James L. Edwards, Ph.D. - Publications

2006 University of Michigan, Ann Arbor, Ann Arbor, MI 
Nanoscale analytical techniques, chemical separations, mass spectrometry, microfluidics, neurochemistry, and islet biology

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Coulton JB, Edwards JL. Capillary flow-based sample preparation system for metabolomic analysis of mammalian cells in suspension. Analytical and Bioanalytical Chemistry. PMID 33665672 DOI: 10.1007/s00216-021-03204-y  0.64
2020 Kaplitz AS, Mostafa ME, Calvez SA, Edwards JL, Grinias JP. Two-Dimensional Separation Techniques Using Supercritical Fluid Chromatography. Journal of Separation Science. PMID 33090652 DOI: 10.1002/jssc.202000823  0.6
2020 Sanders KL, Edwards JL. Nano-liquid chromatography-mass spectrometry and recent applications in omics investigations. Analytical Methods : Advancing Methods and Applications. PMID 32901622 DOI: 10.1039/D0Ay01194K  0.44
2020 Goll JB, Li S, Edwards JL, Bosinger SE, Jensen TL, Wang Y, Hooper WF, Gelber CE, Sanders KL, Anderson EJ, Rouphael N, Natrajan MS, Johnson RA, Sanz P, Hoft D, et al. Transcriptomic and Metabolic Responses to a Live-Attenuated Vaccine. Vaccines. 8. PMID 32722194 DOI: 10.3390/Vaccines8030412  0.44
2020 Guan S, Armbruster M, Huang T, Edwards JL, Bythell BJ. Isomeric Differentiation and Acidic Metabolite Identification by Piperidine-based Tagging, LC-MS/MS, and Understanding of the Dissociation Chemistries. Analytical Chemistry. PMID 32466643 DOI: 10.1021/Acs.Analchem.0C01640  0.36
2019 Filla LA, Sanders KL, Coulton JB, Filla RT, Edwards JL. Determination of online quenching efficiency for an automated cellular microfluidic metabolomic platform using mass spectrometry based ATP degradation analysis. Analytical and Bioanalytical Chemistry. PMID 31372700 DOI: 10.1007/S00216-019-02018-3  0.64
2019 Huang T, Rabus JM, Bythell BJ, Edwards JL. Fragmentation of Multi-charged Derivatized Lysine Using Nanospray CID Tandem Mass Spectrometry. Journal of the American Society For Mass Spectrometry. PMID 30993635 DOI: 10.1007/S13361-019-02154-1  0.36
2018 Huang T, Armbruster MR, Coulton JB, Edwards JL. Chemical Tagging in Mass Spectrometry for Systems Biology. Analytical Chemistry. PMID 30392353 DOI: 10.1021/Acs.Analchem.8B04951  0.64
2018 Li L, Liu X, Sanders KL, Edwards JL, Ye J, Si F, Gao A, Huang L, Hsueh EC, Ford DA, Hoft DF, Peng G. TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy. Cell Metabolism. PMID 30344014 DOI: 10.1016/J.Cmet.2018.09.020  0.44
2018 Huang T, Armbruster M, Lee R, Hui DS, Edwards JL. Metabolomic analysis of mammalian cells and human tissue through one-pot two stage derivatizations using sheathless capillary electrophoresis-electrospray ionization-mass spectrometry. Journal of Chromatography. A. PMID 30005940 DOI: 10.1016/J.Chroma.2018.07.007  0.36
2018 Huang T, Toro M, Lee R, Hui DS, Edwards JL. Multi-functional derivatization of amine, hydroxyl, and carboxylate groups for metabolomic investigations of human tissue by electrospray ionization mass spectrometry. The Analyst. PMID 29915825 DOI: 10.1039/C8An00490K  0.36
2018 Filla RT, Schrell AM, Coulton JB, Edwards JL, Roper MG. Frequency-Modulated Continuous Flow Analysis Electrospray Ionization Mass Spectrometry (FM-CFA-ESI-MS) for Sample Multiplexing. Analytical Chemistry. PMID 29356503 DOI: 10.1021/Acs.Analchem.7B04669  0.64
