Lark J. Perez, Ph.D. - Publications

Affiliations: 
2009 Yale University, New Haven, CT 
Area:
Organic Chemistry, Medicinal Chemistry

16/55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Capilato JN, Pellegrinelli PJ, Bernard J, Schnorbus L, Philippi S, Mattiucci J, Hoy EP, Perez LJ. Acetyl nitrate mediated conversion of methyl ketones to diverse carboxylic acid derivatives. Organic & Biomolecular Chemistry. PMID 34086029 DOI: 10.1039/d1ob00786f  0.657
2020 Watve S, Barrasso K, Jung SA, Davis KJ, Hawver LA, Khataokar A, Palaganas RG, Neiditch MB, Perez LJ, Ng WL. Parallel quorum-sensing system in Vibrio cholerae prevents signal interference inside the host. Plos Pathogens. 16: e1008313. PMID 32059031 DOI: 10.1371/Journal.Ppat.1008313  0.341
2019 Flockton TR, Schnorbus L, Araujo A, Adams J, Hammel M, Perez LJ. Inhibition of Biofilm Formation with Surface Modified Polymeric Nanoparticles. Pathogens (Basel, Switzerland). 8. PMID 31022836 DOI: 10.3390/Pathogens8020055  0.31
2016 Capilato JN, Philippi SV, Reardon T, McConnell A, Oliver DC, Warren A, Adams JS, Wu C, Perez LJ. Development of a novel series of non-natural triaryl agonists and antagonists of the Pseudomonas aeruginosa LasR quorum sensing receptor. Bioorganic & Medicinal Chemistry. PMID 27825554 DOI: 10.1016/J.Bmc.2016.10.021  0.662
2016 Wu B, Capilato J, Pham MP, Walker J, Spur B, Rodriguez A, Perez LJ, Yin K. Lipoxin A4 augments host defense in sepsis and reduces Pseudomonas aeruginosa virulence through quorum sensing inhibition. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26965685 DOI: 10.1096/Fj.201500029R  0.641
2015 O'Brien KT, Noto JG, Nichols-O'Neill L, Perez LJ. Potent Irreversible Inhibitors of LasR Quorum Sensing in Pseudomonas aeruginosa. Acs Medicinal Chemistry Letters. 6: 162-7. PMID 25699144 DOI: 10.1021/Ml500459F  0.358
2015 Lu HD, Spiegel AC, Hurley A, Perez LJ, Maisel K, Ensign LM, Hanes J, Bassler BL, Semmelhack MF, Prud'homme RK. Modulating Vibrio cholerae quorum-sensing-controlled communication using autoinducer-loaded nanoparticles. Nano Letters. 15: 2235-41. PMID 25651002 DOI: 10.1021/Acs.Nanolett.5B00151  0.303
2014 Werner KM, Perez LJ, Ghosh R, Semmelhack MF, Bassler BL. Caenorhabditis elegans recognizes a bacterial quorum-sensing signal molecule through the AWCON neuron. The Journal of Biological Chemistry. 289: 26566-73. PMID 25092291 DOI: 10.1074/Jbc.M114.573832  0.303
2014 Perez LJ, Karagounis TK, Hurley A, Bassler BL, Semmelhack MF. Highly Potent, Chemically Stable Quorum Sensing Agonists for Vibrio Cholerae. Chemical Science (Royal Society of Chemistry : 2010). 5: 151-155. PMID 24436778 DOI: 10.1039/C3Sc52572D  0.35
2012 Perez LJ, Ng WL, Marano P, Brook K, Bassler BL, Semmelhack MF. Role of the CAI-1 fatty acid tail in the Vibrio cholerae quorum sensing response. Journal of Medicinal Chemistry. 55: 9669-81. PMID 23092313 DOI: 10.1021/Jm300908T  0.382
2011 Bolitho ME, Perez LJ, Koch MJ, Ng WL, Bassler BL, Semmelhack MF. Small molecule probes of the receptor binding site in the Vibrio cholerae CAI-1 quorum sensing circuit. Bioorganic & Medicinal Chemistry. 19: 6906-18. PMID 22001326 DOI: 10.1016/J.Bmc.2011.09.021  0.36
