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Jeffrey J. Bednarski, Ph.D. - Publications

Affiliations: 
2003 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
anti-DNA autoantibody structure and function, and the identification of novel molecular targets and small molecules for the treatment of autoimmune diseases and cancer
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34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Johnston R, Mathias B, Crowley SJ, Schmidt HA, White LS, Mosammaparast N, Green AM, Bednarski JJ. Nuclease-independent functions of RAG1 direct distinct DNA damage responses in B cells. Embo Reports. e55429. PMID 36382770 DOI: 10.15252/embr.202255429  0.405
2022 Johnston R, White LS, Bednarski JJ. Assessing DNA Damage Responses Using B Lymphocyte Cultures. Methods in Molecular Biology (Clifton, N.J.). 2444: 69-80. PMID 35290632 DOI: 10.1007/978-1-0716-2063-2_5  0.305
2020 Bhatt ST, Bednarski JJ. Immune Reconstitution in Pediatric Patients Following Hematopoietic Cell Transplant for Non-malignant Disorders. Frontiers in Immunology. 11: 1988. PMID 33013851 DOI: 10.3389/Fimmu.2020.01988  0.32
2020 Blincoe A, Heeg M, Campbell PK, Hines M, Khojah A, Klein-Gitelman M, Talano JA, Speckmann C, Touzot F, Lankester A, Legger GE, Rivière JG, Garcia-Prat M, Alonso L, Putti MC, ... ... Bednarski JJ, et al. Neuroinflammatory Disease as an Isolated Manifestation of Hemophagocytic Lymphohistiocytosis. Journal of Clinical Immunology. PMID 32638196 DOI: 10.1007/S10875-020-00814-6  0.302
2020 Chan AY, Leiding JW, Liu X, Logan BR, Burroughs LM, Allenspach EJ, Skoda-Smith S, Uzel G, Notarangelo LD, Slatter M, Gennery AR, Smith AR, Pai SY, Jordan MB, Marsh RA, ... ... Bednarski JJ, et al. Hematopoietic Cell Transplantation in Patients With Primary Immune Regulatory Disorders (PIRD): A Primary Immune Deficiency Treatment Consortium (PIDTC) Survey. Frontiers in Immunology. 11: 239. PMID 32153572 DOI: 10.3389/Fimmu.2020.00239  0.36
2020 Keller MD, Hanley PJ, Zhang N, Tanna J, Fatic A, Lang H, Ekanem U, Sani GM, Aguayo-Hiraldo PI, Quigg TC, Verneris MR, Parikh S, Dvorak CC, Satwani P, Davila B, ... Bednarski JJ, et al. Third-Party Virus-Specific T-Cell Infusion for Treatment of Refractory Viral Infections: Interim Results from PBMTC SUP1701 Biology of Blood and Marrow Transplantation. 26: S89-S90. DOI: 10.1016/J.Bbmt.2019.12.591  0.339
2020 Thakar MS, Logan B, Buckley RH, Haddad E, Dvorak CC, O'Reilly RJ, Kapoor N, Satter LF, Martinez C, Pai S, Heimall J, Jyonouchi S, Sullivan KE, Chandra S, Smith AR, ... ... Bednarski JJ, et al. Transplantation Outcomes for Children with Severe Combined Immune Deficiency (SCID) Have Improved over Time: A 36-Year Summary Report By the Primary Immune Deficiency Treatment Consortium (PIDTC) Biology of Blood and Marrow Transplantation. 26: S18-S19. DOI: 10.1016/J.Bbmt.2019.12.083  0.321
2019 Greenberg ZJ, Monlish DA, Bartnett RL, Yang Y, Shen G, Li W, Bednarski JJ, Schuettpelz LG. The Tetraspanin CD53 Regulates Early B Cell Development by Promoting IL-7R Signaling. Journal of Immunology (Baltimore, Md. : 1950). PMID 31748347 DOI: 10.1182/Blood-2019-131641  0.404
2019 Soodgupta D, White LS, Yang W, Johnston R, Andrews JM, Kohyama M, Murphy KM, Mosammaparast N, Payton JE, Bednarski JJ. RAG-Mediated DNA Breaks Attenuate PU.1 Activity in Early B Cells through Activation of a SPIC-BCLAF1 Complex. Cell Reports. 29: 829-843.e5. PMID 31644907 DOI: 10.1016/J.Celrep.2019.09.026  0.404
2019 Bhatt ST, Schulz G, Hente M, Slater A, Murray L, Shenoy S, Bednarski JJ. A single-center experience using alemtuzumab, fludarabine, melphalan, and thiotepa as conditioning for transplantation in pediatric patients with chronic granulomatous disease. Pediatric Blood & Cancer. e28030. PMID 31599480 DOI: 10.1002/Pbc.28030  0.317
