Bhushan Nagar, Ph.D. - Publications

Affiliations: 
2001 University of Toronto, Toronto, ON, Canada 
Area:
sturucture of glycosyltransferases

35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Frank F, Nagar B. Structural and Functional Characterization of Plant ARGONAUTE MID Domains. Methods in Molecular Biology (Clifton, N.J.). 1640: 227-239. PMID 28608347 DOI: 10.1007/978-1-4939-7165-7_17  0.32
2016 Gorelik A, Illes K, Superti-Furga G, Nagar B. Structural Basis for Nucleotide Hydrolysis by the Acid Sphingomyelinase-Like Phosphodiesterase SMPDL3A. The Journal of Biological Chemistry. PMID 26792860 DOI: 10.1074/jbc.M115.711085  0.44
2015 Liberman N, Gandin V, Svitkin YV, David M, Virgili G, Jaramillo M, Holcik M, Nagar B, Kimchi A, Sonenberg N. DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translation. Nucleic Acids Research. 43: 3764-75. PMID 25779044 DOI: 10.1093/nar/gkv205  0.44
2014 LeBlanc PM, Doggett TA, Choi J, Hancock MA, Durocher Y, Frank F, Nagar B, Ferguson TA, Saleh M. An immunogenic peptide in the A-box of HMGB1 protein reverses apoptosis-induced tolerance through RAGE receptor. The Journal of Biological Chemistry. 289: 7777-86. PMID 24474694 DOI: 10.1074/jbc.M113.541474  0.44
2013 Trempe JF, Sauvé V, Grenier K, Seirafi M, Tang MY, Ménade M, Al-Abdul-Wahid S, Krett J, Wong K, Kozlov G, Nagar B, Fon EA, Gehring K. Structure of parkin reveals mechanisms for ubiquitin ligase activation. Science (New York, N.Y.). 340: 1451-5. PMID 23661642 DOI: 10.1126/science.1237908  0.44
2013 Fabian MR, Frank F, Rouya C, Siddiqui N, Lai WS, Karetnikov A, Blackshear PJ, Nagar B, Sonenberg N. Structural basis for the recruitment of the human CCR4-NOT deadenylase complex by tristetraprolin. Nature Structural & Molecular Biology. 20: 735-9. PMID 23644599 DOI: 10.1038/nsmb.2572  0.44
2013 Ishiyama N, Tanaka N, Abe K, Yang YJ, Abbas YM, Umitsu M, Nagar B, Bueler SA, Rubinstein JL, Takeichi M, Ikura M. An autoinhibited structure of α-catenin and its implications for vinculin recruitment to adherens junctions. The Journal of Biological Chemistry. 288: 15913-25. PMID 23589308 DOI: 10.1074/jbc.M113.453928  0.44
2013 Virgili G, Frank F, Feoktistova K, Sawicki M, Sonenberg N, Fraser CS, Nagar B. Structural analysis of the DAP5 MIF4G domain and its interaction with eIF4A. Structure (London, England : 1993). 21: 517-27. PMID 23478064 DOI: 10.1016/j.str.2013.01.015  0.32
2013 Abbas YM, Pichlmair A, Górna MW, Superti-Furga G, Nagar B. Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins. Nature. 494: 60-4. PMID 23334420 DOI: 10.1038/nature11783  0.44
2013 Deleavey GF, Frank F, Hassler M, Wisnovsky S, Nagar B, Damha MJ. The 5' binding MID domain of human Argonaute2 tolerates chemically modified nucleotide analogues. Nucleic Acid Therapeutics. 23: 81-7. PMID 23289589 DOI: 10.1089/nat.2012.0393  0.44
2012 Frank F, Hauver J, Sonenberg N, Nagar B. Arabidopsis Argonaute MID domains use their nucleotide specificity loop to sort small RNAs. The Embo Journal. 31: 3588-95. PMID 22850669 DOI: 10.1038/emboj.2012.204  0.44
2011 Fabian MR, Cieplak MK, Frank F, Morita M, Green J, Srikumar T, Nagar B, Yamamoto T, Raught B, Duchaine TF, Sonenberg N. miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT. Nature Structural & Molecular Biology. 18: 1211-7. PMID 21984185 DOI: 10.1038/nsmb.2149  0.44
2011 Frank F, Fabian MR, Stepinski J, Jemielity J, Darzynkiewicz E, Sonenberg N, Nagar B. Structural analysis of 5'-mRNA-cap interactions with the human AGO2 MID domain. Embo Reports. 12: 415-20. PMID 21475248 DOI: 10.1038/embor.2011.48  0.44
2010 Frank F, Sonenberg N, Nagar B. Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2. Nature. 465: 818-22. PMID 20505670 DOI: 10.1038/nature09039  0.44
2010 Frank F, Virgili G, Sonenberg N, Nagar B. Crystallization and preliminary X-ray diffraction analysis of the MIF4G domain of DAP5. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 15-9. PMID 20057060 DOI: 10.1107/S1744309109044315  0.44
2009 Kanaan AS, Frank F, Maedler-Kron C, Verma K, Sonenberg N, Nagar B. Crystallization and preliminary X-ray diffraction analysis of the middle domain of Paip1. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 1060-4. PMID 19851022 DOI: 10.1107/S1744309109036513  0.44