2011 Ng WL, Perez LJ, Wei Y, Kraml C, Semmelhack MF, Bassler BL. Signal production and detection specificity in Vibrio CqsA/CqsS quorum-sensing systems. Molecular Microbiology. 79: 1407-17. PMID 21219472 DOI: 10.1111/J.1365-2958.2011.07548.X  0.346
2011 Wei Y, Perez LJ, Ng WL, Semmelhack MF, Bassler BL. Mechanism of Vibrio cholerae autoinducer-1 biosynthesis. Acs Chemical Biology. 6: 356-65. PMID 21197957 DOI: 10.1021/Cb1003652  0.397
2010 Ng WL, Wei Y, Perez LJ, Cong J, Long T, Koch M, Semmelhack MF, Wingreen NS, Bassler BL. Probing bacterial transmembrane histidine kinase receptor-ligand interactions with natural and synthetic molecules. Proceedings of the National Academy of Sciences of the United States of America. 107: 5575-80. PMID 20212168 DOI: 10.1073/Pnas.1001392107  0.361
2009 Perez LJ, Shimp HL, Micalizio GC. Stereoselective synthesis of trisubstituted (E,E)-1,3-dienes by the site-selective reductive cross-coupling of internal alkynes with terminal alkynes: a fragment coupling reaction for natural product synthesis. The Journal of Organic Chemistry. 74: 7211-9. PMID 19722544 DOI: 10.1021/Jo901451C  0.601
2008 Perez LJ, Micalizio GC. Titanium-mediated fragment union processes in complex molecule synthesis: Development of a branched reaction pathway of high step economy for the synthesis of complex and diverse polyketides Synthesis. 0627-0648. DOI: 10.1055/S-2008-1032160  0.623
Low-probability matches (unlikely to be authored by this person)
2003 Perez LJ, Faulkner DJ. Bistratamides E-J, modified cyclic hexapeptides from the Philippines ascidian Lissoclinum bistratum. Journal of Natural Products. 66: 247-50. PMID 12608858 DOI: 10.1021/Np0204601  0.29
2012 Ng WL, Perez L, Cong J, Semmelhack MF, Bassler BL. Broad spectrum pro-quorum-sensing molecules as inhibitors of virulence in vibrios. Plos Pathogens. 8: e1002767. PMID 22761573 DOI: 10.1371/journal.ppat.1002767  0.245
2022 Miller Conrad LC, Perez LJ. A Geneticist Transcribing the Chemical Language of Bacteria. Israel Journal of Chemistry. 63. PMID 37469628 DOI: 10.1002/ijch.202200079  0.236
2021 White B, Sterrett JD, Grigoryan Z, Lally L, Heinze JD, Alikhan H, Lowry CA, Perez LJ, DeSipio J, Phadtare S. Characterization of gut microbiome and metabolome in patients in an underprivileged community in the United States. World Journal of Gastroenterology. 27: 5575-5594. PMID 34588753 DOI: 10.3748/wjg.v27.i33.5575  0.149
2015 Muñoz-González S, Ruggli N, Rosell R, Pérez LJ, Frías-Leuporeau MT, Fraile L, Montoya M, Cordoba L, Domingo M, Ehrensperger F, Summerfield A, Ganges L. Postnatal persistent infection with classical Swine Fever virus and its immunological implications. Plos One. 10: e0125692. PMID 25938664 DOI: 10.1371/journal.pone.0125692  0.138
2023 Paripati N, Nesi L, Sterrett JD, Dawud LM, Kessler LR, Lowry CA, Perez LJ, DeSipio J, Phadtare S. Gut Microbiome and Lipidome Signatures in Irritable Bowel Syndrome Patients from a Low-Income, Food-Desert Area: A Pilot Study. Microorganisms. 11. PMID 37894161 DOI: 10.3390/microorganisms11102503  0.129
2023 Saw YL, Boughton JR, Wroniuk FL, Mostafa ME, Pellegrinelli PJ, Calvez SA, Kaplitz AS, Perez LJ, Edwards JL, Grinias JP. Use of N-(4-aminophenyl)piperidine derivatization to improve organic acid detection with supercritical fluid chromatography-mass spectrometry. Journal of Separation Science. e2300343. PMID 37603367 DOI: 10.1002/jssc.202300343  0.123
