Markos Koutmos, Ph.D. - Publications

Affiliations: 
2005 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Design, Synthesis, Structures and Reactivities of Metal Clusters and Supramolecules

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Sen A, Karasik A, Shanmuganathan A, Mirkovic E, Koutmos M, Cox RT. Loss of the mitochondrial protein-only ribonuclease P complex causes aberrant tRNA processing and lethality in Drosophila. Nucleic Acids Research. PMID 27131785 DOI: 10.1093/nar/gkw338  0.52
2016 Howard MJ, Karasik A, Klemm BP, Mei C, Shanmuganathan A, Fierke CA, Koutmos M. Differential substrate recognition by isozymes of plant protein-only Ribonuclease P. Rna (New York, N.Y.). PMID 26966150 DOI: 10.1261/rna.055541.115  0.52
2015 Karasik A, Shanmuganathan A, Howard MJ, Fierke CA, Koutmos M. Nuclear Protein-only ribonuclease P 2 Structure and Biochemical Characterization Provide Insight Into the Conserved Properties of tRNA 5'-end Processing Enzymes. Journal of Molecular Biology. PMID 26655022 DOI: 10.1016/j.jmb.2015.11.025  0.52
2015 Yamada K, Gherasim C, Banerjee R, Koutmos M. Structure of Human B12 trafficking protein CblD reveals molecular mimicry and identifies a new subfamily of Nitro-FMN reductases. The Journal of Biological Chemistry. PMID 26364851 DOI: 10.1074/jbc.M115.682435  0.52
2015 Ganu RS, Ishida Y, Koutmos M, Kolokotronis SO, Roca AL, Garrow TA, Schook LB. Evolutionary Analyses and Natural Selection of Betaine-Homocysteine S-Methyltransferase (BHMT) and BHMT2 Genes. Plos One. 10: e0134084. PMID 26213999 DOI: 10.1371/journal.pone.0134084  0.52
2014 Mládková J, Hladílková J, Diamond CE, Tryon K, Yamada K, Garrow TA, Jungwirth P, Koutmos M, Jiráček J. Specific potassium ion interactions facilitate homocysteine binding to betaine-homocysteine S-methyltransferase. Proteins. 82: 2552-64. PMID 24895213 DOI: 10.1002/prot.24619  0.52
2013 Lofgren M, Koutmos M, Banerjee R. Autoinhibition and signaling by the switch II motif in the G-protein chaperone of a radical B12 enzyme. The Journal of Biological Chemistry. 288: 30980-9. PMID 23996001 DOI: 10.1074/jbc.M113.499970  0.52
2013 Ganu R, Garrow T, Koutmos M, Rund L, Schook LB. Splicing variants of the porcine betaine-homocysteine S-methyltransferase gene: implications for mammalian metabolism. Gene. 529: 228-37. PMID 23948084 DOI: 10.1016/j.gene.2013.07.103  0.52
2013 Lofgren M, Padovani D, Koutmos M, Banerjee R. A switch III motif relays signaling between a B12 enzyme and its G-protein chaperone Nature Chemical Biology. 9: 535-541. PMID 23873214 DOI: 10.1038/nchembio.1298  0.52
2013 Yadav PK, Yamada K, Chiku T, Koutmos M, Banerjee R. Structure and kinetic analysis of H2S production by human mercaptopyruvate sulfurtransferase. The Journal of Biological Chemistry. 288: 20002-13. PMID 23698001 DOI: 10.1074/jbc.M113.466177  0.52
2013 Howard MJ, Liu X, Lim WH, Klemm BP, Fierke CA, Koutmos M, Engelke DR. RNase P enzymes: divergent scaffolds for a conserved biological reaction. Rna Biology. 10: 909-14. PMID 23595059 DOI: 10.4161/rna.24513  0.52
2012 Howard MJ, Lim WH, Fierke CA, Koutmos M. Mitochondrial ribonuclease P structure provides insight into the evolution of catalytic strategies for precursor-tRNA 5' processing. Proceedings of the National Academy of Sciences of the United States of America. 109: 16149-54. PMID 22991464 DOI: 10.1073/pnas.1209062109  0.52
