Sung H. Hwang, Ph.D. - Publications

Affiliations: 
2004 University of California, Davis, Davis, CA 
Area:
Combinatorial chemistry, heterocyclic chemistry, understanding reaction mechanisms, solid phase organic synthesis, polymer chemistry, organic synthesis, reaction methodology, and structure elucidation

111 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Ahn KC, Ranganathan A, Bever CR, Hwang SH, Holland EB, Morisseau K, Pessah IN, Hammock BD, Gee SJ. Detection of the Antimicrobial Triclosan in Environmental Samples by Immunoassay. Environmental Science & Technology. PMID 26937944 DOI: 10.1021/acs.est.5b05357  0.92
2015 Lee WK, Yoon H, Jung DW, Hwang SH, Park KS. Ballistocardiogram of baby during sleep. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2015: 7167-7170. PMID 26737945 DOI: 10.1109/EMBC.2015.7320045  0.4
2015 Liao J, Hwang SH, Li H, Yang Y, Yang J, Wecksler AT, Liu JY, Hammock BD, Yang GY. Inhibition of mutant Kras(G12D) -initiated murine pancreatic carcinoma growth by a dual c-Raf and soluble epoxide hydrolase inhibitor t-CUPM. Cancer Letters. PMID 26683769 DOI: 10.1016/j.canlet.2015.11.042  0.92
2015 Tu C, Gao D, Li XF, Li CY, Li RS, Zhao YL, Li N, Jia GL, Pang JY, Cui HR, Ma ZJ, Xiao XH, Wang JB. Inflammatory stress potentiates emodin-induced liver injury in rats. Frontiers in Pharmacology. 6: 233. PMID 26557087 DOI: 10.3389/fphar.2015.00233  0.92
2015 Liu JY, Tsai HJ, Morisseau C, Lango J, Hwang SH, Watanabe T, Kim IH, Hammock BD. In vitro and in vivo metabolism of N-adamantyl substituted urea-based soluble epoxide hydrolase inhibitors. Biochemical Pharmacology. PMID 26494425 DOI: 10.1016/j.bcp.2015.10.013  0.92
2015 Cho HK, Park IJ, Jeong YM, Lee YJ, Hwang SH. Can perioperative acupuncture reduce the pain and vomiting experienced after tonsillectomy? A meta-analysis. The Laryngoscope. PMID 26484723 DOI: 10.1002/lary.25721  0.36
2015 Hwang SH, Seo S, Yoon HN, Jung DW, Baek HJ, Cho J, Choi JW, Lee YJ, Jeong DU, Park KS. Sleep Period Time Estimation Based on Electrodermal Activity. Ieee Journal of Biomedical and Health Informatics. PMID 26469790 DOI: 10.1109/JBHI.2015.2490480  0.4
2015 Lee BH, Choi SH, Kim HJ, Jung SW, Kim H, Shin HC, Lee JH, Hwang SH, Kim HC, Nah SY. Preparation of a Monoclonal Antibody against Gintonin and Its Use in an Enzyme Immunoassay. Biological & Pharmaceutical Bulletin. 38: 1631-7. PMID 26424022 DOI: 10.1248/bpb.b15-00171  0.92
2015 Hwang SH, Cho HK, Park SH, Lee W, Lee HJ, Lee DC, Park SH, Lim MH, Back SA, Yun BG, Sun DI, Kang JM, Kim SW. Characteristics of Human Turbinate-Derived Mesenchymal Stem Cells Are Not Affected by Allergic Condition of Donor. Plos One. 10: e0138041. PMID 26376485 DOI: 10.1371/journal.pone.0138041  0.4
2015 Kim HJ, Shin EJ, Lee BH, Choi SH, Jung SW, Cho IH, Hwang SH, Kim JY, Han JS, Chung C, Jang CG, Rhim H, Kim HC, Nah SY. Oral Administration of Gintonin Attenuates Cholinergic Impairments by Scopolamine, Amyloid-β Protein, and Mouse Model of Alzheimer's Disease. Molecules and Cells. PMID 26255830 DOI: 10.14348/molcells.2015.0116  0.92
2015 Cho HK, Jeong YM, Lee HS, Lee YJ, Hwang SH. Efficacy of endonasal phototherapy for relieving the symptoms of allergic rhinitis: Meta-analysis. American Journal of Rhinology & Allergy. 29: 283-91. PMID 26163248 DOI: 10.2500/ajra.2015.29.4190  0.36
2015 Ostermann AI, Herbers J, Willenberg I, Chen R, Hwang SH, Greite R, Morisseau C, Gueler F, Hammock BD, Schebb NH. Oral treatment of rodents with soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU): Resulting drug levels and modulation of oxylipin pattern. Prostaglandins & Other Lipid Mediators. PMID 26117215 DOI: 10.1016/j.prostaglandins.2015.06.005  0.92
2015 Hwang SH, Han CM, Yoon HN, Jung DW, Lee YJ, Jeong DU, Park KS. Polyvinylidene fluoride sensor-based method for unconstrained snoring detection. Physiological Measurement. 36: 1399-1414. PMID 26012381 DOI: 10.1088/0967-3334/36/7/1399  0.4
2015 Lee HJ, Hwang SH, Yoon HN, Lee WK, Park KS. Heart Rate Variability Monitoring during Sleep Based on Capacitively Coupled Textile Electrodes on a Bed. Sensors (Basel, Switzerland). 15: 11295-311. PMID 26007716 DOI: 10.3390/s150511295  0.4
2015 Cho HK, Jeong YM, Lee HS, Lee YJ, Hwang SH. Effects of honey on oral mucositis in patients with head and neck Cancer: A meta-analysis. The Laryngoscope. PMID 25778825 DOI: 10.1002/lary.25233  0.36
