krishnamurthy C, Domino SE, Peters EC, Hsieh-Wilson LC. Identification of the plasticity-relevant fucose-alpha(1-2)-galactose proteome from the mouse olfactory bulb. Biochemistry. 48: 7261-70. PMID 19527073 DOI: 10.1021/bi900640x  0.72
2009 Ficarro SB, Adelmant G, Tomar MN, Zhang Y, Cheng VJ, Marto JA. Magnetic bead processor for rapid evaluation and optimization of parameters for phosphopeptide enrichment. Analytical Chemistry. 81: 4566-75. PMID 19408940 DOI: 10.1021/ac9004452  0.72
2009 Zhang Y, Ficarro SB, Li S, Marto JA. Optimized Orbitrap HCD for quantitative analysis of phosphopeptides. Journal of the American Society For Mass Spectrometry. 20: 1425-34. PMID 19403316 DOI: 10.1016/j.jasms.2009.03.019  0.72
2009 Ficarro SB, Zhang Y, Lu Y, Moghimi AR, Askenazi M, Hyatt E, Smith ED, Boyer L, Schlaeger TM, Luckey CJ, Marto JA. Improved electrospray ionization efficiency compensates for diminished chromatographic resolution and enables proteomics analysis of tyrosine signaling in embryonic stem cells. Analytical Chemistry. 81: 3440-7. PMID 19331382 DOI: 10.1021/ac802720e  0.72
2008 Ortega-Gutiérrez S, Leung D, Ficarro S, Peters EC, Cravatt BF. Targeted disruption of the PME-1 gene causes loss of demethylated PP2A and perinatal lethality in mice. Plos One. 3: e2486. PMID 18596935 DOI: 10.1371/journal.pone.0002486  0.72
2008 Ficarro SB, Parikh JR, Blank NC, Marto JA. Niobium(V) oxide (Nb2O5): application to phosphoproteomics. Analytical Chemistry. 80: 4606-13. PMID 18491922 DOI: 10.1021/ac800564h  0.72
2008 Xu Q, Kozbial P, McMullan D, Krishna SS, Brittain SM, Ficarro SB, DiDonato M, Miller MD, Abdubek P, Axelrod HL, Chiu HJ, Clayton T, Duan L, Elsliger MA, Feuerhelm J, et al. Crystal structure of an ADP-ribosylated protein with a cytidine deaminase-like fold, but unknown function (TM1506), from Thermotoga maritima at 2.70 A resolution. Proteins. 71: 1546-52. PMID 18275082 DOI: 10.1002/prot.21992  0.72
2007 Pimienta G, Ficarro SB, Gutierrez GJ, Bhoumik A, Peters EC, Ronai Z, Pascual J. Autophosphorylation properties of inactive and active JNK2. Cell Cycle (Georgetown, Tex.). 6: 1762-71. PMID 17637567  0.72
2007 Khidekel N, Ficarro SB, Clark PM, Bryan MC, Swaney DL, Rexach JE, Sun YE, Coon JJ, Peters EC, Hsieh-Wilson LC. Probing the dynamics of O-GlcNAc glycosylation in the brain using quantitative proteomics. Nature Chemical Biology. 3: 339-48. PMID 17496889 DOI: 10.1038/nchembio881  0.72
2007 Lin CH, Platt MD, Ficarro SB, Hoofnagle MH, Shabanowitz J, Comai L, Hunt DF, Owens GK. Mass spectrometric identification of phosphorylation sites of rRNA transcription factor upstream binding factor. American Journal of Physiology. Cell Physiology. 292: C1617-24. PMID 17182730 DOI: 10.1152/ajpcell.00176.2006  0.72
2006 Mukherji M, Brill LM, Ficarro SB, Hampton GM, Schultz PG. A phosphoproteomic analysis of the ErbB2 receptor tyrosine kinase signaling pathways. Biochemistry. 45: 15529-40. PMID 17176074 DOI: 10.1021/bi060971c  0.72
2006 Tsuji T, Ficarro SB, Jiang W. Essential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cells. Molecular Biology of the Cell. 17: 4459-72. PMID 16899510 DOI: 10.1091/mbc.E06-03-0241  0.72
2005 Brittain SM, Ficarro SB, Brock A, Peters EC. Enrichment and analysis of peptide subsets using fluorous affinity tags and mass spectrometry. Nature Biotechnology. 23: 463-8. PMID 15768030 DOI: 10.1038/nbt1076  0.72
2005 Angenstein F, Evans AM, Ling SC, Settlage RE, Ficarro S, Carrero-Martinez FA, Shabanowitz J, Hunt DF, Greenough WT. Proteomic characterization of messenger ribonucleoprotein complexes bound to nontranslated or translated poly(A) mRNAs in the rat cerebral cortex. The Journal of Biological Chemistry. 280: 6496-503. PMID 15596439 DOI: 10.1074/jbc.M412742200  0.72
2005 Ficarro SB, Salomon AR, Brill LM, Mason DE, Stettler-Gill M, Brock A, Peters EC. Automated immobilized metal affinity chromatography/nano-liquid chromatography/electrospray ionization mass spectrometry platform for profiling protein phosphorylation sites. Rapid Communications in Mass Spectrometry : Rcm. 19: 57-71. PMID 15570572 DOI: 10.1002/rcm.1746  0.72
2005 Lee I, Salomon AR, Ficarro S, Mathes I, Lottspeich F, Grossman LI, Hüttemann M. cAMP-dependent tyrosine phosphorylation of subunit I inhibits cytochrome c oxidase activity. The Journal of Biological Chemistry. 280: 6094-100. PMID 15557277 DOI: 10.1074/jbc.M411335200  0.72
2004 Khidekel N, Ficarro SB, Peters EC, Hsieh-Wilson LC. Exploring the O-GlcNAc proteome: direct identification of O-GlcNAc-modified proteins from the brain. Proceedings of the National Academy of Sciences of the United States of America. 101: 13132-7. PMID 15340146 DOI: 10.1073/pnas.0403471101  0.72
