Jeffrey J. Bednarski, Ph.D. - Publications

Affiliations: 
2003 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
anti-DNA autoantibody structure and function, and the identification of novel molecular targets and small molecules for the treatment of autoimmune diseases and cancer

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Franco M, Panas MW, Marino ND, Lee MC, Buchholz KR, Kelly FD, Bednarski JJ, Sleckman BP, Pourmand N, Boothroyd JC. A Novel Secreted Protein, MYR1, Is Central to Toxoplasma's Manipulation of Host Cells. Mbio. 7. PMID 26838724 DOI: 10.1128/mBio.02231-15  0.48
2016 Bednarski JJ, Pandey R, Schulte E, White LS, Chen BR, Sandoval GJ, Kohyama M, Haldar M, Nickless A, Trott A, Cheng G, Murphy KM, Bassing CH, Payton JE, Sleckman BP. RAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals. The Journal of Experimental Medicine. PMID 26834154 DOI: 10.1084/jem.20151048  0.48
2016 Liu C, Duffy B, Bednarski JJ, Calhoun C, Lay L, Rundblad B, Payton JE, Mohanakumar T. Maternal T-Cell Engraftment Interferes With Human Leukocyte Antigen Typing in Severe Combined Immunodeficiency. American Journal of Clinical Pathology. PMID 26834123 DOI: 10.1093/ajcp/aqv079  0.48
2015 Bednarski JJ. DNA damage signals inhibit neutrophil function. Blood. 126: 2773-4. PMID 26705340 DOI: 10.1182/blood-2015-11-678672  0.48
2015 Koues OI, Kowalewski RA, Chang LW, Pyfrom SC, Schmidt JA, Luo H, Sandoval LE, Hughes TB, Bednarski JJ, Cashen AF, Payton JE, Oltz EM. Enhancer sequence variants and transcription-factor deregulation synergize to construct pathogenic regulatory circuits in B-cell lymphoma. Immunity. 42: 186-98. PMID 25607463 DOI: 10.1016/j.immuni.2014.12.021  0.48
2013 Steinel NC, Lee BS, Tubbs AT, Bednarski JJ, Schulte E, Yang-Iott KS, Schatz DG, Sleckman BP, Bassing CH. The ataxia telangiectasia mutated kinase controls Igκ allelic exclusion by inhibiting secondary Vκ-to-Jκ rearrangements. The Journal of Experimental Medicine. 210: 233-9. PMID 23382544 DOI: 10.1084/jem.20121605  0.48
2012 Bednarski JJ, Sleckman BP. Lymphocyte development: integration of DNA damage response signaling. Advances in Immunology. 116: 175-204. PMID 23063077 DOI: 10.1016/B978-0-12-394300-2.00006-5  0.48
2012 Bednarski JJ, Sleckman BP. Integrated signaling in developing lymphocytes: the role of DNA damage responses. Cell Cycle (Georgetown, Tex.). 11: 4129-34. PMID 23032308 DOI: 10.4161/cc.22021  0.48
2012 Bednarski JJ, Nickless A, Bhattacharya D, Amin RH, Schlissel MS, Sleckman BP. RAG-induced DNA double-strand breaks signal through Pim2 to promote pre-B cell survival and limit proliferation. The Journal of Experimental Medicine. 209: 11-7. PMID 22201128 DOI: 10.1084/jem.20112078  0.48
2011 Gapud EJ, Dorsett Y, Yin B, Callen E, Bredemeyer A, Mahowald GK, Omi KQ, Walker LM, Bednarski JJ, McKinnon PJ, Bassing CH, Nussenzweig A, Sleckman BP. Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation. Proceedings of the National Academy of Sciences of the United States of America. 108: 2022-7. PMID 21245316 DOI: 10.1073/pnas.1013295108  0.48
2011 Helmink BA, Tubbs AT, Dorsett Y, Bednarski JJ, Walker LM, Feng Z, Sharma GG, McKinnon PJ, Zhang J, Bassing CH, Sleckman BP. H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes. Nature. 469: 245-9. PMID 21160476 DOI: 10.1038/nature09585  0.48
2011 Helmink BA, Tubbs AT, Dorsett Y, Bednarski JJ, M.walker L, Feng Z, Sharma GG, McKinnon PJ, Zhang J, Bassing CH, Sleckman BP. H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes (Nature 469 (2010) (245-249)) Nature. 472: 247. DOI: 10.1038/nature09942  0.48
2009 Helmink BA, Bredemeyer AL, Lee BS, Huang CY, Sharma GG, Walker LM, Bednarski JJ, Lee WL, Pandita TK, Bassing CH, Sleckman BP. MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks. The Journal of Experimental Medicine. 206: 669-79. PMID 19221393 DOI: 10.1084/jem.20081326  0.48
2004 Bednarski JJ, Lyssiotis CA, Roush R, Boitano AE, Glick GD, Opipari AW. A novel benzodiazepine increases the sensitivity of B cells to receptor stimulation with synergistic effects on calcium signaling and apoptosis. The Journal of Biological Chemistry. 279: 29615-21. PMID 15123639 DOI: 10.1074/jbc.M403507200  0.48
2003 Bednarski JJ, Warner RE, Rao T, Leonetti F, Yung R, Richardson BC, Johnson KJ, Ellman JA, Opipari AW, Glick GD. Attenuation of autoimmune disease in Fas-deficient mice by treatment with a cytotoxic benzodiazepine. Arthritis and Rheumatism. 48: 757-66. PMID 12632430 DOI: 10.1002/art.10968  0.48
2002 Blatt NB, Bednarski JJ, Warner RE, Leonetti F, Johnson KM, Boitano A, Yung R, Richardson BC, Johnson KJ, Ellman JA, Opipari AW, Glick GD. Benzodiazepine-induced superoxide signals B cell apoptosis: mechanistic insight and potential therapeutic utility. The Journal of Clinical Investigation. 110: 1123-32. PMID 12393848 DOI: 10.1172/JCI16029  0.48
1998 Chung SH, Song WJ, Kim K, Bednarski JJ, Chen J, Prestwich GD, Holz RW. The C2 domains of Rabphilin3A specifically bind phosphatidylinositol 4,5-bisphosphate containing vesicles in a Ca2+-dependent manner. In vitro characteristics and possible significance. The Journal of Biological Chemistry. 273: 10240-8. PMID 9553075 DOI: 10.1074/jbc.273.17.10240  0.48
1996 Clementz T, Bednarski JJ, Raetz CR. Function of the htrB high temperature requirement gene of Escherichia coli in the acylation of lipid A: HtrB catalyzed incorporation of laurate. The Journal of Biological Chemistry. 271: 12095-102. PMID 8662613  0.48
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