2015 López-Vicario C, Alcaraz-Quiles J, García-Alonso V, Rius B, Hwang SH, Titos E, Lopategi A, Hammock BD, Arroyo V, Clària J. Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: role for omega-3 epoxides. Proceedings of the National Academy of Sciences of the United States of America. 112: 536-41. PMID 25550510 DOI: 10.1073/pnas.1422590112  0.92
2015 Hwang SH, Lee BH, Choi SH, Kim HJ, Jung SW, Kim HS, Shin HC, Park HJ, Park KH, Lee MK, Nah SY. Gintonin, a novel ginseng-derived lysophosphatidic acid receptor ligand, stimulates neurotransmitter release. Neuroscience Letters. 584: 356-61. PMID 25445364 DOI: 10.1016/j.neulet.2014.11.007  0.92
2015 Wecksler AT, Hwang SH, Liu JY, Wettersten HI, Morisseau C, Wu J, Weiss RH, Hammock BD. Biological evaluation of a novel sorafenib analogue, t-CUPM. Cancer Chemotherapy and Pharmacology. 75: 161-71. PMID 25413440 DOI: 10.1007/s00280-014-2626-2  0.92
2015 Kim J, Yoon SP, Toews ML, Imig JD, Hwang SH, Hammock BD, Padanilam BJ. Pharmacological inhibition of soluble epoxide hydrolase prevents renal interstitial fibrogenesis in obstructive nephropathy. American Journal of Physiology. Renal Physiology. 308: F131-9. PMID 25377915 DOI: 10.1152/ajprenal.00531.2014  0.92
2015 Yang J, Bratt J, Franzi L, Liu JY, Zhang G, Zeki AA, Vogel CF, Williams K, Dong H, Lin Y, Hwang SH, Kenyon NJ, Hammock BD. Soluble epoxide hydrolase inhibitor attenuates inflammation and airway hyperresponsiveness in mice. American Journal of Respiratory Cell and Molecular Biology. 52: 46-55. PMID 24922186 DOI: 10.1165/rcmb.2013-0440OC  0.92
2015 Kim HJ, Lee BH, Choi SH, Jung SW, Kim HS, Lee JH, Hwang SH, Pyo MK, Kim HC, Nah SY. Differential effects of quercetin glycosides on GABAC receptor channel activity. Archives of Pharmacal Research. 38: 108-14. PMID 24895146 DOI: 10.1007/s12272-014-0409-2  0.92
2015 Kim H, Lee BH, Choi SH, Kim HJ, Jung SW, Hwang SH, Rhim H, Kim HC, Cho IH, Nah SY. Gintonin stimulates gliotransmitter release in cortical primary astrocytes Neuroscience Letters. 603: 19-24. DOI: 10.1016/j.neulet.2015.07.012  0.92
2015 Hwang SH, Lee BH, Choi SH, Kim HJ, Won KJ, Lee HM, Rhim H, Kim HC, Nah SY. Effects of gintonin on the proliferation, migration, and tube formation of human umbilical-vein endothelial cells: Involvement of lysophosphatidic-acid receptors and vascular-endothelial-growth-factor signaling Journal of Ginseng Research. DOI: 10.1016/j.jgr.2015.10.002  0.92
2015 Choi SH, Jung SW, Kim HS, Kim HJ, Lee BH, Kim JY, Kim JH, Hwang SH, Rhim H, Kim HC, Nah SY. A brief method for preparation of gintonin-enriched fraction from ginseng Journal of Ginseng Research. 39: 398-405. DOI: 10.1016/j.jgr.2015.05.002  0.92
2015 Jung SW, Kim HJ, Lee BH, Choi SH, Kim HS, Choi YK, Kim JY, Kim ES, Hwang SH, Lim KY, Kim HC, Jang M, Park SK, Cho IH, Nah SY. Effects of Korean Red Ginseng extract on busulfan-induced dysfunction of the male reproductive system Journal of Ginseng Research. 39: 243-249. DOI: 10.1016/j.jgr.2015.01.002  0.92
2014 Hwang SH, Song JN, Jeong YM, Lee YJ, Kang JM. The efficacy of honey for ameliorating pain after tonsillectomy: a meta-analysis. European Archives of Oto-Rhino-Laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (Eufos) : Affiliated With the German Society For Oto-Rhino-Laryngology - Head and Neck Surgery. PMID 25524642 DOI: 10.1007/s00405-014-3433-4  0.36
2014 Choi SH, Lee BH, Kim HJ, Jung SW, Kim HS, Shin HC, Lee JH, Kim HC, Rhim H, Hwang SH, Ha TS, Kim HJ, Cho H, Nah SY. Ginseng gintonin activates the human cardiac delayed rectifier K+ channel: involvement of Ca2+/calmodulin binding sites. Molecules and Cells. 37: 656-63. PMID 25234465 DOI: 10.14348/molcells.2014.0087  0.92
2014 Park JH, Lee HJ, Kim SR, Song GW, Lee SK, Park SY, Kim KC, Hwang SH, Park JS. Etanercept for steroid-refractory acute graft versus host disease following allogeneic hematopoietic stem cell transplantation. The Korean Journal of Internal Medicine. 29: 630-6. PMID 25228839 DOI: 10.3904/kjim.2014.29.5.630  0.4
