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Stephen E. Leonard, Ph.D. - Publications

Affiliations: 
2011 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Chemical biology
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15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Kong L, Barber T, Aldinger J, Bowman L, Leonard S, Zhao J, Ding M. ROS generation is involved in titanium dioxide nanoparticle-induced AP-1 activation through p38 MAPK and ERK pathways in JB6 cells. Environmental Toxicology. 37: 237-244. PMID 34730869 DOI: 10.1002/tox.23393  0.328
2016 Crowther GJ, Hillesland HK, Keyloun KR, Reid MC, Lafuente-Monasterio MJ, Ghidelli-Disse S, Leonard SE, He P, Jones JC, Krahn MM, Mo JS, Dasari KS, Fox AM, Boesche M, El Bakkouri M, et al. Biochemical Screening of Five Protein Kinases from Plasmodium falciparum against 14,000 Cell-Active Compounds. Plos One. 11: e0149996. PMID 26934697 DOI: 10.1371/Journal.Pone.0149996  0.488
2014 Register AC, Leonard SE, Maly DJ. SH2-catalytic domain linker heterogeneity influences allosteric coupling across the SFK family. Biochemistry. 53: 6910-23. PMID 25302671 DOI: 10.1021/Bi5008194  0.333
2014 Leonard SE, Register AC, Krishnamurty R, Brighty GJ, Maly DJ. Divergent modulation of Src-family kinase regulatory interactions with ATP-competitive inhibitors. Acs Chemical Biology. 9: 1894-905. PMID 24946274 DOI: 10.1021/Cb500371G  0.492
2014 Vidadala RS, Ojo KK, Johnson SM, Zhang Z, Leonard SE, Mitra A, Choi R, Reid MC, Keyloun KR, Fox AM, Kennedy M, Silver-Brace T, Hume JC, Kappe S, Verlinde CL, et al. Development of potent and selective Plasmodium falciparum calcium-dependent protein kinase 4 (PfCDPK4) inhibitors that block the transmission of malaria to mosquitoes. European Journal of Medicinal Chemistry. 74: 562-73. PMID 24531197 DOI: 10.1016/J.Ejmech.2013.12.048  0.401
2013 Krishnamurty R, Brigham JL, Leonard SE, Ranjitkar P, Larson ET, Dale EJ, Merritt EA, Maly DJ. Active site profiling reveals coupling between domains in SRC-family kinases. Nature Chemical Biology. 9: 43-50. PMID 23143416 DOI: 10.1038/Nchembio.1118  0.562
2012 Barrett TJ, Pattison DI, Leonard SE, Carroll KS, Davies MJ, Hawkins CL. Inactivation of thiol-dependent enzymes by hypothiocyanous acid: role of sulfenyl thiocyanate and sulfenic acid intermediates. Free Radical Biology & Medicine. 52: 1075-85. PMID 22248862 DOI: 10.1016/J.Freeradbiomed.2011.12.024  0.459
2012 Paulsen CE, Truong TH, Garcia FJ, Homann A, Gupta V, Leonard SE, Carroll KS. Peroxide-dependent sulfenylation of the EGFR catalytic site enhances kinase activity. Nature Chemical Biology. 8: 57-64. PMID 22158416 DOI: 10.1038/Nchembio.736  0.389
2011 Leonard SE, Garcia FJ, Goodsell DS, Carroll KS. Redox-based probes for protein tyrosine phosphatases. Angewandte Chemie (International Ed. in English). 50: 4423-7. PMID 21504031 DOI: 10.1002/Anie.201007871  0.536
2011 Leonard SE, Carroll KS. Chemical 'omics' approaches for understanding protein cysteine oxidation in biology. Current Opinion in Chemical Biology. 15: 88-102. PMID 21130680 DOI: 10.1016/J.Cbpa.2010.11.012  0.482
2009 Depuydt M, Leonard SE, Vertommen D, Denoncin K, Morsomme P, Wahni K, Messens J, Carroll KS, Collet JF. A periplasmic reducing system protects single cysteine residues from oxidation. Science (New York, N.Y.). 326: 1109-11. PMID 19965429 DOI: 10.1126/Science.1179557  0.452
2009 Ding M, Kisin ER, Zhao J, Bowman L, Lu Y, Jiang B, Leonard S, Vallyathan V, Castranova V, Murray AR, Fadeel B, Shvedova AA. Size-dependent effects of tungsten carbide-cobalt particles on oxygen radical production and activation of cell signaling pathways in murine epidermal cells Toxicology and Applied Pharmacology. 241: 260-268. PMID 19747498 DOI: 10.1016/J.Taap.2009.09.004  0.322
2009 Leonard SE, Reddie KG, Carroll KS. Mining the thiol proteome for sulfenic acid modifications reveals new targets for oxidation in cells. Acs Chemical Biology. 4: 783-99. PMID 19645509 DOI: 10.1021/Cb900105Q  0.515
2008 Reddie KG, Seo YH, Muse Iii WB, Leonard SE, Carroll KS. A chemical approach for detecting sulfenic acid-modified proteins in living cells. Molecular Biosystems. 4: 521-31. PMID 18493649 DOI: 10.1039/B719986D  0.507
2001 Ding M, Shi X, Lu Y, Huang C, Leonard S, Roberts J, Antonini J, Castranova V, Vallyathan V. Induction of activator protein-1 through reactive oxygen species by crystalline silica in JB6 cells. Journal of Biological Chemistry. 276: 9108-9114. PMID 11096084 DOI: 10.1074/Jbc.M007666200  0.401
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