Bhushan Nagar, Ph.D. - Publications

Affiliations: 
2001 University of Toronto, Toronto, ON, Canada 
Area:
sturucture of glycosyltransferases

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Dementiev A, Joachimiak A, Nguyen H, Gorelik A, Illes K, Shabani S, Gelsomino M, Ahn EE, Nagar B, Doan N. Molecular mechanism of inhibition of acid ceramidase by carmofur. Journal of Medicinal Chemistry. PMID 30525581 DOI: 10.2210/Pdb6Mhm/Pdb  0.301
2018 Gorelik A, Gebai A, Illes K, Piomelli D, Nagar B. Molecular mechanism of activation of the immunoregulatory amidase NAAA. Proceedings of the National Academy of Sciences of the United States of America. PMID 30301806 DOI: 10.1073/Pnas.1811759115  0.34
2018 Labriola J, Zhou Y, Nagar B. Structural analysis of the bacterial effector, AvrA, identifies a critical helix involved in MKK4-substrate recognition. Biochemistry. PMID 30025209 DOI: 10.1021/Acs.Biochem.8B00512  0.402
2013 Trempe JF, Sauvé V, Grenier K, Seirafi M, Tang MY, Ménade M, Al-Abdul-Wahid S, Krett J, Wong K, Kozlov G, Nagar B, Fon EA, Gehring K. Structure of parkin reveals mechanisms for ubiquitin ligase activation. Science (New York, N.Y.). 340: 1451-5. PMID 23661642 DOI: 10.1126/Science.1237908  0.343
2013 Fabian MR, Frank F, Rouya C, Siddiqui N, Lai WS, Karetnikov A, Blackshear PJ, Nagar B, Sonenberg N. Structural basis for the recruitment of the human CCR4-NOT deadenylase complex by tristetraprolin. Nature Structural & Molecular Biology. 20: 735-9. PMID 23644599 DOI: 10.1038/Nsmb.2572  0.358
2013 Ishiyama N, Tanaka N, Abe K, Yang YJ, Abbas YM, Umitsu M, Nagar B, Bueler SA, Rubinstein JL, Takeichi M, Ikura M. An autoinhibited structure of α-catenin and its implications for vinculin recruitment to adherens junctions. The Journal of Biological Chemistry. 288: 15913-25. PMID 23589308 DOI: 10.1074/Jbc.M113.453928  0.307
2013 Virgili G, Frank F, Feoktistova K, Sawicki M, Sonenberg N, Fraser CS, Nagar B. Structural analysis of the DAP5 MIF4G domain and its interaction with eIF4A. Structure (London, England : 1993). 21: 517-27. PMID 23478064 DOI: 10.1016/J.Str.2013.01.015  0.382
2012 Frank F, Hauver J, Sonenberg N, Nagar B. Arabidopsis Argonaute MID domains use their nucleotide specificity loop to sort small RNAs. The Embo Journal. 31: 3588-95. PMID 22850669 DOI: 10.1038/Emboj.2012.204  0.339
2012 Amaefuna SC, Harrington AM, Jean-Claude B, Nagar B, Henderson MN. Crystallization of the Abl Kinase Domain with Combi-Inhibitors, ZRF1 and ZRF2 Biophysical Journal. 102: 61a. DOI: 10.1016/J.Bpj.2011.11.364  0.362
2011 Frank F, Fabian MR, Stepinski J, Jemielity J, Darzynkiewicz E, Sonenberg N, Nagar B. Structural analysis of 5'-mRNA-cap interactions with the human AGO2 MID domain. Embo Reports. 12: 415-20. PMID 21475248 DOI: 10.1038/Embor.2011.48  0.321
2010 Frank F, Sonenberg N, Nagar B. Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2. Nature. 465: 818-22. PMID 20505670 DOI: 10.1038/Nature09039  0.335
2010 Frank F, Virgili G, Sonenberg N, Nagar B. Crystallization and preliminary X-ray diffraction analysis of the MIF4G domain of DAP5. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 15-9. PMID 20057060 DOI: 10.1107/S1744309109044315  0.364
2009 Kanaan AS, Frank F, Maedler-Kron C, Verma K, Sonenberg N, Nagar B. Crystallization and preliminary X-ray diffraction analysis of the middle domain of Paip1. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 1060-4. PMID 19851022 DOI: 10.1107/S1744309109036513  0.358
2007 Seeliger MA, Nagar B, Frank F, Cao X, Henderson MN, Kuriyan J. c-Src Binds to the Cancer Drug Imatinib with an Inactive Abl/c-Kit Conformation and a Distributed Thermodynamic Penalty Structure. 15: 299-311. PMID 17355866 DOI: 10.1016/J.Str.2007.01.015  0.708