2014 Sporková A, Jíchová S, Husková Z, Kopkan L, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Kompanowska-Jezierska E, Sadowski J, Kramer HJ, Cervenka L. Different mechanisms of acute versus long-term antihypertensive effects of soluble epoxide hydrolase inhibition: studies in Cyp1a1-Ren-2 transgenic rats. Clinical and Experimental Pharmacology & Physiology. 41: 1003-13. PMID 25224811 DOI: 10.1111/1440-1681.12310  0.92
2014 Lee KS, Liu JY, Wagner KM, Pakhomova S, Dong H, Morisseau C, Fu SH, Yang J, Wang P, Ulu A, Mate CA, Nguyen LV, Hwang SH, Edin ML, Mara AA, et al. Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy. Journal of Medicinal Chemistry. 57: 7016-30. PMID 25079952 DOI: 10.1021/jm500694p  0.92
2014 Zhang G, Panigrahy D, Hwang SH, Yang J, Mahakian LM, Wettersten HI, Liu JY, Wang Y, Ingham ES, Tam S, Kieran MW, Weiss RH, Ferrara KW, Hammock BD. Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis. Proceedings of the National Academy of Sciences of the United States of America. 111: 11127-32. PMID 25024195 DOI: 10.1073/pnas.1410432111  0.92
2014 Gupta R, Dong Y, Solomon PD, Wettersten HI, Cheng CJ, Min JN, Henson J, Dogra SK, Hwang SH, Hammock BD, Zhu LJ, Reddel RR, Saltzman WM, Weiss RH, Chang S, et al. Synergistic tumor suppression by combined inhibition of telomerase and CDKN1A. Proceedings of the National Academy of Sciences of the United States of America. 111: E3062-71. PMID 25024194 DOI: 10.1073/pnas.1411370111  0.92
2014 Sarnpitak P, Mujumdar P, Morisseau C, Hwang SH, Hammock B, Iurchenko V, Zozulya S, Gavalas A, Geronikaki A, Ivanenkov Y, Krasavin M. Potent, orally available, selective COX-2 inhibitors based on 2-imidazoline core. European Journal of Medicinal Chemistry. 84: 160-72. PMID 25016374 DOI: 10.1016/j.ejmech.2014.07.023  0.92
2014 Zhao C, Hwang SH, Buchholz BA, Carpenter TS, Lightstone FC, Lightstone F, Yang J, Hammock BD, Casida JE. GABAA receptor target of tetramethylenedisulfotetramine. Proceedings of the National Academy of Sciences of the United States of America. 111: 8607-12. PMID 24912155 DOI: 10.1073/pnas.1407379111  0.92
2014 Shrestha A, Krishnamurthy PT, Thomas P, Hammock BD, Hwang SH. Soluble epoxide hydrolase inhibitor, t-TUCB, protects against myocardial ischaemic injury in rats. The Journal of Pharmacy and Pharmacology. 66: 1251-8. PMID 24697323 DOI: 10.1111/jphp.12251  0.92
2014 Lee BH, Hwang SH, Choi SH, Kim HJ, Jung SW, Kim HS, Lee JH, Kim HC, Rhim H, Nah SY. Resveratrol inhibits glycine receptor-mediated ion currents. Biological & Pharmaceutical Bulletin. 37: 576-80. PMID 24694604 DOI: DN/JST.JSTAGE/bpb/b13-00808  0.92
2014 Sun D, Cuevas AJ, Gotlinger K, Hwang SH, Hammock BD, Schwartzman ML, Huang A. Soluble epoxide hydrolase-dependent regulation of myogenic response and blood pressure. American Journal of Physiology. Heart and Circulatory Physiology. 306: H1146-53. PMID 24561863 DOI: 10.1152/ajpheart.00920.2013  0.92
2014 Wecksler AT, Hwang SH, Wettersten HI, Gilda JE, Patton A, Leon LJ, Carraway KL, Gomes AV, Baar K, Weiss RH, Hammock BD. Novel sorafenib-based structural analogues: in-vitro anticancer evaluation of t-MTUCB and t-AUCMB. Anti-Cancer Drugs. 25: 433-46. PMID 24525589 DOI: 10.1097/CAD.0000000000000079  0.92
2014 Kujal P, ?ertíková Chábová V, Škaroupková P, Husková Z, Vernerová Z, Kramer HJ, Walkowska A, Kompanowska-Jezierska E, Sadowski J, Kitada K, Nishiyama A, Hwang SH, Hammock BD, Imig JD, ?ervenka L. Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats. Clinical and Experimental Pharmacology & Physiology. 41: 227-37. PMID 24471737 DOI: 10.1111/1440-1681.12204  0.92
2014 Zhao C, Hwang SH, Buchholz BA, Carpenter TS, Lightstone F, Yang J, Hammock BD, Casida JE. GABAA receptor target of tetramethylenedisulfotetramine (Proceedings of the National Academy of Sciences of the United States of America (2014) 111 (8607-8612) DOI: 10.1073/pnas.1407379111) Proceedings of the National Academy of Sciences of the United States of America. 111: 11223. DOI: 10.1073/pnas.1412593111  0.92
2013 Inceoglu B, Zolkowska D, Yoo HJ, Wagner KM, Yang J, Hackett E, Hwang SH, Lee KS, Rogawski MA, Morisseau C, Hammock BD. Epoxy fatty acids and inhibition of the soluble epoxide hydrolase selectively modulate GABA mediated neurotransmission to delay onset of seizures. Plos One. 8: e80922. PMID 24349022 DOI: 10.1371/journal.pone.0080922  0.92
