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Jeffrey A. Melvin, Ph.D. - Publications

Affiliations: 
2012 Biochemistry Duke University, Durham, NC 
Area:
chemical biology, mechanistic enzymology and molecular medicine
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16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Melvin JA, Gaston JR, Phillips SN, Springer MJ, Marshall CW, Shanks RMQ, Bomberger JM. Pseudomonas aeruginosa Contact-Dependent Growth Inhibition Plays Dual Role in Host-Pathogen Interactions. Msphere. 2. PMID 29152577 DOI: 10.1128/mSphere.00336-17  0.357
2016 Hoffman C, Eby J, Gray M, Damron FH, Melvin J, Cotter P, Hewlett E. Bordetella Adenylate Cyclase Toxin Interacts with Filamentous Hemagglutinin to Inhibit Biofilm Formation in vitro. Molecular Microbiology. PMID 27731909 DOI: 10.1111/Mmi.13551  0.423
2016 Melvin JA, Bomberger JM. Compromised Defenses: Exploitation of Epithelial Responses During Viral-Bacterial Co-Infection of the Respiratory Tract. Plos Pathogens. 12: e1005797. PMID 27631788 DOI: 10.1371/Journal.Ppat.1005797  0.378
2016 Melvin JA, Montelaro RC, Bomberger JM. Clinical potential of engineered cationic antimicrobial peptides against drug resistant biofilms. Expert Review of Anti-Infective Therapy. PMID 27626708 DOI: 10.1080/14787210.2016.1236687  0.342
2016 Melvin JA, Lashua LP, Kiedrowski MR, Yang G, Deslouches B, Montelaro RC, Bomberger JM. Simultaneous Antibiofilm and Antiviral Activities of an Engineered Antimicrobial Peptide during Virus-Bacterium Coinfection. Msphere. 1. PMID 27303744 DOI: 10.1128/mSphere.00083-16  0.373
2016 Lashua LP, Melvin JA, Deslouches B, Pilewski JM, Montelaro RC, Bomberger JM. Engineered cationic antimicrobial peptide (eCAP) prevents Pseudomonas aeruginosa biofilm growth on airway epithelial cells. The Journal of Antimicrobial Chemotherapy. PMID 27231279 DOI: 10.1093/Jac/Dkw143  0.442
2016 Deschamps JD, Ogunsola AF, Jameson JB, Yasgar A, Flitter BA, Freedman CJ, Melvin JA, Maloney DJ, Jadhav A, Simeonov A, Bomberger JM, Holman TR, Nguyen JV. Biochemical/Cellular Characterization and Inhibitor discovery of Pseudomonas aeruginosa 15-Lipoxygenase. Biochemistry. PMID 27226387 DOI: 10.1021/Acs.Biochem.6B00338  0.47
2015 Melvin JA, Scheller EV, Noël CR, Cotter PA. New Insight into Filamentous Hemagglutinin Secretion Reveals a Role for Full-Length FhaB in Bordetella Virulence. Mbio. 6. PMID 26286694 DOI: 10.1128/Mbio.01189-15  0.342
2015 Scheller EV, Melvin JA, Sheets AJ, Cotter PA. Cooperative roles for fimbria and filamentous hemagglutinin in Bordetella adherence and immune modulation. Mbio. 6: e00500-15. PMID 26015497 DOI: 10.1128/Mbio.00500-15  0.375
2013 McCafferty DG, Melvin JA. Sortases Handbook of Proteolytic Enzymes. 2: 2459-2465. DOI: 10.1016/B978-0-12-382219-2.00549-4  0.625
2012 Noël CR, Mazar J, Melvin JA, Sexton JA, Cotter PA. The prodomain of the Bordetella two-partner secretion pathway protein FhaB remains intracellular yet affects the conformation of the mature C-terminal domain. Molecular Microbiology. 86: 988-1006. PMID 23035892 DOI: 10.1111/Mmi.12036  0.323
2011 Melvin JA, Murphy CF, Dubois LG, Thompson JW, Moseley MA, McCafferty DG. Staphylococcus aureus sortase A contributes to the Trojan horse mechanism of immune defense evasion with its intrinsic resistance to Cys184 oxidation. Biochemistry. 50: 7591-9. PMID 21812416 DOI: 10.1021/Bi200844H  0.702
2011 Hu X, Hu H, Melvin JA, Clancy KW, McCafferty DG, Yang W. Autocatalytic intramolecular isopeptide bond formation in gram-positive bacterial pili: a QM/MM simulation. Journal of the American Chemical Society. 133: 478-85. PMID 21142157 DOI: 10.1021/Ja107513T  0.637
2010 Clancy KW, Melvin JA, McCafferty DG. Sortase transpeptidases: insights into mechanism, substrate specificity, and inhibition. Biopolymers. 94: 385-96. PMID 20593474 DOI: 10.1002/Bip.21472  0.685
2010 Clancy KW, Melvin JA, McCafferty DG. Erratum: Invited Review: Sortase transpeptidases: Insights into mechanism, substrate specificity, and inhibition Biopolymers. 94: 681-681. DOI: 10.1002/Bip.21529  0.682
2009 Race PR, Bentley ML, Melvin JA, Crow A, Hughes RK, Smith WD, Sessions RB, Kehoe MA, McCafferty DG, Banfield MJ. Crystal structure of Streptococcus pyogenes sortase A: implications for sortase mechanism. The Journal of Biological Chemistry. 284: 6924-33. PMID 19129180 DOI: 10.1074/Jbc.M805406200  0.693
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