2014 Tarradas J, de la Torre ME, Rosell R, Perez LJ, Pujols J, Muñoz M, Muñoz I, Muñoz S, Abad X, Domingo M, Fraile L, Ganges L. The impact of CSFV on the immune response to control infection. Virus Research. 185: 82-91. PMID 24657786 DOI: 10.1016/j.virusres.2014.03.004  0.109
2010 Pérez LJ, Díaz de Arce H, Percedo MI, Domínguez P, Frías MT. First report of porcine circovirus type 2 infections in Cuba. Research in Veterinary Science. 88: 528-30. PMID 20031180 DOI: 10.1016/j.rvsc.2009.11.014  0.108
2011 Pérez LJ, de Arce HD, Frias MT, Perera CL, Ganges L, Núñez JI. Molecular detection of Torque teno sus virus in lymphoid tissues in concomitant infections with other porcine viral pathogens. Research in Veterinary Science. 91: e154-7. PMID 21482428 DOI: 10.1016/j.rvsc.2011.02.012  0.102
2009 Pérez LJ, de Arce HD. Development of a polymerase chain reaction assay for the detection of pseudorabies virus in clinical samples. Brazilian Journal of Microbiology : [Publication of the Brazilian Society For Microbiology]. 40: 433-8. PMID 24031383 DOI: 10.1590/S1517-83822009000300002  0.101
2015 Núñez-Hernández F, Pérez LJ, Muñoz M, Vera G, Tomás A, Egea R, Córdoba S, Segalés J, Sánchez A, Núñez JI. Identification of microRNAs in PCV2 subclinically infected pigs by high throughput sequencing. Veterinary Research. 46: 18. PMID 25879589 DOI: 10.1186/s13567-014-0141-4  0.101
2012 Pérez LJ, Díaz de Arce H, Perera CL, Rosell R, Frías MT, Percedo MI, Tarradas J, Dominguez P, Núñez JI, Ganges L. Positive selection pressure on the B/C domains of the E2-gene of classical swine fever virus in endemic areas under C-strain vaccination. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 12: 1405-12. PMID 22580241 DOI: 10.1016/j.meegid.2012.04.030  0.095
2009 Díaz de Arce H, Pérez LJ, Frías MT, Rosell R, Tarradas J, Núñez JI, Ganges L. A multiplex RT-PCR assay for the rapid and differential diagnosis of classical swine fever and other pestivirus infections. Veterinary Microbiology. 139: 245-52. PMID 19577384 DOI: 10.1016/j.vetmic.2009.06.004  0.093
2015 Postel A, Pérez LJ, Perera CL, Schmeiser S, Meyer D, Meindl-Boehmer A, Rios L, Austermann-Busch S, Frias-Lepoureau MT, Becher P. Development of a new LAMP assay for the detection of CSFV strains from Cuba: a proof-of-concept study. Archives of Virology. 160: 1435-48. PMID 25877822 DOI: 10.1007/s00705-015-2407-1  0.091
1997 Pérez LJ, Valcárcel A, de Las Heras MA, Moses D, Baldassarre H. The storage of pure ram semen at room temperature results in capacitation of a subpopulation of spermatozoa. Theriogenology. 47: 549-58. PMID 16728007  0.091
2012 Tarradas J, Monsó M, Fraile L, de la Torre BG, Muñoz M, Rosell R, Riquelme C, Pérez LJ, Nofrarías M, Domingo M, Sobrino F, Andreu D, Ganges L. A T-cell epitope on NS3 non-structural protein enhances the B and T cell responses elicited by dendrimeric constructions against CSFV in domestic pigs. Veterinary Immunology and Immunopathology. 150: 36-46. PMID 22959286 DOI: 10.1016/J.Vetimm.2012.08.006  0.09
1997 de las Heras MA, Valcarcel A, Perez LJ. In vitro capacitating effect of gamma-aminobutyric acid in ram spermatozoa. Biology of Reproduction. 56: 964-8. PMID 9096879  0.082
