Jennifer A. Maynard, Ph.D. - Publications

Affiliations: 
2001 University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
discovery and development of protein therapeutics and applied immunology by capitalizing on state of the art protein engineering, directed evolution and systems biology technologies

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Acquaye-Seedah E, Huang Y, Sutherland JN, DiVenere AM, Maynard JA. Humanized monoclonal antibodies neutralize pertussis toxin by receptor blockade and reduced retrograde trafficking. Cellular Microbiology. e12948. PMID 30152075 DOI: 10.1111/cmi.12948  1
2018 Boehm DT, Hall JM, Wong TY, DiVenere A, Sen-Kilic E, Bevere JR, Bradford SD, Blackwood CB, Elkins C, DeRoos KA, Gray MC, Cooper CG, Varney ME, Maynard JA, Hewlett EL, et al. Evaluation of adenylate cyclase toxoid antigen in acellular pertussis vaccines using a challenge model in mice. Infection and Immunity. PMID 30012638 DOI: 10.1128/IAI.00857-17  0.32
2018 Ha Y, Ko S, Kim I, Huang Y, Mohanty K, Huh C, Maynard JA. Recent Advances Incorporating Superparamagnetic Nanoparticles into Immunoassays. Acs Applied Nano Materials. 1: 512-521. PMID 29911680 DOI: 10.1021/acsanm.7b00025  0.44
2018 Acquaye-Seedah E, Reczek EE, Russell HH, DiVenere AM, Sandman SO, Collins JH, Stein CA, Whitehead TA, Maynard JA. Characterization of individual human antibodies binding pertussis toxin stimulated by acellular immunization. Infection and Immunity. PMID 29581192 DOI: 10.1128/IAI.00004-18  0.44
2017 Laber JR, Dear BJ, Martins ML, Jackson DE, DiVenere A, Gollihar JD, Ellington AD, Truskett TM, Johnston KP, Maynard JA. Charge shielding prevents aggregation of supercharged GFP variants at high protein concentration. Molecular Pharmaceutics. PMID 28870080 DOI: 10.1021/acs.molpharmaceut.7b00322  0.68
2017 Entzminger KC, Hyun JM, Pantazes RJ, Patterson-Orazem AC, Qerqez AN, Frye ZP, Hughes RA, Ellington AD, Lieberman RL, Maranas CD, Maynard JA. De novo design of antibody complementarity determining regions binding a FLAG tetra-peptide. Scientific Reports. 7: 10295. PMID 28860479 DOI: 10.1038/s41598-017-10737-9  0.32
2016 Khan TA, Wang X, Maynard JA. Inclusion of an RGD Motif Alters Invasin Integrin-Binding Affinity and Specificity. Biochemistry. PMID 27015583 DOI: 10.1021/acs.biochem.5b01243  1
2016 Ha Y, Wang X, Liljestrand HM, Maynard JA, Katz LE. Bioavailability of fullerene under environmentally relevant conditions: Effects of humic acid and fetal bovine serum on accumulation in lipid bilayers and cellular uptake. Environmental Science & Technology. PMID 26943027 DOI: 10.1021/acs.est.5b04964  1
2015 Nguyen AW, Wagner EK, Laber JR, Goodfield LL, Smallridge WE, Harvill ET, Papin JF, Wolf RF, Padlan EA, Bristol A, Kaleko M, Maynard JA. A cocktail of humanized anti-pertussis toxin antibodies limits disease in murine and baboon models of whooping cough. Science Translational Medicine. 7: 316ra195. PMID 26631634 DOI: 10.1126/scitranslmed.aad0966  1
2015 Kowalsky CA, Faber MS, Nath A, Dann HE, Kelly VW, Liu L, Shanker P, Wagner EK, Maynard JA, Chan C, Whitehead TA. Rapid Fine Conformational Epitope Mapping Using Comprehensive Mutagenesis and Deep Sequencing. The Journal of Biological Chemistry. PMID 26296891 DOI: 10.1074/jbc.M115.676635  1
2015 Entzminger KC, Johnson JL, Hyun J, Lieberman RL, Maynard JA. Increased Fab thermoresistance via VH-targeted directed evolution. Protein Engineering, Design & Selection : Peds. PMID 26283664 DOI: 10.1093/protein/gzv037  1
2015 Johnson JL, Entzminger KC, Hyun J, Kalyoncu S, Heaner DP, Morales IA, Sheppard A, Gumbart JC, Maynard JA, Lieberman RL. Structural and biophysical characterization of an epitope-specific engineered Fab fragment and complexation with membrane proteins: implications for co-crystallization. Acta Crystallographica. Section D, Biological Crystallography. 71: 896-906. PMID 25849400 DOI: 10.1107/S1399004715001856  1
