Kurt H. Piepenbrink, Ph.D. - Publications

Affiliations: 
2011 University of Notre Dame, Notre Dame, IN, United States 
Area:
molecular recognition and cellular communication

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Pierce BG, Boucher EN, Piepenbrink KH, Ejemel M, Rapp CA, Thomas WD, Sundberg EJ, Weng Z, Wang Y. Structure-Based Design of Hepatitis C Virus Vaccines that Elicit Neutralizing Antibody Responses to a Conserved Epitope. Journal of Virology. PMID 28794021 DOI: 10.1128/JVI.01032-17  0.68
2017 Wang Y, Singh NK, Spear TT, Hellman LM, Piepenbrink KH, McMahan RH, Rosen HR, Vander Kooi CW, Nishimura MI, Baker BM. How an alloreactive T-cell receptor achieves peptide and MHC specificity. Proceedings of the National Academy of Sciences of the United States of America. PMID 28572406 DOI: 10.1073/pnas.1700459114  0.88
2016 Riley TP, Ayres CM, Hellman LM, Singh NK, Cosiano M, Cimons JM, Anderson MJ, Piepenbrink KH, Pierce BG, Weng Z, Baker BM. A generalized framework for computational design and mutational scanning of T-cell receptor binding interfaces. Protein Engineering, Design & Selection : Peds. PMID 27624308 DOI: 10.1093/protein/gzw050  0.88
2016 Hyun SW, Liu A, Liu Z, Cross AS, Verceles AC, Magesh S, Kommagalla Y, Kona C, Ando H, Luzina IG, Atamas SP, Piepenbrink KH, Sundberg EJ, Guang W, Ishida H, et al. The NEU1-selective sialidase inhibitor, C9-butyl-amide-DANA, blocks sialidase activity and NEU1-mediated bioactivities in human lung in vitro and murine lung in vivo. Glycobiology. PMID 27226251 DOI: 10.1093/glycob/cww060  0.88
2015 Kryshtafovych A, Moult J, Baslé A, Burgin A, Craig TK, Edwards RA, Fass D, Hartmann MD, Korycinski M, Lewis RJ, Lorimer D, Lupas AN, Newman J, Peat TS, Piepenbrink KH, et al. Some of the most interesting CASP11 targets through the eyes of their authors. Proteins. PMID 26473983 DOI: 10.1002/prot.24942  0.88
2015 Piepenbrink KH, Maldarelli GA, Martinez de la Peña CF, Dingle TC, Mulvey GL, Lee A, von Rosenvinge E, Armstrong GD, Donnenberg MS, Sundberg EJ. Structural and evolutionary analyses show unique stabilization strategies in the type IV pili of Clostridium difficile. Structure (London, England : 1993). 23: 385-96. PMID 25599642 DOI: 10.1016/j.str.2014.11.018  0.88
2014 Yang Z, Schmidt D, Liu W, Li S, Shi L, Sheng J, Chen K, Yu H, Tremblay JM, Chen X, Piepenbrink KH, Sundberg EJ, Kelly CP, Bai G, Shoemaker CB, et al. A novel multivalent, single-domain antibody targeting TcdA and TcdB prevents fulminant Clostridium difficile infection in mice. The Journal of Infectious Diseases. 210: 964-72. PMID 24683195 DOI: 10.1093/infdis/jiu196  0.88
2014 Piepenbrink KH, Maldarelli GA, de la Peña CF, Mulvey GL, Snyder GA, De Masi L, von Rosenvinge EC, Günther S, Armstrong GD, Donnenberg MS, Sundberg EJ. Structure of Clostridium difficile PilJ exhibits unprecedented divergence from known type IV pilins. The Journal of Biological Chemistry. 289: 4334-45. PMID 24362261 DOI: 10.1074/jbc.M113.534404  0.88
2013 Piao W, Ru LW, Piepenbrink KH, Sundberg EJ, Vogel SN, Toshchakov VY. Recruitment of TLR adapter TRIF to TLR4 signaling complex is mediated by the second helical region of TRIF TIR domain. Proceedings of the National Academy of Sciences of the United States of America. 110: 19036-41. PMID 24194546 DOI: 10.1073/pnas.1313575110  0.88
2013 Smith SN, Sommermeyer D, Piepenbrink KH, Blevins SJ, Bernhard H, Uckert W, Baker BM, Kranz DM. Plasticity in the contribution of T cell receptor variable region residues to binding of peptide-HLA-A2 complexes. Journal of Molecular Biology. 425: 4496-507. PMID 23954306 DOI: 10.1016/j.jmb.2013.08.007  0.88
2013 Piepenbrink KH, Blevins SJ, Scott DR, Baker BM. The basis for limited specificity and MHC restriction in a T cell receptor interface. Nature Communications. 4: 1948. PMID 23736024 DOI: 10.1038/ncomms2948  0.88
2012 Aggen DH, Chervin AS, Schmitt TM, Engels B, Stone JD, Richman SA, Piepenbrink KH, Baker BM, Greenberg PD, Schreiber H, Kranz DM. Single-chain VαVβ T-cell receptors function without mispairing with endogenous TCR chains. Gene Therapy. 19: 365-74. PMID 21753797 DOI: 10.1038/gt.2011.104  0.88
2011 Scott DR, Borbulevych OY, Piepenbrink KH, Corcelli SA, Baker BM. Disparate degrees of hypervariable loop flexibility control T-cell receptor cross-reactivity, specificity, and binding mechanism. Journal of Molecular Biology. 414: 385-400. PMID 22019736 DOI: 10.1016/j.jmb.2011.10.006  0.88
2011 Borbulevych OY, Piepenbrink KH, Baker BM. Conformational melding permits a conserved binding geometry in TCR recognition of foreign and self molecular mimics. Journal of Immunology (Baltimore, Md. : 1950). 186: 2950-8. PMID 21282516 DOI: 10.4049/jimmunol.1003150  0.88
2011 Aggen DH, Chervin AS, Insaidoo FK, Piepenbrink KH, Baker BM, Kranz DM. Identification and engineering of human variable regions that allow expression of stable single-chain T cell receptors. Protein Engineering, Design & Selection : Peds. 24: 361-72. PMID 21159619 DOI: 10.1093/protein/gzq113  0.88
2009 Piepenbrink KH, Gloor BE, Armstrong KM, Baker BM. Methods for quantifying T cell receptor binding affinities and thermodynamics. Methods in Enzymology. 466: 359-81. PMID 21609868 DOI: 10.1016/S0076-6879(09)66015-8  0.88
2009 Borbulevych OY, Piepenbrink KH, Gloor BE, Scott DR, Sommese RF, Cole DK, Sewell AK, Baker BM. T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility. Immunity. 31: 885-96. PMID 20064447 DOI: 10.1016/j.immuni.2009.11.003  0.88
2009 Piepenbrink KH, Borbulevych OY, Sommese RF, Clemens J, Armstrong KM, Desmond C, Do P, Baker BM. Fluorine substitutions in an antigenic peptide selectively modulate T-cell receptor binding in a minimally perturbing manner. The Biochemical Journal. 423: 353-61. PMID 19698083 DOI: 10.1042/BJ20090732  0.88
2008 Armstrong KM, Piepenbrink KH, Baker BM. Conformational changes and flexibility in T-cell receptor recognition of peptide-MHC complexes. The Biochemical Journal. 415: 183-96. PMID 18800968 DOI: 10.1042/BJ20080850  0.88
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