1996 Pérez LJ, Valcárcel A, de las Heras MA, Moses DF, Baldassarre H. In vitro capacitation and induction of acrosomal exocytosis in ram spermatozoa as assessed by the chlortetracycline assay. Theriogenology. 45: 1037-46. PMID 16727862  0.068
2009 Pérez LJ, Díaz de Arce H. A RT-PCR assay for the detection of encephalomycarditis virus infections in pigs. Brazilian Journal of Microbiology : [Publication of the Brazilian Society For Microbiology]. 40: 988-93. PMID 24031451 DOI: 10.1590/S1517-838220090004000034  0.065
2015 Foster J, Gossett S, Burgos R, Cáceres R, Tejada C, Dominguez García L, Ambrosio Rosario A, Almonte A, Perez LJ. Improving maternity care in the Dominican Republic: a pilot study of a community-based participatory research action plan by an international healthcare team. Journal of Transcultural Nursing : Official Journal of the Transcultural Nursing Society / Transcultural Nursing Society. 26: 254-60. PMID 24793488 DOI: 10.1177/1043659614524252  0.056
2010 Foster J, Burgos R, Tejada C, Cáceres R, Altamonte AT, Perez LJ, Noboa FR, Urbaez MF, Heath A, Hilliard RC, Chiang F, Hall P. A community-based participatory research approach to explore community perceptions of the quality of maternal-newborn health services in the Dominican Republic. Midwifery. 26: 504-11. PMID 20692744 DOI: 10.1016/j.midw.2010.06.001  0.055
2015 Alfonso-Morales A, Rios L, Martínez-Pérez O, Dolz R, Valle R, Perera CL, Bertran K, Frías MT, Ganges L, Díaz de Arce H, Majó N, Núñez JI, Pérez LJ. Evaluation of a Phylogenetic Marker Based on Genomic Segment B of Infectious Bursal Disease Virus: Facilitating a Feasible Incorporation of this Segment to the Molecular Epidemiology Studies for this Viral Agent. Plos One. 10: e0125853. PMID 25946336 DOI: 10.1371/journal.pone.0125853  0.052
2006 Pérez LJ, Peñas PF, Atienzar M, García-Díez A. Implication of MT1-MMP in the maturation steps of benign melanocytic nevi. Journal of Cutaneous Pathology. 33: 139-44. PMID 16420309 DOI: 10.1111/j.0303-6987.2006.00388.x  0.051
2011 Pérez LJ, Díaz de Arce H, Tarradas J, Rosell R, Perera CL, Muñoz M, Frías MT, Nuñez JI, Ganges L. Development and validation of a novel SYBR Green real-time RT-PCR assay for the detection of classical swine fever virus evaluated on different real-time PCR platforms. Journal of Virological Methods. 174: 53-9. PMID 21458490 DOI: 10.1016/j.jviromet.2011.03.022  0.046
2012 Acevedo AM, Díaz de Arce H, Brandão PE, Colas M, Oliveira S, Pérez LJ. First evidence of the emergence of novel putative infectious bronchitis virus genotypes in Cuba. Research in Veterinary Science. 93: 1046-9. PMID 22357366 DOI: 10.1016/j.rvsc.2012.01.012  0.046
2013 Acevedo AM, Perera CL, Vega A, Ríos L, Coronado L, Relova D, Frías MT, Ganges L, Núñez JI, Pérez LJ. A duplex SYBR Green I-based real-time RT-PCR assay for the simultaneous detection and differentiation of Massachusetts and non-Massachusetts serotypes of infectious bronchitis virus. Molecular and Cellular Probes. 27: 184-92. PMID 23810983 DOI: 10.1016/j.mcp.2013.06.001  0.046
2013 Pérez LJ, Perera CL, Vega A, Frías MT, Rouseaux D, Ganges L, Nuñez JI, Díaz de Arce H. Isolation and complete genomic characterization of pandemic H1N1/2009 influenza viruses from Cuban swine herds. Research in Veterinary Science. 94: 781-8. PMID 23318219 DOI: 10.1016/j.rvsc.2012.11.018  0.041