2015 Wang X, Maynard JA. The Bordetella adenylate cyclase repeat-in-toxin (RTX) domain is immunodominant and elicits neutralizing antibodies. The Journal of Biological Chemistry. 290: 3576-91. PMID 25505186 DOI: 10.1074/jbc.M114.585281  1
2014 Seedah EA, Frye ZP, Maynard JA. Immunotherapeutic Approaches To Prevent Cytomegalovirus-Mediated Disease. Microbiology Spectrum. 2: AID-0009-2013. PMID 26082112 DOI: 10.1128/microbiolspec.AID-0009-13  1
2014 Kalyoncu S, Hyun J, Pai JC, Johnson JL, Entzminger K, Jain A, Heaner DP, Morales IA, Truskett TM, Maynard JA, Lieberman RL. Effects of protein engineering and rational mutagenesis on crystal lattice of single chain antibody fragments. Proteins. 82: 1884-95. PMID 24615866 DOI: 10.1002/prot.24542  1
2013 Wang XZ, Coljee VW, Maynard JA. Back to the future: recombinant polyclonal antibody therapeutics. Current Opinion in Chemical Engineering. 2: 405-415. PMID 24443710 DOI: 10.1016/j.coche.2013.08.005  1
2013 Panthani MG, Khan TA, Reid DK, Hellebusch DJ, Rasch MR, Maynard JA, Korgel BA. In vivo whole animal fluorescence imaging of a microparticle-based oral vaccine containing (CuInSe(x)S(2-x))/ZnS core/shell quantum dots. Nano Letters. 13: 4294-8. PMID 23915166 DOI: 10.1021/nl402054w  1
2013 Miller MA, Rodrigues MA, Glass MA, Singh SK, Johnston KP, Maynard JA. Frozen-state storage stability of a monoclonal antibody: aggregation is impacted by freezing rate and solute distribution. Journal of Pharmaceutical Sciences. 102: 1194-208. PMID 23400717 DOI: 10.1002/jps.23473  1
2013 Borwankar AU, Dinin AK, Laber JR, Twu A, Wilson BK, Maynard JA, Truskett TM, Johnston KP. Tunable equilibrium nanocluster dispersions at high protein concentrations Soft Matter. 9: 1766-1771. DOI: 10.1039/c2sm27480a  1
2012 Roy BM, Zhukov DV, Maynard JA. Flanking residues are central to DO11.10 T cell hybridoma stimulation by ovalbumin 323-339. Plos One. 7: e47585. PMID 23110081 DOI: 10.1371/journal.pone.0047585  1
2012 Miller MA, Khan TA, Kaczorowski KJ, Wilson BK, Dinin AK, Borwankar AU, Rodrigues MA, Truskett TM, Johnston KP, Maynard JA. Antibody nanoparticle dispersions formed with mixtures of crowding molecules retain activity and In Vivo bioavailability Journal of Pharmaceutical Sciences. 101: 3763-3778. PMID 22777686 DOI: 10.1002/jps.23256  1
2012 Entzminger KC, Chang C, Myhre RO, McCallum KC, Maynard JA. The Skp chaperone helps fold soluble proteins in vitro by inhibiting aggregation. Biochemistry. 51: 4822-34. PMID 22650963 DOI: 10.1021/bi300412y  1
2012 Johnston KP, Maynard JA, Truskett TM, Borwankar AU, Miller MA, Wilson BK, Dinin AK, Khan TA, Kaczorowski KJ. Concentrated dispersions of equilibrium protein nanoclusters that reversibly dissociate into active monomers Acs Nano. 6: 1357-1369. PMID 22260218 DOI: 10.1021/nn204166z  1
2012 Im H, Sutherland JN, Maynard JA, Oh SH. Nanohole-based surface plasmon resonance instruments with improved spectral resolution quantify a broad range of antibody-ligand binding kinetics. Analytical Chemistry. 84: 1941-7. PMID 22235895 DOI: 10.1021/ac300070t  1
2012 Pai JC, Entzminger KC, Maynard JA. Restriction enzyme-free construction of random gene mutagenesis libraries in Escherichia coli. Analytical Biochemistry. 421: 640-8. PMID 22155067 DOI: 10.1016/j.ab.2011.11.009  1
2012 Frye ZP, Roy BM, Maynard JA. Finding murine t-cell receptor repertoire shifts due to ovalbumin challenges using high throughput sequencing Aiche Annual Meeting, Conference Proceedings 1
2011 Lieberman RL, Culver JA, Entzminger KC, Pai JC, Maynard JA. Crystallization chaperone strategies for membrane proteins. Methods (San Diego, Calif.). 55: 293-302. PMID 21854852 DOI: 10.1016/j.ymeth.2011.08.004  1
2011 Sutherland JN, Chang C, Yoder SM, Rock MT, Maynard JA. Antibodies recognizing protective pertussis toxin epitopes are preferentially elicited by natural infection versus acellular immunization. Clinical and Vaccine Immunology : Cvi. 18: 954-62. PMID 21508166 DOI: 10.1128/CVI.00561-10  1