2008 Nagar B. Structural biology in the battle against BCR-Abl Expert Opinion On Therapeutic Patents. 18: 975-988. DOI: 10.1517/13543776.18.9.975  0.44
2007 Nagar B. c-Abl tyrosine kinase and inhibition by the cancer drug imatinib (Gleevec/STI-571). The Journal of Nutrition. 137: 1518S-1523S; discuss. PMID 17513418  0.44
2007 Seeliger MA, Nagar B, Frank F, Cao X, Henderson MN, Kuriyan J. c-Src Binds to the Cancer Drug Imatinib with an Inactive Abl/c-Kit Conformation and a Distributed Thermodynamic Penalty Structure. 15: 299-311. PMID 17355866 DOI: 10.1016/j.str.2007.01.015  0.44
2006 Kozlov G, Maattanen P, Schrag JD, Pollock S, Cygler M, Nagar B, Thomas DY, Gehring K. Crystal structure of the bb' domains of the protein disulfide isomerase ERp57. Structure (London, England : 1993). 14: 1331-9. PMID 16905107 DOI: 10.1016/j.str.2006.06.019  0.44
2006 Nagar B, Hantschel O, Seeliger M, Davies JM, Weis WI, Superti-Furga G, Kuriyan J. Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase Molecular Cell. 21: 787-798. PMID 16543148 DOI: 10.1016/j.molcel.2006.01.035  0.44
2005 Sondermann H, Nagar B, Bar-Sagi D, Kuriyan J. Computational docking and solution x-ray scattering predict a membrane-interacting role for the histone domain of the Ras activator son of sevenless Proceedings of the National Academy of Sciences of the United States of America. 102: 16632-16637. PMID 16267129 DOI: 10.1073/pnas.0508315102  0.44
2005 Nagar B, Kuriyan J. SAXS and the working protein Structure. 13: 169-173. PMID 15698559 DOI: 10.1016/j.str.2005.01.001  0.44
2004 Walker JR, Nagar B, Young NM, Hirama T, Rini JM. X-ray crystal structure of a galactose-specific C-type lectin possessing a novel decameric quaternary structure. Biochemistry. 43: 3783-92. PMID 15049685 DOI: 10.1021/bi035871a  0.44
2003 Nagar B, Hantschel O, Young MA, Scheffzek K, Veach D, Bornmann W, Clarkson B, Superti-Furga G, Kuriyan J. Structural basis for the autoinhibition of c-Abl tyrosine kinase Cell. 112: 859-871. PMID 12654251 DOI: 10.1016/S0092-8674(03)00194-6  0.44
2003 Hantschel O, Nagar B, Guettler S, Kretzschmar J, Dorey K, Kuriyan J, Superti-Furga G. A myristoyl/phosphotyrosine switch regulates c-Abl Cell. 112: 845-857. PMID 12654250 DOI: 10.1016/S0092-8674(03)00191-0  0.44
2003 Margarit SM, Sondermann H, Hall BE, Nagar B, Hoelz A, Pirruccello M, Bar-Sagi D, Kuriyan J. Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS. Cell. 112: 685-95. PMID 12628188 DOI: 10.1016/S0092-8674(03)00149-1  0.44
2002 Shah NP, Nicoll JM, Nagar B, Gorre ME, Paquette RL, Kuriyan J, Sawyers CL. Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia. Cancer Cell. 2: 117-25. PMID 12204532 DOI: 10.1016/S1535-6108(02)00096-X  0.44
2002 Wisniewski D, Lambek CL, Liu C, Strife A, Veach DR, Nagar B, Young MA, Schindler T, Bornmann WG, Bertino JR, Kuriyan J, Clarkson B. Characterization of potent inhibitors of the Bcr-Abl and the c-kit receptor tyrosine kinases Cancer Research. 62: 4244-4255. PMID 12154026  0.44
2002 Nagar B, Bornmann WG, Pellicena P, Schindler T, Veach DR, Miller WT, Clarkson B, Kuriyan J. Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571). Cancer Research. 62: 4236-43. PMID 12154025  0.44
2001 Lee SY, Raha S, Nagar B, Robinson BH. The functional role of conserved acidic residues of the Qcr7 protein of the cytochrome bc(1) complex in Saccharomyces cerevisiae. Archives of Biochemistry and Biophysics. 393: 207-14. PMID 11556807 DOI: 10.1006/abbi.2001.2497  0.44
1998 Smith GD, Nagar B, Rini JM, Hauptman HA, Blessing RH. The use of SnB to determine an anomalous scattering substructure. Acta Crystallographica. Section D, Biological Crystallography. 54: 799-804. PMID 9757093 DOI: 10.1107/S0907444997018805  0.44
1998 Nagar B, Jones RG, Diefenbach RJ, Isenman DE, Rini JM. X-ray crystal structure of C3d: a C3 fragment and ligand for complement receptor 2. Science (New York, N.Y.). 280: 1277-81. PMID 9596584  0.44
1996 Nagar B, Overduin M, Ikura M, Rini JM. Structural basis of calcium-induced E-cadherin rigidification and dimerization. Nature. 380: 360-4. PMID 8598933 DOI: 10.1038/380360a0  0.44
1996 Nagar B, Overduin M, Ikura M, Rini JM. Structural basis of calcium-induced E-cadherin rigidification and dimerization Acta Crystallographica Section a Foundations of Crystallography. 52: C174-C174. DOI: 10.1107/S0108767396092318  0.32
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