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Corey P. Causey, Ph.D. - Publications

Affiliations: 
2007 Duke University, Durham, NC 
Area:
biocatalysis/applied enzymology, ligand binding and the activity of water, and the synthesis of novel donors of nitric oxide
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 DuBose MB, Sartawi T, Sawatzky TM, Causey CP, Rehman FK, Knuckley B. A peptoid-based inhibitor of Protein Arginine Methyltransferase 1 (PRMT1) induces apoptosis and autophagy in cancer cells. The Journal of Biological Chemistry. 102205. PMID 35764172 DOI: 10.1016/j.jbc.2022.102205  0.744
2020 Mann SA, DeMart MK, May B, Causey CP, Knuckley B. Histone H4-based peptoids are inhibitors of Protein Arginine Methyltransferase 1 (PRMT1). The Biochemical Journal. PMID 32716034 DOI: 10.1042/Bcj20200534  0.758
2019 Mann SA, Salsburg A, Causey CP, Knuckley B. The development and characterization of a chemical probe targeting PRMT1 over PRMT5. Bioorganic & Medicinal Chemistry. 27: 224-229. PMID 30529151 DOI: 10.1016/J.Bmc.2018.12.001  0.738
2015 Witalison EE, Cui X, Causey CP, Thompson PR, Hofseth LJ. Molecular targeting of protein arginine deiminases to suppress colitis and prevent colon cancer. Oncotarget. PMID 26440311 DOI: 10.18632/Oncotarget.5937  0.524
2015 Creech C, Kanaujia M, Causey CP. Synthesis and evaluation of 2-ethynyl-adenosine-5'-triphosphate as a chemical reporter for protein AMPylation. Organic & Biomolecular Chemistry. 13: 8550-5. PMID 26173047 DOI: 10.1039/C5Ob01081K  0.415
2015 Kholia S, Jorfi S, Thompson PR, Causey CP, Nicholas AP, Inal JM, Lange S. A novel role for peptidylarginine deiminases in microvesicle release reveals therapeutic potential of PAD inhibition in sensitizing prostate cancer cells to chemotherapy. Journal of Extracellular Vesicles. 4: 26192. PMID 26095379 DOI: 10.3402/Jev.V4.26192  0.525
2015 Marchenko M, Thomson A, Ellis TN, Knuckley B, Causey CP. Development of a clickable activity-based protein profiling (ABPP) probe for agmatine deiminases. Bioorganic & Medicinal Chemistry. 23: 2159-67. PMID 25819331 DOI: 10.1016/J.Bmc.2015.03.013  0.743
2015 Witalison EE, Cui X, Hofseth AB, Subramanian V, Causey CP, Thompson PR, Hofseth LJ. Inhibiting protein arginine deiminases has antioxidant consequences. The Journal of Pharmacology and Experimental Therapeutics. 353: 64-70. PMID 25635139 DOI: 10.1124/Jpet.115.222745  0.465
2015 Witalison EE, Cui X, Causey CP, Thompson PR, Hofseth LJ. Abstract 238: Citrullination of miRNA regulators by PADs: A potential mechanism for the promotion of colitis and colitis-associated colorectal cancer Cancer Research. 75: 238-238. DOI: 10.1158/1538-7445.Am2015-238  0.466
2014 Thomson A, O'Connor S, Knuckley B, Causey CP. Design, synthesis, and in vitro evaluation of an activity-based protein profiling (ABPP) probe targeting agmatine deiminases. Bioorganic & Medicinal Chemistry. 22: 4602-8. PMID 25127464 DOI: 10.1016/J.Bmc.2014.07.028  0.751
2014 Sund JB, Causey CP, Wolter SD, Parker CB, Stoner BR, Toone EJ, Glass JT. Diamond surface functionalization with biomimicry - Amine surface tether and thiol moiety for electrochemical sensors Applied Surface Science. 301: 293-299. DOI: 10.1016/J.Apsusc.2014.02.067  0.499
2012 McElwee JL, Mohanan S, Griffith OL, Breuer HC, Anguish LJ, Cherrington BD, Palmer AM, Howe LR, Subramanian V, Causey CP, Thompson PR, Gray JW, Coonrod SA. Identification of PADI2 as a potential breast cancer biomarker and therapeutic target. Bmc Cancer. 12: 500. PMID 23110523 DOI: 10.1186/1471-2407-12-500  0.508
2012 Kan R, Jin M, Subramanian V, Causey CP, Thompson PR, Coonrod SA. Potential role for PADI-mediated histone citrullination in preimplantation development. Bmc Developmental Biology. 12: 19. PMID 22712504 DOI: 10.1186/1471-213X-12-19  0.514
2012 Mohamed BM, Verma NK, Davies AM, McGowan A, Crosbie-Staunton K, Prina-Mello A, Kelleher D, Botting CH, Causey CP, Thompson PR, Pruijn GJ, Kisin ER, Tkach AV, Shvedova AA, Volkov Y. Citrullination of proteins: a common post-translational modification pathway induced by different nanoparticles in vitro and in vivo. Nanomedicine (London, England). 7: 1181-95. PMID 22625207 DOI: 10.2217/Nnm.11.177  0.517
2012 Jones JE, Slack JL, Fang P, Zhang X, Subramanian V, Causey CP, Coonrod SA, Guo M, Thompson PR. Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors. Acs Chemical Biology. 7: 160-5. PMID 22004374 DOI: 10.1021/Cb200258Q  0.783