2011 Pai JC, Culver JA, Drury JE, Motani RS, Lieberman RL, Maynard JA. Conversion of scFv peptide-binding specificity for crystal chaperone development. Protein Engineering, Design & Selection : Peds. 24: 419-28. PMID 21217145 DOI: 10.1093/protein/gzq120  1
2009 Maynard JA, Lindquist NC, Sutherland JN, Lesuffleur A, Warrington AE, Rodriguez M, Oh SH. Surface plasmon resonance for high-throughput ligand screening of membrane-bound proteins. Biotechnology Journal. 4: 1542-58. PMID 19918786 DOI: 10.1002/biot.200900195  1
2009 Sutherland JN, Maynard JA. Characterization of a key neutralizing epitope on pertussis toxin recognized by monoclonal antibody 1B7. Biochemistry. 48: 11982-93. PMID 19899804 DOI: 10.1021/bi901532z  1
2009 Leysath CE, Monzingo AF, Maynard JA, Barnett J, Georgiou G, Iverson BL, Robertus JD. Crystal structure of the engineered neutralizing antibody M18 complexed to domain 4 of the anthrax protective antigen. Journal of Molecular Biology. 387: 680-93. PMID 19361425 DOI: 10.1016/j.jmb.2009.02.003  1
2009 Pai JC, Sutherland JN, Maynard JA. Progress towards recombinant anti-infective antibodies. Recent Patents On Anti-Infective Drug Discovery. 4: 1-17. PMID 19149692 DOI: 10.2174/157489109787236319  1
2009 Ramalingam KI, Tomshine JR, Maynard JA, Kaznessis YN. Forward engineering of synthetic bio-logical AND gates Biochemical Engineering Journal. 47: 38-47. DOI: 10.1016/j.bej.2009.06.014  1
2008 Sivasubramanian A, Maynard JA, Gray JJ. Modeling the structure of mAb 14B7 bound to the anthrax protective antigen. Proteins. 70: 218-30. PMID 17671962 DOI: 10.1002/prot.21595  1
2008 Pai JC, Maynard J. Engineering hyper-crystallizable single chain antibodies for crystallization scaffold Aiche Annual Meeting, Conference Proceedings 1
2007 Feng D, Bond CJ, Ely LK, Maynard J, Garcia KC. Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'. Nature Immunology. 8: 975-83. PMID 17694060 DOI: 10.1038/ni1502  1
2007 Maynard JA, Myhre R, Roy B. Microarrays in infection and immunity. Current Opinion in Chemical Biology. 11: 306-15. PMID 17500025 DOI: 10.1016/j.cbpa.2007.01.727  1
2005 Maynard J, Adams EJ, Krogsgaard M, Petersson K, Liu CW, Garcia KC. High-level bacterial secretion of single-chain αβ T-cell receptors Journal of Immunological Methods. 306: 51-67. PMID 16198365 DOI: 10.1016/j.jim.2005.07.022  1
2005 Maynard J, Petersson K, Wilson DH, Adams EJ, Blondelle SE, Boulanger MJ, Wilson DB, Garcia KC. Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: insights into MHC bias and antigen specificity. Immunity. 22: 81-92. PMID 15664161 DOI: 10.1016/j.immuni.2004.11.015  1
2002 Maynard JA, Maassen CB, Leppla SH, Brasky K, Patterson JL, Iverson BL, Georgiou G. Protection against anthrax toxin by recombinant antibody fragments correlates with antigen affinity. Nature Biotechnology. 20: 597-601. PMID 12042864 DOI: 10.1038/nbt0602-597  1
2002 Maynard JA, Chen G, Georgiou G, Iverson BL. In vitro scanning-saturation mutagenesis. Methods in Molecular Biology (Clifton, N.J.). 182: 149-63. PMID 11768962  1
2001 Mao Y, Chen J, Maynard JA, Zhang B, Quiocho FA. A novel all helix fold of the AP180 amino-terminal domain for phosphoinositide binding and clathrin assembly in synaptic vesicle endocytosis. Cell. 104: 433-40. PMID 11239400 DOI: 10.1016/S0092-8674(01)00230-6  1
2000 Maynard J, Georgiou G. Antibody engineering Annual Review of Biomedical Engineering. 2: 339-376. PMID 11701516  1
2000 Maynard J, Garza D, Finley C, Tsurikov M, Ulloa F, Barr R. Addressing Future Engineering Educators Through ASEE Asee Annual Conference Proceedings. 717-719.  1
1999 Maynard J, Razatos A. The evolution of engineering: Incorporating biology into traditional engineering curriculum Asee Annual Conference Proceedings. 4965-4972.  1
1998 Yee DC, Maynard JA, Wood TK. Rhizoremediation of trichloroethylene by a recombinant, root-colonizing Pseudomonas fluorescens strain expressing toluene ortho-monooxygenase constitutively. Applied and Environmental Microbiology. 64: 112-8. PMID 9435067  1
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