Angela S. Fleischhacker, Ph.D. - Publications

2007 University of Michigan, Ann Arbor, Ann Arbor, MI 
Mechanisms of B12- and folate dependent enzymes

12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.


Year Citation  Score
2015 Davydov R, Fleischhacker AS, Bagai I, Hoffman BM, Ragsdale SW. Comparison of the Mechanisms of Heme Hydroxylation by Heme Oxygenases-1 and -2: Kinetic and Cryoreduction Studies. Biochemistry. PMID 26652036 DOI: 10.1021/acs.biochem.5b00943  0.96
2015 Fleischhacker AS, Sharma A, Choi M, Spencer AM, Bagai I, Hoffman BM, Ragsdale SW. The C-terminal heme regulatory motifs of heme oxygenase-2 are redox-regulated heme binding sites. Biochemistry. 54: 2709-18. PMID 25853617 DOI: 10.1021/acs.biochem.5b00266  0.96
2015 Bagai I, Sarangi R, Fleischhacker AS, Sharma A, Hoffman BM, Zuiderweg ER, Ragsdale SW. Spectroscopic studies reveal that the heme regulatory motifs of heme oxygenase-2 are dynamically disordered and exhibit redox-dependent interaction with heme. Biochemistry. 54: 2693-708. PMID 25849895 DOI: 10.1021/bi501489r  0.96
2013 Giel JL, Nesbit AD, Mettert EL, Fleischhacker AS, Wanta BT, Kiley PJ. Regulation of iron-sulphur cluster homeostasis through transcriptional control of the Isc pathway by [2Fe-2S]-IscR in Escherichia coli. Molecular Microbiology. 87: 478-92. PMID 23075318 DOI: 10.1111/mmi.12052  0.96
2012 Nesbit AD, Fleischhacker AS, Teter SJ, Kiley PJ. ArcA and AppY antagonize IscR repression of hydrogenase-1 expression under anaerobic conditions, revealing a novel mode of O2 regulation of gene expression in Escherichia coli. Journal of Bacteriology. 194: 6892-9. PMID 23065979 DOI: 10.1128/JB.01757-12  0.96
2012 Fleischhacker AS, Stubna A, Hsueh KL, Guo Y, Teter SJ, Rose JC, Brunold TC, Markley JL, Münck E, Kiley PJ. Characterization of the [2Fe-2S] cluster of Escherichia coli transcription factor IscR. Biochemistry. 51: 4453-62. PMID 22583201 DOI: 10.1021/bi3003204  0.96
2012 Mohrig JR, Beyer BG, Fleischhacker AS, Ruthenburg AJ, John SG, Snyder DA, Nyffeler PT, Noll RJ, Penner ND, Phillips LA, Hurley HL, Jacobs JS, Treitel C, James TL, Montgomery MP. Does activation of the anti proton, rather than concertedness, determine the stereochemistry of base-catalyzed 1,2-elimination reactions? Anti stereospecificity in E1cB eliminations of β-3-trifluoromethylphenoxy esters, thioesters, and ketones. The Journal of Organic Chemistry. 77: 2819-28. PMID 22321002 DOI: 10.1021/jo300053w  0.96
2011 Fleischhacker AS, Kiley PJ. Iron-containing transcription factors and their roles as sensors. Current Opinion in Chemical Biology. 15: 335-41. PMID 21292540 DOI: 10.1016/j.cbpa.2011.01.006  0.96
2009 Liptak MD, Fleischhacker AS, Matthews RG, Telser J, Brunold TC. Spectroscopic and computational characterization of the base-off forms of cob(II)alamin. The Journal of Physical Chemistry. B. 113: 5245-54. PMID 19298066 DOI: 10.1021/jp810136d  0.96
2007 Fleischhacker AS, Matthews RG. Ligand trans influence governs conformation in cobalamin-dependent methionine synthase. Biochemistry. 46: 12382-92. PMID 17924667 DOI: 10.1021/bi701367c  0.96
2007 Liptak MD, Fleischhacker AS, Matthews RG, Brunold TC. Probing the role of the histidine 759 ligand in cobalamin-dependent methionine synthase. Biochemistry. 46: 8024-35. PMID 17567043 DOI: 10.1021/bi700341y  0.96
2004 Li J, Wu J, Fleischhacker AS, Woodard RW. Conversion of aquifex aeolicus 3-deoxy-d-manno-octulosonate 8-phosphate synthase, a metalloenzyme, into a nonmetalloenzyme. Journal of the American Chemical Society. 126: 7448-9. PMID 15198585 DOI: 10.1021/ja0480872  0.96
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