2013 Choi SH, Lee BH, Kim HJ, Jung SW, Hwang SH, Nah SY. Differential effects of ginsenoside metabolites on slowly activating delayed rectifier K(+) and KCNQ1 K(+) channel currents. Journal of Ginseng Research. 37: 324-31. PMID 24198658 DOI: 10.5142/jgr.2013.37.324  0.92
2013 Shaik JS, Ahmad M, Li W, Rose ME, Foley LM, Hitchens TK, Graham SH, Hwang SH, Hammock BD, Poloyac SM. Soluble epoxide hydrolase inhibitor trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is neuroprotective in rat model of ischemic stroke. American Journal of Physiology. Heart and Circulatory Physiology. 305: H1605-13. PMID 24043255 DOI: 10.1152/ajpheart.00471.2013  0.92
2013 Choi SH, Lee BH, Kim HJ, Hwang SH, Lee SM, Nah SY. Activation of lysophosphatidic Acid receptor is coupled to enhancement of ca(2+)-activated potassium channel currents. The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology. 17: 223-8. PMID 23776399 DOI: 10.4196/kjpp.2013.17.3.223  0.92
2013 Lee JH, Choi SH, Lee BH, Hwang SH, Kim HJ, Rhee J, Chung C, Nah SY. Activation of lysophosphatidic acid receptor by gintonin inhibits Kv1.2 channel activity: involvement of tyrosine kinase and receptor protein tyrosine phosphatase α. Neuroscience Letters. 548: 143-8. PMID 23769686 DOI: 10.1016/j.neulet.2013.05.048  0.92
2013 Hwang SH, Wecksler AT, Zhang G, Morisseau C, Nguyen LV, Fu SH, Hammock BD. Synthesis and biological evaluation of sorafenib- and regorafenib-like sEH inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 3732-7. PMID 23726028 DOI: 10.1016/j.bmcl.2013.05.011  0.92
2013 Morisseau C, Pakhomova S, Hwang SH, Newcomer ME, Hammock BD. Inhibition of soluble epoxide hydrolase by fulvestrant and sulfoxides. Bioorganic & Medicinal Chemistry Letters. 23: 3818-21. PMID 23684894 DOI: 10.1016/j.bmcl.2013.04.083  0.92
2013 Choi SH, Lee BH, Hwang SH, Kim HJ, Lee SM, Kim HC, Rhim HW, Nah SY. Molecular mechanisms of large-conductance ca (2+) -activated potassium channel activation by ginseng gintonin. Evidence-Based Complementary and Alternative Medicine : Ecam. 2013: 323709. PMID 23662129 DOI: 10.1155/2013/323709  0.92
2013 Poli G, Corda E, Martino PA, Dall'ara P, Bareggi SR, Bondiolotti G, Iulini B, Mazza M, Casalone C, Hwang SH, Hammock BD, Inceoglu B. Therapeutic activity of inhibition of the soluble epoxide hydrolase in a mouse model of scrapie. Life Sciences. 92: 1145-50. PMID 23651659 DOI: 10.1016/j.lfs.2013.04.014  0.92
2013 Lee BH, Choi SH, Hwang SH, Kim HJ, Lee SM, Kim HC, Rhim H, Nah SY. Effects of ginsenoside Rg3 on α9α10 nicotinic acetylcholine receptor-mediated ion currents. Biological & Pharmaceutical Bulletin. 36: 812-8. PMID 23649337 DOI: DN/JST.JSTAGE/bpb/b12-01009  0.92
2013 Lee BH, Choi SH, Hwang SH, Kim HJ, Lee JH, Nah SY. Resveratrol Inhibits GABAC ρ Receptor-Mediated Ion Currents Expressed in Xenopus Oocytes. The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology. 17: 175-80. PMID 23626481 DOI: 10.4196/kjpp.2013.17.2.175  0.92
2013 Lee BH, Hwang SH, Choi SH, Kim HJ, Lee JH, Lee SM, Ahn YG, Nah SY. Inhibitory Effects of Ginsenoside Metabolites, Compound K and Protopanaxatriol, on GABAC Receptor-Mediated Ion Currents. The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology. 17: 127-32. PMID 23626474 DOI: 10.4196/kjpp.2013.17.2.127  0.92
2013 Zhang G, Panigrahy D, Mahakian LM, Yang J, Liu JY, Stephen Lee KS, Wettersten HI, Ulu A, Hu X, Tam S, Hwang SH, Ingham ES, Kieran MW, Weiss RH, Ferrara KW, et al. Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis. Proceedings of the National Academy of Sciences of the United States of America. 110: 6530-5. PMID 23553837 DOI: 10.1073/pnas.1304321110  0.92
2013 Sirish P, Li N, Liu JY, Lee KS, Hwang SH, Qiu H, Zhao C, Ma SM, López JE, Hammock BD, Chiamvimonvat N. Unique mechanistic insights into the beneficial effects of soluble epoxide hydrolase inhibitors in the prevention of cardiac fibrosis. Proceedings of the National Academy of Sciences of the United States of America. 110: 5618-23. PMID 23493561 DOI: 10.1073/pnas.1221972110  0.92
2013 Choi SH, Kim HJ, Kim BR, Shin TJ, Hwang SH, Lee BH, Lee SM, Rhim H, Nah SY. Gintonin, a ginseng-derived lysophosphatidic acid receptor ligand, potentiates ATP-gated P2X₁ receptor channel currents. Molecules and Cells. 35: 142-50. PMID 23456336 DOI: 10.1007/s10059-013-2293-x  0.92
2013 Hwang SH, Wecksler AT, Wagner K, Hammock BD. Rationally designed multitarget agents against inflammation and pain. Current Medicinal Chemistry. 20: 1783-99. PMID 23410172 DOI: 10.2174/0929867311320130013  0.92