2019 Bednarski JJ, Sleckman BP. At the intersection of DNA damage and immune responses. Nature Reviews. Immunology. PMID 30778174 DOI: 10.1038/S41577-019-0135-6  0.373
2019 Bednarski JJ, Zimmerman C, Cashen AF, Desai S, Foster M, Schappe T, McClain E, Becker-Hapak M, Berrien-Elliott MM, Fehniger TA. Adoptively Transferred Donor-Derived Cytokine Induced Memory-like NK Cells Persist and Induce Remission in Pediatric Patient with Relapsed Acute Myeloid Leukemia after Hematopoietic Cell Transplantation Blood. 134: 3307-3307. DOI: 10.1182/Blood-2019-126982  0.408
2018 Bhatt ST, Bednarski JJ, Berg J, Trinkaus K, Murray L, Hayashi R, Schulz G, Hente M, Grimley M, Chan KW, Kamani N, Jacobsohn D, Nieder M, Hale G, Yu L, et al. Immune Reconstitution and Infection Patterns Following Early Alemtuzumab and Reduced Intensity Transplantation for Non-Malignant Disorders in Pediatric Patients. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 30321596 DOI: 10.1016/J.Bbmt.2018.10.008  0.357
2018 Fistonich C, Zehentmeier S, Bednarski JJ, Miao R, Schjerven H, Sleckman BP, Pereira JP. Cell circuits between B cell progenitors and IL-7 mesenchymal progenitor cells control B cell development. The Journal of Experimental Medicine. PMID 30158115 DOI: 10.1084/Jem.20180778  0.388
2018 Haddad E, Logan BR, Griffith LM, Buckley RH, Parrot RE, Prockop SE, Small TN, Chaisson J, Dvorak CC, Murnane M, Kapoor N, Abdel-Azim H, Hanson IC, Martinez C, Bleesing JJH, ... ... Bednarski JJ, et al. SCID genotype and 6-month post-transplant CD4 count predict survival and immune recovery: a PIDTC retrospective study. Blood. PMID 30154114 DOI: 10.1182/Blood-2018-03-840702  0.364
2018 White LS, Soodgupta D, Johnston RL, Magee JA, Bednarski JJ. Bclaf1 Promotes Maintenance and Self-Renewal of Fetal Hematopoietic Stem Cells Blood. 132: 1269-1269. DOI: 10.1182/Blood-2018-99-114144  0.389
2017 Haddad E, Logan BR, Griffith LM, Buckley RH, Parrott RE, Dvorak CC, Puck J, Prockop SE, Kapoor N, Abdel-Azim H, Hanson IC, Martinez C, Bleesing J, Chandra S, Smith AR, ... ... Bednarski JJ, et al. Genotype, Phenotype and T Cell Counts at One Year Predict Survival and Long Term Immune Reconstitution after Transplantation in Severe Combined Immune Deficiency (SCID)—The Primary Immune Deficiency Treatment Consortium (PIDTC) Biology of Blood and Marrow Transplantation. 23: S133-S134. DOI: 10.1016/J.Bbmt.2017.01.052  0.322
2016 Franco M, Panas MW, Marino ND, Lee MC, Buchholz KR, Kelly FD, Bednarski JJ, Sleckman BP, Pourmand N, Boothroyd JC. A Novel Secreted Protein, MYR1, Is Central to Toxoplasma's Manipulation of Host Cells. Mbio. 7. PMID 26838724 DOI: 10.1128/Mbio.02231-15  0.309
2016 Bednarski JJ, Pandey R, Schulte E, White LS, Chen BR, Sandoval GJ, Kohyama M, Haldar M, Nickless A, Trott A, Cheng G, Murphy KM, Bassing CH, Payton JE, Sleckman BP. RAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals. The Journal of Experimental Medicine. PMID 26834154 DOI: 10.1084/Jem.20151048  0.473
2016 Liu C, Duffy B, Bednarski JJ, Calhoun C, Lay L, Rundblad B, Payton JE, Mohanakumar T. Maternal T-Cell Engraftment Interferes With Human Leukocyte Antigen Typing in Severe Combined Immunodeficiency. American Journal of Clinical Pathology. PMID 26834123 DOI: 10.1093/Ajcp/Aqv079  0.317
2015 Bednarski JJ. DNA damage signals inhibit neutrophil function. Blood. 126: 2773-4. PMID 26705340 DOI: 10.1182/Blood-2015-11-678672  0.362
2015 Koues OI, Kowalewski RA, Chang LW, Pyfrom SC, Schmidt JA, Luo H, Sandoval LE, Hughes TB, Bednarski JJ, Cashen AF, Payton JE, Oltz EM. Enhancer sequence variants and transcription-factor deregulation synergize to construct pathogenic regulatory circuits in B-cell lymphoma. Immunity. 42: 186-98. PMID 25607463 DOI: 10.1016/J.Immuni.2014.12.021  0.422