2012 Foster JW, Chiang F, Burgos RI, Cáceres RE, Tejada CM, Almonte AT, Noboa FR, Perez LJ, Urbaez MF, Heath A. Community-based participatory research and the challenges of qualitative analysis enacted by lay, nurse, and academic researchers. Research in Nursing & Health. 35: 550-9. PMID 22911059 DOI: 10.1002/nur.21494  0.04
2015 Núñez-Hernández F, Pérez LJ, Vera G, Córdoba S, Segalés J, Sánchez A, Núñez JI. Evaluation of the capability of the PCV2 genome to encode miRNAs: lack of viral miRNA expression in an experimental infection. Veterinary Research. 46: 48. PMID 25934266 DOI: 10.1186/s13567-015-0181-4  0.039
2023 Guarnaccia A, Ng WL, Steenhaut A, Olenic S, Perez LJ, Neiditch MB. Erratum: 498 Structural Determination of the CqsR CACHE Domain and its Autoinducer - CORRIGENDUM. Journal of Clinical and Translational Science. 7: e134. PMID 37396816 DOI: 10.1017/cts.2023.551  0.034
2015 Pérez LJ, Perera CL, Coronado L, Rios L, Vega A, Frías MT, Ganges L, Núñez JI, Díaz de Arce H. Molecular epidemiology study of swine influenza virus revealing a reassorted virus H1N1 in swine farms in Cuba. Preventive Veterinary Medicine. 119: 172-8. PMID 25745869 DOI: 10.1016/j.prevetmed.2015.02.013  0.034
2010 Pérez LJ, Díaz de Arce H, Frías MT. Genetic characterization and phylogenetic analysis of porcine circovirus type 2 strains present in Cuban swine herds. Research in Veterinary Science. 89: 301-5. PMID 20347107 DOI: 10.1016/j.rvsc.2010.03.013  0.03
2013 Alfonso-Morales A, Martínez-Pérez O, Dolz R, Valle R, Perera CL, Bertran K, Frías MT, Majó N, Ganges L, Pérez LJ. Spatiotemporal Phylogenetic Analysis and Molecular Characterisation of Infectious Bursal Disease Viruses Based on the VP2 Hyper-Variable Region. Plos One. 8: e65999. PMID 23805195 DOI: 10.1371/journal.pone.0065999  0.027
2012 Martínez N, Brandão PE, de Souza SP, Barrera M, Santana N, de Arce HD, Pérez LJ. Molecular and phylogenetic analysis of bovine coronavirus based on the spike glycoprotein gene. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases. 12: 1870-8. PMID 22634277 DOI: 10.1016/j.meegid.2012.05.007  0.026
2012 Pérez LJ, Perera CL, Frías MT, Núñez JI, Ganges L, de Arce HD. A multiple SYBR Green I-based real-time PCR system for the simultaneous detection of porcine circovirus type 2, porcine parvovirus, pseudorabies virus and Torque teno sus virus 1 and 2 in pigs. Journal of Virological Methods. 179: 233-41. PMID 22119629 DOI: 10.1016/j.jviromet.2011.11.009  0.025
2011 Pérez LJ, de Arce HD, Cortey M, Domínguez P, Percedo MI, Perera CL, Tarradas J, Frías MT, Segalés J, Ganges L, Núñez JI. Phylogenetic networks to study the origin and evolution of porcine circovirus type 2 (PCV2) in Cuba. Veterinary Microbiology. 151: 245-54. PMID 21507587 DOI: 10.1016/j.vetmic.2011.03.022  0.014
2015 Gallimberti L, Buja A, Chindamo S, Terraneo A, Marini E, Rabensteiner A, Vinelli A, Perez LJ, Baldo V. Problematic cell phone use for text messaging and substance abuse in early adolescence (11- to 13-year-olds). European Journal of Pediatrics. PMID 26475349 DOI: 10.1007/s00431-015-2645-y  0.012
2005 Borra A, Perez LJ, Min T, Puavilai W, Seo N, Tipsunthonsak N. Panel 2.5: mass-casualty management and hospital care. Prehospital and Disaster Medicine. 20: 412-3. PMID 16496625  0.01
Hide low-probability matches.