2011 Koutmos M, Gherasim C, Smith JL, Banerjee R. Structural basis of multifunctionality in a vitamin B12-processing enzyme. The Journal of Biological Chemistry. 286: 29780-7. PMID 21697092 DOI: 10.1074/jbc.M111.261370  0.52
2011 Koutmos M, Kabil O, Smith JL, Banerjee R. Structural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine β-synthase (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 49 (20958-20963) DOI: 10.1073/pnas.1011448107) Proceedings of the National Academy of Sciences of the United States of America. 108: 4512. DOI: 10.1073/pnas.1102185108  0.52
2010 Koutmos M, Kabil O, Smith JL, Banerjee R. Structural basis for substrate activation and regulation by cystathionine beta-synthase (CBS) domains in cystathionine {beta}-synthase. Proceedings of the National Academy of Sciences of the United States of America. 107: 20958-63. PMID 21081698 DOI: 10.1073/pnas.1011448107  0.52
2010 Hsieh J, Koutmou KS, Rueda D, Koutmos M, Walter NG, Fierke CA. A divalent cation stabilizes the active conformation of the B. subtilis RNase P x pre-tRNA complex: a role for an inner-sphere metal ion in RNase P. Journal of Molecular Biology. 400: 38-51. PMID 20434461 DOI: 10.1016/j.jmb.2010.04.050  0.52
2009 Koutmos M, Datta S, Pattridge KA, Smith JL, Matthews RG. Insights into the reactivation of cobalamin-dependent methionine synthase. Proceedings of the National Academy of Sciences of the United States of America. 106: 18527-32. PMID 19846791 DOI: 10.1073/pnas.0906132106  0.52
2009 Vanek V, Budesínský M, Kabeleová P, Sanda M, Kozísek M, Hanclová I, Mládková J, Brynda J, Rosenberg I, Koutmos M, Garrow TA, Jirácek J. Structure-activity study of new inhibitors of human betaine-homocysteine S-methyltransferase. Journal of Medicinal Chemistry. 52: 3652-65. PMID 19534555 DOI: 10.1021/jm8015798  0.52
2008 Matthews RG, Koutmos M, Datta S. Cobalamin-dependent and cobamide-dependent methyltransferases. Current Opinion in Structural Biology. 18: 658-66. PMID 19059104 DOI: 10.1016/j.sbi.2008.11.005  0.52
2008 Datta S, Koutmos M, Pattridge KA, Ludwig ML, Matthews RG. A disulfide-stabilized conformer of methionine synthase reveals an unexpected role for the histidine ligand of the cobalamin cofactor. Proceedings of the National Academy of Sciences of the United States of America. 105: 4115-20. PMID 18332423 DOI: 10.1073/pnas.0800329105  0.52
2008 Koutmos M, Pejchal R, Bomer TM, Matthews RG, Smith JL, Ludwig ML. Metal active site elasticity linked to activation of homocysteine in methionine synthases. Proceedings of the National Academy of Sciences of the United States of America. 105: 3286-91. PMID 18296644 DOI: 10.1073/pnas.0709960105  0.52
2008 Szegedi SS, Castro CC, Koutmos M, Garrow TA. Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase. The Journal of Biological Chemistry. 283: 8939-45. PMID 18230605 DOI: 10.1074/jbc.M710449200  0.52
2008 Koutmos M, Georgakaki IP, Tsiolis P, Coucouvanis D. Synthesis and characterization of MoFe3S4 and Mo 2Fe2S4 single cubanes Zeitschrift Fur Anorganische Und Allgemeine Chemie. 634: 255-261. DOI: 10.1002/zaac.200700419  0.52
