Year |
Citation |
Score |
2016 |
Brockway AJ, Cosner CC, Volkov OA, Phillips MA, De Brabander JK. Improved Synthesis of MDL 73811 - a Potent AdoMetDC Inhibitor and Anti-Trypanosomal Compound. Synthesis. 48: 2065-2068. PMID 27482123 DOI: 10.1055/s-0035-1561608 |
0.34 |
|
2014 |
Pearson GL, Mellett N, Chu KY, Cantley J, Davenport A, Bourbon P, Cosner CC, Helquist P, Meikle PJ, Biden TJ. Lysosomal acid lipase and lipophagy are constitutive negative regulators of glucose-stimulated insulin secretion from pancreatic beta cells. Diabetologia. 57: 129-39. PMID 24149836 DOI: 10.1007/S00125-013-3083-X |
0.632 |
|
2013 |
Ankner T, Cosner CC, Helquist P. Palladium- and nickel-catalyzed alkenylation of enolates Chemistry - a European Journal. 19: 1858-1871. PMID 23325616 DOI: 10.1002/chem.201202798 |
0.545 |
|
2013 |
Cosner CC, Bhaskara Reddy Iska V, Chatterjee A, Markiewicz JT, Corden SJ, Löfstedt J, Ankner T, Richer J, Hulett T, Schauer DJ, Wiest O, Helquist P. Evolution of concise and flexible synthetic strategies for trichostatic acid and the potent histone deacetylase inhibitor trichostatin A European Journal of Organic Chemistry. 162-172. DOI: 10.1002/Ejoc.201201233 |
0.513 |
|
2011 |
Cosner CC, Helquist P. Concise, convergent syntheses of (±)-trichostatin A utilizing a Pd-catalyzed ketone enolate α-alkenylation reaction. Organic Letters. 13: 3564-7. PMID 21688856 DOI: 10.1021/Ol200964M |
0.607 |
|
2011 |
Pipalia NH, Cosner CC, Huang A, Chatterjee A, Bourbon P, Farley N, Helquist P, Wiest O, Maxfield FR. Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 108: 5620-5. PMID 21436030 DOI: 10.1073/Pnas.1014890108 |
0.677 |
|
2011 |
Cosner CC, Cabrera PJ, Byrd KM, Thomas AM, Helquist P. Selective oxidation of benzylic and allylic alcohols using Mn(OAc)3/catalytic 2,3-dichloro-5,6-dicyano-1,4-benzoquinone. Organic Letters. 13: 2071-3. PMID 21395252 DOI: 10.1021/Ol200441G |
0.604 |
|
2010 |
Rosenbaum AI, Cosner CC, Mariani CJ, Maxfield FR, Wiest O, Helquist P. Thiadiazole carbamates: potent inhibitors of lysosomal acid lipase and potential Niemann-Pick type C disease therapeutics. Journal of Medicinal Chemistry. 53: 5281-9. PMID 20557099 DOI: 10.1021/Jm100499S |
0.67 |
|
2009 |
Cosner CC, Markiewicz JT, Bourbon P, Mariani CJ, Wiest O, Rujoi M, Rosenbaum AI, Huang AY, Maxfield FR, Helquist P. Investigation of N-aryl-3-alkylidenepyrrolinones as potential Niemann-Pick type C disease therapeutics. Journal of Medicinal Chemistry. 52: 6494-8. PMID 19772346 DOI: 10.1021/Jm900707N |
0.637 |
|
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