Michelle R. Garnsey, Ph.D. - Publications

2012 Chemistry Duke University, Durham, NC 

8 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Davoren JE, Lee CW, Garnsey M, Brodney MA, Cordes J, Dlugolenski K, Edgerton JR, Harris AR, Helal CJ, Jenkinson S, Kauffman GW, Kenakin T, Lazzaro JT, Lotarski SM, Mao Y, et al. Discovery of the potent and selective M1 PAM-agonist N-[(3R,4S)-3-hydroxytetrahydro-2H-pyran-4-yl]-5-methyl-4-[4-(1,3-thiazol-4-yl)benzyl]pyridine-2-carboxamide (PF-06767832): Evaluation of efficacy and cholinergic side effects. Journal of Medicinal Chemistry. PMID 27275946 DOI: 10.1021/Acs.Jmedchem.6B00544  1
2015 Garnsey MR, Uteuliyev MM, Coltart DM. Asymmetric synthesis of structural analogues of (+)-clusianone via enantioselective ACC alkylation Tetrahedron Letters. 56: 3183-3185. DOI: 10.1016/J.Tetlet.2015.01.012  1
2011 Garnsey MR, Matous JA, Kwiek JJ, Coltart DM. Asymmetric total synthesis of (+)- and (-)-clusianone and (+)- and (-)-clusianone methyl enol ether via ACC alkylation and evaluation of their anti-HIV activity. Bioorganic & Medicinal Chemistry Letters. 21: 2406-9. PMID 21414776 DOI: 10.1016/J.Bmcl.2011.02.074  1
2010 Garnsey MR, Lim D, Yost JM, Coltart DM. Development of a strategy for the asymmetric synthesis of polycyclic polyprenylated acylphloroglucinols via N-amino cyclic carbamate hydrazones: application to the total synthesis of (+)-clusianone. Organic Letters. 12: 5234-7. PMID 20977254 DOI: 10.1021/Ol1022728  1
2010 Sauer SJ, Garnsey MR, Coltart DM. Direct carbon-carbon bond formation via reductive soft enolization: a kinetically controlled syn-aldol addition of α-halo thioesters and enolizable aldehydes. Journal of the American Chemical Society. 132: 13997-9. PMID 20849119 DOI: 10.1021/Ja1057407  1
2010 Kohler MC, Yost JM, Garnsey MR, Coltart DM. Direct carbon-carbon bond formation via soft enolization: a biomimetic asymmetric Mannich reaction of phenylacetate thioesters. Organic Letters. 12: 3376-9. PMID 20608684 DOI: 10.1021/Ol101152B  1
2009 Yost JM, Garnsey MR, Kohler MC, Coltart DM. Direct carbon-carbon bond formation via soft enolization of thioesters: An operationally simple mannich addition reaction Synthesis. 56-58. DOI: 10.1055/S-0028-1083278  1
2008 Castle SA, Owuor EA, Thompson SH, Garnsey MR, Klutts JS, Doering TL, Levery SB. Beta1,2-xylosyltransferase Cxt1p is solely responsible for xylose incorporation into Cryptococcus neoformans glycosphingolipids. Eukaryotic Cell. 7: 1611-5. PMID 18676952 DOI: 10.1128/Ec.00458-07  1
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