2006 Kozlov G, Maattanen P, Schrag JD, Pollock S, Cygler M, Nagar B, Thomas DY, Gehring K. Crystal structure of the bb' domains of the protein disulfide isomerase ERp57. Structure (London, England : 1993). 14: 1331-9. PMID 16905107 DOI: 10.1016/J.Str.2006.06.019  0.361
2006 Nagar B, Hantschel O, Seeliger M, Davies JM, Weis WI, Superti-Furga G, Kuriyan J. Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase Molecular Cell. 21: 787-798. PMID 16543148 DOI: 10.1016/J.Molcel.2006.01.035  0.715
2005 Sondermann H, Nagar B, Bar-Sagi D, Kuriyan J. Computational docking and solution x-ray scattering predict a membrane-interacting role for the histone domain of the Ras activator son of sevenless Proceedings of the National Academy of Sciences of the United States of America. 102: 16632-16637. PMID 16267129 DOI: 10.1073/Pnas.0508315102  0.703
2005 Nagar B, Kuriyan J. SAXS and the working protein Structure. 13: 169-173. PMID 15698559 DOI: 10.1016/J.Str.2005.01.001  0.511
2004 Walker JR, Nagar B, Young NM, Hirama T, Rini JM. X-ray crystal structure of a galactose-specific C-type lectin possessing a novel decameric quaternary structure. Biochemistry. 43: 3783-92. PMID 15049685 DOI: 10.1021/Bi035871A  0.653
2003 Nagar B, Hantschel O, Young MA, Scheffzek K, Veach D, Bornmann W, Clarkson B, Superti-Furga G, Kuriyan J. Structural basis for the autoinhibition of c-Abl tyrosine kinase Cell. 112: 859-871. PMID 12654251 DOI: 10.1016/S0092-8674(03)00194-6  0.601
2003 Hantschel O, Nagar B, Guettler S, Kretzschmar J, Dorey K, Kuriyan J, Superti-Furga G. A myristoyl/phosphotyrosine switch regulates c-Abl Cell. 112: 845-857. PMID 12654250 DOI: 10.1016/S0092-8674(03)00191-0  0.587
2003 Margarit SM, Sondermann H, Hall BE, Nagar B, Hoelz A, Pirruccello M, Bar-Sagi D, Kuriyan J. Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS. Cell. 112: 685-95. PMID 12628188 DOI: 10.1016/S0092-8674(03)00149-1  0.636
2002 Shah NP, Nicoll JM, Nagar B, Gorre ME, Paquette RL, Kuriyan J, Sawyers CL. Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia. Cancer Cell. 2: 117-25. PMID 12204532 DOI: 10.1016/S1535-6108(02)00096-X  0.53
2002 Wisniewski D, Lambek CL, Liu C, Strife A, Veach DR, Nagar B, Young MA, Schindler T, Bornmann WG, Bertino JR, Kuriyan J, Clarkson B. Characterization of potent inhibitors of the Bcr-Abl and the c-kit receptor tyrosine kinases Cancer Research. 62: 4244-4255. PMID 12154026  0.464
2002 Nagar B, Bornmann WG, Pellicena P, Schindler T, Veach DR, Miller WT, Clarkson B, Kuriyan J. Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571). Cancer Research. 62: 4236-43. PMID 12154025 DOI: 10.2210/Pdb1Iep/Pdb  0.575
1998 Smith GD, Nagar B, Rini JM, Hauptman HA, Blessing RH. The use of SnB to determine an anomalous scattering substructure. Acta Crystallographica. Section D, Biological Crystallography. 54: 799-804. PMID 9757093 DOI: 10.1107/S0907444997018805  0.525
1998 Nagar B, Jones RG, Diefenbach RJ, Isenman DE, Rini JM. X-ray crystal structure of C3d: a C3 fragment and ligand for complement receptor 2. Science (New York, N.Y.). 280: 1277-81. PMID 9596584 DOI: 10.1126/Science.280.5367.1277  0.625
1998 Isenman D, Nagar B, Jones R, Clemenza L, Diefenbach R, Rini J. X-ray crystal structure of complement fragment C3d: The ligand for CR2 Molecular Immunology. 35: 359. DOI: 10.1016/S0161-5890(98)90645-9  0.571
1996 Nagar B, Overduin M, Ikura M, Rini JM. Structural basis of calcium-induced E-cadherin rigidification and dimerization. Nature. 380: 360-4. PMID 8598933 DOI: 10.1107/S0108767396092318  0.623
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