2013 Steinel NC, Lee BS, Tubbs AT, Bednarski JJ, Schulte E, Yang-Iott KS, Schatz DG, Sleckman BP, Bassing CH. The ataxia telangiectasia mutated kinase controls Igκ allelic exclusion by inhibiting secondary Vκ-to-Jκ rearrangements. The Journal of Experimental Medicine. 210: 233-9. PMID 23382544 DOI: 10.1084/Jem.20121605  0.357
2013 Bednarski JJ, Le C, Murray L, Hayashi R, Yu L, Dalal J, Kamani N, Jacobsohn DA, Pulsipher MA, Petrovic A, Chan KW, Grimley M, Haut P, Adams R, Douglas D, et al. Immune Reconstitution Following Reduced Intensity Stem Cell Transplantation for Non-Malignant Disorders in Children Biology of Blood and Marrow Transplantation. 19: S200. DOI: 10.1016/J.Bbmt.2012.11.218  0.317
2012 Bednarski JJ, Sleckman BP. Lymphocyte development: integration of DNA damage response signaling. Advances in Immunology. 116: 175-204. PMID 23063077 DOI: 10.1016/B978-0-12-394300-2.00006-5  0.422
2012 Bednarski JJ, Sleckman BP. Integrated signaling in developing lymphocytes: the role of DNA damage responses. Cell Cycle (Georgetown, Tex.). 11: 4129-34. PMID 23032308 DOI: 10.4161/Cc.22021  0.376
2012 Bednarski JJ, Nickless A, Bhattacharya D, Amin RH, Schlissel MS, Sleckman BP. RAG-induced DNA double-strand breaks signal through Pim2 to promote pre-B cell survival and limit proliferation. The Journal of Experimental Medicine. 209: 11-7. PMID 22201128 DOI: 10.1084/Jem.20112078  0.451
2012 Trott A, Bednarski J, Sleckman B. Physiologic DNA Breaks Activate Non-canonical NFkB Signaling in Developing B Cells Journal of Allergy and Clinical Immunology. 129: AB12. DOI: 10.1016/J.Jaci.2011.12.908  0.427
2011 Gapud EJ, Dorsett Y, Yin B, Callen E, Bredemeyer A, Mahowald GK, Omi KQ, Walker LM, Bednarski JJ, McKinnon PJ, Bassing CH, Nussenzweig A, Sleckman BP. Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation. Proceedings of the National Academy of Sciences of the United States of America. 108: 2022-7. PMID 21245316 DOI: 10.1073/Pnas.1013295108  0.315
2011 Helmink BA, Tubbs AT, Dorsett Y, Bednarski JJ, Walker LM, Feng Z, Sharma GG, McKinnon PJ, Zhang J, Bassing CH, Sleckman BP. H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes. Nature. 469: 245-9. PMID 21160476 DOI: 10.1038/Nature09585  0.339
2009 Helmink BA, Bredemeyer AL, Lee BS, Huang CY, Sharma GG, Walker LM, Bednarski JJ, Lee WL, Pandita TK, Bassing CH, Sleckman BP. MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks. The Journal of Experimental Medicine. 206: 669-79. PMID 19221393 DOI: 10.1084/Jem.20081326  0.339
2004 Bednarski JJ, Lyssiotis CA, Roush R, Boitano AE, Glick GD, Opipari AW. A novel benzodiazepine increases the sensitivity of B cells to receptor stimulation with synergistic effects on calcium signaling and apoptosis. The Journal of Biological Chemistry. 279: 29615-21. PMID 15123639 DOI: 10.1074/Jbc.M403507200  0.695
2003 Bednarski JJ, Warner RE, Rao T, Leonetti F, Yung R, Richardson BC, Johnson KJ, Ellman JA, Opipari AW, Glick GD. Attenuation of autoimmune disease in Fas-deficient mice by treatment with a cytotoxic benzodiazepine. Arthritis and Rheumatism. 48: 757-66. PMID 12632430 DOI: 10.1002/Art.10968  0.624
2002 Blatt NB, Bednarski JJ, Warner RE, Leonetti F, Johnson KM, Boitano A, Yung R, Richardson BC, Johnson KJ, Ellman JA, Opipari AW, Glick GD. Benzodiazepine-induced superoxide signals B cell apoptosis: mechanistic insight and potential therapeutic utility. The Journal of Clinical Investigation. 110: 1123-32. PMID 12393848 DOI: 10.1172/Jci16029  0.59
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