2011 Causey CP, Jones JE, Slack JL, Kamei D, Jones LE, Subramanian V, Knuckley B, Ebrahimi P, Chumanevich AA, Luo Y, Hashimoto H, Sato M, Hofseth LJ, Thompson PR. The development of N-α-(2-carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-F-amidine) and N-α-(2-carboxyl)benzoyl-N(5)-(2-chloro-1-iminoethyl)-l-ornithine amide (o-Cl-amidine) as second generation protein arginine deiminase (PAD) inhibitors. Journal of Medicinal Chemistry. 54: 6919-35. PMID 21882827 DOI: 10.1021/Jm2008985  0.76
2011 Obianyo O, Causey CP, Jones JE, Thompson PR. Activity-based protein profiling of protein arginine methyltransferase 1. Acs Chemical Biology. 6: 1127-35. PMID 21838253 DOI: 10.1021/Cb2001473  0.77
2011 Zhang X, Gamble MJ, Stadler S, Cherrington BD, Causey CP, Thompson PR, Roberson MS, Kraus WL, Coonrod SA. Genome-wide analysis reveals PADI4 cooperates with Elk-1 to activate c-Fos expression in breast cancer cells. Plos Genetics. 7: e1002112. PMID 21655091 DOI: 10.1371/Journal.Pgen.1002112  0.51
2011 Lange S, Gögel S, Leung KY, Vernay B, Nicholas AP, Causey CP, Thompson PR, Greene ND, Ferretti P. Protein deiminases: new players in the developmentally regulated loss of neural regenerative ability. Developmental Biology. 355: 205-14. PMID 21539830 DOI: 10.1016/J.Ydbio.2011.04.015  0.479
2011 Chumanevich AA, Causey CP, Knuckley BA, Jones JE, Poudyal D, Chumanevich AP, Davis T, Matesic LE, Thompson PR, Hofseth LJ. Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor. American Journal of Physiology. Gastrointestinal and Liver Physiology. 300: G929-38. PMID 21415415 DOI: 10.1152/Ajpgi.00435.2010  0.753
2011 Willis VC, Gizinski AM, Banda NK, Causey CP, Knuckley B, Cordova KN, Luo Y, Levitt B, Glogowska M, Chandra P, Kulik L, Robinson WH, Arend WP, Thompson PR, Holers VM. N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis. Journal of Immunology (Baltimore, Md. : 1950). 186: 4396-404. PMID 21346230 DOI: 10.4049/Jimmunol.1001620  0.768
2011 Slack JL, Causey CP, Luo Y, Thompson PR. Development and use of clickable activity based protein profiling agents for protein arginine deiminase 4. Acs Chemical Biology. 6: 466-76. PMID 21265574 DOI: 10.1021/Cb1003515  0.634
2011 Slack JL, Causey CP, Thompson PR. Protein arginine deiminase 4: a target for an epigenetic cancer therapy. Cellular and Molecular Life Sciences : Cmls. 68: 709-20. PMID 20706768 DOI: 10.1007/S00018-010-0480-X  0.572
2010 Jones JE, Dreyton CJ, Flick H, Causey CP, Thompson PR. Mechanistic studies of agmatine deiminase from multiple bacterial species. Biochemistry. 49: 9413-23. PMID 20939536 DOI: 10.1021/Bi101405Y  0.751
2010 Knuckley B, Jones JE, Bachovchin DA, Slack J, Causey CP, Brown SJ, Rosen H, Cravatt BF, Thompson PR. A fluopol-ABPP HTS assay to identify PAD inhibitors. Chemical Communications (Cambridge, England). 46: 7175-7. PMID 20740228 DOI: 10.1039/C0Cc02634D  0.767
2010 Obianyo O, Causey CP, Osborne TC, Jones JE, Lee YH, Stallcup MR, Thompson PR. A chloroacetamidine-based inactivator of protein arginine methyltransferase 1: design, synthesis, and in vitro and in vivo evaluation. Chembiochem : a European Journal of Chemical Biology. 11: 1219-23. PMID 20480486 DOI: 10.1002/Cbic.201000209  0.789
2010 Knuckley B, Causey CP, Jones JE, Bhatia M, Dreyton CJ, Osborne TC, Takahara H, Thompson PR. Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3. Biochemistry. 49: 4852-63. PMID 20469888 DOI: 10.1021/Bi100363T  0.795
2010 Jones JE, Causey CP, Lovelace L, Knuckley B, Flick H, Lebioda L, Thompson PR. Characterization and inactivation of an agmatine deiminase from Helicobacter pylori. Bioorganic Chemistry. 38: 62-73. PMID 20036411 DOI: 10.1016/J.Bioorg.2009.11.004  0.76
2010 Knuckley B, Causey CP, Pellechia PJ, Cook PF, Thompson PR. Haloacetamidine-based inactivators of protein arginine deiminase 4 (PAD4): Evidence that general acid catalysis promotes efficient inactivation Chembiochem. 11: 161-165. PMID 20014086 DOI: 10.1002/Cbic.200900698  0.783
2009 Jones JE, Causey CP, Knuckley B, Slack-Noyes JL, Thompson PR. Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential Current Opinion in Drug Discovery and Development. 12: 616-627. PMID 19736621  0.763
2008 Causey CP, Thompson PR. An improved synthesis of haloaceteamidine-based inactivators of protein arginine deiminase 4 (PAD4). Tetrahedron Letters. 49: 4383-4385. PMID 19587776 DOI: 10.1016/J.Tetlet.2008.05.021  0.6
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