2016 Filla LA, Sanders KL, Filla RT, Edwards JL. Automated sample preparation in a microfluidic culture device for cellular metabolomics. The Analyst. PMID 27118418 DOI: 10.1039/C6An00237D  1
2016 Filla LA, Edwards JL. Metabolomics in diabetic complications. Molecular Biosystems. PMID 26891794 DOI: 10.1039/C6Mb00014B  1
2015 Yuan W, Li S, Edwards JL. Extraction and Quantitation of Ketones and Aldehydes from Mammalian Cells using Fluorous Tagging and Capillary LC-MS. Analytical Chemistry. PMID 26114225 DOI: 10.1021/Acs.Analchem.5B01000  1
2015 Esch C, Hui DS, Lee R, Edwards JL. Quantitation of thiol metabolites from mammalian cells using fluorous tagging and HILIC-MS Analytical Methods. 7: 7164-7169. DOI: 10.1039/C5Ay00603A  1
2015 Filla LA, Edwards JL. Lab-on-a-chip cell culture for metabolomics European Pharmaceutical Review. 20: 15-20.  1
2014 Filla LA, Yuan W, Feldman EL, Li S, Edwards JL. Global metabolomic and isobaric tagging capillary liquid chromatography-tandem mass spectrometry approaches for uncovering pathway dysfunction in diabetic mouse aorta. Journal of Proteome Research. 13: 6121-34. PMID 25368974 DOI: 10.1021/Pr501030E  1
2013 Yuan W, Edwards JL, Li S. Global profiling of carbonyl metabolites with a photo-cleavable isobaric labeling affinity tag. Chemical Communications (Cambridge, England). 49: 11080-2. PMID 24141386 DOI: 10.1039/C3Cc45956J  1
2013 Yang S, Yuan W, Yang W, Zhou J, Harlan R, Edwards J, Li S, Zhang H. Glycan analysis by isobaric aldehyde reactive tags and mass spectrometry. Analytical Chemistry. 85: 8188-95. PMID 23895018 DOI: 10.1021/Ac401226D  1
2012 Chemnitz Galal W, Pan M, Giulian G, Yuan W, Li S, Edwards JL, Marino JP, Kelman Z, Hurwitz J. Formation of dAMP-glycerol and dAMP-Tris derivatives by Thermococcus kodakaraensis DNA primase. The Journal of Biological Chemistry. 287: 16220-9. PMID 22427647 DOI: 10.1074/Jbc.M111.338160  1
2012 Chen Z, Wang Q, Lin L, Tang Q, Edwards JL, Li S, Liu S. Comparative evaluation of two isobaric labeling tags, DiART and iTRAQ. Analytical Chemistry. 84: 2908-15. PMID 22404494 DOI: 10.1021/Ac203467Q  1
2012 Yuan W, Anderson KW, Li S, Edwards JL. Subsecond absolute quantitation of amine metabolites using isobaric tags for discovery of pathway activation in mammalian cells. Analytical Chemistry. 84: 2892-9. PMID 22401307 DOI: 10.1021/Ac203453T  1
2011 Yuan W, Zhang J, Li S, Edwards JL. Amine metabolomics of hyperglycemic endothelial cells using capillary LC-MS with isobaric tagging. Journal of Proteome Research. 10: 5242-50. PMID 21961526 DOI: 10.1021/Pr200815C  1
2011 Li Z, Pan M, Santangelo TJ, Chemnitz W, Yuan W, Edwards JL, Hurwitz J, Reeve JN, Kelman Z. A novel DNA nuclease is stimulated by association with the GINS complex Nucleic Acids Research. 39: 6114-6123. PMID 21459845 DOI: 10.1093/Nar/Gkr181  1
2011 Yuan W, Edwards JL. Thiol metabolomics of endothelial cells using capillary liquid chromatography mass spectrometry with isotope coded affinity tags. Journal of Chromatography. A. 1218: 2561-8. PMID 21420094 DOI: 10.1016/J.Chroma.2011.02.063  1
2010 Yuan W, Edwards JL. Capillary separations in metabolomics. Bioanalysis. 2: 953-63. PMID 21083226 DOI: 10.4155/bio.10.40  1