2013 Honetschlägerová Z, Kitada K, Husková Z, Sporková A, Kopkan L, Bürgelová M, Varcabová Š, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Kramer HJ, Kujal P, Vernerová Z, ?ervenka L. Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME. Journal of Hypertension. 31: 321-32. PMID 23307303 DOI: 10.1097/HJH.0b013e32835b50aa  0.92
2013 Wettersten HI, Hee Hwang S, Li C, Shiu EY, Wecksler AT, Hammock BD, Weiss RH. A novel p21 attenuator which is structurally related to sorafenib. Cancer Biology & Therapy. 14: 278-85. PMID 23298903 DOI: 10.4161/cbt.23374  0.92
2013 Liu JY, Lin YP, Qiu H, Morisseau C, Rose TE, Hwang SH, Chiamvimonvat N, Hammock BD. Substituted phenyl groups improve the pharmacokinetic profile and anti-inflammatory effect of urea-based soluble epoxide hydrolase inhibitors in murine models. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 48: 619-27. PMID 23291046 DOI: 10.1016/j.ejps.2012.12.013  0.92
2013 Wagner K, Inceoglu B, Dong H, Yang J, Hwang SH, Jones P, Morisseau C, Hammock BD. Comparative efficacy of 3 soluble epoxide hydrolase inhibitors in rat neuropathic and inflammatory pain models. European Journal of Pharmacology. 700: 93-101. PMID 23276668 DOI: 10.1016/j.ejphar.2012.12.015  0.92
2013 Lee KSS, Morisseau C, Yang J, Wang P, Hwang SH, Hammock BD. Förster resonance energy transfer competitive displacement assay for human soluble epoxide hydrolase Analytical Biochemistry. 434: 259-268. PMID 23219719 DOI: 10.1016/j.ab.2012.11.015  0.92
2013 Hwang SH, Lee BH, Kim HJ, Cho HJ, Shin HC, Im KS, Choi SH, Shin TJ, Lee SM, Nam SW, Kim HC, Rhim H, Nah SY. Suppression of metastasis of intravenously-inoculated B16/F10 melanoma cells by the novel ginseng-derived ingredient, gintonin: involvement of autotaxin inhibition. International Journal of Oncology. 42: 317-26. PMID 23174888 DOI: 10.3892/ijo.2012.1709  0.92
2013 Kundu S, Roome T, Bhattacharjee A, Carnevale KA, Yakubenko VP, Zhang R, Hwang SH, Hammock BD, Cathcart MK. Metabolic products of soluble epoxide hydrolase are essential for monocyte chemotaxis to MCP-1 in vitro and in vivo. Journal of Lipid Research. 54: 436-47. PMID 23160182 DOI: 10.1194/jlr.M031914  0.92
2013 Varcabova S, Huskova Z, Kramer HJ, Hwang SH, Hammock BD, Imig JD, Kitada K, Cervenka L. Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system. Clinical and Experimental Pharmacology & Physiology. 40: 273-81. PMID 23039246 DOI: 10.1111/1440-1681.12018  0.92
2012 Shin TJ, Kim HJ, Kwon BJ, Choi SH, Kim HB, Hwang SH, Lee BH, Lee SM, Zukin RS, Park JH, Kim HC, Rhim H, Lee JH, Nah SY. Gintonin, a ginseng-derived novel ingredient, evokes long-term potentiation through N-methyl-D-aspartic acid receptor activation: involvement of LPA receptors. Molecules and Cells. 34: 563-72. PMID 23161173 DOI: 10.1007/s10059-012-0254-4  0.92
2012 Kopkan L, Husková Z, Sporková A, Varcabová Š, Honetschlägerová Z, Hwang SH, Tsai HJ, Hammock BD, Imig JD, Kramer HJ, Bürgelová M, Vojtíšková A, Kujal P, Vernerová Z, Červenka L. Soluble epoxide hydrolase inhibition exhibits antihypertensive actions independently of nitric oxide in mice with renovascular hypertension. Kidney & Blood Pressure Research. 35: 595-607. PMID 22948718 DOI: 10.1159/000339883  0.92
2012 Inceoglu B, Wagner KM, Yang J, Bettaieb A, Schebb NH, Hwang SH, Morisseau C, Haj FG, Hammock BD. Acute augmentation of epoxygenated fatty acid levels rapidly reduces pain-related behavior in a rat model of type I diabetes. Proceedings of the National Academy of Sciences of the United States of America. 109: 11390-5. PMID 22733772 DOI: 10.1073/pnas.1208708109  0.92
2012 Lee BH, Hwang SH, Choi SH, Shin TJ, Kang J, Kim HJ, Kim HC, Lee JH, Nah SY. Inhibitory effects of dextrorotatory morphinans on the human 5-HT(3A) receptor expressed in Xenopus oocytes: Involvement of the N-terminal domain of the 5-HT(3A) receptor. European Journal of Pharmacology. 686: 41-9. PMID 22575521 DOI: 10.1016/j.ejphar.2012.04.047  0.92
2012 Shin TJ, Hwang SH, Choi SH, Lee BH, Kang J, Kim HJ, Zukin RS, Rhim H, Nah SY. Effects of protopanaxatriol-ginsenoside metabolites on rat N-methyl-d-aspartic Acid receptor-mediated ion currents. The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology. 16: 113-8. PMID 22563256 DOI: 10.4196/kjpp.2012.16.2.113  0.92