2004 Tai HC, Khidekel N, Ficarro SB, Peters EC, Hsieh-Wilson LC. Parallel identification of O-GlcNAc-modified proteins from cell lysates. Journal of the American Chemical Society. 126: 10500-1. PMID 15327282 DOI: 10.1021/ja047872b  0.72
2004 Brill LM, Salomon AR, Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC. Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. Analytical Chemistry. 76: 2763-72. PMID 15144186 DOI: 10.1021/ac035352d  0.72
2004 Peters EC, Brock A, Ficarro SB. Exploring the phosphoproteome with mass spectrometry. Mini Reviews in Medicinal Chemistry. 4: 313-24. PMID 15032677 DOI: 10.2174/1389557043487330  0.72
2003 Ericson C, Phung QT, Horn DM, Peters EC, Fitchett JR, Ficarro SB, Salomon AR, Brill LM, Brock A. An automated noncontact deposition interface for liquid chromatography matrix-assisted laser desorption/ionization mass spectrometry. Analytical Chemistry. 75: 2309-15. PMID 12918971 DOI: 10.1021/ac026409j  0.72
2003 Salomon AR, Ficarro SB, Brill LM, Brinker A, Phung QT, Ericson C, Sauer K, Brock A, Horn DM, Schultz PG, Peters EC. Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry. Proceedings of the National Academy of Sciences of the United States of America. 100: 443-8. PMID 12522270 DOI: 10.1073/pnas.2436191100  0.72
2003 Ficarro S, Chertihin O, Westbrook VA, White F, Jayes F, Kalab P, Marto JA, Shabanowitz J, Herr JC, Hunt DF, Visconti PE. Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein/p97 during capacitation. The Journal of Biological Chemistry. 278: 11579-89. PMID 12509440 DOI: 10.1074/jbc.M202325200  0.72
2002 Thatte A, Ficarro S, Snapp KR, Wild MK, Vestweber D, Hunt DF, Ley KF. Binding of function-blocking mAbs to mouse and human P-selectin glycoprotein ligand-1 peptides with and without tyrosine sulfation. Journal of Leukocyte Biology. 72: 470-7. PMID 12223514  0.72
2002 Winssinger N, Ficarro S, Schultz PG, Harris JL. Profiling protein function with small molecule microarrays. Proceedings of the National Academy of Sciences of the United States of America. 99: 11139-44. PMID 12167675 DOI: 10.1073/pnas.172286899  0.72
2002 Gioeli D, Ficarro SB, Kwiek JJ, Aaronson D, Hancock M, Catling AD, White FM, Christian RE, Settlage RE, Shabanowitz J, Hunt DF, Weber MJ. Androgen receptor phosphorylation. Regulation and identification of the phosphorylation sites. The Journal of Biological Chemistry. 277: 29304-14. PMID 12015328 DOI: 10.1074/jbc.M204131200  0.72
2002 Ficarro SB, McCleland ML, Stukenberg PT, Burke DJ, Ross MM, Shabanowitz J, Hunt DF, White FM. Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae. Nature Biotechnology. 20: 301-5. PMID 11875433 DOI: 10.1038/nbt0302-301  0.72
2002 Evans AM, Zarling AL, Ficarro SB, Shabanowitz J, Engelhard VH, Hunt DF. Differential comparison of phosphorylated MHC class I HLA-A2.1 Peptides from three different cancer cell lines Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 27-28.  0.72
2002 Salomon A, Phung Q, Ericson C, Horn D, Brock A, Peters E, Ficarro SB. Rapid profiling of cellular tyrosine kinase cascades by affinity chromatography and mass spectrometry Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 361-362.  0.72
2002 Brock A, Horn DM, Shaw CM, Peters EC, Ericson C, Phung Q, Ficarro SB, Salomon AR. Automated liquid chromatography MALDI FT-ICR MS platform for proteomics: Automated high performance mass spectrometry and data analysis American Pharmaceutical Review. 5: 94-99.  0.72
2002 Peters EC, Brock A, Phung Q, Fitchett J, Horn DM, Ericson C, Ficarro SB, Salomon AR. Automated liquid chromatography MALDI FT-ICR MS platform for proteomics: Rationale for an Off-line approach and optimized implementation American Pharmaceutical Review. 5: 72-81.  0.72
2002 Brock A, Horn DM, Shaw CM, Peters EC, Ericson C, Phung Q, Ficarro S, Salomon A. Improved QFT-ICR MS instrument for proteomics Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 197-198.  0.72
2002 Horn DM, Brock A, Shaw C, Peters EC, Ericson C, Phung Q, Ficarro S, Salomon A. High throughput protein identification using MALDI FT-ICR Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 47-48.  0.72
2000 Rago C, Tocce K, Ficarro S, Masters G, Riggs J. Superantigen disruption of CD+ T and B lymphocyte homeostasis Immunobiology. 202: 508-518. PMID 11205378  0.72
2000 Zarling AL, Ficarro SB, White FM, Shabanowitz J, Hunt DF, Engelhard VH. Phosphorylated peptides are naturally processed and presented by major histocompatibility complex class I molecules in vivo. The Journal of Experimental Medicine. 192: 1755-62. PMID 11120772 DOI: 10.1084/jem.192.12.1755  0.72
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