2010 Vincent AM, Edwards JL, McLean LL, Hong Y, Cerri F, Lopez I, Quattrini A, Feldman EL. Mitochondrial biogenesis and fission in axons in cell culture and animal models of diabetic neuropathy. Acta Neuropathologica. 120: 477-89. PMID 20473509 DOI: 10.1007/S00401-010-0697-7  1
2010 Lentz SI, Edwards JL, Backus C, McLean LL, Haines KM, Feldman EL. Mitochondrial DNA (mtDNA) biogenesis: visualization and duel incorporation of BrdU and EdU into newly synthesized mtDNA in vitro. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 58: 207-18. PMID 19875847 DOI: 10.1369/Jhc.2009.954701  1
2010 Edwards JL, Quattrini A, Lentz SI, Figueroa-Romero C, Cerri F, Backus C, Hong Y, Feldman EL. Diabetes regulates mitochondrial biogenesis and fission in mouse neurons. Diabetologia. 53: 160-9. PMID 19847394 DOI: 10.1007/S00125-009-1553-Y  1
2008 Edwards JL, Vincent AM, Cheng HT, Feldman EL. Diabetic neuropathy: mechanisms to management. Pharmacology & Therapeutics. 120: 1-34. PMID 18616962 DOI: 10.1016/J.Pharmthera.2008.05.005  1
2008 Vincent AM, Edwards JL, Sadidi M, Feldman EL. The antioxidant response as a drug target in diabetic neuropathy. Current Drug Targets. 9: 94-100. PMID 18220717 DOI: 10.2174/138945008783431754  1
2007 Edwards JL, Edwards RL, Reid KR, Kennedy RT. Effect of decreasing column inner diameter and use of off-line two-dimensional chromatography on metabolite detection in complex mixtures. Journal of Chromatography. A. 1172: 127-34. PMID 17961581 DOI: 10.1016/J.Chroma.2007.09.075  1
2007 Little AA, Edwards JL, Feldman EL. Diabetic neuropathies. Practical Neurology. 7: 82-92. PMID 17430872  1
2006 Leinninger GM, Edwards JL, Lipshaw MJ, Feldman EL. Mechanisms of disease: mitochondria as new therapeutic targets in diabetic neuropathy. Nature Clinical Practice. Neurology. 2: 620-8. PMID 17057749 DOI: 10.1038/Ncpneuro0320  1
2006 Edwards JL, Chisolm CN, Shackman JG, Kennedy RT. Negative mode sheathless capillary electrophoresis electrospray ionization-mass spectrometry for metabolite analysis of prokaryotes. Journal of Chromatography. A. 1106: 80-8. PMID 16443454 DOI: 10.1016/J.Chroma.2005.08.082  1
2005 Edwards JL, Kennedy RT. Metabolomic analysis of eukaryotic tissue and prokaryotes using negative mode MALDI time-of-flight mass spectrometry. Analytical Chemistry. 77: 2201-9. PMID 15801754 DOI: 10.1021/Ac048323R  1
2002 Shim JY, Welsh WJ, Cartier E, Edwards JL, Howlett AC. Molecular interaction of the antagonist N-(piperidin-1-yl)-5-(4-chlorophenyl)-1- (2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide with the CB1 cannabinoid receptor. Journal of Medicinal Chemistry. 45: 1447-59. PMID 11906286 DOI: 10.1021/Jm010267O  1
2001 Edwards J, Sprung R, Sprague R, Spence D. Chemiluminescence detection of ATP release from red blood cells upon passage through microbore tubing. The Analyst. 126: 1257-60. PMID 11534589 DOI: 10.1039/B100519G  1
2000 Edwards J, Patel A, Spence DM. Performance enhancement in flow reversal flow injection using on-capillary detection Analytica Chimica Acta. 417: 185-190. DOI: 10.1016/S0003-2670(00)00928-4  1
1999 Edwards JL, Bauman R, Spence DM. Air segmented continuous flow analysis in microbore tubing Analytica Chimica Acta. 401: 209-214. DOI: 10.1016/S0003-2670(99)00524-3  1
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