Edward J. Merino, Ph.D. - Publications

Affiliations: 
2005 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Structural and Chemical Biology of the Transcriptome

31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zhu H, Mishra R, Yuan L, Abdul Salam SF, Liu J, Gray G, Sterling AD, Wunderlich M, Landero-Figueroa J, Garrett JT, Merino EJ. Oxidative Cyclization-Induced Activation of a Phosphoinositide 3-Kinase Inhibitor for Enhanced Selectivity of Cancer Chemotherapeutics. Chemmedchem. PMID 31696673 DOI: 10.1002/cmdc.201900481  0.44
2018 Liu J, Zhu H, Premnauth G, Earnest KG, Hahn P, Gray G, Queenan JA, Prevette LE, AbdulSalam SF, Kadekaro AL, Merino EJ. UV cell stress induces oxidative cyclization of a protective reagent for DNA damage reduction in skin explants. Free Radical Biology & Medicine. PMID 30605714 DOI: 10.1016/j.freeradbiomed.2018.12.037  0.44
2017 AbdulSalam SF, Gurjar PN, Zhu H, Johnson ES, Liu J, Kadekaro AL, Landero-Figueroa J, Merino EJ. Self-cyclizing Antioxidants to Prevent DNA Damage Caused by Hydroxyl Radical. Chembiochem : a European Journal of Chemical Biology. PMID 28810083 DOI: 10.1002/cbic.201700341  0.44
2016 Cushion MT, Collins MS, Sesterhenn T, Porollo A, Vadukoot AK, Merino EJ. Functional Characterization of Pneumocystis carinii Inositol Transporter 1. Mbio. 7. PMID 27965450 DOI: 10.1128/mBio.01851-16  0.44
2016 AbdulSalam SF, Thowfeik FS, Merino EJ. Excessive Reactive Oxygen Species and Exotic DNA Lesions as an Exploitable Liability. Biochemistry. PMID 27582430 DOI: 10.1021/acs.biochem.6b00703  0.44
2015 Thowfeik FS, Abdul Salam SF, Wunderlich M, Wyder M, Greis KD, Kadekaro AL, Mulloy JC, Merino EJ. A ROS-activatable agent elicits homologous recombination DNA repair and synergizes with pathway compounds. Chembiochem : a European Journal of Chemical Biology. PMID 26419938 DOI: 10.1002/cbic.201500304  1
2015 Borland KM, AbdulSalam SF, Solivio MJ, Burke MP, Wolfkiel PR, Lawson SM, Stockman CA, Andersen JM, Smith S, Tolstolutskaya JN, Gurjar PN, Bercz AP, Merino EJ, Litosh VA. Base-modified thymidines capable of terminating DNA synthesis are novel bioactive compounds with activity in cancer cells. Bioorganic & Medicinal Chemistry. 23: 1869-81. PMID 25778768 DOI: 10.1016/j.bmc.2015.01.057  1
2015 Gong J, Solivio MJ, Merino EJ, Caruso JA, Landero-Figueroa JA. Developing ICP-MS/MS for the detection and determination of synthetic DNA-protein crosslink models via phosphorus and sulfur detection. Analytical and Bioanalytical Chemistry. 407: 2433-7. PMID 25651903 DOI: 10.1007/s00216-015-8504-x  1
2014 Vadukoot AK, AbdulSalam SF, Wunderlich M, Pullen ED, Landero-Figueroa J, Mulloy JC, Merino EJ. Design of a hydrogen peroxide-activatable agent that specifically targets cancer cells. Bioorganic & Medicinal Chemistry. 22: 6885-92. PMID 25464887 DOI: 10.1016/j.bmc.2014.10.029  1
2014 Amato E, Bankemper T, Kidney R, Do T, Onate A, Thowfeik FS, Merino EJ, Paula S, Ma L. Investigation of fluorinated and bifunctionalized 3-phenylchroman-4-one (isoflavanone) aromatase inhibitors. Bioorganic & Medicinal Chemistry. 22: 126-34. PMID 24345481 DOI: 10.1016/j.bmc.2013.11.045  1
2014 Hufziger KT, Thowfeik FS, Charboneau DJ, Nieto I, Dougherty WG, Kassel WS, Dudley TJ, Merino EJ, Papish ET, Paul JJ. Ruthenium dihydroxybipyridine complexes are tumor activated prodrugs due to low pH and blue light induced ligand release. Journal of Inorganic Biochemistry. 130: 103-11. PMID 24184694 DOI: 10.1016/j.jinorgbio.2013.10.008  1
2013 Chitta KR, Landero-Figueroa JA, Kodali P, Caruso JA, Merino EJ. Identification of selenium-containing proteins in HEK 293 kidney cells using multiple chromatographies, LC-ICPMS and nano-LC-ESIMS. Talanta. 114: 25-31. PMID 23953436 DOI: 10.1016/j.talanta.2013.03.003  1
2013 Bell-Horwath TR, Vadukoot AK, Thowfeik FS, Li G, Wunderlich M, Mulloy JC, Merino EJ. Novel ROS-activated agents utilize a tethered amine to selectively target acute myeloid leukemia. Bioorganic & Medicinal Chemistry Letters. 23: 2951-4. PMID 23578690 DOI: 10.1016/j.bmcl.2013.03.048  1