2012 Hwang SH, Shin EJ, Shin TJ, Lee BH, Choi SH, Kang J, Kim HJ, Kwon SH, Jang CG, Lee JH, Kim HC, Nah SY. Gintonin, a ginseng-derived lysophosphatidic acid receptor ligand, attenuates Alzheimer's disease-related neuropathies: involvement of non-amyloidogenic processing. Journal of Alzheimer's Disease : Jad. 31: 207-23. PMID 22543851 DOI: 10.3233/JAD-2012-120439  0.92
2012 Neckár J, Kopkan L, Husková Z, Kolář F, Papoušek F, Kramer HJ, Hwang SH, Hammock BD, Imig JD, Malý J, Netuka I, Ošťádal B, Červenka L. Inhibition of soluble epoxide hydrolase by cis-4-[4-(3-adamantan-I-ylureido)cyclohexyloxy] benzoic acid exhibits antihypertensive and cardioprotective actions in transgenic rats with angiotensin II-dependent hypertension Clinical Science. 122: 513-525. PMID 22324471 DOI: 10.1042/CS20110622  0.92
2012 Hwang SH, Shin TJ, Choi SH, Cho HJ, Lee BH, Pyo MK, Lee JH, Kang J, Kim HJ, Park CW, Shin HC, Nah SY. Gintonin, newly identified compounds from ginseng, is novel lysophosphatidic acids-protein complexes and activates G protein-coupled lysophosphatidic acid receptors with high affinity. Molecules and Cells. 33: 151-62. PMID 22286231 DOI: 10.1007/s10059-012-2216-z  0.92
2012 Iyer A, Kauter K, Alam MA, Hwang SH, Morisseau C, Hammock BD, Brown L. Pharmacological inhibition of soluble epoxide hydrolase ameliorates diet-induced metabolic syndrome in rats. Experimental Diabetes Research. 2012: 758614. PMID 22007192 DOI: 10.1155/2012/758614  0.92
2012 Lee DG, Cho HJ, Yi H, Cho SM, Jo K, Park JA, Lee BH, Hwang SH, Jeong SM, Nah SY, Shin HC. Functional expression and characterization in Xenopus laevis oocytes of the ABCG2 transporter derived from A549 human lung adenocarcinoma cells. Oncology Reports. 27: 499-503. PMID 21971989 DOI: 10.3892/or.2011.1490  0.92
2012 Ulu A, Appt S, Morisseau C, Hwang SH, Jones PD, Rose TE, Dong H, Lango J, Yang J, Tsai HJ, Miyabe C, Fortenbach C, Adams MR, Hammock BD. Pharmacokinetics and in vivo potency of soluble epoxide hydrolase inhibitors in cynomolgus monkeys. British Journal of Pharmacology. 165: 1401-12. PMID 21880036 DOI: 10.1111/j.1476-5381.2011.01641.x  0.92
2012 Lee BH, Choi SH, Shin TJ, Hwang SH, Kang J, Kim HJ, Kim BJ, Nah SY. Effects of ginsenoside metabolites on GABA A receptor-mediated ion currents Journal of Ginseng Research. 36: 55-60. DOI: org/10.5142/jgr.2012.36.1.55  0.92
2011 Choi SH, Shin TJ, Lee BH, Hwang SH, Kang J, Kim HJ, Park CW, Nah SY. An edible gintonin preparation from ginseng. Journal of Ginseng Research. 35: 471-8. PMID 23717094 DOI: 10.5142/jgr.2011.35.4.471  0.92
2011 Pyo MK, Choi SH, Shin TJ, Hwang SH, Lee BH, Kang J, Kim HJ, Lee SH, Nah SY. A simple method for the preparation of crude gintonin from ginseng root, stem, and leaf. Journal of Ginseng Research. 35: 209-18. PMID 23717063 DOI: 10.5142/jgr.2011.35.2.209  0.92
2011 Choi SH, Shin TJ, Hwang SH, Lee BH, Kang J, Kim HJ, Oh JW, Bae CS, Lee SH, Nah SY. Differential effects of ginsenoside metabolites on HERG k channel currents. Journal of Ginseng Research. 35: 191-9. PMID 23717061 DOI: 10.5142/jgr.2011.35.2.191  0.92
2011 Lee BH, Shin TJ, Hwang SH, Choi SH, Kang J, Kim HJ, Park CW, Lee SH, Nah SY. Inhibitory Effects of Quercetin on Muscle-type of Nicotinic Acetylcholine Receptor-Mediated Ion Currents Expressed in Xenopus Oocytes. The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology. 15: 195-201. PMID 21994477 DOI: 10.4196/kjpp.2011.15.4.195  0.92
2011 Inoue H, Hwang SH, Wecksler AT, Hammock BD, Weiss RH. Sorafenib attenuates p21 in kidney cancer cells and augments cell death in combination with DNA-damaging chemotherapy. Cancer Biology & Therapy. 12: 827-36. PMID 21878748 DOI: 10.4161/cbt.12.9.17680  0.92
2011 Liu JY, Qiu H, Morisseau C, Hwang SH, Tsai HJ, Ulu A, Chiamvimonvat N, Hammock BD. Inhibition of soluble epoxide hydrolase contributes to the anti-inflammatory effect of antimicrobial triclocarban in a murine model. Toxicology and Applied Pharmacology. 255: 200-6. PMID 21741984 DOI: 10.1016/j.taap.2011.06.017  0.92