2006 Xiao Y, Koutmos M, Case DA, Coucouvanis D, Wang H, Cramer SP. Dynamics of an [Fe4S4(SPh)4]2- cluster explored via IR, Raman, and nuclear resonance vibrational spectroscopy (NRVS)-analysis using 36S substitution, DFT calculations, and empirical force fields. Dalton Transactions (Cambridge, England : 2003). 2192-201. PMID 16673033 DOI: 10.1039/b513331a  0.52
2006 Koutmos M, Georgakaki IP, Coucouvanis D. Borohydride, azide, and chloride anions as terminal ligands on Fe/Mo/S clusters. Synthesis, structure and characterization of [(Cl4-cat)(PPr3) MoFe3S4(X)2]2(Bu4N)4 and [(Cl4-cat)(PPr3)MoFe3S4 (PPr3)(X)]2(Bu4N)2 (X = N3-, BH4-, Cl-) double-fused cubanes. NMR reactivity studies of [(Cl4-cat)(PPr3) MoFe3S4(BH4)2]2(Bu4N)4. Inorganic Chemistry. 45: 3648-56. PMID 16634597 DOI: 10.1021/ic052156b  0.52
2006 Koutmos M, Coucouvanis D. Metal clusters as ligands. Substitution of fe ions in Fe/Mo/S clusters by thiophilic CuI ions. Inorganic Chemistry. 45: 1421-3. PMID 16471948 DOI: 10.1021/ic051860p  0.52
2005 Smith MC, Xiao Y, Wang H, George SJ, Coucouvanis D, Koutmos M, Sturhahn W, Alp EE, Zhao J, Cramer SP. Normal-mode analysis of FeCl4- and Fe2S2Cl42- via vibrational mössbauer, resonance Raman, and FT-IR spectroscopies. Inorganic Chemistry. 44: 5562-70. PMID 16060605 DOI: 10.1021/ic0482584  0.52
2005 Koutmos M, Kalyvas H, Sanakis Y, Simopoulos A, Coucouvanis D. Systematic synthesis of heterometallic Ni/Fe/S and Cu/Fe/S clusters with a pentlandite-like M8S6 core. Journal of the American Chemical Society. 127: 3706-7. PMID 15771499 DOI: 10.1021/ja042938o  0.52
2005 Koutmos M, Coucouvanis D. Metal clusters as ligands: substitution of Fe ions in Fe/Mo/S clusters by thiophilic Cu(I) ions to give clusters with [Cu4Mo2Fe2S8]4+ and [Cu5Mo3Fe4S11]6+ cores. Angewandte Chemie (International Ed. in English). 44: 1971-4. PMID 15724256 DOI: 10.1002/anie.200462596  0.52
2005 Demadis KD, Katarachia SD, Koutmos M. Crystal growth and characterization of zinc-(amino-tris- (methylenephosphonate)) organic-inorganic hybrid networks and their inhibiting effect on metallic corrosion Inorganic Chemistry Communications. 8: 254-258. DOI: 10.1016/j.inoche.2004.12.019  0.52
2004 Koutmos M, Coucouvanis D. Borohydride anions as terminal ligands on a Fe/Mo/S cluster. Synthesis, structure, and characterization of the [(Cl4-cat)(PPr3)MoFe3S4(BH4)2]2(Bu4N)4 double-fused cubane. Inorganic Chemistry. 43: 6508-10. PMID 15476337 DOI: 10.1021/ic049275w  0.52
2004 Koutmos M, Coucouvanis D. Superclusters: a host-guest complex with a cyclic array of three bridged MoFe3S4 clusters. Angewandte Chemie (International Ed. in English). 43: 5023-5. PMID 15384123 DOI: 10.1002/anie.200460154  0.52
2001 Han J, Koutmos M, Ahmad SA, Coucouvanis D. Rational synthesis of high nuclearity Mo/Fe/S clusters: the reductive coupling approach in the convenient synthesis of (Cl(4)-cat)(2)Mo(2)Fe(6)S(8)(PR(3))(6) [R = Et, (n)Pr, (n)Bu] and the new [(Cl(4)-cat)(2)Mo(2)Fe(2)S(3)O(PEt(3))(3)Cl]-1/2(Fe(PEt(3))(2)(MeCN)(4)) and (Cl(4)-cat)(2)Mo(2)Fe(3)S(5)(PEt(3))(5) clusters. Inorganic Chemistry. 40: 5985-99. PMID 11681915 DOI: 10.1021/ic0104914  0.52
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