2013 Chitta KR, Landero Figueroa JA, Caruso JA, Merino EJ. Selenium mediated arsenic toxicity modifies cytotoxicity, reactive oxygen species and phosphorylated proteins. Metallomics : Integrated Biometal Science. 5: 673-85. PMID 23503360 DOI: 10.1039/c3mt20213e  1
2012 Jones AR, Bell-Horwath TR, Li G, Rollmann SM, Merino EJ. Novel oxidatively activated agents modify DNA and are enhanced by ercc1 silencing. Chemical Research in Toxicology. 25: 2542-52. PMID 23051149 DOI: 10.1021/tx300337j  1
2012 Solivio MJ, Nemera DB, Sallans L, Merino EJ. Biologically relevant oxidants cause bound proteins to readily oxidatively cross-link at Guanine. Chemical Research in Toxicology. 25: 326-36. PMID 22216745 DOI: 10.1021/tx200376e  1
2011 Alp O, Zhang Y, Merino EJ, Caruso JA. Selenium effects on arsenic cytotoxicity and protein phosphorylation in human kidney cells using chip-based nanoLC-MS/MS. Metallomics : Integrated Biometal Science. 3: 482-90. PMID 21479294 DOI: 10.1039/c0mt00110d  1
2011 Li G, Bell T, Merino EJ. Oxidatively activated DNA-modifying agents for selective cytotoxicity. Chemmedchem. 6: 869-75. PMID 21374823 DOI: 10.1002/cmdc.201100014  1
2010 Alp O, Merino EJ, Caruso JA. Arsenic-induced protein phosphorylation changes in HeLa cells. Analytical and Bioanalytical Chemistry. 398: 2099-107. PMID 20803194 DOI: 10.1007/s00216-010-4128-3  1
2010 Solivio MJ, Joy TJ, Sallans L, Merino EJ. Copper generated reactive oxygen leads to formation of lysine-DNA adducts. Journal of Inorganic Biochemistry. PMID 20684846 DOI: 10.1016/j.jinorgbio.2010.05.006  1
2010 Solivio MJ, Joy TJ, Sallans L, Merino EJ. Copper generated reactive oxygen leads to formation of lysine-DNA adducts. Journal of Inorganic Biochemistry. 104: 1000-5. PMID 20684045  0.72
2006 Wilkinson KA, Merino EJ, Weeks KM. Selective 2'-hydroxyl acylation analyzed by primer extension (SHAPE): quantitative RNA structure analysis at single nucleotide resolution. Nature Protocols. 1: 1610-6. PMID 17406453 DOI: 10.1038/nprot.2006.249  1
2005 Merino EJ, Weeks KM. Facile conversion of aptamers into sensors using a 2'-ribose-linked fluorophore. Journal of the American Chemical Society. 127: 12766-7. PMID 16159247 DOI: 10.1021/ja053189t  1
2005 Wilkinson KA, Merino EJ, Weeks KM. RNA SHAPE chemistry reveals nonhierarchical interactions dominate equilibrium structural transitions in tRNA(Asp) transcripts. Journal of the American Chemical Society. 127: 4659-67. PMID 15796531 DOI: 10.1021/ja0436749  1
2005 Merino EJ, Wilkinson KA, Coughlan JL, Weeks KM. RNA structure analysis at single nucleotide resolution by selective 2'-hydroxyl acylation and primer extension (SHAPE). Journal of the American Chemical Society. 127: 4223-31. PMID 15783204 DOI: 10.1021/ja043822v  1
2004 John DM, Merino EJ, Weeks KM. Mechanics of DNA flexibility visualized by selective 2'-amine acylation at nucleotide bulges. Journal of Molecular Biology. 337: 611-9. PMID 15019781 DOI: 10.1016/j.jmb.2004.01.029  1
2003 Merino EJ, Weeks KM. Fluorogenic resolution of ligand binding by a nucleic acid aptamer. Journal of the American Chemical Society. 125: 12370-1. PMID 14531655 DOI: 10.1021/ja035299a  1
2002 Chamberlin SI, Merino EJ, Weeks KM. Catalysis of amide synthesis by RNA phosphodiester and hydroxyl groups. Proceedings of the National Academy of Sciences of the United States of America. 99: 14688-93. PMID 12403820 DOI: 10.1073/pnas.212527799  1
2001 Álvarez R, González P, Batalla A, Reguero JR, Iglesias-Cubero G, Hevia S, Cortina A, Merino E, González I, Alvarez V, Coto E. Association between the NOS3 (-786 T/C) and the ACE (I/D) DNA genotypes and early coronary artery disease Nitric Oxide - Biology and Chemistry. 5: 343-348. PMID 11485372 DOI: 10.1006/niox.2001.0351  1
2000 Sanmartín JC, Batalla A, Alvarez R, Reguero JJR, Cubero GI, Hevia S, Merino E, Cortina A, Coto E. Polymorphisms of the coagulation factor VII gene and risk of myocardial infarction. A case-control study Heart. 83: A9.  1
2000 Sanmartin JC, Batalla A, Alvarez R, Reguero JJR, Cubero GI, Hevia S, Merino E, Cortina A, Coto E. Concentrations of LDL cholesterol during the acute phase of myocardial infarction are predictors of new coronary events Heart. 83: A9.  1
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