2011 Honetschlägerová Z, Sporková A, Kopkan L, Husková Z, Hwang SH, Hammock BD, Imig JD, Kramer HJ, Kujal P, Vernerová Z, Chábová VC, Tesař V, Cervenka L. Inhibition of soluble epoxide hydrolase improves the impaired pressure-natriuresis relationship and attenuates the development of hypertension and hypertension-associated end-organ damage in Cyp1a1-Ren-2 transgenic rats. Journal of Hypertension. 29: 1590-601. PMID 21720266 DOI: 10.1097/HJH.0b013e328349062f  0.92
2011 Liu X, Li C, Gebremedhin D, Hwang SH, Hammock BD, Falck JR, Roman RJ, Harder DR, Koehler RC. Epoxyeicosatrienoic acid-dependent cerebral vasodilation evoked by metabotropic glutamate receptor activation in vivo American Journal of Physiology - Heart and Circulatory Physiology. 301: H373-H381. PMID 21602473 DOI: 10.1152/ajpheart.00745.2010  0.92
2011 Choi SH, Shin TJ, Hwang SH, Lee BH, Kang J, Kim HJ, Jo SH, Choe H, Nah SY. Ginsenoside Rg(3) decelerates hERG K(+) channel deactivation through Ser631 residue interaction. European Journal of Pharmacology. 663: 59-67. PMID 21586280 DOI: 10.1016/j.ejphar.2011.05.006  0.92
2011 Schebb NH, Huby M, Morisseau C, Hwang SH, Hammock BD. Development of an online SPE-LC-MS-based assay using endogenous substrate for investigation of soluble epoxide hydrolase (sEH) inhibitors Analytical and Bioanalytical Chemistry. 400: 1359-1366. PMID 21479549 DOI: 10.1007/s00216-011-4861-2  0.92
2011 Lee BH, Hwang SH, Choi SH, Shin TJ, Kang J, Lee SM, Nah SY. Resveratrol enhances 5-hydroxytryptamine type 3A receptor-mediated ion currents: the role of arginine 222 residue in pre-transmembrane domain I. Biological & Pharmaceutical Bulletin. 34: 523-7. PMID 21467640 DOI: JST.JSTAGE/bpb/34.523  0.92
2011 Lee BH, Hwang SH, Choi SH, Shin TJ, Kang J, Lee SM, Nah SY. Quercetin Inhibits α3β4 Nicotinic Acetylcholine Receptor-Mediated Ion Currents Expressed in Xenopus Oocytes. The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology. 15: 17-22. PMID 21461236 DOI: 10.4196/kjpp.2011.15.1.17  0.92
2011 Hwang SH, Wagner KM, Morisseau C, Liu JY, Dong H, Wecksler AT, Hammock BD. Synthesis and structure-activity relationship studies of urea-containing pyrazoles as dual inhibitors of cyclooxygenase-2 and soluble epoxide hydrolase. Journal of Medicinal Chemistry. 54: 3037-50. PMID 21434686 DOI: 10.1021/jm2001376  0.92
2011 Sporková A, Kopkan L, Varcabová S, Husková Z, Hwang SH, Hammock BD, Imig JD, Kramer HJ, Červenka L. Role of cytochrome P-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive rats American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 300: 1468-1475. PMID 21411763 DOI: 10.1152/ajpregu.00215.2010  0.92
2011 Choi SH, Shin TJ, Lee BH, Hwang SH, Lee SM, Lee BC, Park CS, Ha TS, Nah SY. Ginsenoside Rg3 enhances large conductance Ca 2+-activated potassium channel currents: A role of Tyr360 residue Molecules and Cells. 31: 133-140. PMID 21191818 DOI: 10.1007/s10059-011-0017-7  0.92
2011 Lee JH, Choi SH, Shin TJ, Lee BH, Hwang SH, Kim HC, Nah SY. Effect of dextromethorphan on human Kv1.3 channel activity: Involvement of C-type inactivation European Journal of Pharmacology. 651: 122-127. PMID 21114979 DOI: 10.1016/j.ejphar.2010.10.091  0.92
2011 Honetschlägerová Z, Z Husková Z, Vaňourková Z, Sporková A, Kramer HJ, Hwang SH, Tsai HJ, Hammock BD, Imig JD, Červenka L, Kopkan L. Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats with inducible hypertension. The Journal of Physiology. 589: 207-19. PMID 21078594 DOI: 10.1113/jphysiol.2010.199505  0.92
2011 Lee BH, Choi SH, Shin TJ, Pyo MK, Hwang SH, Lee SM, Paik HD, Kim HC, Nah SY. Effects of quercetin on α9α10 nicotinic acetylcholine receptor-mediated ion currents European Journal of Pharmacology. 650: 79-85. PMID 20950602 DOI: 10.1016/j.ejphar.2010.09.079  0.92
2011 Lee JH, Ahn JY, Shin TJ, Choi SH, Lee BH, Hwang SH, Kang J, Kim HJ, Park CW, Nah SY. Efects of minor ginsenosides, ginsenoside metabolites, and ginsenoside epimers on the growth of caenorhabditis elegans Journal of Ginseng Research. 35: 375-383.  0.92
2010 Shin TJ, Choi SH, Lee BH, Pyo MK, Hwang SH, Kim BR, Lee SM, Han YS, Lee JH, Park JH, Kim HC, Rhim H, Nah SY. Effects of quercetin on human α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-mediated ion currents. Biological & Pharmaceutical Bulletin. 33: 1615-9. PMID 20823584 DOI: JST.JSTAGE/bpb/33.1615  0.92
2010 Lee BH, Choi SH, Shin TJ, Pyo MK, Hwang SH, Kim BR, Lee SM, Lee JH, Kim HC, Park HY, Rhim H, Nah SY. Quercetin enhances human α7 nicotinic acetylcholine receptor-mediated ion current through interactions with Ca(2+) binding sites. Molecules and Cells. 30: 245-53. PMID 20803082 DOI: 10.1007/s10059-010-0117-9  0.92
2010 Jung O, Jansen F, Mieth A, Barbosa-Sicard E, Pliquett RU, Babelova A, Morisseau C, Hwang SH, Tsai C, Hammock BD, Schaefer L, Geisslinger G, Amann K, Brandes RP. Inhibition of the soluble epoxide hydrolase promotes albuminuria in mice with progressive renal disease. Plos One. 5: e11979. PMID 20694143 DOI: 10.1371/journal.pone.0011979  0.92
2010 Kim YM, Lee JK, Abd El-aty AM, Hwang SH, Lee JH, Lee SM. Efficacy of dog-appeasing pheromone (DAP) for ameliorating separation-related behavioral signs in hospitalized dogs Canadian Veterinary Journal. 51: 380-384. PMID 20592826  0.92
2010 Luo P, Chang HH, Zhou Y, Zhang S, Hwang SH, Morisseau C, Wang CY, Inscho EW, Hammock BD, Wang MH. Inhibition or deletion of soluble epoxide hydrolase prevents hyperglycemia, promotes insulin secretion, and reduces islet apoptosis. The Journal of Pharmacology and Experimental Therapeutics. 334: 430-8. PMID 20439437 DOI: 10.1124/jpet.110.167544  0.92
2010 Choi SH, Shin TJ, Lee BH, Chu DH, Choe H, Pyo MK, Hwang SH, Kim BR, Lee SM, Lee JH, Kim DH, Kim HC, Rhim HW, Nah SY. Ginsenoside Rg3 activates human KCNQ1 K+ channel currents through interacting with the K318 and V319 residues: a role of KCNE1 subunit. European Journal of Pharmacology. 637: 138-47. PMID 20399767 DOI: 10.1016/j.ejphar.2010.04.001  0.92
2010 Tsai HJ, Hwang SH, Morisseau C, Yang J, Jones PD, Kasagami T, Kim IH, Hammock BD. Pharmacokinetic screening of soluble epoxide hydrolase inhibitors in dogs. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 40: 222-38. PMID 20359531 DOI: 10.1016/j.ejps.2010.03.018  0.92
2010 Liu JY, Yang J, Inceoglu B, Qiu H, Ulu A, Hwang SH, Chiamvimonvat N, Hammock BD. Inhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine model. Biochemical Pharmacology. 79: 880-7. PMID 19896470 DOI: 10.1016/j.bcp.2009.10.025  0.92
2010 Chaudhary KR, Abukhashim M, Hwang SH, Hammock BD, Seubert JM. Inhibition of soluble epoxide hydrolase by trans-4- [4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid is protective against ischemia-reperfusion injury. Journal of Cardiovascular Pharmacology. 55: 67-73. PMID 19834332 DOI: 10.1097/FJC.0b013e3181c37d69  0.92
2009 Li N, Liu JY, Timofeyev V, Qiu H, Hwang SH, Tuteja D, Lu L, Yang J, Mochida H, Low R, Hammock BD, Chiamvimonvat N. Beneficial effects of soluble epoxide hydrolase inhibitors in myocardial infarction model: Insight gained using metabolomic approaches. Journal of Molecular and Cellular Cardiology. 47: 835-45. PMID 19716829 DOI: 10.1016/j.yjmcc.2009.08.017  0.92
2009 Choi SH, Lee JH, Pyo MK, Lee BH, Shin TJ, Hwang SH, Kim BR, Lee SM, Oh JW, Kim HC, Bae CS, Rhim H, Nah SY. Mutations Leu427, Asn428, and Leu431 residues within transmembrane domain-I-segment 6 attenuate ginsenoside-mediated L-type Ca2+ channel current inhibitions Biological and Pharmaceutical Bulletin. 32: 1224-1230. PMID 19571390 DOI: 10.1248/bpb.32.1224  0.92
2009 Lee BH, Choi SH, Pyo MK, Shin TJ, Hwang SH, Kim BR, Lee SM, Lee JH, Lee JH, Lee HS, Choe H, Han KH, Kim HC, Rhim H, Yong JH, et al. A role for Leu247 residue within transmembrane domain 2 in ginsenoside-mediated alpha7 nicotinic acetylcholine receptor regulation. Molecules and Cells. 27: 591-9. PMID 19466608 DOI: 10.1007/s10059-009-0073-4  0.92
2004 Hwang SH, Lehman A, Cong X, Olmstead MM, Lam KS, Lebrilla CB, Kurth MJ. OBOC small-molecule combinatorial library encoded by halogenated mass-tags. Organic Letters. 6: 3829-32. PMID 15469360 DOI: 10.1021/ol048408e  0.92
2004 Hwang SH, Olmstead MM, Kurth MJ. Solid-phase synthesis of an isoxazolinopyrrole library. Journal of Combinatorial Chemistry. 6: 142-8. PMID 14714998 DOI: 10.1021/cc034023w  0.92
2002 Hwang SH, Kurth MJ. Versatile "traceless" sulfone linker for SPOS: preparation of isoxazolinopyrrole 2-carboxylates. The Journal of Organic Chemistry. 67: 6564-7. PMID 12201785 DOI: 10.1021/jo016377k  0.92
2002 Kwon HJ, Smith WC, Scharon AJ, Hwang SH, Kurth MJ, Shen B. C-O bond formation by polyketide synthases. Science (New York, N.Y.). 297: 1327-30. PMID 12193782 DOI: 10.1126/science.1073175  0.92
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